Rapid assessment of molecular similarity between a candidate biosimilar and an innovator monoclonal antibody using complementary LC-MS methods

BioPharm International

Volumn 23, Issue 8 SUPPL., 2010, Pages 16-21

  Gilar, Martin ^a   Xie, Hongwei ^a   Chakraborty, Asish ^a   Ahn, Joomi ^a   Yu, Ying Qing ^a   Dakshinamoorthy, Deepalakshmi P ^a,b   Chen, Weibin ^a   Skilton, St John ^a   Mazzeo, Jeffery R ^a  

^a WATERS CORPORATION   (United States)

^b SGS India Pvt Ltd   (India)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G1 ANTIBODY; TRASTUZUMAB;

ACCURACY; AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; INTERMETHOD COMPARISON; MASS SPECTROMETRY; PEPTIDE MAPPING; PRODUCT DEVELOPMENT; PROTEIN DEGRADATION; PROTEIN DENATURATION; PROTEIN GLYCOSYLATION; PROTEIN VARIANT; QUALITY CONTROL; SEQUENCE HOMOLOGY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 78650489767     PISSN: 1542166X     EISSN: None     Source Type: Trade Journal    
DOI: None     Document Type: Article

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