A global comparability approach for biosimilar monoclonal antibodies using LC-tandem MS based proteomics

Journal of Pharmaceutical and Biomedical Analysis

Volumn 80, Issue , 2013, Pages 126-135

  Chen, Shun Li ^a   Wu, Shiaw Lin ^b   Huang, Li Juan ^a   Huang, Jia Bao ^c   Chen, Shu Hui ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NORTHEASTERN UNIVERSITY   (United States)

^c ScinoPharm Taiwan Ltd   (Taiwan)

Author keywords

Biosimilar; Comparability study; LC MS; Proteomics; Trastuzumab

Indexed keywords

DISULFIDE; TRASTUZUMAB;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL MODIFICATION; DEAMINATION; DEHYDRATION; DISSOCIATION; ELECTRON TRANSPORT; GLYCOSYLATION; K CLIPPING; LIQUID CHROMATOGRAPHY; OXIDATION; PRIORITY JOURNAL; PROTEOMICS; TANDEM MASS SPECTROMETRY;

ANIMALS; ANTIBODIES, MONOCLONAL, HUMANIZED; BIOSIMILAR PHARMACEUTICALS; CHO CELLS; CHROMATOGRAPHY, LIQUID; CRICETINAE; CRICETULUS; PEPTIDE MAPPING; PROTEOMICS; TANDEM MASS SPECTROMETRY;

EID: 84875844715     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2013.02.040     Document Type: Article

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