-
2
-
-
0003635217
-
-
World Health Organization [Accessed 13 August 2012.] Available from URL
-
World Health Organization. Global tuberculosis control 2011. 2011: 1-258. [Accessed 13 August 2012.] Available from URL: http://www.who.int/tb/ publications/global-report/2011/gtbr11-full.pdf
-
(2011)
Global Tuberculosis Control 2011
, pp. 1-258
-
-
-
3
-
-
69549083228
-
Epidemiological benefits of more-effective tuberculosis vaccines, drugs, and diagnostics
-
Abu-Raddad LJ, Sabatelli L, Achterberg JT, et al. Epidemiological benefits of more-effective tuberculosis vaccines, drugs, and diagnostics. Proc. Natl Acad. Sci. U.S.A. 2009; 106: 13980-13985.
-
(2009)
Proc. Natl Acad. Sci. U.S.A.
, vol.106
, pp. 13980-13985
-
-
Abu-Raddad, L.J.1
Sabatelli, L.2
Achterberg, J.T.3
-
4
-
-
77958481160
-
Future vaccination strategies against tuberculosis: Thinking outside the box
-
Kaufmann SHE,. Future vaccination strategies against tuberculosis: thinking outside the box. Immunity 2010; 33: 567-577.
-
(2010)
Immunity
, vol.33
, pp. 567-577
-
-
Kaufmann, S.H.E.1
-
5
-
-
84958048417
-
Protective vaccination against tuberculosis with special reference to BCG vaccine
-
Aronson J,. Protective vaccination against tuberculosis with special reference to BCG vaccine. Am. Rev. Tuberc. 1948; 58: 55-81.
-
(1948)
Am. Rev. Tuberc.
, vol.58
, pp. 55-81
-
-
Aronson, J.1
-
6
-
-
0016042532
-
Evaluation of BCG vaccination among Puerto Rican children
-
Comstock G, Livesay V, Woolpert S,. Evaluation of BCG vaccination among Puerto Rican children. Am. J. Public Health 1974; 64: 284-291.
-
(1974)
Am. J. Public Health
, vol.64
, pp. 284-291
-
-
Comstock, G.1
Livesay, V.2
Woolpert, S.3
-
7
-
-
47549116006
-
Vaccines: Correlates of vaccine-induced immunity
-
Plotkin SA,. Vaccines: correlates of vaccine-induced immunity. Clin. Infect. Dis. 2008; 47: 401-409.
-
(2008)
Clin. Infect. Dis.
, vol.47
, pp. 401-409
-
-
Plotkin, S.A.1
-
8
-
-
49749093396
-
Immunopathogenesis of tuberculosis: Implications for vaccine development
-
Zhang Y,. Immunopathogenesis of tuberculosis: implications for vaccine development. Respirology 2008; 13: S81-S87.
-
(2008)
Respirology
, vol.13
-
-
Zhang, Y.1
-
9
-
-
78649629273
-
BCG vaccination: 90 years on and still so much to learn
-
Lalvani A, Sridhar S,. BCG vaccination: 90 years on and still so much to learn. Thorax 2010; 65: 1036-1038.
-
(2010)
Thorax
, vol.65
, pp. 1036-1038
-
-
Lalvani, A.1
Sridhar, S.2
-
10
-
-
77958475885
-
Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after Bacillus Calmette-Guerin vaccination of newborns
-
Kagina BMN, Abel B, Scriba TJ, et al. Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after Bacillus Calmette-Guerin vaccination of newborns. Am. J. Respir. Crit. Care Med. 2010; 182: 1073-1079.
-
(2010)
Am. J. Respir. Crit. Care Med.
, vol.182
, pp. 1073-1079
-
-
Kagina, B.M.N.1
Abel, B.2
Scriba, T.J.3
-
11
-
-
0035100888
-
Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
-
Biomarkers Definitions Working Group.
-
Biomarkers Definitions Working Group. Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin. Pharmacol. Ther. 2001; 69: 89-95.
-
(2001)
Clin. Pharmacol. Ther.
, vol.69
, pp. 89-95
-
-
-
12
-
-
0347269081
-
Immunology of tuberculosis and implications in vaccine development
-
Flynn JL,. Immunology of tuberculosis and implications in vaccine development. Tuberculosis 2004; 84: 93-101.
-
(2004)
Tuberculosis
, vol.84
, pp. 93-101
-
-
Flynn, J.L.1
-
13
-
-
77950262301
-
The immunology of tuberculosis: From bench to bedside
-
Dheda K, Schwander S, Zhu B, et al. The immunology of tuberculosis: from bench to bedside. Respirology 2010; 15: 433-450.
-
(2010)
Respirology
, vol.15
, pp. 433-450
-
-
Dheda, K.1
Schwander, S.2
Zhu, B.3
-
14
-
-
15844380037
-
Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis
-
Nicholson S, Bonecini-Almeida MDG, Lapa e Silva JR, et al. Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis. J. Exp. Med. 1996; 183: 2293-2302.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2293-2302
-
-
Nicholson, S.1
Bonecini-Almeida, M.D.G.2
Lapa Silva E, J.R.3
-
15
-
-
0001211310
-
Response of cultured macrophages to Mycobacterium tuberculosis, with observations on fusion of lysosomes with phagosomes
-
Armstrong J, D'Arcy Hart P,. Response of cultured macrophages to Mycobacterium tuberculosis, with observations on fusion of lysosomes with phagosomes. J. Exp. Med. 1971; 134: 713-740.
-
(1971)
J. Exp. Med.
, vol.134
, pp. 713-740
-
-
Armstrong, J.1
D'Arcy Hart, P.2
-
16
-
-
38749138163
-
Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs
-
Wolf AJ, Desvignes L, Linas B, et al. Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs. J. Exp. Med. 2008; 205: 105-115.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 105-115
-
-
Wolf, A.J.1
Desvignes, L.2
Linas, B.3
-
17
-
-
77953316728
-
Secondary lymphoid organs are dispensable for the development of T-cell-mediated immunity during tuberculosis
-
Day TA, Koch M, Nouailles G, et al. Secondary lymphoid organs are dispensable for the development of T-cell-mediated immunity during tuberculosis. Eur. J. Immunol. 2010; 40: 1663-1673.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 1663-1673
-
-
Day, T.A.1
Koch, M.2
Nouailles, G.3
-
18
-
-
84856083753
-
Floating between the poles of pathology and protection: Can we pin down the granuloma in tuberculosis?
-
Reece ST, Kaufmann S,. Floating between the poles of pathology and protection: can we pin down the granuloma in tuberculosis? Curr. Opin. Microbiol. 2011; 15: 63-70.
-
(2011)
Curr. Opin. Microbiol.
, vol.15
, pp. 63-70
-
-
Reece, S.T.1
Kaufmann, S.2
-
19
-
-
84863690353
-
Vaccines against tuberculosis: Where are we and where do we need to go?
-
Chitnis C.E. ed.
-
Ottenhoff THM, Kaufmann SHE,. Vaccines against tuberculosis: where are we and where do we need to go?, Chitnis CE, ed. PLoS Pathog. 2012; 8: e1002607.
-
(2012)
PLoS Pathog.
, vol.8
-
-
Ottenhoff, T.H.M.1
Kaufmann, S.H.E.2
-
20
-
-
84858419788
-
Beyond empiricism: Informing vaccine development through innate immunity research
-
Levitz SM, Golenbock DT,. Beyond empiricism: informing vaccine development through innate immunity research. Cell 2012; 148: 1284-1292.
-
(2012)
Cell
, vol.148
, pp. 1284-1292
-
-
Levitz, S.M.1
Golenbock, D.T.2
-
21
-
-
84856693171
-
Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections
-
Tobin DM, Roca FJ, Oh SF, et al. Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Cell 2012; 148: 434-446.
-
(2012)
Cell
, vol.148
, pp. 434-446
-
-
Tobin, D.M.1
Roca, F.J.2
Oh, S.F.3
-
22
-
-
79956302280
-
Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas
-
Egen JG, Rothfuchs AG, Feng CG, et al. Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas. Immunity 2011; 34: 807-819.
-
(2011)
Immunity
, vol.34
, pp. 807-819
-
-
Egen, J.G.1
Rothfuchs, A.G.2
Feng, C.G.3
-
23
-
-
67650932256
-
Cell-mediated immune responses in tuberculosis
-
Cooper AM,. Cell-mediated immune responses in tuberculosis. Annu. Rev. Immunol. 2009; 27: 393-422.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 393-422
-
-
Cooper, A.M.1
-
24
-
-
77955390095
-
Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis
-
Cruz A, Fraga AG, Fountain JJ, et al. Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis. J. Exp. Med. 2010; 207: 1609-1616.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1609-1616
-
-
Cruz, A.1
Fraga, A.G.2
Fountain, J.J.3
-
25
-
-
77649260171
-
Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8+ T-cells with cytotoxic as well as regulatory activity
-
Joosten SA, van Meijgaarden KE, van Weeren PC, et al. Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8+ T-cells with cytotoxic as well as regulatory activity. PLoS Pathog. 2010; 6: e1000782.
-
(2010)
PLoS Pathog.
, vol.6
-
-
Joosten, S.A.1
Van Meijgaarden, K.E.2
Van Weeren, P.C.3
-
26
-
-
57649090701
-
Human CD4 and CD8 regulatory T cells in infectious diseases and vaccination
-
Joosten SA, Ottenhoff THM,. Human CD4 and CD8 regulatory T cells in infectious diseases and vaccination. Hum. Immunol. 2008; 69: 760-770.
-
(2008)
Hum. Immunol.
, vol.69
, pp. 760-770
-
-
Joosten, S.A.1
Ottenhoff, T.H.M.2
-
27
-
-
34447126847
-
Neutrophil-mediated innate immune resistance to mycobacteria
-
Martineau AR, Newton SM, Wilkinson KA, et al. Neutrophil-mediated innate immune resistance to mycobacteria. J. Clin. Invest. 2007; 117: 1988-1994.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1988-1994
-
-
Martineau, A.R.1
Newton, S.M.2
Wilkinson, K.A.3
-
29
-
-
84859429244
-
Mycobacterium tuberculosis: Success through dormancy
-
Gengenbacher M, Kaufmann SHE,. Mycobacterium tuberculosis: success through dormancy. FEMS Microbiol. Rev. 2012; 36: 514-532.
-
(2012)
FEMS Microbiol. Rev.
, vol.36
, pp. 514-532
-
-
Gengenbacher, M.1
Kaufmann, S.H.E.2
-
30
-
-
84855195248
-
Characterization and transcriptome analysis of Mycobacterium tuberculosis persisters
-
Keren I, Minami S, Rubin E, et al. Characterization and transcriptome analysis of Mycobacterium tuberculosis persisters. MBio. 2011; 2: e00100-00111.
-
(2011)
MBio.
, vol.2
-
-
Keren, I.1
Minami, S.2
Rubin, E.3
-
33
-
-
79751497607
-
A multistage tuberculosis vaccine that confers efficient protection before and after exposure
-
Aagaard C, Hoang T, Dietrich J, et al. A multistage tuberculosis vaccine that confers efficient protection before and after exposure. Nat. Med. 2011; 17: 189-194.
-
(2011)
Nat. Med.
, vol.17
, pp. 189-194
-
-
Aagaard, C.1
Hoang, T.2
Dietrich, J.3
-
34
-
-
78650240549
-
Prospects for a new, safer and more effective TB vaccine
-
Hawkridge T, Mahomed H,. Prospects for a new, safer and more effective TB vaccine. Paediatr. Respir. Rev. 2011; 12: 46-51.
-
(2011)
Paediatr. Respir. Rev.
, vol.12
, pp. 46-51
-
-
Hawkridge, T.1
Mahomed, H.2
-
35
-
-
77953534743
-
Novel tuberculosis vaccines on the horizon
-
Parida SK, Kaufmann SH,. Novel tuberculosis vaccines on the horizon. Curr. Opin. Immunol. 2010; 22: 374-384.
-
(2010)
Curr. Opin. Immunol.
, vol.22
, pp. 374-384
-
-
Parida, S.K.1
Kaufmann, S.H.2
-
37
-
-
84861038873
-
Immunogenicity and protective efficacy of a novel recombinant BCG strain overexpressing antigens Ag85A and Ag85B
-
Wang C, Fu R, Chen Z, et al. Immunogenicity and protective efficacy of a novel recombinant BCG strain overexpressing antigens Ag85A and Ag85B. Clin. Dev. Immunol. 2012; 2012: 563838.
-
(2012)
Clin. Dev. Immunol.
, vol.2012
, pp. 563838
-
-
Wang, C.1
Fu, R.2
Chen, Z.3
-
38
-
-
80053963965
-
A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis
-
Sweeney KA, Dao DN, Goldberg MF, et al. A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis. Nat. Med. 2011; 17: 1261-1268.
-
(2011)
Nat. Med.
, vol.17
, pp. 1261-1268
-
-
Sweeney, K.A.1
Dao, D.N.2
Goldberg, M.F.3
-
39
-
-
84862640434
-
Tuberculosis vaccine development: Strength lies in tenacity
-
Kaufmann SHE,. Tuberculosis vaccine development: strength lies in tenacity. Trends Immunol. 2012; 33: 373-379.
-
(2012)
Trends Immunol.
, vol.33
, pp. 373-379
-
-
Kaufmann, S.H.E.1
-
40
-
-
84855467363
-
The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection
-
Lin PL, Dietrich J, Tan E, et al. The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection. J. Clin. Invest. 2012; 122: 303-314.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 303-314
-
-
Lin, P.L.1
Dietrich, J.2
Tan, E.3
-
41
-
-
84862776959
-
Immunogenicity and protective efficacy of a tuberculosis DNA vaccine expressing a fusion protein of Ag85B-Esat6-HspX in mice
-
Yuan W, Dong N, Zhang L, et al. Immunogenicity and protective efficacy of a tuberculosis DNA vaccine expressing a fusion protein of Ag85B-Esat6-HspX in mice. Vaccine 2012; 30: 2490-2497.
-
(2012)
Vaccine
, vol.30
, pp. 2490-2497
-
-
Yuan, W.1
Dong, N.2
Zhang, L.3
-
42
-
-
81955164734
-
Construction and evaluation of a multistage Mycobacterium tuberculosis subunit vaccine candidate Mtb10.4-HspX
-
Niu H, Hu L, Li Q, et al. Construction and evaluation of a multistage Mycobacterium tuberculosis subunit vaccine candidate Mtb10.4-HspX. Vaccine 2011; 29: 9451-9458.
-
(2011)
Vaccine
, vol.29
, pp. 9451-9458
-
-
Niu, H.1
Hu, L.2
Li, Q.3
-
43
-
-
77954956888
-
Enhanced protection against tuberculosis by vaccination with recombinant BCG over-expressing HspX protein
-
Shi C, Chen L, Chen Z, et al. Enhanced protection against tuberculosis by vaccination with recombinant BCG over-expressing HspX protein. Vaccine 2010; 28: 5237-5244.
-
(2010)
Vaccine
, vol.28
, pp. 5237-5244
-
-
Shi, C.1
Chen, L.2
Chen, Z.3
-
44
-
-
80051716214
-
A booster vaccine expressing a latency-Associated antigen augments BCG induced immunity and confers enhanced protection against tuberculosis
-
Dey B, Jain R, Gupta UD, et al. A booster vaccine expressing a latency-Associated antigen augments BCG induced immunity and confers enhanced protection against tuberculosis. PLoS ONE 2011; 6: e23360.
-
(2011)
PLoS ONE
, vol.6
-
-
Dey, B.1
Jain, R.2
Gupta, U.D.3
-
45
-
-
84870497861
-
HspX-mediated protection against tuberculosis depends on its chaperoning of a mycobacterial molecule
-
Taylor JL, Wieczorek A, Keyser AR, et al. HspX-mediated protection against tuberculosis depends on its chaperoning of a mycobacterial molecule. Immunol. Cell Biol. 2012; 00: 1-10.
-
(2012)
Immunol. Cell Biol.
, vol.0
, pp. 1-10
-
-
Taylor, J.L.1
Wieczorek, A.2
Keyser, A.R.3
-
46
-
-
79955400032
-
Immunogenicity and protective efficacy of a fusion protein vaccine consisting of antigen Ag85B and HspX against Mycobacterium tuberculosis infection in mice
-
Li Q, Yu H, Zhang Y, et al. Immunogenicity and protective efficacy of a fusion protein vaccine consisting of antigen Ag85B and HspX against Mycobacterium tuberculosis infection in mice. Scand. J. Immunol. 2011; 73: 568-576.
-
(2011)
Scand. J. Immunol.
, vol.73
, pp. 568-576
-
-
Li, Q.1
Yu, H.2
Zhang, Y.3
-
47
-
-
84858997919
-
Preclinical evidence for implementing a prime-boost vaccine strategy for tuberculosis
-
Brennan MJ, Clagett B, Fitzgerald H, et al. Preclinical evidence for implementing a prime-boost vaccine strategy for tuberculosis. Vaccine 2012; 30: 2811-2823.
-
(2012)
Vaccine
, vol.30
, pp. 2811-2823
-
-
Brennan, M.J.1
Clagett, B.2
Fitzgerald, H.3
-
48
-
-
4644324023
-
Methylation-dependent T cell immunity to Mycobacterium tuberculosis heparin-binding hemagglutinin
-
Temmerman S, Pethe K, Parra M, et al. Methylation-dependent T cell immunity to Mycobacterium tuberculosis heparin-binding hemagglutinin. Nat. Med. 2004; 10: 935-941.
-
(2004)
Nat. Med.
, vol.10
, pp. 935-941
-
-
Temmerman, S.1
Pethe, K.2
Parra, M.3
-
49
-
-
77952744996
-
Boosting with mycobacterial heparin-binding haemagglutinin enhances protection of Mycobacterium bovis BCG-vaccinated newborn mice against M. tuberculosis
-
Guerrero GG, Debrie A-S, Locht C,. Boosting with mycobacterial heparin-binding haemagglutinin enhances protection of Mycobacterium bovis BCG-vaccinated newborn mice against M. tuberculosis. Vaccine 2010; 28: 4340-4347.
-
(2010)
Vaccine
, vol.28
, pp. 4340-4347
-
-
Guerrero, G.G.1
Debrie, A.-S.2
Locht, C.3
-
50
-
-
7044270950
-
Application of mycobacterial proteomics to vaccine design: Improved protection by Mycobacterium bovis BCG prime-Rv3407 DNA boost vaccination against tuberculosis
-
Mollenkopf H-J, Grode L, Mattow J, et al. Application of mycobacterial proteomics to vaccine design: improved protection by Mycobacterium bovis BCG prime-Rv3407 DNA boost vaccination against tuberculosis. Infect. Immun. 2004; 72: 6471-6479.
-
(2004)
Infect. Immun.
, vol.72
, pp. 6471-6479
-
-
Mollenkopf, H.-J.1
Grode, L.2
Mattow, J.3
-
51
-
-
79955084247
-
Immunogenicity and protective efficacy against murine tuberculosis of a prime-boost regimen with BCG and a DNA vaccine expressing ESAT-6 and Ag85A fusion protein
-
Lu J, Wang C, Zhou Z, et al. Immunogenicity and protective efficacy against murine tuberculosis of a prime-boost regimen with BCG and a DNA vaccine expressing ESAT-6 and Ag85A fusion protein. Clin. Dev. Immunol. 2011; 2011: 617892.
-
(2011)
Clin. Dev. Immunol.
, vol.2011
, pp. 617892
-
-
Lu, J.1
Wang, C.2
Zhou, Z.3
-
52
-
-
79961208433
-
A DNA vaccine expressing CFP21 and MPT64 fusion protein enhances BCG-induced protective immunity against Mycobacterium tuberculosis infection in mice
-
Wang C, Chen Z, Fu R, et al. A DNA vaccine expressing CFP21 and MPT64 fusion protein enhances BCG-induced protective immunity against Mycobacterium tuberculosis infection in mice. Med. Microbiol. Immunol. 2011; 200: 165-175.
-
(2011)
Med. Microbiol. Immunol.
, vol.200
, pp. 165-175
-
-
Wang, C.1
Chen, Z.2
Fu, R.3
-
53
-
-
64049113596
-
How B cells shape the immune response against Mycobacterium tuberculosis
-
Maglione PJ, Chan J,. How B cells shape the immune response against Mycobacterium tuberculosis. Eur. J. Immunol. 2009; 39: 676-686.
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 676-686
-
-
Maglione, P.J.1
Chan, J.2
-
54
-
-
78751648792
-
Human gene expression profiles of susceptibility and resistance in tuberculosis
-
Maertzdorf J, Repsilber D, Parida SK, et al. Human gene expression profiles of susceptibility and resistance in tuberculosis. Genes Immun. 2011; 12: 15-22.
-
(2011)
Genes Immun.
, vol.12
, pp. 15-22
-
-
Maertzdorf, J.1
Repsilber, D.2
Parida, S.K.3
-
55
-
-
77952841173
-
Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved
-
Comas I, Chakravartti J, Small PM, et al. Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved. Nat. Genet. 2010; 42: 498-503.
-
(2010)
Nat. Genet.
, vol.42
, pp. 498-503
-
-
Comas, I.1
Chakravartti, J.2
Small, P.M.3
-
56
-
-
84856387609
-
Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection
-
Barreiro L, Tailleux L, Pai A, et al. Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection. Proc. Natl Acad. Sci. U.S.A. 2012; 109: 1-6.
-
(2012)
Proc. Natl Acad. Sci. U.S.A.
, vol.109
, pp. 1-6
-
-
Barreiro, L.1
Tailleux, L.2
Pai, A.3
-
57
-
-
77954623962
-
Airway luminal T cells: A newcomer on the stage of TB vaccination strategies
-
Jeyanathan M, Heriazon A, Xing Z,. Airway luminal T cells: a newcomer on the stage of TB vaccination strategies. Trends Immunol. 2010; 31: 247-252.
-
(2010)
Trends Immunol.
, vol.31
, pp. 247-252
-
-
Jeyanathan, M.1
Heriazon, A.2
Xing, Z.3
-
59
-
-
45449110225
-
Systems biology of persistent infection: Tuberculosis as a case study
-
Young D, Stark J, Kirschner D,. Systems biology of persistent infection: tuberculosis as a case study. Nat. Rev. Microbiol. 2008; 6: 520-528.
-
(2008)
Nat. Rev. Microbiol.
, vol.6
, pp. 520-528
-
-
Young, D.1
Stark, J.2
Kirschner, D.3
-
60
-
-
33748605597
-
Kinetic modeling of tricarboxylic acid cycle and glyoxylate bypass in Mycobacterium tuberculosis, and its application to assessment of drug targets
-
Singh VK, Ghosh I,. Kinetic modeling of tricarboxylic acid cycle and glyoxylate bypass in Mycobacterium tuberculosis, and its application to assessment of drug targets. Theor. Biol. Med. Model. 2006; 3: 27-38.
-
(2006)
Theor. Biol. Med. Model.
, vol.3
, pp. 27-38
-
-
Singh, V.K.1
Ghosh, I.2
-
61
-
-
78049306942
-
Systems biology approaches to understanding mycobacterial survival mechanisms
-
Boshoff HIM, Lun DS,. Systems biology approaches to understanding mycobacterial survival mechanisms. Drug Discov. Today Dis. Mech. 2010; 7: e75-e82.
-
(2010)
Drug Discov. Today Dis. Mech.
, vol.7
-
-
Boshoff, H.I.M.1
Lun, D.S.2
-
62
-
-
77249117661
-
A systems perspective of host-pathogen interactions: Predicting disease outcome in tuberculosis
-
Raman K, Bhat AG, Chandra N,. A systems perspective of host-pathogen interactions: predicting disease outcome in tuberculosis. Mol. BioSyst. 2010; 6: 516-530.
-
(2010)
Mol. BioSyst.
, vol.6
, pp. 516-530
-
-
Raman, K.1
Bhat, A.G.2
Chandra, N.3
-
63
-
-
34548861262
-
GSMN-TB: A web-based genome-scale network model of Mycobacterium tuberculosis metabolism
-
Beste DJV, Hooper T, Stewart G, et al. GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolism. Genome Biol. 2007; 8: R89.
-
(2007)
Genome Biol.
, vol.8
-
-
Beste, D.J.V.1
Hooper, T.2
Stewart, G.3
-
64
-
-
34447317247
-
Investigating the metabolic capabilities of Mycobacterium tuberculosis H37Rv using the in silico strain iNJ661 and proposing alternative drug targets
-
Jamshidi N, Palsson BØ,. Investigating the metabolic capabilities of Mycobacterium tuberculosis H37Rv using the in silico strain iNJ661 and proposing alternative drug targets. BMC Syst. Biol. 2007; 1: 26-46.
-
(2007)
BMC Syst. Biol.
, vol.1
, pp. 26-46
-
-
Jamshidi, N.1
Palsson, BØ.2
-
65
-
-
70049110173
-
Interpreting expression data with metabolic flux models: Predicting Mycobacterium tuberculosis mycolic acid production
-
Colijn C, Brandes A, Zucker J, et al. Interpreting expression data with metabolic flux models: predicting Mycobacterium tuberculosis mycolic acid production. PLoS Comput. Biol. 2009; 5: e1000489.
-
(2009)
PLoS Comput. Biol.
, vol.5
-
-
Colijn, C.1
Brandes, A.2
Zucker, J.3
-
66
-
-
67650433616
-
Modeling the immune rheostat of macrophages in the lung in response to infection
-
Day J, Friedman A, Schlesinger LS,. Modeling the immune rheostat of macrophages in the lung in response to infection. Proc. Natl Acad. Sci. U.S.A. 2009; 106: 11246-11251.
-
(2009)
Proc. Natl Acad. Sci. U.S.A.
, vol.106
, pp. 11246-11251
-
-
Day, J.1
Friedman, A.2
Schlesinger, L.S.3
-
67
-
-
77958518502
-
Mathematical modeling of tuberculosis bacillary counts and cellular populations in the organs of infected mice
-
Pai M. ed.
-
Bru A, Cardona P-J,. Mathematical modeling of tuberculosis bacillary counts and cellular populations in the organs of infected mice., Pai M, ed. PLoS ONE 2010; 5: e12985.
-
(2010)
PLoS ONE
, vol.5
-
-
Bru, A.1
Cardona, P.-J.2
-
68
-
-
22344448429
-
Properties and protective value of the secondary versus primary T helper type 1 response to airborne Mycobacterium tuberculosis infection in mice
-
Jung YJ,. Properties and protective value of the secondary versus primary T helper type 1 response to airborne Mycobacterium tuberculosis infection in mice. J. Exp. Med. 2005; 201: 1915-1924.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1915-1924
-
-
Jung, Y.J.1
-
69
-
-
77955478490
-
Identification of key processes that control tumor necrosis factor availability in a tuberculosis granuloma
-
Fallahi-Sichani M, Schaller MA, Kirschner DE, et al. Identification of key processes that control tumor necrosis factor availability in a tuberculosis granuloma. PLoS Comput. Biol. 2010; 6: e1000778.
-
(2010)
PLoS Comput. Biol.
, vol.6
-
-
Fallahi-Sichani, M.1
Schaller, M.A.2
Kirschner, D.E.3
-
71
-
-
79957777939
-
Systems biology approaches to new vaccine development
-
Oberg AL, Kennedy RB, Li P, et al. Systems biology approaches to new vaccine development. Curr. Opin. Immunol. 2011; 23: 436-443.
-
(2011)
Curr. Opin. Immunol.
, vol.23
, pp. 436-443
-
-
Oberg, A.L.1
Kennedy, R.B.2
Li, P.3
-
72
-
-
75149151920
-
Tuberculosis research: Going forward with a powerful Translational Systems Biology approach
-
Day J, Schlesinger LS, Friedman A,. Tuberculosis research: going forward with a powerful Translational Systems Biology approach. Tuberculosis 2010; 90: 7-8.
-
(2010)
Tuberculosis
, vol.90
, pp. 7-8
-
-
Day, J.1
Schlesinger, L.S.2
Friedman, A.3
-
73
-
-
80052776804
-
The top five 'game changers' in vaccinology: Toward rational and directed vaccine development
-
Kennedy RB, Poland GA,. The top five 'game changers' in vaccinology: toward rational and directed vaccine development. OMICS 2011; 15: 533-537.
-
(2011)
OMICS
, vol.15
, pp. 533-537
-
-
Kennedy, R.B.1
Poland, G.A.2
-
74
-
-
80052599857
-
Vaccinomics: Current findings, challenges and novel approaches for vaccine development
-
Ovsyannikova IG, Poland GA,. Vaccinomics: current findings, challenges and novel approaches for vaccine development. AAPS J. 2011; 13: 438-444.
-
(2011)
AAPS J.
, vol.13
, pp. 438-444
-
-
Ovsyannikova, I.G.1
Poland, G.A.2
-
75
-
-
57849085182
-
Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans
-
Querec TD, Akondy RS, Lee EK, et al. Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans. Nat. Immunol. 2008; 10: 116-125.
-
(2008)
Nat. Immunol.
, vol.10
, pp. 116-125
-
-
Querec, T.D.1
Akondy, R.S.2
Lee, E.K.3
-
76
-
-
59649129816
-
Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses
-
Gaucher D, Therrien R, Kettaf N, et al. Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses. J. Exp. Med. 2008; 205: 3119-3131.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 3119-3131
-
-
Gaucher, D.1
Therrien, R.2
Kettaf, N.3
-
77
-
-
33646199047
-
Heparin-binding hemagglutinin, from an extrapulmonary dissemination factor to a powerful diagnostic and protective antigen against tuberculosis
-
Locht C, Hougardy J-M, Rouanet C, et al. Heparin-binding hemagglutinin, from an extrapulmonary dissemination factor to a powerful diagnostic and protective antigen against tuberculosis. Tuberculosis 2006; 86: 303-309.
-
(2006)
Tuberculosis
, vol.86
, pp. 303-309
-
-
Locht, C.1
Hougardy, J.-M.2
Rouanet, C.3
-
78
-
-
77955894773
-
An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
-
Berry MPR, Graham CM, McNab FW, et al. An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature 2010; 466: 973-977.
-
(2010)
Nature
, vol.466
, pp. 973-977
-
-
Berry, M.P.R.1
Graham, C.M.2
McNab, F.W.3
-
79
-
-
77956220982
-
Mycobacterium bovis-BCG vaccination induces specific pulmonary transcriptome biosignatures in mice
-
Aranday Cortes E, Kaveh D, Nunez-Garcia J, et al. Mycobacterium bovis-BCG vaccination induces specific pulmonary transcriptome biosignatures in mice. PLoS ONE 2010; 5: e11319.
-
(2010)
PLoS ONE
, vol.5
-
-
Aranday Cortes, E.1
Kaveh, D.2
Nunez-Garcia, J.3
-
80
-
-
59449085932
-
Comprehensive gene expression profiling in lungs of mice infected with Mycobacterium tuberculosis following DNAhsp65 immunotherapy
-
Zárate-Bladés CR, Bonato VLD, da Silveira ELV, et al. Comprehensive gene expression profiling in lungs of mice infected with Mycobacterium tuberculosis following DNAhsp65 immunotherapy. J. Gene Med. 2009; 11: 66-78.
-
(2009)
J. Gene Med.
, vol.11
, pp. 66-78
-
-
Zárate-Bladés, C.R.1
Bonato, V.L.D.2
Da Silveira, E.L.V.3
-
81
-
-
84861921478
-
In silico identification of potential antigenic proteins and promiscuous CTL epitopes in Mycobacterium tuberculosis
-
Sundaramurthi JC, Brindha S, Shobitha SR, et al. In silico identification of potential antigenic proteins and promiscuous CTL epitopes in Mycobacterium tuberculosis. Infect. Genet. Evol. 2012; 12: 1312-1318.
-
(2012)
Infect. Genet. Evol.
, vol.12
, pp. 1312-1318
-
-
Sundaramurthi, J.C.1
Brindha, S.2
Shobitha, S.R.3
-
82
-
-
84858718283
-
Creativity in tuberculosis research and discovery
-
Young D, Verreck FAW,. Creativity in tuberculosis research and discovery. Tuberculosis (Edinb) 2012; 92: S14-16.
-
(2012)
Tuberculosis (Edinb)
, vol.92
-
-
Young, D.1
Verreck, F.A.W.2
-
83
-
-
84858734201
-
Transforming biomedical research to develop effective TB vaccines: The next ten years
-
Sizemore CF, Fauci AS,. Transforming biomedical research to develop effective TB vaccines: the next ten years. Tuberculosis (Edinb) 2012; 92: S2-3.
-
(2012)
Tuberculosis (Edinb)
, vol.92
-
-
Sizemore, C.F.1
Fauci, A.S.2
|