메뉴 건너뛰기




Volumn 5, Issue 1, 1997, Pages 23-32

Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors

Author keywords

[No Author keywords available]

Indexed keywords


EID: 0347725622     PISSN: 10671927     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1524-475X.1997.50108.x     Document Type: Article
Times cited : (253)

References (55)
  • 1
    • 0024389941 scopus 로고
    • Growth factors in wound healing: Single and synergistic effects on partial thickness porcine skin wounds
    • Lynch SE, Colvin RB, Antoniades HN. Growth factors in wound healing: single and synergistic effects on partial thickness porcine skin wounds. J Clin Invest 1989;84:640-6.
    • (1989) J Clin Invest , vol.84 , pp. 640-646
    • Lynch, S.E.1    Colvin, R.B.2    Antoniades, H.N.3
  • 3
    • 0025359279 scopus 로고
    • PDGF and FGF stimulate wound healing in the genetically diabetic mouse
    • Greenhalgh DG, Sprugel KH, Murray MJ, Ross R. PDGF and FGF stimulate wound healing in the genetically diabetic mouse. Am J Pathol 1990;136:1235-46.
    • (1990) Am J Pathol , vol.136 , pp. 1235-1246
    • Greenhalgh, D.G.1    Sprugel, K.H.2    Murray, M.J.3    Ross, R.4
  • 5
    • 0024441779 scopus 로고
    • Reversal of impaired wound healing in irradiated rats by platelet-derived growth factor-BB: Requirement of an active bone marrow
    • Mustoe TA, Purdy J, Gramates P, Deuel TF, Thomason A, Pierce GF. Reversal of impaired wound healing in irradiated rats by platelet-derived growth factor-BB: requirement of an active bone marrow. Am J Surg 1989;158:345-50.
    • (1989) Am J Surg , vol.158 , pp. 345-350
    • Mustoe, T.A.1    Purdy, J.2    Gramates, P.3    Deuel, T.F.4    Thomason, A.5    Pierce, G.F.6
  • 8
    • 0028790881 scopus 로고
    • Suppression of keratinocyte growth factor expression by glucocorticoids in vitro and during wound healing
    • Brauchle M, Fässler R, Werner S. Suppression of keratinocyte growth factor expression by glucocorticoids in vitro and during wound healing. J Invest Dermatol 1995;105:579-84.
    • (1995) J Invest Dermatol , vol.105 , pp. 579-584
    • Brauchle, M.1    Fässler, R.2    Werner, S.3
  • 12
    • 0024594301 scopus 로고
    • Fibroblast growth factors
    • Baird A, Walicke PA. Fibroblast growth factors. Med Bulletin 1989;45:438-52.
    • (1989) Med Bulletin , vol.45 , pp. 438-452
    • Baird, A.1    Walicke, P.A.2
  • 16
    • 0024337366 scopus 로고
    • EGF and TGF-alpha are potent chemoattractants for endothelial cells and EGF-like peptides are present at sites of tissue regeneration
    • Grotendorst GR, Soma Y, Takehara K, Charette H. EGF and TGF-alpha are potent chemoattractants for endothelial cells and EGF-like peptides are present at sites of tissue regeneration. J Cell Physiol 1989;139:617-23.
    • (1989) J Cell Physiol , vol.139 , pp. 617-623
    • Grotendorst, G.R.1    Soma, Y.2    Takehara, K.3    Charette, H.4
  • 17
    • 0025021033 scopus 로고
    • Stimulation of repair in chronic, nonhealing, cutaneous ulcers using platelet-derived wound healing formula
    • Knighton DR, Ciresi K, Fiegel VD, Schumerth S, Butler E, Cerra F. Stimulation of repair in chronic, nonhealing, cutaneous ulcers using platelet-derived wound healing formula. Surg Gynecol Obstet 1990;170:56-60.
    • (1990) Surg Gynecol Obstet , vol.170 , pp. 56-60
    • Knighton, D.R.1    Ciresi, K.2    Fiegel, V.D.3    Schumerth, S.4    Butler, E.5    Cerra, F.6
  • 18
    • 0026589209 scopus 로고
    • Human recombinant transforming growth factor-β1 modulation of biochemical and cellular events in healing of ulcer wounds
    • Chen TL, Bates RL, Xu Y, Ammann AJ, Beck LS. Human recombinant transforming growth factor-β1 modulation of biochemical and cellular events in healing of ulcer wounds. J Invest Dermatol 1992;98:428-35.
    • (1992) J Invest Dermatol , vol.98 , pp. 428-435
    • Chen, T.L.1    Bates, R.L.2    Xu, Y.3    Ammann, A.J.4    Beck, L.S.5
  • 21
    • 0025033429 scopus 로고
    • Use of homologous platelet factors in achieving total healing of recalcitrant skin ulcers
    • Atri SC, Misra J, Bisht D, Misra K. Use of homologous platelet factors in achieving total healing of recalcitrant skin ulcers. Surgery 1990;108:508-12.
    • (1990) Surgery , vol.108 , pp. 508-512
    • Atri, S.C.1    Misra, J.2    Bisht, D.3    Misra, K.4
  • 23
    • 0026496037 scopus 로고
    • Collagen types I and III propeptides as markers of healing in chronic leg ulcers. A noninvasive method for the determination of procollagen propeptides in wound fluid - Influence of growth hormone
    • Rasmussen LH, Jensen LT, Avnstorp C, Karlsmark T, Peters K, Horslev-Petersen K. Collagen types I and III propeptides as markers of healing in chronic leg ulcers. A noninvasive method for the determination of procollagen propeptides in wound fluid - influence of growth hormone. Ann Surg 1992;216: 684-91.
    • (1992) Ann Surg , vol.216 , pp. 684-691
    • Rasmussen, L.H.1    Jensen, L.T.2    Avnstorp, C.3    Karlsmark, T.4    Peters, K.5    Horslev-Petersen, K.6
  • 24
    • 0029439509 scopus 로고
    • Oxidative stress: The paradox of aerobic life
    • Davies KJ. Oxidative stress: the paradox of aerobic life. Biochem Soc Symp 1995;61:1-31.
    • (1995) Biochem Soc Symp , vol.61 , pp. 1-31
    • Davies, K.J.1
  • 27
    • 0027202705 scopus 로고
    • Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9
    • Wysocki AB, Staiano-Coico L, Grinnell F. Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9. J Invest Dermatol 1993;101:64-8.
    • (1993) J Invest Dermatol , vol.101 , pp. 64-68
    • Wysocki, A.B.1    Staiano-Coico, L.2    Grinnell, F.3
  • 28
    • 0029823105 scopus 로고    scopus 로고
    • Wound fluids from human pressure ulcers contain elevated matrix metalloproteinase level and activity compared to surgical wound fluids
    • Yager DR, Zhang L-Y, Liang H-X, Diegelmann RF, Cohen IK. Wound fluids from human pressure ulcers contain elevated matrix metalloproteinase level and activity compared to surgical wound fluids. J Invest Dermatol 1996;107:743-8.
    • (1996) J Invest Dermatol , vol.107 , pp. 743-748
    • Yager, D.R.1    Zhang, L.-Y.2    Liang, H.-X.3    Diegelmann, R.F.4    Cohen, I.K.5
  • 29
    • 84989023323 scopus 로고
    • Involvement of proteolytic enzymes - plasminogen activators and matrix metalloproteinases - In the pathophysiology of pressure ulcers
    • Rogers AA, Burnett S, Moore JC, Shakespeare PG, Chen WYJ. Involvement of proteolytic enzymes - plasminogen activators and matrix metalloproteinases - in the pathophysiology of pressure ulcers. Wound Rep Reg 1995;3:273-83.
    • (1995) Wound Rep Reg , vol.3 , pp. 273-283
    • Rogers, A.A.1    Burnett, S.2    Moore, J.C.3    Shakespeare, P.G.4    Chen, W.Y.J.5
  • 30
    • 0026605281 scopus 로고
    • Degradation of fibronectin and vitronectin in chronic wound fluid: Analysis by cell blotting, immunoblotting, and cell adhesion assays
    • Grinnell F, Ho C-H, Wysocki AB. Degradation of fibronectin and vitronectin in chronic wound fluid: analysis by cell blotting, immunoblotting, and cell adhesion assays. J Invest Dermatol 1992;98:410-6.
    • (1992) J Invest Dermatol , vol.98 , pp. 410-416
    • Grinnell, F.1    Ho, C.-H.2    Wysocki, A.B.3
  • 31
    • 0028973014 scopus 로고
    • α1-antitrypsin is degraded and non-functional in chronic wounds but intact and functional in acute wounds: The inhibitor protects fibronectin from degradation by chronic wound fluid enzymes
    • Rao CN, Ladin DA, Liu YY, Chilukuri K, Hou ZZ, Woodley DT. α1-antitrypsin is degraded and non-functional in chronic wounds but intact and functional in acute wounds: the inhibitor protects fibronectin from degradation by chronic wound fluid enzymes. J Invest Dermatol 1995;105:572-8.
    • (1995) J Invest Dermatol , vol.105 , pp. 572-578
    • Rao, C.N.1    Ladin, D.A.2    Liu, Y.Y.3    Chilukuri, K.4    Hou, Z.Z.5    Woodley, D.T.6
  • 32
    • 0028981374 scopus 로고
    • Tissue inhibitor of metalloproteinases-1 is decreased and activated gelatinases are increased in chronic wounds
    • Bullen EC, Longaker MT, Updike DL, Benton R, Ladin D, Hou Z, Howard EW. Tissue inhibitor of metalloproteinases-1 is decreased and activated gelatinases are increased in chronic wounds. J Invest Dermatol 1995;104:236-40.
    • (1995) J Invest Dermatol , vol.104 , pp. 236-240
    • Bullen, E.C.1    Longaker, M.T.2    Updike, D.L.3    Benton, R.4    Ladin, D.5    Hou, Z.6    Howard, E.W.7
  • 33
    • 0029938994 scopus 로고    scopus 로고
    • Fibronectin degradation in chronic wounds depends on the relative levels of elastase, α1-proteinase inhibitor, and α2-macroglobulin
    • Grinnell F, Zhu M. Fibronectin degradation in chronic wounds depends on the relative levels of elastase, α1-proteinase inhibitor, and α2-macroglobulin. J Invest Dermatol 1996;106:335-41.
    • (1996) J Invest Dermatol , vol.106 , pp. 335-341
    • Grinnell, F.1    Zhu, M.2
  • 34
    • 0027286585 scopus 로고
    • Tissue and urokinase plasminogen activators in the environs of venous and ischaemic leg ulcers
    • Stacey MC, Burnand KG, Mahmoud-Alexandroni M, Gaffney PJ, Bhogal BS. Tissue and urokinase plasminogen activators in the environs of venous and ischaemic leg ulcers. Br J Surg 1993;80:596-9.
    • (1993) Br J Surg , vol.80 , pp. 596-599
    • Stacey, M.C.1    Burnand, K.G.2    Mahmoud-Alexandroni, M.3    Gaffney, P.J.4    Bhogal, B.S.5
  • 35
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-5.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 36
    • 0018747530 scopus 로고
    • Mapping the extended substrate binding site of cathepsin G and human leukocyte elastase
    • Nakajima K, Powers JC, Ashe BM, Zimmerman M. Mapping the extended substrate binding site of cathepsin G and human leukocyte elastase. J Biol Chem 1979;254:4027-32.
    • (1979) J Biol Chem , vol.254 , pp. 4027-4032
    • Nakajima, K.1    Powers, J.C.2    Ashe, B.M.3    Zimmerman, M.4
  • 37
    • 0024333351 scopus 로고
    • α-Macroglobulins: Structure, shape, and mechanism of proteinase complex formation
    • Sottrup-Jensen L. α-Macroglobulins: structure, shape, and mechanism of proteinase complex formation. J Biol Chem 1989;264:11539-42.
    • (1989) J Biol Chem , vol.264 , pp. 11539-11542
    • Sottrup-Jensen, L.1
  • 38
    • 0015896128 scopus 로고
    • The interaction of alpha 2-macroglobulin with proteinases: Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism
    • Barrett AJ, Starkey PM. The interaction of alpha 2-macroglobulin with proteinases: characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism. Biochem J 1973;133:709-24.
    • (1973) Biochem J , vol.133 , pp. 709-724
    • Barrett, A.J.1    Starkey, P.M.2
  • 39
    • 0024550864 scopus 로고
    • Elastase inhibitor. Characterization of the human elastase inhibitor molecule associated with monocytes, macrophages, and neutrophils
    • Remold-O'Donnell E, Nixon JC, Rose RM. Elastase inhibitor. Characterization of the human elastase inhibitor molecule associated with monocytes, macrophages, and neutrophils. J Exp Med 1989;169:1071-86.
    • (1989) J Exp Med , vol.169 , pp. 1071-1086
    • Remold-O'Donnell, E.1    Nixon, J.C.2    Rose, R.M.3
  • 40
    • 0023677472 scopus 로고
    • Plasminogen activator inhibitors - A review
    • Kruithof EK. Plasminogen activator inhibitors - a review. Enzyme 1988;40:113-21.
    • (1988) Enzyme , vol.40 , pp. 113-121
    • Kruithof, E.K.1
  • 41
    • 0027076834 scopus 로고
    • α2-Macroglobulin, a multifunctional binding protein with targeting characteristics
    • Borth W. α2-Macroglobulin, a multifunctional binding protein with targeting characteristics. FASEB J 1992;6:3345-53.
    • (1992) FASEB J , vol.6 , pp. 3345-3353
    • Borth, W.1
  • 42
    • 0023609221 scopus 로고
    • Effects of growth factors in vivo. I. Cell ingrowth into porous subcutaneous chambers
    • Sprugel KH, McPherson JM, Clowes AW, Ross R. Effects of growth factors in vivo. I. Cell ingrowth into porous subcutaneous chambers. Am J Pathol 1987;129:601-13.
    • (1987) Am J Pathol , vol.129 , pp. 601-613
    • Sprugel, K.H.1    McPherson, J.M.2    Clowes, A.W.3    Ross, R.4
  • 43
    • 0026060696 scopus 로고
    • Reaction of α2-macroglobulin with plasmin increases binding of transforming growth factors-β1 and β2
    • LaMarre J, Wollenberg GK, Gonias SL, Hayes MA. Reaction of α2-macroglobulin with plasmin increases binding of transforming growth factors-β1 and β2. Biochim Biophys Acta 1990;1091: 197-204.
    • (1990) Biochim Biophys Acta , vol.1091 , pp. 197-204
    • LaMarre, J.1    Wollenberg, G.K.2    Gonias, S.L.3    Hayes, M.A.4
  • 44
    • 0024603072 scopus 로고
    • Identification of α2-macroglobulin as a cytokine binding plasma protein. Binding of interleukin-1b to "F" α2-macroglobulin
    • Borth W, Luger TA. Identification of α2-macroglobulin as a cytokine binding plasma protein. Binding of interleukin-1b to "F" α2-macroglobulin. J Biol Chem 1989;264:5818-25.
    • (1989) J Biol Chem , vol.264 , pp. 5818-5825
    • Borth, W.1    Luger, T.A.2
  • 45
    • 0027296736 scopus 로고
    • Activated alpha 2-macroglobulin and transforming growth factor-beta 1 induce a synergistic smooth muscle cell proliferative response
    • Stouffer GA, LaMarre J, Gonias SL, Owens GK. Activated alpha 2-macroglobulin and transforming growth factor-beta 1 induce a synergistic smooth muscle cell proliferative response. J Biol Chem 1993;268:18340-4.
    • (1993) J Biol Chem , vol.268 , pp. 18340-18344
    • Stouffer, G.A.1    LaMarre, J.2    Gonias, S.L.3    Owens, G.K.4
  • 46
    • 0025036481 scopus 로고
    • PDGF-stimulated fibroblast proliferation is enhanced synergistically by receptor-recognized α2-macroglobulin
    • Bonner JC, Badgett A, Osornio-Vargas AR, Hoffman M, Brody AR. PDGF-stimulated fibroblast proliferation is enhanced synergistically by receptor-recognized α2-macroglobulin. J Cell Physiol 1990;145:1-8.
    • (1990) J Cell Physiol , vol.145 , pp. 1-8
    • Bonner, J.C.1    Badgett, A.2    Osornio-Vargas, A.R.3    Hoffman, M.4    Brody, A.R.5
  • 47
    • 0026018925 scopus 로고
    • Identification of α2-macroglobulin as a carrier of human tumor necrosis factor-α: Preferential binding to α2-macroglobulin-plasmin or α2-macroglobulin-methylamine
    • Wollenberg GK, LaMarre J, Rosendal S, Gonias SL, Hayes MA. Identification of α2-macroglobulin as a carrier of human tumor necrosis factor-α: preferential binding to α2-macroglobulin-plasmin or α2-macroglobulin-methylamine. Am J Pathol 1991;138:265-72.
    • (1991) Am J Pathol , vol.138 , pp. 265-272
    • Wollenberg, G.K.1    LaMarre, J.2    Rosendal, S.3    Gonias, S.L.4    Hayes, M.A.5
  • 48
    • 0025374704 scopus 로고
    • α2-Macroglobulin and serum preferentially counteract the mitoinhibitory effect of transforming growth factor-β2 in rat hepatocytes
    • LaMarre J, Wollenberg GK, Gauldie J, Hayes MA. α2-Macroglobulin and serum preferentially counteract the mitoinhibitory effect of transforming growth factor-β2 in rat hepatocytes. Lab Invest 1990;62:545-51.
    • (1990) Lab Invest , vol.62 , pp. 545-551
    • LaMarre, J.1    Wollenberg, G.K.2    Gauldie, J.3    Hayes, M.A.4
  • 51
    • 0027314857 scopus 로고
    • The treatment of chronic nonhealing wounds using autologous platelet-derived growth factors
    • Ganio C, Tenewitz FE, Wilson RC, Moyles BG. The treatment of chronic nonhealing wounds using autologous platelet-derived growth factors. J Foot Ankle Surg 1993;32:263-8.
    • (1993) J Foot Ankle Surg , vol.32 , pp. 263-268
    • Ganio, C.1    Tenewitz, F.E.2    Wilson, R.C.3    Moyles, B.G.4
  • 53
    • 0038400786 scopus 로고
    • Growth factors: Status and expectations
    • Leaper DJ, editor. Amsterdam: Medicom Europe BV
    • Falanga V. Growth factors: status and expectations. In: Leaper DJ, editor. International Symposium on Wound Repair. Amsterdam: Medicom Europe BV, 1991:87-93.
    • (1991) International Symposium on Wound Repair , pp. 87-93
    • Falanga, V.1
  • 54
    • 0026595966 scopus 로고
    • Platelet-derived growth factor BB for the treatment of chronic pressure ulcers
    • Robson MC, Phillips LG, Thomason A, Robson LE, Pierce GF. Platelet-derived growth factor BB for the treatment of chronic pressure ulcers. Lancet 1992;339:23-5.
    • (1992) Lancet , vol.339 , pp. 23-25
    • Robson, M.C.1    Phillips, L.G.2    Thomason, A.3    Robson, L.E.4    Pierce, G.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.