메뉴 건너뛰기




Volumn 5, Issue 4, 2013, Pages 640-653

Actin filament dynamics impacts keratinocyte stem cell maintenance

Author keywords

Actin filaments; Clonal conversion; EGF; EGFR signalling; Keratinocyte stem cells

Indexed keywords

EPIDERMAL GROWTH FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; RAC1 PROTEIN;

EID: 84875800732     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201201839     Document Type: Article
Times cited : (45)

References (68)
  • 1
    • 78149353346 scopus 로고    scopus 로고
    • Rho-kinase/ROCK: a key regulator of the cytoskeleton and cell polarity
    • Amano M, Nakayama M, Kaibuchi K (2010) Rho-kinase/ROCK: a key regulator of the cytoskeleton and cell polarity. Cytoskeleton 67: 545-554
    • (2010) Cytoskeleton , vol.67 , pp. 545-554
    • Amano, M.1    Nakayama, M.2    Kaibuchi, K.3
  • 2
    • 0011478490 scopus 로고
    • Three clonal types of keratinocyte with different capacities for multiplication
    • Barrandon Y, Green H (1987a) Three clonal types of keratinocyte with different capacities for multiplication. Proc Natl Acad Sci USA 84: 2302-2306
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 2302-2306
    • Barrandon, Y.1    Green, H.2
  • 3
    • 0023624729 scopus 로고
    • Cell migration is essential for sustained growth of keratinocyte colonies: the roles of transforming growth factor-alpha and epidermal growth factor
    • Barrandon Y, Green H (1987b) Cell migration is essential for sustained growth of keratinocyte colonies: the roles of transforming growth factor-alpha and epidermal growth factor. Cell 50: 1131-1137
    • (1987) Cell , vol.50 , pp. 1131-1137
    • Barrandon, Y.1    Green, H.2
  • 4
    • 0024409168 scopus 로고
    • Restoration of growth potential in paraclones of human keratinocytes by a viral oncogene
    • Barrandon Y, Morgan JR, Mulligan RC, Green H (1989) Restoration of growth potential in paraclones of human keratinocytes by a viral oncogene. Proc Natl Acad Sci USA 86: 4102-4106
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 4102-4106
    • Barrandon, Y.1    Morgan, J.R.2    Mulligan, R.C.3    Green, H.4
  • 7
    • 80155142474 scopus 로고    scopus 로고
    • Rapamycin passes the torch: a new generation of mTOR inhibitors
    • Benjamin D, Colombi M, Moroi C, Hall MH (2011) Rapamycin passes the torch: a new generation of mTOR inhibitors. Nat Rev Drug Discov 10: 868-880
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 868-880
    • Benjamin, D.1    Colombi, M.2    Moroi, C.3    Hall, M.H.4
  • 8
    • 23244452354 scopus 로고    scopus 로고
    • Stem cell depletion through epidermal deletion of Rac1
    • Benitah SA, Frye M, Glogauer M, Watt FM (2005) Stem cell depletion through epidermal deletion of Rac1. Science 309: 933-935
    • (2005) Science , vol.309 , pp. 933-935
    • Benitah, S.A.1    Frye, M.2    Glogauer, M.3    Watt, F.M.4
  • 9
    • 60749125436 scopus 로고    scopus 로고
    • Epidermal homeostasis: a balancing act of stem cells in the skin
    • Blanpain C, Fuchs E (2009) Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol 10: 207-217
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 207-217
    • Blanpain, C.1    Fuchs, E.2
  • 10
    • 25444466556 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase signaling to Akt promotes keratinocyte differentiation versus death
    • Calautti E, Li J, Saoncella S, Brissette JL, Goetinck PF (2005) Phosphoinositide 3-kinase signaling to Akt promotes keratinocyte differentiation versus death. J Biol Chem 280: 32856-32865
    • (2005) J Biol Chem , vol.280 , pp. 32856-32865
    • Calautti, E.1    Li, J.2    Saoncella, S.3    Brissette, J.L.4    Goetinck, P.F.5
  • 11
    • 0035020950 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase signalling pathways
    • Cantrell DA (2001) Phosphoinositide 3-kinase signalling pathways. J Cell Sci 114: 1439-1445
    • (2001) J Cell Sci , vol.114 , pp. 1439-1445
    • Cantrell, D.A.1
  • 12
    • 77954975403 scopus 로고    scopus 로고
    • Human keratinocytes are efficiently immortalized by a Rho kinase inhibitor
    • Chapman S, Liu X, Meyers C, Schlegel R, McBride AA (2010) Human keratinocytes are efficiently immortalized by a Rho kinase inhibitor. J Clin Invest 120: 2619-2626
    • (2010) J Clin Invest , vol.120 , pp. 2619-2626
    • Chapman, S.1    Liu, X.2    Meyers, C.3    Schlegel, R.4    McBride, A.A.5
  • 15
    • 77954243855 scopus 로고    scopus 로고
    • Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions
    • Connelly JT, Gautrot JE, Trappmann B, Tan DW, Donati G, Huck WT, Watt FM (2010) Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions. Nat Cell Biol 12: 711-718
    • (2010) Nat Cell Biol , vol.12 , pp. 711-718
    • Connelly, J.T.1    Gautrot, J.E.2    Trappmann, B.3    Tan, D.W.4    Donati, G.5    Huck, W.T.6    Watt, F.M.7
  • 16
    • 33645764295 scopus 로고    scopus 로고
    • Regeneration of squamous epithelia from stem cells of cultured grafts
    • De Luca M, Pellegrini G, Green H (2006) Regeneration of squamous epithelia from stem cells of cultured grafts. Regen Med 1: 45-57
    • (2006) Regen Med , vol.1 , pp. 45-57
    • De Luca, M.1    Pellegrini, G.2    Green, H.3
  • 17
    • 0034729189 scopus 로고    scopus 로고
    • Downregulation of 14-3-3sigma prevents clonal evolution and leads to immortalization of primary human keratinocytes
    • Dellambra E, Golisano O, Bondanza S, Siviero E, Lacal P, Molinari M, D'Atri S, De Luca M (2000) Downregulation of 14-3-3sigma prevents clonal evolution and leads to immortalization of primary human keratinocytes. J Cell Biol 149: 1117-1130
    • (2000) J Cell Biol , vol.149 , pp. 1117-1130
    • Dellambra, E.1    Golisano, O.2    Bondanza, S.3    Siviero, E.4    Lacal, P.5    Molinari, M.6    D'Atri, S.7    De Luca, M.8
  • 18
    • 0023619671 scopus 로고
    • Molecular and cytogenetic analysis of immortalized human primary keratinocytes obtained after transfection with human papillomavirus type 16 DNA
    • Dürst M, Dzarlieva-Petrusevska RT, Boukamp P, Fusenig NE, Gissmann L (1987) Molecular and cytogenetic analysis of immortalized human primary keratinocytes obtained after transfection with human papillomavirus type 16 DNA. Oncogene 1: 251-256
    • (1987) Oncogene , vol.1 , pp. 251-256
    • Dürst, M.1    Dzarlieva-Petrusevska, R.T.2    Boukamp, P.3    Fusenig, N.E.4    Gissmann, L.5
  • 19
  • 20
    • 80053319997 scopus 로고    scopus 로고
    • Dynamics of actomyosin contractile activity during epithelial morphogenesis
    • Gorfinkiel N, Blanchard GB (2011) Dynamics of actomyosin contractile activity during epithelial morphogenesis. Curr Opin Cell Biol 23: 531-539
    • (2011) Curr Opin Cell Biol , vol.23 , pp. 531-539
    • Gorfinkiel, N.1    Blanchard, G.B.2
  • 22
    • 22744450061 scopus 로고    scopus 로고
    • ADAM-mediated ectodomain shedding of HB-EGF in receptor cross-talk
    • Higashiyama S, Nanba D (2005) ADAM-mediated ectodomain shedding of HB-EGF in receptor cross-talk. Biochim Biophys Acta 1751: 110-117
    • (2005) Biochim Biophys Acta , vol.1751 , pp. 110-117
    • Higashiyama, S.1    Nanba, D.2
  • 23
    • 84861535107 scopus 로고    scopus 로고
    • mTOR: the master regulator
    • Hosking R (2012) mTOR: the master regulator. Cell 149: 955-957
    • (2012) Cell , vol.149 , pp. 955-957
    • Hosking, R.1
  • 26
    • 61849125771 scopus 로고    scopus 로고
    • PI3-kinase-dependent activation of apoptotic machinery occurs on commitment of epidermal keratinocytes to terminal differentiation
    • Janes SM, Ofstad TA, Campbell DH, Eddaoudi A, Warnes G, Davies D, Watt FM (2009) PI3-kinase-dependent activation of apoptotic machinery occurs on commitment of epidermal keratinocytes to terminal differentiation. Cell Res 19: 328-339
    • (2009) Cell Res , vol.19 , pp. 328-339
    • Janes, S.M.1    Ofstad, T.A.2    Campbell, D.H.3    Eddaoudi, A.4    Warnes, G.5    Davies, D.6    Watt, F.M.7
  • 27
    • 0030912133 scopus 로고    scopus 로고
    • Rapamycin (sirolimus) inhibits proliferating cell nuclear antigen expression and blocks cell cycle in the G1 phase in human keratinocyte stem cells
    • Javier AF, Bata-Csorgo Z, Ellis CN, Kang S, Voorhees JJ, Cooper KD (1997) Rapamycin (sirolimus) inhibits proliferating cell nuclear antigen expression and blocks cell cycle in the G1 phase in human keratinocyte stem cells. J Clin Invest 99: 2094-2099
    • (1997) J Clin Invest , vol.99 , pp. 2094-2099
    • Javier, A.F.1    Bata-Csorgo, Z.2    Ellis, C.N.3    Kang, S.4    Voorhees, J.J.5    Cooper, K.D.6
  • 28
    • 33747047561 scopus 로고    scopus 로고
    • Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence
    • Jensen KB, Watt FM (2006) Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence. Proc Natl Acad Sci USA 103: 11958-11963
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 11958-11963
    • Jensen, K.B.1    Watt, F.M.2
  • 30
    • 34848885826 scopus 로고    scopus 로고
    • Sic transit gloria: farewell to the epidermal transit amplifying cell
    • Jones PH, Simons BD, Watt FM (2007) Sic transit gloria: farewell to the epidermal transit amplifying cell? Cell Stem Cell 1: 371-381
    • (2007) Cell Stem Cell , vol.1 , pp. 371-381
    • Jones, P.H.1    Simons, B.D.2    Watt, F.M.3
  • 33
    • 0034614606 scopus 로고    scopus 로고
    • Akt protein kinase inhibits Rac1-GTP binding through phosphorylation at serine 71 of Rac1
    • Kwon T, Kwon DY, Chun J, Kim JH, Kang SS (2000) Akt protein kinase inhibits Rac1-GTP binding through phosphorylation at serine 71 of Rac1. J Biol Chem 275: 423-428
    • (2000) J Biol Chem , vol.275 , pp. 423-428
    • Kwon, T.1    Kwon, D.Y.2    Chun, J.3    Kim, J.H.4    Kang, S.S.5
  • 34
    • 84859778293 scopus 로고    scopus 로고
    • mTOR signaling in growth control and disease
    • Laplante M, Sabatini DM (2012) mTOR signaling in growth control and disease. Cell 149: 274-293
    • (2012) Cell , vol.149 , pp. 274-293
    • Laplante, M.1    Sabatini, D.M.2
  • 36
    • 84856516992 scopus 로고    scopus 로고
    • Biochemical regulation of contractility: spatial control and dynamics
    • Levayer R, Lecuit T (2012) Biochemical regulation of contractility: spatial control and dynamics. Trends Cell Biol 22: 61-81
    • (2012) Trends Cell Biol , vol.22 , pp. 61-81
    • Levayer, R.1    Lecuit, T.2
  • 37
    • 0011844545 scopus 로고
    • The reorganization of microtubules and microfilaments in differentiating keratinocytes
    • Lewis L, Barrandon Y, Green H, Albrecht-Buehler G (1987) The reorganization of microtubules and microfilaments in differentiating keratinocytes. Differentiation 36: 228-233
    • (1987) Differentiation , vol.36 , pp. 228-233
    • Lewis, L.1    Barrandon, Y.2    Green, H.3    Albrecht-Buehler, G.4
  • 38
    • 78649956469 scopus 로고    scopus 로고
    • mTORC2 regulates neutrophil chemotaxis in a cAMP- and RhoA-dependent fashion
    • Liu L, Das S, Losert W, Parent CA (2010) mTORC2 regulates neutrophil chemotaxis in a cAMP- and RhoA-dependent fashion. Dev Cell 19: 845-857
    • (2010) Dev Cell , vol.19 , pp. 845-857
    • Liu, L.1    Das, S.2    Losert, W.3    Parent, C.A.4
  • 39
    • 67349217986 scopus 로고    scopus 로고
    • Molecular mechanisms of mTOR-mediated translational control
    • Ma XM, Blenis J (2009) Molecular mechanisms of mTOR-mediated translational control. Nat Rev Mol Cell Biol 10: 307-318
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 307-318
    • Ma, X.M.1    Blenis, J.2
  • 40
    • 82455210774 scopus 로고    scopus 로고
    • Tuning cell shape change with contractile ratchets
    • Mason FM, Martin AC (2011) Tuning cell shape change with contractile ratchets. Curr Opin Genet Dev 21: 671-679
    • (2011) Curr Opin Genet Dev , vol.21 , pp. 671-679
    • Mason, F.M.1    Martin, A.C.2
  • 42
    • 1942540793 scopus 로고    scopus 로고
    • ERK activation propagates in epithelial cell sheets and regulates their migration during wound healing
    • Matsubayashi Y, Ebisuya M, Honjoh S, Nishida E (2004) ERK activation propagates in epithelial cell sheets and regulates their migration during wound healing. Curr Biol 14: 731-735
    • (2004) Curr Biol , vol.14 , pp. 731-735
    • Matsubayashi, Y.1    Ebisuya, M.2    Honjoh, S.3    Nishida, E.4
  • 46
    • 0033549558 scopus 로고    scopus 로고
    • Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner
    • Nguyen DH, Catling AD, Webb DJ, Sankovic M, Walker LA, Somlyo AV, Weber MJ, Gonias SL (1999) Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner. J Cell Biol 146: 149-164
    • (1999) J Cell Biol , vol.146 , pp. 149-164
    • Nguyen, D.H.1    Catling, A.D.2    Webb, D.J.3    Sankovic, M.4    Walker, L.A.5    Somlyo, A.V.6    Weber, M.J.7    Gonias, S.L.8
  • 47
    • 39049114765 scopus 로고    scopus 로고
    • The inhibition of the expression of the small GTPase Rac1 induces differentiation with no effect on cell proliferation in growing human adult keratinocytes
    • Nikolova E, Mitev V, Minner F, Deroanne CF, Poumay Y (2008) The inhibition of the expression of the small GTPase Rac1 induces differentiation with no effect on cell proliferation in growing human adult keratinocytes. J Cell Biochem 103: 857-864
    • (2008) J Cell Biochem , vol.103 , pp. 857-864
    • Nikolova, E.1    Mitev, V.2    Minner, F.3    Deroanne, C.F.4    Poumay, Y.5
  • 48
    • 33750472978 scopus 로고    scopus 로고
    • Regulation of epidermal homeostasis and repair by phopshoinositide 3-kinase
    • Pankow S, Bamberger C, Klippel A, Werner S (2006) Regulation of epidermal homeostasis and repair by phopshoinositide 3-kinase. J Cell Sci 119: 4033-4046
    • (2006) J Cell Sci , vol.119 , pp. 4033-4046
    • Pankow, S.1    Bamberger, C.2    Klippel, A.3    Werner, S.4
  • 49
    • 43749094998 scopus 로고    scopus 로고
    • The epidermal growth factor receptor system in skin repair and inflammation
    • Pastore S, Mascia F, Mariani V, Girolomoni G (2008) The epidermal growth factor receptor system in skin repair and inflammation. J Invest Dermatol 128: 1365-1374
    • (2008) J Invest Dermatol , vol.128 , pp. 1365-1374
    • Pastore, S.1    Mascia, F.2    Mariani, V.3    Girolomoni, G.4
  • 50
    • 0033610284 scopus 로고    scopus 로고
    • The control of epidermal stem cells (holoclones) in the treatment of massive full-thickness burns with autologous keratinocytes cultured on fibrin
    • Pellegrini G, Ranno R, Stracuzzi G, Bondanza S, Guerra L, Zambruno G, Micali G, De Luca M (1999) The control of epidermal stem cells (holoclones) in the treatment of massive full-thickness burns with autologous keratinocytes cultured on fibrin. Transplantation 68: 868-879
    • (1999) Transplantation , vol.68 , pp. 868-879
    • Pellegrini, G.1    Ranno, R.2    Stracuzzi, G.3    Bondanza, S.4    Guerra, L.5    Zambruno, G.6    Micali, G.7    De Luca, M.8
  • 51
    • 0345731237 scopus 로고    scopus 로고
    • Cell migration: Rho GTPases lead the way
    • Raftopoulou M, Hall A (2004) Cell migration: Rho GTPases lead the way. Dev Biol 265: 23-32
    • (2004) Dev Biol , vol.265 , pp. 23-32
    • Raftopoulou, M.1    Hall, A.2
  • 52
    • 0016729431 scopus 로고
    • Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells
    • Rheinwald JG, Green H (1975) Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. Cell 6: 331-343
    • (1975) Cell , vol.6 , pp. 331-343
    • Rheinwald, J.G.1    Green, H.2
  • 53
    • 0017349282 scopus 로고
    • Epidermal growth factor and the multiplication of cultured human epidermal keratinocytes
    • Rheinwald JG, Green H (1977) Epidermal growth factor and the multiplication of cultured human epidermal keratinocytes. Nature 265: 421-424
    • (1977) Nature , vol.265 , pp. 421-424
    • Rheinwald, J.G.1    Green, H.2
  • 54
    • 0026654125 scopus 로고
    • The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
    • Ridley AJ, Paterson HF, Johnston CL, Diekmann D, Hall A (1992) The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70: 401-410
    • (1992) Cell , vol.70 , pp. 401-410
    • Ridley, A.J.1    Paterson, H.F.2    Johnston, C.L.3    Diekmann, D.4    Hall, A.5
  • 55
    • 0028267236 scopus 로고
    • Location of stem cells of human hair follicles by clonal analysis
    • Rochat A, Kobayashi K, Barrandon Y (1994) Location of stem cells of human hair follicles by clonal analysis. Cell 76: 1063-1073
    • (1994) Cell , vol.76 , pp. 1063-1073
    • Rochat, A.1    Kobayashi, K.2    Barrandon, Y.3
  • 56
    • 84875786846 scopus 로고    scopus 로고
    • Regeneration of epidermis from adult human keratinocyte stem cells.
    • 2nd edition, Lanza R, Atala A (eds). London, UK: Academic Press
    • Rochat A, Grasset N, Gorostidi F, Lathion S, Barrandon Y (2012) Regeneration of epidermis from adult human keratinocyte stem cells. In Handbook of Stem Cells, 2nd edition, Lanza R, Atala A (eds) pp 767-780. London, UK: Academic Press
    • (2012) Handbook of Stem Cells , pp. 767-780
    • Rochat, A.1    Grasset, N.2    Gorostidi, F.3    Lathion, S.4    Barrandon, Y.5
  • 57
    • 0034671134 scopus 로고    scopus 로고
    • Long-term regeneration of human epidermis on third degree burns transplanted with autologous cultured epithelium grown on a fibrin matrix
    • Ronfard V, Rives JM, Neveux Y, Carsin H, Barrandon Y (2000) Long-term regeneration of human epidermis on third degree burns transplanted with autologous cultured epithelium grown on a fibrin matrix. Transplantation 70: 1588-1598
    • (2000) Transplantation , vol.70 , pp. 1588-1598
    • Ronfard, V.1    Rives, J.M.2    Neveux, Y.3    Carsin, H.4    Barrandon, Y.5
  • 58
    • 0035836715 scopus 로고    scopus 로고
    • Migration of keratinocytes through tunnels of digested fibrin
    • Ronfard V, Barrandon Y (2001) Migration of keratinocytes through tunnels of digested fibrin. Proc Natl Acad Sci USA 98: 4504-4509
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 4504-4509
    • Ronfard, V.1    Barrandon, Y.2
  • 59
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • Sarbassov DD, Guertin DA, Ali SM, Sabatini DM (2005) Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307: 1098-1101
    • (2005) Science , vol.307 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 61
    • 34948891511 scopus 로고    scopus 로고
    • Comparative maps of motion and assembly of filamentous actin and myosin II in migrating cells
    • Schaub S, Bohnet S, Laurent VM, Meister J, Verkhovsky AB (2007) Comparative maps of motion and assembly of filamentous actin and myosin II in migrating cells. Mol Biol Cell 18: 3722-3732
    • (2007) Mol Biol Cell , vol.18 , pp. 3722-3732
    • Schaub, S.1    Bohnet, S.2    Laurent, V.M.3    Meister, J.4    Verkhovsky, A.B.5
  • 62
    • 0029000811 scopus 로고
    • Actin filament organization in the fish keratocyte lamellipodium
    • Small JV, Herzog M, Anderson K (1995) Actin filament organization in the fish keratocyte lamellipodium. J Cell Biol 129: 1275-1286
    • (1995) J Cell Biol , vol.129 , pp. 1275-1286
    • Small, J.V.1    Herzog, M.2    Anderson, K.3
  • 65
    • 77950818679 scopus 로고    scopus 로고
    • Efficient procurement of epithelial stem cells from human tissue specimens using a Rho-associated protein kinase inhibitor Y-27632
    • Terunuma A, Limgala RP, Park CJ, Choudhary I, Vogel JC (2010) Efficient procurement of epithelial stem cells from human tissue specimens using a Rho-associated protein kinase inhibitor Y-27632. Tissue Eng Part A 16: 1363-1368
    • (2010) Tissue Eng Part A , vol.16 , pp. 1363-1368
    • Terunuma, A.1    Limgala, R.P.2    Park, C.J.3    Choudhary, I.4    Vogel, J.C.5
  • 66
    • 33744948789 scopus 로고    scopus 로고
    • AKT1 provides an essential survival signal required for differentiation and stratification of primary human keratinocytes
    • Thrash B, Menges CW, Pierce RH, McCance DJ (2006) AKT1 provides an essential survival signal required for differentiation and stratification of primary human keratinocytes. J Biol Chem 281: 12155-12162
    • (2006) J Biol Chem , vol.281 , pp. 12155-12162
    • Thrash, B.1    Menges, C.W.2    Pierce, R.H.3    McCance, D.J.4
  • 67
    • 0842288222 scopus 로고    scopus 로고
    • Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts
    • Totsukawa G, Wu Y, Sasaki Y, Hartshorne DJ, Yamakita Y, Yamashiro S, Matsumura F (2004) Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts. J Cell Biol 164: 427-439
    • (2004) J Cell Biol , vol.164 , pp. 427-439
    • Totsukawa, G.1    Wu, Y.2    Sasaki, Y.3    Hartshorne, D.J.4    Yamakita, Y.5    Yamashiro, S.6    Matsumura, F.7
  • 68
    • 0036746704 scopus 로고    scopus 로고
    • Actin cable dynamics and Rho/Rock orchestrate a polarized cytoskeletal architecture in the early steps of assembling a stratified epithelium
    • Vaezi A, Bauer C, Vasioukhin V, Fuchs E (2002) Actin cable dynamics and Rho/Rock orchestrate a polarized cytoskeletal architecture in the early steps of assembling a stratified epithelium. Dev Cell 3: 367-381
    • (2002) Dev Cell , vol.3 , pp. 367-381
    • Vaezi, A.1    Bauer, C.2    Vasioukhin, V.3    Fuchs, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.