Prebiotic fiber increases hepatic acetyl CoA carboxylase phosphorylation and suppresses glucose-dependent insulinotropic polypeptide secretion more effectively when used with metformin in obese rats

Journal of Nutrition

Volumn 142, Issue 2, 2012, Pages 213-220

  Pyra, Kim A ^a   Saha, Dolan C ^a   Reimer, Raylene A ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; AMYLIN; DIPEPTIDYL PEPTIDASE IV; FRUCTOSE OLIGOSACCHARIDE; GASTRIC INHIBITORY POLYPEPTIDE; GHRELIN; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; LEPTIN; MESSENGER RNA; METFORMIN; RAFTILOSE P95; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTEROIDES; BIFIDOBACTERIUM; BODY COMPOSITION; BODY FAT; BODY WEIGHT; BONE MINERAL; CECUM; CLOSTRIDIUM; CLOSTRIDIUM COCCOIDES; CONTROLLED STUDY; DRUG EFFECT; ENTEROBACTERIACEAE; ENTEROENDOCRINE CELL; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME PHOSPHORYLATION; FATTY ACID SYNTHESIS; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HORMONE BLOOD LEVEL; INSULIN BLOOD LEVEL; INTESTINE FLORA; LACTOBACILLUS; LIPID DIET; LIPID LIVER LEVEL; MALE; NONHUMAN; OBESITY; PREVOTELLA; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; SATIETY; SUGAR INTAKE; WEIGHT GAIN; WESTERN BLOTTING;

ACETYL-COA CARBOXYLASE; ADENYLATE KINASE; ANIMALS; BLOOD GLUCOSE; BODY COMPOSITION; DIETARY FIBER; DIPEPTIDYL PEPTIDASE 4; EATING; GASTRIC INHIBITORY POLYPEPTIDE; GASTROINTESTINAL TRACT; GLUCAGON-LIKE PEPTIDE 1; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; LIVER; MALE; METFORMIN; OBESITY; OLIGOSACCHARIDES; PHOSPHORYLATION; PREBIOTICS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 84858251477     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.111.147132     Document Type: Article

References (42)

1. Walsh SJ, Dauser-Forrest D. Correlates of weight loss in persons with metabolic syndrome. Prev Med. 2009;49:396-401.
2. Ranganath LR, Beety JM, Morgan LM, Wright JW, Howland R, Marks V. Attenuated GLP-1 secretion in obesity: cause or consequence. Gut. 1996;38:916-9.
3. Verdich C, Toubro S, Buemann B, Madsen JL, Holst JJ, Astrup A. The role of postprandial releases of insulin and incretin hormones in mealinduced satiety: effect of obesity and weight reduction. Int J Obes Relat Metab Disord. 2001;25:1206-14.
4. Vilsbøll T, Krarup T, Deacon CF, Madsbad S, Holst JJ. Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients. Diabetes. 2001;50:609-13.
5. Blundell JE, Levin F, King NA, Barkeling B, Gustafsson T, Hellstrom PM, Holst JJ, Naslund E. Overconsumption and obesity: peptides and susceptibility to weight gain. Regul Pept. 2008;149:32-8.
6. Delzenne NM. Oligosaccharides: state of the art. Proc Nutr Soc. 2003;62:177-82.
7. Cani PD, Knauf C, Iglesias MA, Drucker DJ, Delzenne NM, Burcelin R. Improvement of glucose tolerance and hepatic insulin sensitivity by oligofructose requires a functional glucagon-like peptide-1 receptor. Diabetes. 2006;55:1484-90.
8. Parnell JA, Reimer RA. Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults. Am J Clin Nutr. 2009;89:1751-9.
9. Delzenne NM, Cani PD, Neyrinck AM. Modulation of glucagon-like peptide 1 and energy metabolism by inulin and oligofructose: experimental data. J Nutr. 2007;137:S2547-51.
10. Cani PD, Neyrinck AM, Maton N, Delzenne NM. Oligofructose promotes satiety in rats fed a high-fat diet: involvement of glucagon-like peptide-1. Obes Res. 2005;13:1000-7.
11. Zhou J, Martin RJ, Tulley RT, Raggio AM, McCutcheon KL, Shen L, Danna SC, Tripathy D, Hegsted M, Keenan MJ. et al. Dietary resistant starch upregulates total GLP-1 and PYY in a sustained day-long manner through fermentation in rodents. Am J Physiol Endocrinol Metab. 2008;295:E1160-6.
12. Cani PD, Possemiers S, Van de Wiele T, Guiot Y, Everard A, Rottier O, Geurts L, Naslain D, Neyrinck A, Lambert DM, et al. Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement in gut permeability. Gut. 2009;58:1091-103.
13. Papanas N, Maltezos E, Mikhailidis D. Metformin: diamonds are forever. Expert Opin Pharmacother. 2009;10:2395-7.
14. Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, Wu M, Ventre J, Doebber T, Fujii N, et al. Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest. 2001;108:1167-74.
15. Viollet B, Guigas B, Leclerc J, Hebrard S, Lantier L, Mounier R, Andreelli F, Foretz M. AMP-activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives. Acta Physiol (Oxf). 2009;196:81-98.
16. Mannucci E, Ognibene A, Cremasco F, Bardini G, Mencucci A, Pierazzuoli E, Ciani S, Messeri G, Rotella CM. Effect of metformin on glucagon-like peptide 1 (GLP-1) and leptin levels in obese nondiabetic subjects. Diabetes Care. 2001;24:489-94.
17. Yasuda N, Inoue T, Nagakura T, Yamazaki K, Kira K, Saeki T, Tanaka H. Enhanced secretion of glucagon-like peptide 1 by biguanide compounds. Biochem Biophys Res Commun. 2002;298:779-84.
18. Kim Y-W, Kim J-Y, Park Y-H, Park S-Y, Won K-C, Choi K-H, Huh J-Y, Moon K-H. Metformin restores leptin sensitivity in high fat-fed obese rats with leptin resistance. Diabetes. 2006;55:716-24.
19. Eller LK, Reimer RA. A high calcium, skim milk powder diet results in a lower fat mass in male, energy-restricted, obese rats more than a low calcium, casein or soy protein diet. J Nutr. 2010;140:1234-41.
20. Parnell JA, Reimer RA. Effect of prebiotic fiber supplementation on hepatic gene expression and serum lipids: a dose-response study in JCR: LA-cp rats. Br J Nutr. 2010;103:1577-84.
21. Maurer AD, Chen Q, McPherson C, Reimer RA. Changes in satiety hormones and expression of genes involved in glucose and lipid metabolism in rats weaned onto diets high in fiber or protein reflect susceptibility to increased fat mass in adulthood. J Physiol. 2009; 587:679-91.
22. Kirino Y, Kamimoto T, Sata Y, Kawazoe K, Minakuchi K, Nakahori Y. Increased plasma dipeptidyl peptidase IV (DPP IV) activity and decreased DPP IV activity of visceral but not subcutaneous adipose tissue in impaired glucose tolerance rats induced by high-fat or highsucrose diet. Biol Pharm Bull. 2009;32:463-7.
23. Reimer RA. Meat hydrolysate and essential amino acid-induced glucagon like peptide-1 secretion in the human enteroendocrine NCI-H716 cell line is regulated by extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinases. J Endocrinol. 2006;191:159-70.
24. Parnell JA, Reimer RA. Prebiotic fibres dose-dependently increase satiety hormones and alter Bacteroidetes and Firmicutes in lean and obese JCR:LA cp rats. Br J Nutr. Epub 2011 Jul 18.
25. Reimer RA, Darimont C, Nicolas-Metral V, Gremlich S, Rüegg UT, Macé K. A human cellular model for studying the regulation of glucagon-like peptide 1 secretion. Endocrinology. 2001;142:4522-8.
26. Mentlein R. Mechanisms underlying the rapid degradation and elimination of the incretin hormones GLP-1 and GIP. Best Pract Res Clin Endocrinol Metab. 2009;23:443-52.
27. He L, Sabet A, Djedjos S, Miller R, Sun X, Hussain MA, Radovick S, Wondisford FE. Meformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein. Cell. 2009;137: 635-46.
28. Delmée E, Cani PD, Gual G, Knauf C, Burcelin R, Maton N, Delzenne NM. Relation between colonic proglucagon expression and metabolic response to oligofructose in high fat diet-fed mice. Life Sci. 2006;79:1007-13.
29. Roden M, Petersen KF, Schulman G. Nuclear magnetic resonance studies of hepatic glucose metabolism in humans. Recent Prog Horm Res. 2001;56:219-37.
30. Rector RS, Thyfault JP, Morris RT, Laye MJ, Borengasser SJ, Booth FW, Ibdah JA. Daily exercise increases hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima fatty rats. Am J Physiol Gastrointest Liver Physiol. 2008;294:G619-26.
31. Andreelli F, Foretz M, Knauf C, Cani PD, Perrin C, Iglesias MA, Pillot B, Bado A, Tronche F, Mithieux G, et al. Liver adenosine monophosphate-activated kinase a2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but no insulin. Endocrinology. 2006;147:2432-41.
32. Gniuli D, Calcagno A, Dalla Libera L, Calvani R, Leccesi L, Caristo ME, Vettor R, Castagneto M, Ghirlanda G, Mingrone G. et al. High-fat feeding stimulates endocrine, glucose-dependent insulinotropic polypeptide (GIP)-expressing cell hyperplasia in the duodenum of Wistar rats. Diabetologia. 2010;53:2233-40.
33. Mazzaferri EL, Starich GH, Lardinois CK, Bowen GD. Gastric inhibitory polypeptide responses to nutrients in Caucasians and American Indians with obesity and noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab. 1985;61:313-21.
34. Miyawaki K, Yamada Y, Ban N, Ihara T, Tsukiyama K, Zhou H, Fujimoto S, Oku A, Tsuda K, Toyokuni S, et al. Inhibition of gastric inhibitory polypeptide signaling prevents obesity. Nat Med. 2002;8: 738-42.
35. Kim SJ, Nian C, McIntosh CH. Resistin is a key mediator of glucosedependent insulinotropic polypeptide (GIP) stimulation of lipoprotein lipase (LPL) activity in adipocytes. J Biol Chem. 2007;282:34139-47.
36. Musso G, Gambino R, Pacini G, De Michieli F, Cassader M. Prolonged saturated fat-induced, glucose-dependent insulinotropic polypeptide elevation is associated with adipokine imbalance and liver injury in nonalcoholic steatohepatitis: dysregulated enteroadipocyte axis as a novel feature of fatty liver. Am J Clin Nutr. 2009;89:558-67.
37. Ley RE, Turnbaugh PJ, Klein S, Gordon JI. Human gut microbes associated with obesity. Nature. 2006;444:1022-3.
38. Turnbaugh PJ, Ley RE, Mahowald MA, Magrini V, Mardis ER, Gordon JI. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature. 2006;444:1027-31.
39. Bäckhed F, Manchester JK, Semenkovich CF, Gordon JI. Mechanisms underlying the resistance to diet-induced obesity in germ-free mice. Proc Natl Acad Sci USA. 2007;104:979-84.
40. Santacruz A, Collado MC, Garcia-Valdes L, Segura MT, Martin-Lagos JA, Marti-Romero M, Lopez RM, Florido J, Campoy C, Sanz Y. et al. Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women. Br J Nutr. 2010; 104:83-92.
41. Alam ML, Van der Schueren BJ, Ahren B, Wang GC, Swerdlow NJ, Arias S, Bose M, Gorroochurn P, Teixeira J, McGinty J, et al. Gastric bypass surgery, but not caloric restriction, decreases dipeptidyl peptidase-4 activity in obese patients with type 2 diabetes. Diabetes Obes Metab. 2011;13:378-81.
42. Zardooz H, Rostamkhani F, Zaringhalam J, Faraji Shahrivar F. Plasma corticosterone, insulin and glucose changes induced by brief exposure to isoflurane, diethyl ether and CO2 in male rats. Physiol Res. 2010;59: 973-8.