Actin and ERK1/2-CEBPβ signaling mediates phagocytosis-induced innate immune response of osteoprogenitor cells

Biomaterials

Volumn 32, Issue 35, 2011, Pages 9197-9206

  Lee, Heon Goo ^a,b   Minematsu, Hiroshi ^a   Kim, Kyung Ok ^a   Celil Aydemir, Ayse B ^a   Shin, Mike J ^a   Nizami, Saqib A ^a   Chung, Kook Jin ^a,c   Hsu, Anny C ^a   Jacobs, Christopher R ^b   Lee, Francis Youngin ^a  

^a Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

^b Fu Foundation School of Engineering and Applied Science   (United States)

^c Hallym University   (South Korea)

Author keywords

Actin; Cox2; ERK; IL6; Particle

Indexed keywords

ACTIN; ARTHOPLASTIES; ASEPTIC LOOSENING; BONE FORMATION; BONE IMPLANT; BONE REGENERATION; BONE-IMPLANT INTERFACES; CELLULAR MECHANISMS; COX2; ERK; IL6; IN-VITRO; IN-VIVO; INFLAMMATORY GENES; INFLAMMATORY RESPONSE; INNATE IMMUNE RESPONSE; INTRACELLULAR SIGNALING; METAL WEAR; OSTEOCLASTOGENESIS; OSTEOINTEGRATION; OSTEOLYSIS; OSTEOPROGENITOR CELLS; OSTEOPROGENITORS; POTENT INHIBITOR; THERAPEUTIC TARGETS; WEAR PARTICLES;

ANTIGEN-ANTIBODY REACTIONS; BONE; ENZYME ACTIVITY; GENE EXPRESSION; MACROPHAGES; PARTICLES (PARTICULATE MATTER); PATHOLOGY;

PROTEINS;

ACTIN; CCAAT ENHANCER BINDING PROTEIN BETA; CYCLOOXYGENASE 2; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SELUMETINIB; TITANIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ATTENUATION; BONE CELL; CONTROLLED STUDY; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INNATE IMMUNITY; INTRACELLULAR SIGNALING; MACROPHAGE; MALE; MOUSE; NONHUMAN; OSTEOCLASTOGENESIS; OSTEOLYSIS; OSTEOPROGENITOR CELL; PHAGOCYTOSIS; PRIORITY JOURNAL; STEM CELL;

ACTINS; ADHESIVENESS; ANIMALS; BENZIMIDAZOLES; BONE AND BONES; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CYCLOOXYGENASE 2; CYTOCHALASIN D; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY, INNATE; INFLAMMATION; INTERLEUKIN-6; MAP KINASE SIGNALING SYSTEM; MICE; MODELS, BIOLOGICAL; OSTEOGENESIS; OSTEOLYSIS; PHAGOCYTOSIS; PROTEIN KINASE INHIBITORS; SIGNAL TRANSDUCTION; SKULL; STEM CELLS; TIME FACTORS; TITANIUM;

EID: 80053602775     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.08.059     Document Type: Article

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