메뉴 건너뛰기




Volumn 20, Issue 4, 2013, Pages 378-385

Matrix metalloproteinase-inspired suicidal treatments of diabetic ulcers with siRNA-decorated nanofibrous meshes

Author keywords

diabetic ulcer; matrix metalloproteinase; nanofiber; siRNA; wound healing

Indexed keywords

GELATINASE A; NANOFIBER; POLYETHYLENEIMINE; SMALL INTERFERING RNA;

EID: 84875959104     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2012.49     Document Type: Article
Times cited : (61)

References (39)
  • 3
    • 0027235550 scopus 로고
    • Long-term prognosis for diabetic patients with foot ulcers
    • Apelqvist J, Larsson J, Agardh CD. Long-term prognosis for diabetic patients with foot ulcers. J Intern Med 1993; 233: 485-491.
    • (1993) J Intern Med , vol.233 , pp. 485-491
    • Apelqvist, J.1    Larsson, J.2    Agardh, C.D.3
  • 4
    • 0036020282 scopus 로고    scopus 로고
    • Expression of matrix-metalloproteinases and their inhibitors in the wounds of diabetic and non-diabetic patients
    • Lobmann R, Ambrosch A, Schultz G, Waldmann K, Schiweck S, Lehnert H. Expression of matrix-metalloproteinases and their inhibitors in the wounds of diabetic and non-diabetic patients. Diabetologia 2002; 45: 1011-1016.
    • (2002) Diabetologia , vol.45 , pp. 1011-1016
    • Lobmann, R.1    Ambrosch, A.2    Schultz, G.3    Waldmann, K.4    Schiweck, S.5    Lehnert, H.6
  • 5
    • 12844249318 scopus 로고    scopus 로고
    • Proteases and the diabetic foot syndrome: Mechanisms and therapeutic implications
    • Lobmann R, Schults G, Lehnert H. Proteases and the diabetic foot syndrome: mechanisms and therapeutic implications. Diabetes care 2005; 28: 461-471.
    • (2005) Diabetes Care , vol.28 , pp. 461-471
    • Lobmann, R.1    Schults, G.2    Lehnert, H.3
  • 6
    • 0027202705 scopus 로고
    • Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9
    • Wysocki AB, Staiano-Coico L, Grinnell F. Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9. J Invest Dermatol 1993; 101: 64-68.
    • (1993) J Invest Dermatol , vol.101 , pp. 64-68
    • Wysocki, A.B.1    Staiano-Coico, L.2    Grinnell, F.3
  • 7
    • 0347725622 scopus 로고    scopus 로고
    • Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors
    • Yager DR, Chen S, Ward SI, Olutoye OO, Diegelmann RF, Cohen IK. Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors. Wound Rep Reg 1997; 5: 23-32.
    • (1997) Wound Rep Reg , vol.5 , pp. 23-32
    • Yager, D.R.1    Chen, S.2    Ward, S.I.3    Olutoye, O.O.4    Diegelmann, R.F.5    Cohen, I.K.6
  • 8
    • 0033376144 scopus 로고    scopus 로고
    • Analysis of the acute and chronic wound environments the role of proteases and their inhibitors
    • Trengove NJ, Stacey MC, Macauley S, Bennett N, Gibson J, Burslem F et al. Analysis of the acute and chronic wound environments the role of proteases and their inhibitors. Wound Rep Reg 1997; 7: 442-452.
    • (1997) Wound Rep Reg , vol.7 , pp. 442-452
    • Trengove, N.J.1    Stacey, M.C.2    MacAuley, S.3    Bennett, N.4    Gibson, J.5    Burslem, F.6
  • 9
    • 0033910462 scopus 로고    scopus 로고
    • Expression and proteolysis of vascular endothelial growth factor is increased in chronic wounds
    • Lauer G, Sollberg S, Cole M, Flamme I, Stu+rzebecher J, Mann K et al. Expression and proteolysis of vascular endothelial growth factor is increased in chronic wounds. J Invest Dermatol 2000; 115: 12-18.
    • (2000) J Invest Dermatol , vol.115 , pp. 12-18
    • Lauer, G.1    Sollberg, S.2    Cole, M.3    Flamme, I.4    Sturzebecher, J.5    Mann, K.6
  • 10
  • 11
    • 0347477300 scopus 로고    scopus 로고
    • Thermosensitive hydrogel as a TGF-b1 gene delivery vehicle enhances diabetic wound healing
    • Lee P, Li Z, Huang L. Thermosensitive hydrogel as a TGF-b1 gene delivery vehicle enhances diabetic wound healing. Pharm Res 2003; 20: 1995-2000.
    • (2003) Pharm Res , vol.20 , pp. 1995-2000
    • Lee, P.1    Li, Z.2    Huang, L.3
  • 12
    • 0027945437 scopus 로고
    • In vivo transfer and expression of a human epidermal growth factor gene accelerates wound repair
    • Andree C, Swain WF, Page CP, Macklin MD, Slama J, Hatzis D et al. In vivo transfer and expression of a human epidermal growth factor gene accelerates wound repair. Proc Natl Acad Sci USA 1994; 91: 12188-12192.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12188-12192
    • Andree, C.1    Swain, W.F.2    Page, C.P.3    MacKlin, M.D.4    Slama, J.5    Hatzis, D.6
  • 16
    • 0038748037 scopus 로고    scopus 로고
    • Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model
    • Reich SJ, Fosnot J, Kuroki A, Tang W, Yang X, Maguire AM et al. Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model. Mol Vis 2003; 9: 210-216.
    • (2003) Mol Vis , vol.9 , pp. 210-216
    • Reich, S.J.1    Fosnot, J.2    Kuroki, A.3    Tang, W.4    Yang, X.5    Maguire, A.M.6
  • 17
    • 33847720312 scopus 로고    scopus 로고
    • In vivo imaging of siRNA delivery and silencing in tumors
    • Medarova Z, Pham W, Farrar C, Petkova V, Moore A. In vivo imaging of siRNA delivery and silencing in tumors. Nat Med 2007; 13: 372-377.
    • (2007) Nat Med , vol.13 , pp. 372-377
    • Medarova, Z.1    Pham, W.2    Farrar, C.3    Petkova, V.4    Moore, A.5
  • 18
    • 11844283922 scopus 로고    scopus 로고
    • Gene knockdown with intrathecal siRNA of NMDA receptor NR2B subunit reduces formalin-induced nociception in the rat
    • Tan PH, Yang LC, Shih HC, Lan KC, Cheng JT. Gene knockdown with intrathecal siRNA of NMDA receptor NR2B subunit reduces formalin-induced nociception in the rat. Gene Therapy 2005; 12: 59-66.
    • (2005) Gene Therapy , vol.12 , pp. 59-66
    • Tan, P.H.1    Yang, L.C.2    Shih, H.C.3    Lan, K.C.4    Cheng, J.T.5
  • 19
    • 13544265637 scopus 로고    scopus 로고
    • Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery
    • Golzio M, Mazzolini L, Moller P, Rols MP, Teissie J. Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery. Gene Therapy 2005; 12: 246-251.
    • (2005) Gene Therapy , vol.12 , pp. 246-251
    • Golzio, M.1    Mazzolini, L.2    Moller, P.3    Rols, M.P.4    Teissie, J.5
  • 20
    • 77957980821 scopus 로고    scopus 로고
    • Local arterial nanoparticle delivery of sirna for nox2 knockdown to prevent restenosis in an atherosclerotic rat model
    • Li JM, Newburger PE, Gounis M, Dargon P, Zhang X, Messina LM. Local arterial nanoparticle delivery of siRNA for NOX2 knockdown to prevent restenosis in an atherosclerotic rat model. Gene Therapy 2010; 17: 1279-1287.
    • (2010) Gene Therapy , vol.17 , pp. 1279-1287
    • Li, J.M.1    Newburger, P.E.2    Gounis, M.3    Dargon, P.4    Zhang, X.5    Messina, L.M.6
  • 21
    • 80054083256 scopus 로고    scopus 로고
    • Local delivery of sirna using a biodegradable polymer application to enhance bmp-induced bone formation
    • Manaka T, Suzuki A, Takayama K, Imai Y, Nakamura H, Takaoka K. Local delivery of siRNA using a biodegradable polymer application to enhance BMP-induced bone formation. Biomaterials 2011; 32: 9642-9648.
    • (2011) Biomaterials , vol.32 , pp. 9642-9648
    • Manaka, T.1    Suzuki, A.2    Takayama, K.3    Imai, Y.4    Nakamura, H.5    Takaoka, K.6
  • 22
    • 36048959183 scopus 로고    scopus 로고
    • In vivo wound healing of diabetic ulcers using electrospun nanofibers immobilized with human epidermal growth factor (EGF)
    • Choi JS, Leong KW, Yoo HS. In vivo wound healing of diabetic ulcers using electrospun nanofibers immobilized with human epidermal growth factor (EGF). Biometerials 2008; 29: 587-596.
    • (2008) Biometerials , vol.29 , pp. 587-596
    • Choi, J.S.1    Leong, K.W.2    Yoo, H.S.3
  • 23
    • 79954572850 scopus 로고    scopus 로고
    • Coaxial electrospun nanofibers for treatment of diabetic ulcers with binary release of multiple growth factors
    • Choi JS, Choi SH, Yoo HS. Coaxial electrospun nanofibers for treatment of diabetic ulcers with binary release of multiple growth factors. J Mater Chem 2011; 21: 5258-5267.
    • (2011) J Mater Chem , vol.21 , pp. 5258-5267
    • Choi, J.S.1    Choi, S.H.2    Yoo, H.S.3
  • 24
    • 77954314510 scopus 로고    scopus 로고
    • MMPs-responsive release of DNA from electrospun nanofibrous matrix for local gene therapy: In vitro and in vivo evaluation
    • Kim HS, Yoo HS. MMPs-responsive release of DNA from electrospun nanofibrous matrix for local gene therapy: In vitro and in vivo evaluation. J control Release 2010; 145: 264-271.
    • (2010) J Control Release , vol.145 , pp. 264-271
    • Kim, H.S.1    Yoo, H.S.2
  • 25
    • 77249154018 scopus 로고    scopus 로고
    • Multimeric small interfering ribonucleic acid for highly efficient sequence-specific gene silencing
    • Mok H, Lee SH, Park JW, Park TG. Multimeric small interfering ribonucleic acid for highly efficient sequence-specific gene silencing. Nat Mat 2010; 9: 272-278.
    • (2010) Nat Mat , vol.9 , pp. 272-278
    • Mok, H.1    Lee, S.H.2    Park, J.W.3    Park, T.G.4
  • 26
    • 75549089094 scopus 로고    scopus 로고
    • Stability and cellular uptake of polymerized siRNA (poly-siRNA)/ polyethylenimine (PEI) complexes for efficient gene silencing
    • Lee S, Huh MS, Lee S, Lee SJ, Chung H, Park JH et al. Stability and cellular uptake of polymerized siRNA (poly-siRNA)/polyethylenimine (PEI) complexes for efficient gene silencing. J control Release 2010; 141: 339-346.
    • (2010) J Control Release , vol.141 , pp. 339-346
    • Lee, S.1    Huh, M.S.2    Lee, S.3    Lee, S.J.4    Chung, H.5    Park, J.H.6
  • 27
    • 67349175996 scopus 로고    scopus 로고
    • Multilayer mediated forward and patterned siRNA transfection using linear-PEI at extended N/P ratios
    • Mehrotra S, Lee I, Chan C. Multilayer mediated forward and patterned siRNA transfection using linear-PEI at extended N/P ratios. Acta Biomater 2009; 5: 1474-1488.
    • (2009) Acta Biomater , vol.5 , pp. 1474-1488
    • Mehrotra, S.1    Lee, I.2    Chan, C.3
  • 28
    • 15444373116 scopus 로고    scopus 로고
    • RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-com-plexed siRNA in vivo
    • Urban-Klein B, Werth S, Abuharbeid S, Czubayko F, Aigner A. RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-com-plexed siRNA in vivo. Gene Ther 2005; 12: 461-466.
    • (2005) Gene Ther , vol.12 , pp. 461-466
    • Urban-Klein, B.1    Werth, S.2    Abuharbeid, S.3    Czubayko, F.4    Aigner, A.5
  • 29
    • 33646152761 scopus 로고    scopus 로고
    • A low molecular weight fraction of polyethylenimine (PEI) displays increased transfec-tion efficiency of DNA and siRNA in fresh or lyophilized complexes
    • Werth S, Urban-Klein B, Dai L, Höbel S, Grzelinski M, Bakowsky U et al. A low molecular weight fraction of polyethylenimine (PEI) displays increased transfec-tion efficiency of DNA and siRNA in fresh or lyophilized complexes. J Control Release 2006; 112: 257-270.
    • (2006) J Control Release , vol.112 , pp. 257-270
    • Werth, S.1    Urban-Klein, B.2    Dai, L.3    Höbel, S.4    Grzelinski, M.5    Bakowsky, U.6
  • 31
    • 67649865399 scopus 로고    scopus 로고
    • The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice
    • Gao S, Dagnaes-Hansen F, Nielsen EJB, Wengel J, Besenbacher F, Howard KA et al. The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice. Mol Ther 2009; 17: 1225-1233.
    • (2009) Mol Ther , vol.17 , pp. 1225-1233
    • Gao, S.1    Dagnaes-Hansen, F.2    Nielsen, E.J.B.3    Wengel, J.4    Besenbacher, F.5    Howard, K.A.6
  • 32
    • 0023996345 scopus 로고
    • Porous Collagen Sponge Wound Dressings: In vivo and in vitro Studies
    • Doillon CJ. Porous Collagen Sponge Wound Dressings: in vivo and in vitro Studies. J Biomater Appl 1987; 2: 562-578.
    • (1987) J Biomater Appl , vol.2 , pp. 562-578
    • Doillon, C.J.1
  • 33
    • 0021294380 scopus 로고
    • Fibroblast-collagen sponge interactions and the spatial deposition of newly synthesized collagen fibers in vitro and in vivo
    • Doillon CJ, Whyne CF, Berg RA, Olson RM, Silver FH. Fibroblast-collagen sponge interactions and the spatial deposition of newly synthesized collagen fibers in vitro and in vivo. Scan Electron Microsc 1984; 3: 1313-1320.
    • (1984) Scan Electron Microsc , vol.3 , pp. 1313-1320
    • Doillon, C.J.1    Whyne, C.F.2    Berg, R.A.3    Olson, R.M.4    Silver, F.H.5
  • 36
    • 28444435248 scopus 로고    scopus 로고
    • Electrospinning of collagen nanofibers: Effects on the behavior of normal human keratinocytes and early-stage wound healing
    • Rhoa KS, Jeong L, Lee G, Seo B, Park YJ, Hong S et al. Electrospinning of collagen nanofibers: Effects on the behavior of normal human keratinocytes and early-stage wound healing. Biomaterials 2006; 27: 1452-1461.
    • (2006) Biomaterials , vol.27 , pp. 1452-1461
    • Rhoa, K.S.1    Jeong, L.2    Lee, G.3    Seo, B.4    Park, Y.J.5    Hong, S.6
  • 37
    • 0033606774 scopus 로고    scopus 로고
    • Airway epithelial cell migration dynamics: MMP-9 role in cell-extracellular matrix remodeling
    • Legrand C, Gilles C, Zahm J, Polette M, Buisson A, Kaplan H et al. Airway epithelial cell migration dynamics: MMP-9 role in cell-extracellular matrix remodeling. J Cell Biol 1999; 146: 517-529.
    • (1999) J Cell Biol , vol.146 , pp. 517-529
    • Legrand, C.1    Gilles, C.2    Zahm, J.3    Polette, M.4    Buisson, A.5    Kaplan, H.6
  • 38
  • 39
    • 0345411593 scopus 로고    scopus 로고
    • Matrix metalloproteinase 2 (gelatinase A) is related to migration of keratinocytes
    • Mäkelä M, Larjava H, Pirilä E, Maisi P, Salo T, Sorsa T et al. Matrix metalloproteinase 2 (gelatinase A) is related to migration of keratinocytes. Exp Cell Res 1999; 251: 67-78.
    • (1999) Exp Cell Res , vol.251 , pp. 67-78
    • Mäkelä, M.1    Larjava, H.2    Pirilä, E.3    Maisi, P.4    Salo, T.5    Sorsa, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.