CRHR1 mediates p53 transcription induced by high altitude hypoxia through ERK 1/2 signaling in rat hepatic cells

Peptides

Volumn 44, Issue , 2013, Pages 8-14

  Zhao, Yang ^a,b   Wang, Ming Yang ^a,b   Hao, Ke ^a,b   Chen, Xue Qun ^a,b,c   Du, Ji Zeng ^a,b,c  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b BEIJING HOSPITAL   (China)

^c Key Laboratory of Neuroscience   (China)

Author keywords

Corticotropin releasing hormone; Corticotropin releasing hormone receptor 1; ERK; Hypoxia p53

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; BUTYL[2,5 DIMETHYL 7 (2,4,6 TRIMETHYLPHENYL) 7H PYRROLO[2,3 D]PYRIMIDIN 4 YL]ETHYLAMINE; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAX; PROTEIN P21; PROTEIN P53;

ALTITUDE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL HYPOXIA; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; LIVER CELL; LIVER ISCHEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; TRANSACTIVATION; UPREGULATION;

ALTITUDE; ANIMALS; ANOXIA; CELL HYPOXIA; CELL LINE; HEPATOCYTES; LIVER; MALE; MAP KINASE SIGNALING SYSTEM; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEIN P53;

RATTUS;

EID: 84875918416     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2013.03.023     Document Type: Article

References (48)

1. C. Asker, and K.G. Wiman Selivanova G. p53-induced apoptosis as a safeguard against cancer Biochem Biophys Res Commun 265 1999 1 6
2. S.K. Basu, R. Malik, C.J. Huggins, S. Lee, T. Sebastian, and K. Sakchaisri 3'UTR elements inhibit Ras-induced C/EBPbeta post-translational activation and senescence in tumour cells EMBO J 30 2011 3714 3728
3. K. Boggs, and D. Reisman Increased p53 transcription prior to DNA synthesis is regulated through a novel regulatory element within the p53 promoter Oncogene 25 2006 555 565 (Pubitemid 43164466)
4. J.C. Bourdon, V. Deguin-Chambon, J.C. Lelong, P. Dessen, P. May, and B. Debuire Further characterisation of the p53 responsive element - identification of new candidate genes for trans-activation by p53 Oncogene 14 1997 85 94 (Pubitemid 27042958)
5. V. Budhram-Mahadeo, P.J. Morris, M.D. Smith, C.A. Midgley, and L.M. Boxer Latchman DS. p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor J Biol Chem 274 1999 15237 15244
6. C.E. Canman, D.S. Lim, K.A. Cimprich, Y. Taya, K. Tamai, and K. Sakaguchi Activation of the ATM kinase by ionizing radiation and phosphorylation of p53 Science 281 1998 1677 1679 (Pubitemid 28435584)
7. I. Charalampopoulos, A. Androulidaki, V. Minas, E. Chatzaki, C. Tsatsanis, and G. Notas Neuropeptide urocortin and its receptors are expressed in rat Kupffer cells Neuroendocrinology 84 2006 49 57 (Pubitemid 44973687)
8. X. Chen, L.J. Ko, and L. Jayaraman Prives C. p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells Genes Dev 10 1996 2438 2451 (Pubitemid 26341879)
9. X.Q. Chen, F.P. Kong, Y. Zhao, and J.Z. Du High-altitude hypoxia induces disorders of the brain-endocrine-immune network through activation of corticotropin-releasing factor and its type-1 Zhongguo Yingyong Shenglixue Zazhi 28 2012 481 487
10. X.Q. Chen, S.J. Wang, J.Z. Du, and X.C. Chen Diversities in hepatic HIF-1, IGF-I/IGFBP-1, LDH/ICD, and their mRNA expressions induced by CoCl(2) in Qinghai-Tibetan plateau mammals and sea level mice Am J Physiol Regul Integr Comp Physiol 292 2007 R516 R526
11. Z. Chen, and J.Z. Du Hypoxia effects on hypothalamic corticotropin- releasing hormone and anterior pituitary cAMP Zhongguo Yao Li Xue Bao 17 1996 489 492 (Pubitemid 26371668)
12. S. Chitayat, and C.H. Arrowsmith Four p(53)s in a pod Nat Struct Mol Biol 17 2010 390 391
13. D.M. Cortez, M.D. Feldman, S. Mummidi, A.J. Valente, B. Steffensen, and M. Vincenti IL-17 stimulates MMP-1 expression in primary human cardiac fibroblasts via p38 MAPK- and ERK1/2-dependent C/EBP-beta, NF-kappaB, and AP-1 activation Am J Physiol Heart Circ Physiol 293 2007 H3356 H3365
14. W.S. el-Deiry, T. Tokino, V.E. Velculescu, D.B. Levy, R. Parsons, and J.M. Trent WAF1, a potential mediator of p53 tumor suppression Cell 75 1993 817 825 (Pubitemid 23346378)
15. S.L. Gibson, R.S. Bindra, and P.M. Glazer Hypoxia-induced phosphorylation of Chk2 in an ataxia telangiectasia mutated-dependent manner Cancer Res 65 2005 10734 10741 (Pubitemid 41713341)
16. T.G. Graeber, C. Osmanian, T. Jacks, D.E. Housman, C.J. Koch, and S.W. Lowe Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours Nature 379 1996 88 91 (Pubitemid 26008141)
17. E.M. Hammond, and A.J. Giaccia The role of ATM and ATR in the cellular response to hypoxia and re-oxygenation DNA Repair (Amst) 3 2004 1117 1122 (Pubitemid 38997955)
18. E.M. Hammond, and A.J. Giaccia The role of p53 in hypoxia-induced apoptosis Biochem Biophys Res Commun 331 2005 718 725 (Pubitemid 40615503)
19. E.M. Hammond, D.J. Mandell, A. Salim, A.J. Krieg, T.M. Johnson, and H.A. Shirazi Genome-wide analysis of p53 under hypoxic conditions Mol Cell Biol 26 2006 3492 3504
20. H. Hsuchou, A.J. Kastin, X. Wu, H. Tu, and W. Pan Corticotropin-releasing hormone receptor-1 in cerebral microvessels changes during development and influences urocortin transport across the blood-brain barrier Endocrinology 151 2010 1221 1227
21. M.J. Kang, S.M. Jung, M.J. Kim, J.H. Bae, H.B. Kim, and J.Y. Kim DNA-dependent protein kinase is involved in heat shock protein-mediated accumulation of hypoxia-inducible factor-1alpha in hypoxic preconditioned HepG2 cells FEBS J 275 2008 5969 5981
22. T.K. Kim In vitro transcriptional activation of p21 promoter by p53 Biochem Biophys Res Commun 234 1997 300 302 (Pubitemid 27243895)
23. M. Kitayner, H. Rozenberg, R. Rohs, O. Suad, D. Rabinovich, and B. Honig Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs Nat Struct Mol Biol 17 2010 423 429
24. C. Koumenis, R. Alarcon, E. Hammond, P. Sutphin, W. Hoffman, and M. Murphy Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation Mol Cell Biol 21 2001 1297 1310 (Pubitemid 32114977)
25. K. Krause, M. Wasner, W. Reinhard, U. Haugwitz, C.L. Dohna, and J. Mossner The tumour suppressor protein p53 can repress transcription of cyclin B Nucleic Acids Res 28 2000 4410 4418
26. J.P. Kruse, and W. Gu Modes of p53 regulation Cell 137 2009 609 622
27. Q.T. Le, N.C. Denko, and A.J. Giaccia Hypoxic gene expression and metastasis Cancer Metastasis Rev 23 2004 293 310 (Pubitemid 38881813)
28. H.G. Lee, H. Minematsu, K.O. Kim, A.B. Celil Aydemir, M.J. Shin, and S.A. Nizami Actin and ERK1/2-CEBPbeta signaling mediates phagocytosis-induced innate immune response of osteoprogenitor cells Biomaterials 32 2011 9197 9206
29. J.I. Leu, M.A. Crissey, and R. Taub Massive hepatic apoptosis associated with TGF-beta1 activation after Fas ligand treatment of IGF binding protein-1-deficient mice J Clin Invest 111 2003 129 139 (Pubitemid 36134856)
30. T. Miyashita, and J.C. Reed Tumor suppressor p53 is a direct transcriptional activator of the human bax gene Cell 80 1995 293 299
31. Y. Pan, P.R. Oprysko, A.M. Asham, C.J. Koch, and M.C. Simon p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment Oncogene 23 2004 4975 4983 (Pubitemid 38938730)
32. K.A. Paschos, C. Charsou, T.C. Constantinidis, S. Anagnostoulis, M. Lambropoulou, and F. Papachristou Corticotropin-releasing hormone receptors mediate opposing effects in cholestasis-induced liver cell apoptosis Endocrinology 151 2010 1704 1712
33. D.N. Patel, C.A. King, S.R. Bailey, J.W. Holt, K. Venkatachalam, and A. Agrawal Interleukin-17 stimulates C-reactive protein expression in hepatocytes and smooth muscle cells via p38 MAPK and ERK1/2-dependent NF-kappaB and C/EBPbeta activation J Biol Chem 282 2007 27229 27238 (Pubitemid 47501976)
34. D. Refojo, C. Echenique, M.B. Muller, J.M. Reul, J.M. Deussing, and W. Wurst Corticotropin-releasing hormone activates ERK1/2 MAPK in specific brain areas Proc Natl Acad Sci USA 102 2005 6183 6188 (Pubitemid 40594275)
35. K. Sakaguchi, J.E. Herrera, S. Saito, T. Miki, M. Bustin, and A. Vassilev DNA damage activates p53 through a phosphorylation-acetylation cascade Genes Dev 12 1998 2831 2841 (Pubitemid 28440142)
36. S. Sengupta, and B. Wasylyk Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2 Genes Dev 15 2001 2367 2380 (Pubitemid 32899741)
37. S.Y. Shieh, M. Ikeda, Y. Taya, and C. Prives DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2 Cell 91 1997 325 334 (Pubitemid 27467963)
38. S. Silberstein, A.M. Vogl, D. Refojo, S.A. Senin, W. Wurst, and F. Holsboer Amygdaloid pERK1/2 in corticotropin-releasing hormone overexpressing mice under basal and acute stress conditions Neuroscience 159 2009 610 617
39. G. Tringali, M.C. Greco, L. Lisi, G. Pozzoli, and P. Navarra Cortistatin modulates the expression and release of corticotrophin releasing hormone in rat brain. Comparison with somatostatin and octreotide Peptides 34 2012 353 359
40. H. Tu, A.J. Kastin, and W. Pan Corticotropin-releasing hormone receptor (CRHR)1 and CRHR2 are both trafficking and signaling receptors for urocortin Mol Endocrinol 21 2007 700 711
41. W. Vale, J. Spiess, C. Rivier, and J. Rivier Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin Science 213 1981 1394 1397 (Pubitemid 12243637)
42. G.L. Wang, and G.L. Semenza Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia J Biol Chem 268 1993 21513 21518 (Pubitemid 23320639)
43. G.L. Wang, and G.L. Semenza General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia Proc Natl Acad Sci USA 90 1993 4304 4308 (Pubitemid 23134215)
44. T.Y. Wang, X.Q. Chen, J.Z. Du, N.Y. Xu, C.B. Wei, and W.W. Vale Corticotropin-releasing factor receptor type 1 and 2 mRNA expression in the rat anterior pituitary is modulated by intermittent hypoxia, cold and restraint Neuroscience 128 2004 111 119 (Pubitemid 39140684)
45. J.F. Xu, X.Q. Chen, J.Z. Du, and T.Y. Wang CRF receptor type 1 mediates continual hypoxia-induced CRF peptide and CRF mRNA expression increase in hypothalamic PVN of rats Peptides 26 2005 639 646
46. Y. Yang, H. Park, T.S. Kim, S.I. Bang, and D. Cho Enhancement of cell migration by corticotropin-releasing hormone through ERK1/2 pathway in murine melanoma cell line, B16F10 Exp Dermatol 16 2007 22 27 (Pubitemid 44890347)
47. L. Zhao, D.Q. Peng, J. Zhang, J.Q. Song, X. Teng, and Y.R. Yu Extracellular signal-regulated kinase 1/2 activation is involved in intermedin1-53 attenuating myocardial oxidative stress injury induced by ischemia/reperfusion Peptides 33 2012 329 335
48. Y. Zhao, X.Q. Chen, and J.Z. Du Cellular adaptation to hypoxia and p53 transcription regulation J Zhejiang Univ Sci B 10 2009 404 410