Synergistic induction of nuclear factor-κB by transforming growth factor-β and tumour necrosis factor-α is mediated by protein kinase A-dependent RelA acetylation

Biochemical Journal

Volumn 417, Issue 2, 2009, Pages 583-591

  Ishinaga, Hajime ^a   Jono, Hirofumi ^a   Lim, Jae Hyang ^a   Komatsu, Kensei ^a   Xu, Xiangbin ^a   Lee, Jiyun ^a   Woo, Chang Hoon ^a   Xu, Haidong ^a   Feng, Xin Hua ^b   Chen, Lin Feng ^c   Yan, Chen ^a   Li, Jian Dong ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Inflammatory response; Nuclear factor B (NF B); Protein kinase A (PKA); RelA acetylation; Transforming growthfactor 1 (TGF 1); Tumour necrosis factor (TNF )

Indexed keywords

BIOLOGICAL PROCESS; DNA BINDING ACTIVITY; DNA-BINDING; IN-VITRO; INFLAMMATORY RESPONSE; NECROSIS FACTORS; NUCLEAR FACTORS; PKA (PROTEIN KINASE A); PROINFLAMMATORY CYTOKINE; PROTEIN KINASE A; PROTEIN KINASE A (PKA); RELA ACETYLATION; SIGNALLING PATHWAYS; SYNERGISTIC ENHANCEMENT; TRANSFORMING GROWTH FACTORS;

ACETYLATION; BINDING SITES; BIOACTIVITY; CELL PROLIFERATION; DNA; GENES; GLYCOPROTEINS; MACROPHAGES; NUCLEIC ACIDS; PEPTIDES;

TUMORS;

CYCLIC AMP DEPENDENT PROTEIN KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; DNA; TRANSFORMING GROWTH FACTOR BETA;

ACETYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LUNG ALVEOLUS EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS REGULATION; SIGNAL TRANSDUCTION; DRUG EFFECT; GENETICS; METABOLISM; PROTEIN BINDING; TUMOR CELL LINE;

ACETYLATION; CELL LINE, TUMOR; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA; HUMANS; NF-KAPPA B; PROTEIN BINDING; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 58249091117     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20080781     Document Type: Article

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