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Volumn 13, Issue SUPPL. 3, 2008, Pages

Immunopathogenesis of tuberculosis: Implications for vaccine development

Author keywords

Immunology; Pathogenesis; Tuberculosis; Vaccine

Indexed keywords

ACID PHOSPHATASE; AERAS 402; AERAS 404; BCG VACCINE; CD4 ANTIGEN; COMPLEMENT RECEPTOR; DNA VACCINE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 23; INTERLEUKIN 4; INTERLEUKIN 7; LIPOARABINOMANNAN; LISTERIOLYSIN; LIVE VACCINE; MANNOSE RECEPTOR; MVA 85 A; MYCOBACTERIUM ANTIGEN; NUCLEIC ACID; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PROTEIN CR 3; RECOMBINANT VACCINE; SCAVENGER RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VACCINIA VACCINE;

EID: 49749093396     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/j.1440-1843.2008.01350.x     Document Type: Conference Paper
Times cited : (5)

References (51)
  • 1
    • 49749129041 scopus 로고    scopus 로고
    • World Health Organization. World Health Organization Tuberculosis (TB). Accessed April 17 2007.] Available from URL
    • World Health Organization. World Health Organization Tuberculosis (TB) Accessed April 17 2007.] Available from URL: http://wwwwhoint/tb/en/
  • 2
    • 49749148601 scopus 로고    scopus 로고
    • World Health Organization. XDR-TB, extensively drug-resistant tuberculosis. Accessed 5 Dec 2006.] Available from URL
    • World Health Organization. XDR-TB, extensively drug-resistant tuberculosis Accessed 5 Dec 2006.] Available from URL: http://www.who.int/ mediacentre/news/notes/2006/np23/en/index.html
  • 3
    • 0027411682 scopus 로고
    • Exogenous reinfection with multidrug-resistant Mycobacterium tuberculosis in patients with advanced HIV infection
    • Small PM, Shafer RW, Hopewell PC, Singh SP, Murphy MJ et al. Exogenous reinfection with multidrug-resistant Mycobacterium tuberculosis in patients with advanced HIV infection. N. Engl. J. Med. 1993 328: 1137 44.
    • (1993) N. Engl. J. Med. , vol.328 , pp. 1137-44
    • Small, P.M.1    Shafer, R.W.2    Hopewell, P.C.3    Singh, S.P.4    Murphy, M.J.5
  • 4
    • 2442711824 scopus 로고    scopus 로고
    • Persistent and dormant tubercle bacilli and latent tuberculosis
    • Zhang Y. Persistent and dormant tubercle bacilli and latent tuberculosis. Front. Biosci. 2004 9: 1136 56.
    • (2004) Front. Biosci. , vol.9 , pp. 1136-56
    • Zhang, Y.1
  • 7
    • 0025216480 scopus 로고
    • Phagocytosis of Mycobacterium tuberculosis is mediated by human monocyte complement receptors and complement component C3
    • Schlesinger LS, Bellinger-Kawahara CG, Payne NR, Horwitz MA. Phagocytosis of Mycobacterium tuberculosis is mediated by human monocyte complement receptors and complement component C3. J. Immunol. 1990 144: 2771 80.
    • (1990) J. Immunol. , vol.144 , pp. 2771-80
    • Schlesinger, L.S.1    Bellinger-Kawahara, C.G.2    Payne, N.R.3    Horwitz, M.A.4
  • 8
    • 0032037616 scopus 로고    scopus 로고
    • Macrophage receptors for Mycobacterium tuberculosis
    • Ernst JD. Macrophage receptors for Mycobacterium tuberculosis. Infect. Immun. 1998 66: 1277 81.
    • (1998) Infect. Immun. , vol.66 , pp. 1277-81
    • Ernst, J.D.1
  • 9
    • 15244340430 scopus 로고    scopus 로고
    • Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis
    • Vergne I, Chua J, Lee HH, Lucas M, Belisle J et al. Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. USA 2005 102: 4033 8.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 4033-8
    • Vergne, I.1    Chua, J.2    Lee, H.H.3    Lucas, M.4    Belisle, J.5
  • 10
    • 2942718724 scopus 로고    scopus 로고
    • Protein kinase G from pathogenic mycobacteria promotes survival within macrophages
    • Walburger A, Koul A, Ferrari G, Nguyen L, Prescianotto-Baschong C et al. Protein kinase G from pathogenic mycobacteria promotes survival within macrophages. Science 2004 304: 1800 4.
    • (2004) Science , vol.304 , pp. 1800-4
    • Walburger, A.1    Koul, A.2    Ferrari, G.3    Nguyen, L.4    Prescianotto-Baschong, C.5
  • 11
    • 0037627408 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest
    • Fratti RA, Chua J, Vergne I, Deretic V. Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest. Proc. Natl. Acad. Sci. USA 2003 100: 5437 42.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 5437-42
    • Fratti, R.A.1    Chua, J.2    Vergne, I.3    Deretic, V.4
  • 12
    • 33745855871 scopus 로고    scopus 로고
    • Autophagy in immune defense against Mycobacterium tuberculosis
    • Vergne I, Singh S, Roberts E, Kyei G, Master S et al. Autophagy in immune defense against Mycobacterium tuberculosis. Autophagy 2006 2: 175 8.
    • (2006) Autophagy , vol.2 , pp. 175-8
    • Vergne, I.1    Singh, S.2    Roberts, E.3    Kyei, G.4    Master, S.5
  • 13
    • 33748506089 scopus 로고    scopus 로고
    • Human IRGM induces autophagy to eliminate intracellular mycobacteria
    • Singh SB, Davis AS, Taylor GA, Deretic V. Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science 2006 313: 1438 41.
    • (2006) Science , vol.313 , pp. 1438-41
    • Singh, S.B.1    Davis, A.S.2    Taylor, G.A.3    Deretic, V.4
  • 14
    • 0142240338 scopus 로고    scopus 로고
    • Immune control of tuberculosis by IFN-gamma-inducible LRG-47
    • MacMicking JD, Taylor GA, McKinney JD. Immune control of tuberculosis by IFN-gamma-inducible LRG-47. Science 2003 302: 654 9.
    • (2003) Science , vol.302 , pp. 654-9
    • MacMicking, J.D.1    Taylor, G.A.2    McKinney, J.D.3
  • 15
    • 10944253145 scopus 로고    scopus 로고
    • Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
    • Gutierrez MG, Master SS, Singh SB, Taylor GA, Colombo MI et al. Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 2004 119: 753 66.
    • (2004) Cell , vol.119 , pp. 753-66
    • Gutierrez, M.G.1    Master, S.S.2    Singh, S.B.3    Taylor, G.A.4    Colombo, M.I.5
  • 16
    • 34548700401 scopus 로고    scopus 로고
    • T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis
    • Harris J, De Haro SA, Master SS, Keane J, Roberts EA et al. T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis. Immunity 2007 27: 505 17.
    • (2007) Immunity , vol.27 , pp. 505-17
    • Harris, J.1    De Haro, S.A.2    Master, S.S.3    Keane, J.4    Roberts, E.A.5
  • 17
    • 34250222782 scopus 로고    scopus 로고
    • Host innate immune response to Mycobacterium tuberculosis
    • Bhatt K, Salgame P. Host innate immune response to Mycobacterium tuberculosis. J. Clin. Immunol. 2007 27: 347 62.
    • (2007) J. Clin. Immunol. , vol.27 , pp. 347-62
    • Bhatt, K.1    Salgame, P.2
  • 18
    • 33645224419 scopus 로고    scopus 로고
    • Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response
    • Liu PT, Stenger S, Li H, Wenzel L, Tan BH et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 2006 311: 1770 3.
    • (2006) Science , vol.311 , pp. 1770-3
    • Liu, P.T.1    Stenger, S.2    Li, H.3    Wenzel, L.4    Tan, B.H.5
  • 19
    • 33749476080 scopus 로고    scopus 로고
    • Exploiting immunology and molecular genetics for rational vaccine design against tuberculosis
    • Kaufmann SH, Baumann S, Nasser Eddine A. Exploiting immunology and molecular genetics for rational vaccine design against tuberculosis. Int. J. Tuberc. Lung Dis. 2006 10: 1068 79.
    • (2006) Int. J. Tuberc. Lung Dis. , vol.10 , pp. 1068-79
    • Kaufmann, S.H.1    Baumann, S.2    Nasser Eddine, A.3
  • 20
    • 33645109281 scopus 로고    scopus 로고
    • A role for CD4+CD25+ T cells in regulation of the immune response during human tuberculosis
    • Ribeiro-Rodrigues R, Resende Co T, Rojas R, Toossi Z, Dietze R et al. A role for CD4+CD25+ T cells in regulation of the immune response during human tuberculosis. Clin. Exp. Immunol. 2006 144: 25 34.
    • (2006) Clin. Exp. Immunol. , vol.144 , pp. 25-34
    • Ribeiro-Rodrigues, R.1    Resende Co, T.2    Rojas, R.3    Toossi, Z.4    Dietze, R.5
  • 22
    • 34248667663 scopus 로고    scopus 로고
    • Th2 cytokines in susceptibility to tuberculosis
    • Rook GA. Th2 cytokines in susceptibility to tuberculosis. Curr. Mol. Med. 2007 7: 327 37.
    • (2007) Curr. Mol. Med. , vol.7 , pp. 327-37
    • Rook, G.A.1
  • 23
    • 42249084604 scopus 로고    scopus 로고
    • Mannose-capped lipoarabinomannan- and prostaglandin E2-dependent expansion of regulatory T cells in human Mycobacterium tuberculosis infection
    • Garg A, Barnes PF, Roy S, Quiroga MF, Wu S et al. Mannose-capped lipoarabinomannan- and prostaglandin E2-dependent expansion of regulatory T cells in human Mycobacterium tuberculosis infection. Eur. J. Immunol. 2008 38: 459 69.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 459-69
    • Garg, A.1    Barnes, P.F.2    Roy, S.3    Quiroga, M.F.4    Wu, S.5
  • 24
    • 34248562792 scopus 로고    scopus 로고
    • IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge
    • Khader SA, Bell GK, Pearl JE, Fountain JJ, Rangel-Moreno J et al. IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat. Immunol. 2007 8: 369 77.
    • (2007) Nat. Immunol. , vol.8 , pp. 369-77
    • Khader, S.A.1    Bell, G.K.2    Pearl, J.E.3    Fountain, J.J.4    Rangel-Moreno, J.5
  • 25
    • 33746215298 scopus 로고    scopus 로고
    • Cutting edge: IFN-gamma regulates the induction and expansion of IL-17-producing CD4 T cells during mycobacterial infection
    • Cruz A, Khader SA, Torrado E, Fraga A, Pearl JE et al. Cutting edge: IFN-gamma regulates the induction and expansion of IL-17-producing CD4 T cells during mycobacterial infection. J. Immunol. 2006 177: 1416 20.
    • (2006) J. Immunol. , vol.177 , pp. 1416-20
    • Cruz, A.1    Khader, S.A.2    Torrado, E.3    Fraga, A.4    Pearl, J.E.5
  • 26
    • 33646822975 scopus 로고    scopus 로고
    • Advances in tuberculosis vaccine strategies
    • Skeiky YA, Sadoff JC. Advances in tuberculosis vaccine strategies. Nat. Rev. Microbiol. 2006 4: 469 76.
    • (2006) Nat. Rev. Microbiol. , vol.4 , pp. 469-76
    • Skeiky, Y.A.1    Sadoff, J.C.2
  • 27
    • 0028872014 scopus 로고
    • Variation in protection by BCG: Implications of and for heterologous immunity
    • Fine PE. Variation in protection by BCG: implications of and for heterologous immunity. Lancet 1995 346: 1339 45.
    • (1995) Lancet , vol.346 , pp. 1339-45
    • Fine, P.E.1
  • 28
    • 34250163887 scopus 로고    scopus 로고
    • BCG vaccination confers poor protection against M. tuberculosis HN878-induced central nervous system disease
    • Tsenova L, Harbacheuski R, Sung N, Ellison E, Fallows D et al. BCG vaccination confers poor protection against M. tuberculosis HN878-induced central nervous system disease. Vaccine 2007 25: 5126 32.
    • (2007) Vaccine , vol.25 , pp. 5126-32
    • Tsenova, L.1    Harbacheuski, R.2    Sung, N.3    Ellison, E.4    Fallows, D.5
  • 29
    • 34447291089 scopus 로고    scopus 로고
    • Chronic helminth infections may negatively influence immunity against tuberculosis and other diseases of public health importance
    • Elias D, Britton S, Kassu A, Akuffo H. Chronic helminth infections may negatively influence immunity against tuberculosis and other diseases of public health importance. Expert Rev. Anti. Infect. Ther. 2007 5: 475 84.
    • (2007) Expert Rev. Anti. Infect. Ther. , vol.5 , pp. 475-84
    • Elias, D.1    Britton, S.2    Kassu, A.3    Akuffo, H.4
  • 30
    • 32944466277 scopus 로고    scopus 로고
    • The development and impact of tuberculosis vaccines
    • Young D, Dye C. The development and impact of tuberculosis vaccines. Cell 2006 124: 683 7.
    • (2006) Cell , vol.124 , pp. 683-7
    • Young, D.1    Dye, C.2
  • 31
    • 20144389346 scopus 로고    scopus 로고
    • Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis
    • Williams A, Hatch GJ, Clark SO, Gooch KE, Hatch KA et al. Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis. Tuberculosis (Edinb) 2005 85: 29 38.
    • (2005) Tuberculosis (Edinb) , vol.85 , pp. 29-38
    • Williams, A.1    Hatch, G.J.2    Clark, S.O.3    Gooch, K.E.4    Hatch, K.A.5
  • 32
    • 22344433382 scopus 로고    scopus 로고
    • Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guerin mutants that secrete listeriolysin
    • Grode L, Seiler P, Baumann S, Hess J, Brinkmann V et al. Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guerin mutants that secrete listeriolysin. J. Clin. Invest. 2005 115: 2472 9.
    • (2005) J. Clin. Invest. , vol.115 , pp. 2472-9
    • Grode, L.1    Seiler, P.2    Baumann, S.3    Hess, J.4    Brinkmann, V.5
  • 33
    • 20444448766 scopus 로고    scopus 로고
    • Live attenuated mutants of Mycobacterium tuberculosis as candidate vaccines against tuberculosis
    • Sambandamurthy VK, Jacobs WR, Jr. Live attenuated mutants of Mycobacterium tuberculosis as candidate vaccines against tuberculosis. Microbes Infect. 2005 7: 955 61.
    • (2005) Microbes Infect. , vol.7 , pp. 955-61
    • Sambandamurthy, V.K.1    Jacobs Jr., W.R.2
  • 35
    • 33344476825 scopus 로고    scopus 로고
    • Immunogenicity and protection induced by Mycobacterium tuberculosis mce-2 and mce-3 mutants in a Balb/c mouse model of progressive pulmonary tuberculosis
    • Aguilar LD, Infante E, Bianco MV, Cataldi A, Bigi F et al. Immunogenicity and protection induced by Mycobacterium tuberculosis mce-2 and mce-3 mutants in a Balb/c mouse model of progressive pulmonary tuberculosis. Vaccine 2006 24: 2333 42.
    • (2006) Vaccine , vol.24 , pp. 2333-42
    • Aguilar, L.D.1    Infante, E.2    Bianco, M.V.3    Cataldi, A.4    Bigi, F.5
  • 36
  • 37
    • 26844521205 scopus 로고    scopus 로고
    • Recent advances in the development of adenovirus- and poxvirus-vectored tuberculosis vaccines
    • Xing Z, Santosuosso M, McCormick S, Yang TC, Millar J et al. Recent advances in the development of adenovirus- and poxvirus-vectored tuberculosis vaccines. Curr. Gene Ther. 2005 5: 485 92.
    • (2005) Curr. Gene Ther. , vol.5 , pp. 485-92
    • Xing, Z.1    Santosuosso, M.2    McCormick, S.3    Yang, T.C.4    Millar, J.5
  • 39
    • 36248967655 scopus 로고    scopus 로고
    • Immunisation with BCG and recombinant MVA85A induces long-lasting, polyfunctional Mycobacterium tuberculosis-specific CD4+ memory T lymphocyte populations
    • Beveridge NE, Price DA, Casazza JP, Pathan AA, Sander CR et al. Immunisation with BCG and recombinant MVA85A induces long-lasting, polyfunctional Mycobacterium tuberculosis-specific CD4+ memory T lymphocyte populations. Eur. J. Immunol. 2007 37: 3089 100.
    • (2007) Eur. J. Immunol. , vol.37 , pp. 3089-100
    • Beveridge, N.E.1    Price, D.A.2    Casazza, J.P.3    Pathan, A.A.4    Sander, C.R.5
  • 40
    • 0030898789 scopus 로고    scopus 로고
    • The potential of the ESAT-6 antigen secreted by virulent mycobacteria for specific diagnosis of tuberculosis
    • Pollock JM, Andersen P. The potential of the ESAT-6 antigen secreted by virulent mycobacteria for specific diagnosis of tuberculosis. J. Infect. Dis. 1997 175: 1251 4.
    • (1997) J. Infect. Dis. , vol.175 , pp. 1251-4
    • Pollock, J.M.1    Andersen, P.2
  • 41
    • 26244458713 scopus 로고    scopus 로고
    • Effect of BCG revaccination on incidence of tuberculosis in school-aged children in Brazil: The BCG-REVAC cluster-randomised trial
    • Rodrigues LC, Pereira SM, Cunha SS, Genser B, Ichihara MY et al. Effect of BCG revaccination on incidence of tuberculosis in school-aged children in Brazil: the BCG-REVAC cluster-randomised trial. Lancet 2005 366: 1290 5.
    • (2005) Lancet , vol.366 , pp. 1290-5
    • Rodrigues, L.C.1    Pereira, S.M.2    Cunha, S.S.3    Genser, B.4    Ichihara, M.Y.5
  • 42
    • 34248666108 scopus 로고    scopus 로고
    • The Ag85B protein of Mycobacterium tuberculosis may turn a protective immune response induced by Ag85B-DNA vaccine into a potent but non-protective Th1 immune response in mice
    • Palma C, Iona E, Giannoni F, Pardini M, Brunori L et al. The Ag85B protein of Mycobacterium tuberculosis may turn a protective immune response induced by Ag85B-DNA vaccine into a potent but non-protective Th1 immune response in mice. Cell. Microbiol. 2007 9: 1455 65.
    • (2007) Cell. Microbiol. , vol.9 , pp. 1455-65
    • Palma, C.1    Iona, E.2    Giannoni, F.3    Pardini, M.4    Brunori, L.5
  • 43
    • 33745219834 scopus 로고    scopus 로고
    • Immunogenicity and protective efficacy of tuberculosis DNA vaccines combining mycolyl-transferase Ag85A and phosphate transport receptor PstS-3
    • Romano M, Roupie V, Wang XM, Denis O, Jurion F et al. Immunogenicity and protective efficacy of tuberculosis DNA vaccines combining mycolyl-transferase Ag85A and phosphate transport receptor PstS-3. Immunology 2006 118: 321 32.
    • (2006) Immunology , vol.118 , pp. 321-32
    • Romano, M.1    Roupie, V.2    Wang, X.M.3    Denis, O.4    Jurion, F.5
  • 44
    • 34250361033 scopus 로고    scopus 로고
    • Next generation: Tuberculosis vaccines that elicit protective CD8+ T cells
    • Behar SM, Woodworth JS, Wu Y. Next generation: tuberculosis vaccines that elicit protective CD8+ T cells. Expert Rev. Vaccines 2007 6: 441 56.
    • (2007) Expert Rev. Vaccines , vol.6 , pp. 441-56
    • Behar, S.M.1    Woodworth, J.S.2    Wu, Y.3
  • 45
    • 33744815623 scopus 로고    scopus 로고
    • Protective immunity to tuberculosis with Ag85B-ESAT-6 in a synthetic cationic adjuvant system IC31
    • Agger EM, Rosenkrands I, Olsen AW, Hatch G, Williams A et al. Protective immunity to tuberculosis with Ag85B-ESAT-6 in a synthetic cationic adjuvant system IC31. Vaccine 2006 24: 5452 60.
    • (2006) Vaccine , vol.24 , pp. 5452-60
    • Agger, E.M.1    Rosenkrands, I.2    Olsen, A.W.3    Hatch, G.4    Williams, A.5
  • 46
    • 35349028297 scopus 로고    scopus 로고
    • GlaxoSmithKline adjuvant systems in vaccines: Concepts, achievements and perspectives
    • Garcon N, Chomez P, Van Mechelen M. GlaxoSmithKline adjuvant systems in vaccines: concepts, achievements and perspectives. Expert Rev. Vaccines 2007 6: 723 39.
    • (2007) Expert Rev. Vaccines , vol.6 , pp. 723-39
    • Garcon, N.1    Chomez, P.2    Van Mechelen, M.3
  • 47
    • 0038751936 scopus 로고    scopus 로고
    • Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis
    • Pym AS, Brodin P, Majlessi L, Brosch R, Demangel C et al. Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis. Nat. Med. 2003 9: 533 9.
    • (2003) Nat. Med. , vol.9 , pp. 533-9
    • Pym, A.S.1    Brodin, P.2    Majlessi, L.3    Brosch, R.4    Demangel, C.5
  • 48
    • 0042140672 scopus 로고    scopus 로고
    • Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis dormancy program
    • Voskuil MI, Schnappinger D, Visconti KC, Harrell MI, Dolganov GM et al. Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis dormancy program. J. Exp. Med. 2003 198: 705 13.
    • (2003) J. Exp. Med. , vol.198 , pp. 705-13
    • Voskuil, M.I.1    Schnappinger, D.2    Visconti, K.C.3    Harrell, M.I.4    Dolganov, G.M.5
  • 49
    • 33845917536 scopus 로고    scopus 로고
    • Vaccine strategies against latent tuberculosis infection
    • Andersen P. Vaccine strategies against latent tuberculosis infection. Trends Microbiol. 2007 15: 7 13.
    • (2007) Trends Microbiol. , vol.15 , pp. 7-13
    • Andersen, P.1


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