메뉴 건너뛰기




Volumn 1830, Issue 6, 2013, Pages 3584-3592

Transcriptional and post-translational regulation of Bim is essential for TGF-β and TNF-α-induced apoptosis of gastric cancer cell

Author keywords

Bim Apoptosis; c Jun; NH2 terminal kinase; Smad3; Transforming growth factor ; Tumor necrosis factor

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BIM PROTEIN; CASPASE 3; CASPASE 8; LUCIFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; SHORT HAIRPIN RNA; SMAD2 PROTEIN; SMAD3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84875970281     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.03.006     Document Type: Article
Times cited : (25)

References (51)
  • 1
    • 0242499448 scopus 로고    scopus 로고
    • Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
    • P.M. Siegel, and J. Massagué Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer Nat. Rev. Cancer 3 2003 807 821
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 807-821
    • Siegel, P.M.1    Massagué, J.2
  • 2
    • 27644449666 scopus 로고    scopus 로고
    • Transforming growth factor beta-dependent sequential activation of Smad, Bim, and caspase-9 mediates physiological apoptosis in gastric epithelial cells
    • M. Ohgushi, S. Kuroki, H. Fukamachi, L.A. O'Reilly, K. Kuida, A. Strasser, and S. Yonehara Transforming growth factor beta-dependent sequential activation of Smad, Bim, and caspase-9 mediates physiological apoptosis in gastric epithelial cells Mol. Cell. Biol. 25 2005 10017 10028
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 10017-10028
    • Ohgushi, M.1    Kuroki, S.2    Fukamachi, H.3    O'Reilly, L.A.4    Kuida, K.5    Strasser, A.6    Yonehara, S.7
  • 3
    • 0742270652 scopus 로고    scopus 로고
    • Transforming growth factor-beta 1 induces apoptosis through Fas ligand-independent activation of the Fas death pathway in human gastric SNU-620 carcinoma cells
    • S.G. Kim, H.-S. Jong, T.-Y. Kim, J.W. Lee, N.K. Kim, S.H. Hong, and Y.-J. Bang Transforming growth factor-beta 1 induces apoptosis through Fas ligand-independent activation of the Fas death pathway in human gastric SNU-620 carcinoma cells Mol. Biol. Cell 15 2004 420 434
    • (2004) Mol. Biol. Cell , vol.15 , pp. 420-434
    • Kim, S.G.1    Jong, H.-S.2    Kim, T.-Y.3    Lee, J.W.4    Kim, N.K.5    Hong, S.H.6    Bang, Y.-J.7
  • 5
    • 0038043227 scopus 로고    scopus 로고
    • Smad3 potentiates transforming growth factor beta (TGFbeta)-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes
    • G.M. Wildey, S. Patil, and P.H. Howe Smad3 potentiates transforming growth factor beta (TGFbeta)-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes J. Biol. Chem. 278 2003 18069 18077
    • (2003) J. Biol. Chem. , vol.278 , pp. 18069-18077
    • Wildey, G.M.1    Patil, S.2    Howe, P.H.3
  • 6
    • 0030032106 scopus 로고    scopus 로고
    • TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
    • H. Hsu, H.B. Shu, M.G. Pan, and D.V. Goeddel TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways Cell 84 1996 299 308
    • (1996) Cell , vol.84 , pp. 299-308
    • Hsu, H.1    Shu, H.B.2    Pan, M.G.3    Goeddel, D.V.4
  • 7
    • 0037204948 scopus 로고    scopus 로고
    • TNF-R1 signaling: A beautiful pathway
    • G. Chen, and D.V. Goeddel TNF-R1 signaling: a beautiful pathway Science 296 2002 1634 1635
    • (2002) Science , vol.296 , pp. 1634-1635
    • Chen, G.1    Goeddel, D.V.2
  • 9
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • L. Chang, and M. Karin Mammalian MAP kinase signalling cascades Nature 410 2001 37 40
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 10
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • R.J. Davis Signal transduction by the JNK group of MAP kinases Cell 103 2000 239 252
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 11
    • 33749076455 scopus 로고    scopus 로고
    • Mechanisms of crosstalk between TNF-induced NF-kappaB and JNK activation in hepatocytes
    • A. Wullaert, K. Heyninck, and R. Beyaert Mechanisms of crosstalk between TNF-induced NF-kappaB and JNK activation in hepatocytes Biochem. Pharmacol. 72 2006 1090 1101
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 1090-1101
    • Wullaert, A.1    Heyninck, K.2    Beyaert, R.3
  • 13
    • 14944348965 scopus 로고    scopus 로고
    • The role of BH3-only proteins in the immune system
    • A. Strasser The role of BH3-only proteins in the immune system Nat. Rev. Immunol. 5 2005 189 200
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 189-200
    • Strasser, A.1
  • 15
    • 0033607506 scopus 로고    scopus 로고
    • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
    • P. Bouillet, D. Metcalf, D.C. Huang, D.M. Tarlinton, T.W. Kay, F. Köntgen, J.M. Adams, and A. Strasser Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity Science 286 1999 1735 1738
    • (1999) Science , vol.286 , pp. 1735-1738
    • Bouillet, P.1    Metcalf, D.2    Huang, D.C.3    Tarlinton, D.M.4    Kay, T.W.5    Köntgen, F.6    Adams, J.M.7    Strasser, A.8
  • 16
    • 0037147122 scopus 로고    scopus 로고
    • Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation
    • S.C. Biswas, and L.A. Greene Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation J. Biol. Chem. 277 2002 49511 49516
    • (2002) J. Biol. Chem. , vol.277 , pp. 49511-49516
    • Biswas, S.C.1    Greene, L.A.2
  • 19
    • 4344613599 scopus 로고    scopus 로고
    • Quantitative real-time polymerase chain reaction measurement of regulators of G-protein signaling mRNA levels in mouse tissues
    • D.M. Kurrasch, J. Huang, T.M. Wilkie, and J.J. Repa Quantitative real-time polymerase chain reaction measurement of regulators of G-protein signaling mRNA levels in mouse tissues Methods Enzymol. 389 2004 3 15
    • (2004) Methods Enzymol. , vol.389 , pp. 3-15
    • Kurrasch, D.M.1    Huang, J.2    Wilkie, T.M.3    Repa, J.J.4
  • 20
    • 35148866130 scopus 로고    scopus 로고
    • Smad7 sensitizes tumor necrosis factor induced apoptosis through the inhibition of antiapoptotic gene expression by suppressing activation of the nuclear factor-kappaB pathway
    • S. Hong, C. Lee, and S.-J. Kim Smad7 sensitizes tumor necrosis factor induced apoptosis through the inhibition of antiapoptotic gene expression by suppressing activation of the nuclear factor-kappaB pathway Cancer Res. 67 2007 9577 9583
    • (2007) Cancer Res. , vol.67 , pp. 9577-9583
    • Hong, S.1    Lee, C.2    Kim, S.-J.3
  • 21
    • 0141953270 scopus 로고    scopus 로고
    • A JNK-dependent pathway is required for TNFalpha-induced apoptosis
    • Y. Deng, X. Ren, L. Yang, Y. Lin, and X. Wu A JNK-dependent pathway is required for TNFalpha-induced apoptosis Cell 115 2003 61 70
    • (2003) Cell , vol.115 , pp. 61-70
    • Deng, Y.1    Ren, X.2    Yang, L.3    Lin, Y.4    Wu, X.5
  • 22
    • 0037230304 scopus 로고    scopus 로고
    • Activation of the JNK signaling pathway: Breaking the brake on apoptosis
    • A. Lin Activation of the JNK signaling pathway: breaking the brake on apoptosis BioEssays 25 2003 17 24
    • (2003) BioEssays , vol.25 , pp. 17-24
    • Lin, A.1
  • 23
    • 0036716281 scopus 로고    scopus 로고
    • The Bcl2 family: Regulators of the cellular life-or-death switch
    • S. Cory, and J.M. Adams The Bcl2 family: regulators of the cellular life-or-death switch Nat. Rev. Cancer 2 2002 647 656
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 27
    • 0037418238 scopus 로고    scopus 로고
    • JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
    • K. Lei, and R.J. Davis JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis Proc. Natl. Acad. Sci. U. S. A. 100 2003 2432 2437
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 2432-2437
    • Lei, K.1    Davis, R.J.2
  • 28
    • 0030611189 scopus 로고    scopus 로고
    • C-Jun NH2-terminal kinase regulation of the apoptotic response of small cell lung cancer cells to ultraviolet radiation
    • L. Butterfield, B. Storey, L. Maas, and L.E. Heasley c-Jun NH2-terminal kinase regulation of the apoptotic response of small cell lung cancer cells to ultraviolet radiation J. Biol. Chem. 272 1997 10110 10116
    • (1997) J. Biol. Chem. , vol.272 , pp. 10110-10116
    • Butterfield, L.1    Storey, B.2    Maas, L.3    Heasley, L.E.4
  • 29
    • 0036765750 scopus 로고    scopus 로고
    • Regulation of platinum-compound cytotoxicity by the c-Jun N-terminal kinase and c-Jun signaling pathway in small-cell lung cancer cells
    • V. Levresse, L. Marek, D. Blumberg, and L.E. Heasley Regulation of platinum-compound cytotoxicity by the c-Jun N-terminal kinase and c-Jun signaling pathway in small-cell lung cancer cells Mol. Pharmacol. 62 2002 689 697
    • (2002) Mol. Pharmacol. , vol.62 , pp. 689-697
    • Levresse, V.1    Marek, L.2    Blumberg, D.3    Heasley, L.E.4
  • 30
    • 0038482050 scopus 로고    scopus 로고
    • Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim
    • R. Ley, K. Balmanno, K. Hadfield, C. Weston, and S.J. Cook Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim J. Biol. Chem. 278 2003 18811 18816
    • (2003) J. Biol. Chem. , vol.278 , pp. 18811-18816
    • Ley, R.1    Balmanno, K.2    Hadfield, K.3    Weston, C.4    Cook, S.J.5
  • 31
    • 68949094024 scopus 로고    scopus 로고
    • MEK/ERK-mediated phosphorylation of Bim is required to ensure survival of T and B lymphocytes during mitogenic stimulation
    • L.A. O'Reilly, E.A. Kruse, H. Puthalakath, P.N. Kelly, T. Kaufmann, D.C.S. Huang, and A. Strasser MEK/ERK-mediated phosphorylation of Bim is required to ensure survival of T and B lymphocytes during mitogenic stimulation J. Immunol. 183 2009 261 269
    • (2009) J. Immunol. , vol.183 , pp. 261-269
    • O'Reilly, L.A.1    Kruse, E.A.2    Puthalakath, H.3    Kelly, P.N.4    Kaufmann, T.5    Huang, D.C.S.6    Strasser, A.7
  • 32
    • 0033635989 scopus 로고    scopus 로고
    • Synergistic action between tumor necrosis factor-alpha and transforming growth factor type-beta: Consequences for natural antitumor mechanisms
    • A. Schulz, and G. Bauer Synergistic action between tumor necrosis factor-alpha and transforming growth factor type-beta: consequences for natural antitumor mechanisms Anticancer. Res. 20 2000 3443 3448
    • (2000) Anticancer. Res. , vol.20 , pp. 3443-3448
    • Schulz, A.1    Bauer, G.2
  • 33
  • 34
    • 0037036486 scopus 로고    scopus 로고
    • Synergistic induction of apoptosis in human endothelial cells by tumour necrosis factor-alpha and transforming growth factor-beta
    • C. Emmanuel, E. Foo, H.J. Medbury, J. Matthews, A. Comis, and H. Zoellner Synergistic induction of apoptosis in human endothelial cells by tumour necrosis factor-alpha and transforming growth factor-beta Cytokine 18 2002 237 241
    • (2002) Cytokine , vol.18 , pp. 237-241
    • Emmanuel, C.1    Foo, E.2    Medbury, H.J.3    Matthews, J.4    Comis, A.5    Zoellner, H.6
  • 35
    • 0028979251 scopus 로고
    • A synergistic relationship between TNF-alpha, IL-1 beta, and TGF-beta 1 on IL-6 secretion by the IEC-6 intestinal epithelial cell line
    • D.W. McGee, T. Bamberg, S.J. Vitkus, and J.R. McGhee A synergistic relationship between TNF-alpha, IL-1 beta, and TGF-beta 1 on IL-6 secretion by the IEC-6 intestinal epithelial cell line Immunology 86 1995 6 11
    • (1995) Immunology , vol.86 , pp. 6-11
    • McGee, D.W.1    Bamberg, T.2    Vitkus, S.J.3    McGhee, J.R.4
  • 36
    • 58249091117 scopus 로고    scopus 로고
    • Synergistic induction of nuclear factor-κB by transforming growth factor-β and tumour necrosis factor-α is mediated by protein kinase A-dependent RelA acetylation
    • H. Ishinaga, H. Jono, J.H. Lim, K. Komatsu, X. Xu, J. Lee, C.-H. Woo, H. Xu, X.-H. Feng, L.-F. Chen, C. Yan, and J.-D. Li Synergistic induction of nuclear factor-κB by transforming growth factor-β and tumour necrosis factor-α is mediated by protein kinase A-dependent RelA acetylation Biochem. J. 417 2009 583
    • (2009) Biochem. J. , vol.417 , pp. 583
    • Ishinaga, H.1    Jono, H.2    Lim, J.H.3    Komatsu, K.4    Xu, X.5    Lee, J.6    Woo, C.-H.7    Xu, H.8    Feng, X.-H.9    Chen, L.-F.10    Yan, C.11    Li, J.-D.12
  • 38
    • 23944486004 scopus 로고    scopus 로고
    • Signaling mechanism of TGF-β1 in prevention of renal inflammation: Role of Smad7
    • W. Wang, X.R. Huang, A.G. Li, F. Liu, J.-H. Li, L.D. Truong, X.J. Wang, and H.Y. Lan Signaling mechanism of TGF-β1 in prevention of renal inflammation: role of Smad7 JASN 16 2005 1371 1383
    • (2005) JASN , vol.16 , pp. 1371-1383
    • Wang, W.1    Huang, X.R.2    Li, A.G.3    Liu, F.4    Li, J.-H.5    Truong, L.D.6    Wang, X.J.7    Lan, H.Y.8
  • 39
    • 7044275192 scopus 로고    scopus 로고
    • Suppressed NF-κB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-α-induced apoptosis in human cancer cells
    • S. Zhang, Z.-N. Lin, C.-F. Yang, X. Shi, C.-N. Ong, and H.-M. Shen Suppressed NF-κB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-α-induced apoptosis in human cancer cells Carcinogenesis 25 2004 2191 2199
    • (2004) Carcinogenesis , vol.25 , pp. 2191-2199
    • Zhang, S.1    Lin, Z.-N.2    Yang, C.-F.3    Shi, X.4    Ong, C.-N.5    Shen, H.-M.6
  • 40
    • 0037743569 scopus 로고    scopus 로고
    • Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase
    • N.K. Sah, A. Munshi, J.F. Kurland, T.J. McDonnell, B. Su, and R.E. Meyn Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase J. Biol. Chem. 278 2003 20593 20602
    • (2003) J. Biol. Chem. , vol.278 , pp. 20593-20602
    • Sah, N.K.1    Munshi, A.2    Kurland, J.F.3    McDonnell, T.J.4    Su, B.5    Meyn, R.E.6
  • 41
    • 0029753773 scopus 로고    scopus 로고
    • The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and γ radiation. Duration of JNK activation may determine cell death and proliferation
    • Y.-R. Chen, X. Wang, D. Templeton, R.J. Davis, and T.-H. Tan The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and γ radiation. Duration of JNK activation may determine cell death and proliferation J. Biol. Chem. 271 1996 31929 31936
    • (1996) J. Biol. Chem. , vol.271 , pp. 31929-31936
    • Chen, Y.-R.1    Wang, X.2    Templeton, D.3    Davis, R.J.4    Tan, T.-H.5
  • 42
    • 0032512847 scopus 로고    scopus 로고
    • Correlation between sustained c-Jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-α in rat mesangial cells
    • Y.-L. Guo, K. Baysal, B. Kang, L.-J. Yang, and J.R. Williamson Correlation between sustained c-Jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-α in rat mesangial cells J. Biol. Chem. 273 1998 4027 4034
    • (1998) J. Biol. Chem. , vol.273 , pp. 4027-4034
    • Guo, Y.-L.1    Baysal, K.2    Kang, B.3    Yang, L.-J.4    Williamson, J.R.5
  • 44
    • 0032192236 scopus 로고    scopus 로고
    • Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF-beta in human normal lung epithelial cells
    • K. Yanagisawa, H. Osada, A. Masuda, M. Kondo, T. Saito, Y. Yatabe, K. Takagi, T. Takahashi, and T. Takahashi Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF-beta in human normal lung epithelial cells Oncogene 17 1998 1743 1747
    • (1998) Oncogene , vol.17 , pp. 1743-1747
    • Yanagisawa, K.1    Osada, H.2    Masuda, A.3    Kondo, M.4    Saito, T.5    Yatabe, Y.6    Takagi, K.7    Takahashi, T.8    Takahashi, T.9
  • 45
    • 0036173901 scopus 로고    scopus 로고
    • Transforming growth factor β1 induces apoptosis through cleavage of BAD in a Smad3-dependent mechanism in FaO hepatoma cells
    • B.-C. Kim, M. Mamura, K.S. Choi, B. Calabretta, and S.-J. Kim Transforming growth factor β1 induces apoptosis through cleavage of BAD in a Smad3-dependent mechanism in FaO hepatoma cells Mol. Cell. Biol. 22 2002 1369 1378
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 1369-1378
    • Kim, B.-C.1    Mamura, M.2    Choi, K.S.3    Calabretta, B.4    Kim, S.-J.5
  • 47
    • 11244305855 scopus 로고    scopus 로고
    • Inhibition of glucocorticoid-induced apoptosis by targeting the major splice variants of BIM mRNA with small interfering RNA and short hairpin RNA
    • M.T. Abrams, N.M. Robertson, K. Yoon, and E. Wickstrom Inhibition of glucocorticoid-induced apoptosis by targeting the major splice variants of BIM mRNA with small interfering RNA and short hairpin RNA J. Biol. Chem. 279 2004 55809 55817
    • (2004) J. Biol. Chem. , vol.279 , pp. 55809-55817
    • Abrams, M.T.1    Robertson, N.M.2    Yoon, K.3    Wickstrom, E.4
  • 48
    • 33644865025 scopus 로고    scopus 로고
    • Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function
    • X.-J. Qi, G.M. Wildey, and P.H. Howe Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function J. Biol. Chem. 281 2006 813 823
    • (2006) J. Biol. Chem. , vol.281 , pp. 813-823
    • Qi, X.-J.1    Wildey, G.M.2    Howe, P.H.3
  • 50
    • 1542275411 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinases 1/2 are serum-stimulated "bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover
    • R. Ley, K.E. Ewings, K. Hadfield, E. Howes, K. Balmanno, and S.J. Cook Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover J. Biol. Chem. 279 2004 8837 8847
    • (2004) J. Biol. Chem. , vol.279 , pp. 8837-8847
    • Ley, R.1    Ewings, K.E.2    Hadfield, K.3    Howes, E.4    Balmanno, K.5    Cook, S.J.6
  • 51
    • 0242521470 scopus 로고    scopus 로고
    • Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function
    • F. Luciano, A. Jacquel, P. Colosetti, M. Herrant, S. Cagnol, G. Pages, and P. Auberger Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function Oncogene 22 2003 6785 6793
    • (2003) Oncogene , vol.22 , pp. 6785-6793
    • Luciano, F.1    Jacquel, A.2    Colosetti, P.3    Herrant, M.4    Cagnol, S.5    Pages, G.6    Auberger, P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.