Extending nature's leads: The anticancer agent ellipticine

Current Medicinal Chemistry - Anti-Cancer Agents

Volumn 4, Issue 2, 2004, Pages 149-172

  Garbett, Nichola C ^a   Graves, David E ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Anticancer; Bioactivation; DNA binding; Drug design; Ellipticine; Natural product; Plant alkaloid; Topoisomerase II

Indexed keywords

2 (DIETHYLAMINO 2 ETHYL) 9 HYDROXYELLIPTICINE; 2 ETHYL 9 HYDROXYELLIPTICINE; 2 ETHYLELLIPTICINE; 2 METHYL 6 METHYL 9 HYDOXYELLIPTICINE; 2 METHYL 6 METHYLELLIPTICINE; 2 METHYLELLIPTICINE; 6 ALKYLELLIPTICINE; 6 METHYLELLIPTICINE; 9 AMINOELLIPTICINE; 9 HYDROXYELLIPTICINE; 9 METHOXYELLIPTICINE LACTATE; ANTINEOPLASTIC AGENT; DISTAMYCIN A; DITERCALINIUM; DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; ELLIPTICINE; ELLIPTICINE DERIVATIVE; ELLIPTINIUM; ELLIPTINIUM ACETATE; ETOPOSIDE; INTERCALATING AGENT; NITROGEN DERIVATIVE; NUCLEIC ACID; PACLITAXEL; PAZELLIPTINE; POLYCYCLIC HYDROCARBON; TELOMERASE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANOREXIA; ANTINEOPLASTIC ACTIVITY; APOCYNACEAE; AUSTRALIA; BINDING AFFINITY; BONE MARROW TOXICITY; CARDIOVASCULAR DISEASE; CHILL; CLINICAL TRIAL; DNA BINDING; DRUG DESIGN; DRUG ELIMINATION; DRUG INHIBITION; DRUG ISOLATION; DRUG MECHANISM; DRUG METABOLISM; DRUG RESEARCH; DRUG SYNTHESIS; DRUG TISSUE LEVEL; ENZYME ACTIVITY; ENZYME MODIFICATION; FEVER; HEMOLYTIC ANEMIA; HUMAN; HYPERTHERMIA; HYPOTENSION; INTRACRANIAL TUMOR; LEUKEMIA; LIPOPHILICITY; NAUSEA; NEPHROTOXICITY; NEUROTOXICITY; NONHUMAN; RESPIRATION DEPRESSION; REVIEW; STRUCTURE ACTIVITY RELATION; TREE; VOMITING; XEROSTOMIA;

ANIMALS; ANTINEOPLASTIC AGENTS; APOCYNACEAE; ELLIPTICINES; HUMANS; NEOPLASMS; PHYTOTHERAPY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 1642565147     PISSN: 15680118     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568011043482070     Document Type: Review

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