A DNA vaccine expressing CFP21 and MPT64 fusion protein enhances BCG-induced protective immunity against Mycobacterium tuberculosis infection in mice

Medical Microbiology and Immunology

Volumn 200, Issue 3, 2011, Pages 165-175

  Wang, Chun ^a   Chen, Zhenhua ^a   Fu, Ruiling ^a   Zhang, Ying ^b   Chen, Lingxia ^a   Huang, Li ^a   Li, Jinjin ^a   Shi, Chunwei ^a   Fan, Xionglin ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

BCG; DNA vaccine; Mycobacterium tuberculosis; Prime boost strategy; Tuberculosis

Indexed keywords

BCG VACCINE; DNA VACCINE; GAMMA INTERFERON; HYBRID PROTEIN; PROTEIN CFP21; PROTEIN MPT64; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL IMMUNITY; BACTERIAL LOAD; BACTERIAL VIRULENCE; C57BL 6 MOUSE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; FEMALE; HUMAN; LUNG PARENCHYMA; LUNG TUBERCULOSIS; MALE; MONOTHERAPY; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; POPULATION RESEARCH; PRIORITY JOURNAL; TUBERCULIN TEST;

ADULT; ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL LOAD; BACTERIAL PROTEINS; BCG VACCINE; CELLS, CULTURED; CLONING, MOLECULAR; ESCHERICHIA COLI; FEMALE; HUMANS; IMMUNIZATION, SECONDARY; IMMUNOGLOBULIN G; INTERFERON-GAMMA; LUNG; MALE; MICE; MICE, INBRED C57BL; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; PLASMIDS; RECOMBINANT FUSION PROTEINS; SPLEEN; TUBERCULIN TEST; TUBERCULOSIS; TUBERCULOSIS VACCINES; VACCINES, DNA; YOUNG ADULT;

EID: 79961208433     PISSN: 03008584     EISSN: 14321831     Source Type: Journal    
DOI: 10.1007/s00430-011-0188-z     Document Type: Article

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