-
1
-
-
84863308390
-
Pink1 and its {Delta}psi-dependent cleavage product both localize to the outer mitochondrial membrane by a unique targeting mode
-
Becker D., Richter J., et al. Pink1 and its {Delta}psi-dependent cleavage product both localize to the outer mitochondrial membrane by a unique targeting mode. J. Biol. Chem. 2012.
-
(2012)
J. Biol. Chem.
-
-
Becker, D.1
Richter, J.2
-
2
-
-
33646375711
-
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
-
Bender A., Krishnan K.J., et al. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease. Nat. Genet. 2006, 38(5):515-517.
-
(2006)
Nat. Genet.
, vol.38
, Issue.5
, pp. 515-517
-
-
Bender, A.1
Krishnan, K.J.2
-
3
-
-
27944504351
-
P62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
-
Bjorkoy G., Lamark T., et al. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J. Cell Biol. 2005, 171(4):603-614.
-
(2005)
J. Cell Biol.
, vol.171
, Issue.4
, pp. 603-614
-
-
Bjorkoy, G.1
Lamark, T.2
-
4
-
-
36448932411
-
Expression of PINK1 mRNA in human and rodent brain and in Parkinson's disease
-
Blackinton J.G., Anvret A., et al. Expression of PINK1 mRNA in human and rodent brain and in Parkinson's disease. Brain Res. 2007, 1184:10-16.
-
(2007)
Brain Res.
, vol.1184
, pp. 10-16
-
-
Blackinton, J.G.1
Anvret, A.2
-
5
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
Bonifati V., Rizzu P., et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 2003, 299(5604):256-259.
-
(2003)
Science
, vol.299
, Issue.5604
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
-
6
-
-
84858701257
-
Spatial Parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons
-
Cai Q., Zakaria H.M., et al. Spatial Parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons. Curr. Biol. 2012, 22(6):545-552.
-
(2012)
Curr. Biol.
, vol.22
, Issue.6
, pp. 545-552
-
-
Cai, Q.1
Zakaria, H.M.2
-
7
-
-
77951096150
-
Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
-
Chen H., Chan D.C. Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases. Hum. Mol. Genet. 2009, 18(R2):R169-R176.
-
(2009)
Hum. Mol. Genet.
, vol.18
, Issue.R2
-
-
Chen, H.1
Chan, D.C.2
-
8
-
-
33745589773
-
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
-
Clark I.E., Dodson M.W., et al. Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 2006, 441(7097):1162-1166.
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1162-1166
-
-
Clark, I.E.1
Dodson, M.W.2
-
9
-
-
0033042094
-
Novel effects of FCCP [carbonyl cyanide p-(trifluoromethoxy)phenylhydrazone] on amyloid precursor protein processing
-
Connop B.P., Thies R.L., et al. Novel effects of FCCP [carbonyl cyanide p-(trifluoromethoxy)phenylhydrazone] on amyloid precursor protein processing. J. Neurochem. 1999, 72(4):1457-1465.
-
(1999)
J. Neurochem.
, vol.72
, Issue.4
, pp. 1457-1465
-
-
Connop, B.P.1
Thies, R.L.2
-
10
-
-
0442323561
-
Autophagy: in sickness and in health
-
Cuervo A.M. Autophagy: in sickness and in health. Trends Cell Biol. 2004, 14:70-77.
-
(2004)
Trends Cell Biol.
, vol.14
, pp. 70-77
-
-
Cuervo, A.M.1
-
11
-
-
77951235489
-
Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1
-
Cui M., Tang X., et al. Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1. J. Biol. Chem. 2010, 285(15):11740-11752.
-
(2010)
J. Biol. Chem.
, vol.285
, Issue.15
, pp. 11740-11752
-
-
Cui, M.1
Tang, X.2
-
12
-
-
79956278232
-
Silencing of PINK1 induces mitophagy via mitochondrial permeability transition in dopaminergic MN9D cells
-
Cui T., Fan C., et al. Silencing of PINK1 induces mitophagy via mitochondrial permeability transition in dopaminergic MN9D cells. Brain Res. 2011, 1394:1-13.
-
(2011)
Brain Res.
, vol.1394
, pp. 1-13
-
-
Cui, T.1
Fan, C.2
-
13
-
-
67649399288
-
Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission
-
Dagda R.K., Cherra S.J., et al. Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission. J. Biol. Chem. 2009, 284(20):13843-13855.
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.20
, pp. 13843-13855
-
-
Dagda, R.K.1
Cherra, S.J.2
-
14
-
-
81155128499
-
Mitochondrially localized PKA reverses mitochondrial pathology and dysfunction in a cellular model of Parkinson's disease
-
Dagda R.K., Gusdon A.M., et al. Mitochondrially localized PKA reverses mitochondrial pathology and dysfunction in a cellular model of Parkinson's disease. Cell Death Differ. 2011, 18(12):1914-1923.
-
(2011)
Cell Death Differ.
, vol.18
, Issue.12
, pp. 1914-1923
-
-
Dagda, R.K.1
Gusdon, A.M.2
-
15
-
-
0037338634
-
Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death
-
Darios F., Corti O., et al. Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death. Hum. Mol. Genet. 2003, 12(5):517-526.
-
(2003)
Hum. Mol. Genet.
, vol.12
, Issue.5
, pp. 517-526
-
-
Darios, F.1
Corti, O.2
-
16
-
-
0141741347
-
Parkinson's disease: mechanisms and models
-
Dauer W., Przedborski S. Parkinson's disease: mechanisms and models. Neuron 2003, 39(6):889-909.
-
(2003)
Neuron
, vol.39
, Issue.6
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
17
-
-
33745919520
-
Epidemiology of Parkinson's disease
-
de Lau L.M., Breteler M.M. Epidemiology of Parkinson's disease. Lancet Neurol. 2006, 5(6):525-535.
-
(2006)
Lancet Neurol.
, vol.5
, Issue.6
, pp. 525-535
-
-
de Lau, L.M.1
Breteler, M.M.2
-
18
-
-
77956252454
-
Nix is critical to two distinct phases of mitophagy: reactive oxygen species (ROS)-mediated autophagy induction and Parkin-ubiqutin-p62-mediated mitochondria priming
-
Ding W.X., Ni H.M., et al. Nix is critical to two distinct phases of mitophagy: reactive oxygen species (ROS)-mediated autophagy induction and Parkin-ubiqutin-p62-mediated mitochondria priming. J. Biol. Chem. 2010, 285:27879-27890.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 27879-27890
-
-
Ding, W.X.1
Ni, H.M.2
-
19
-
-
36049038504
-
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin
-
Exner N., Treske B., et al. Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin. J. Neurosci. 2007, 27(45):12413-12418.
-
(2007)
J. Neurosci.
, vol.27
, Issue.45
, pp. 12413-12418
-
-
Exner, N.1
Treske, B.2
-
21
-
-
0021923437
-
Permeability change in transformed mouse fibroblasts caused by ionophores, and its relationship to membrane permeabilization by exogenous ATP
-
Friedberg I., Weisman G.A., et al. Permeability change in transformed mouse fibroblasts caused by ionophores, and its relationship to membrane permeabilization by exogenous ATP. J. Membr. Biol. 1985, 83(3):251-259.
-
(1985)
J. Membr. Biol.
, vol.83
, Issue.3
, pp. 251-259
-
-
Friedberg, I.1
Weisman, G.A.2
-
22
-
-
69149089036
-
Molecular pathogenesis of Parkinson disease: insights from genetic studies
-
Gasser T. Molecular pathogenesis of Parkinson disease: insights from genetic studies. Expert Rev. Mol. Med. 2009, 11:e22.
-
(2009)
Expert Rev. Mol. Med.
, vol.11
-
-
Gasser, T.1
-
23
-
-
78649463381
-
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
-
Gegg M.E., Cooper J.M., et al. Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy. Hum. Mol. Genet. 2010, 19:4861-4870.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 4861-4870
-
-
Gegg, M.E.1
Cooper, J.M.2
-
24
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
Geisler S., Holmstrom K.M., et al. PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat. Cell Biol. 2010, 12(2):119-131.
-
(2010)
Nat. Cell Biol.
, vol.12
, Issue.2
, pp. 119-131
-
-
Geisler, S.1
Holmstrom, K.M.2
-
25
-
-
84856951239
-
Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition
-
Gilkerson R.W., De Vries R.L., et al. Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition. Hum. Mol. Genet. 2012, 21(5):978-990.
-
(2012)
Hum. Mol. Genet.
, vol.21
, Issue.5
, pp. 978-990
-
-
Gilkerson, R.W.1
De Vries, R.L.2
-
26
-
-
79960493052
-
Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1
-
Glauser L., Sonnay S., et al. Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1. J. Neurochem. 2011, 118(4):636-645.
-
(2011)
J. Neurochem.
, vol.118
, Issue.4
, pp. 636-645
-
-
Glauser, L.1
Sonnay, S.2
-
27
-
-
84859428688
-
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
-
Greene A.W., Grenier K., et al. Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment. EMBO Rep. 2012, 13(4):378-385.
-
(2012)
EMBO Rep.
, vol.13
, Issue.4
, pp. 378-385
-
-
Greene, A.W.1
Grenier, K.2
-
28
-
-
84857850213
-
Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy
-
(Mar 15)
-
Itakura E., Kishi-Itakura C., et al. Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy. J. Cell Sci. 2012, 125(Pt 6):1488-1499. (Mar 15).
-
(2012)
J. Cell Sci.
, vol.125
, Issue.PART 6
, pp. 1488-1499
-
-
Itakura, E.1
Kishi-Itakura, C.2
-
29
-
-
78649685455
-
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
-
Jin S.M., Lazarou M., et al. Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL. J. Cell Biol. 2010, 191(5):933-942.
-
(2010)
J. Cell Biol.
, vol.191
, Issue.5
, pp. 933-942
-
-
Jin, S.M.1
Lazarou, M.2
-
30
-
-
67650264633
-
Atg32 is a mitochondrial protein that confers selectivity during mitophagy
-
Kanki T., Wang K., et al. Atg32 is a mitochondrial protein that confers selectivity during mitophagy. Dev. Cell 2009, 17(1):98-109.
-
(2009)
Dev. Cell
, vol.17
, Issue.1
, pp. 98-109
-
-
Kanki, T.1
Wang, K.2
-
31
-
-
77950371695
-
PINK1 is recruited to mitochondria with Parkin and associates with LC3 in mitophagy
-
Kawajiri S., Saiki S., et al. PINK1 is recruited to mitochondria with Parkin and associates with LC3 in mitophagy. FEBS Lett. 2010, 584:1073-1079.
-
(2010)
FEBS Lett.
, vol.584
, pp. 1073-1079
-
-
Kawajiri, S.1
Saiki, S.2
-
32
-
-
56049091236
-
PINK1 controls mitochondrial localization of Parkin through direct phosphorylation
-
Kim Y., Park J., et al. PINK1 controls mitochondrial localization of Parkin through direct phosphorylation. Biochem. Biophys. Res. Commun. 2008, 377(3):975-980.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.377
, Issue.3
, pp. 975-980
-
-
Kim, Y.1
Park, J.2
-
33
-
-
0032499264
-
Mutations in the Parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T., Asakawa S., et al. Mutations in the Parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998, 392(6676):605-608.
-
(1998)
Nature
, vol.392
, Issue.6676
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
-
34
-
-
77956173466
-
The molecular machinery of autophagy and its role in physiology and disease
-
Klionsky D.J. The molecular machinery of autophagy and its role in physiology and disease. Semin. Cell Dev. Biol. 2010.
-
(2010)
Semin. Cell Dev. Biol.
-
-
Klionsky, D.J.1
-
35
-
-
36849089101
-
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
-
Komatsu M., Waguri S., et al. Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell 2007, 131(6):1149-1163.
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1149-1163
-
-
Komatsu, M.1
Waguri, S.2
-
36
-
-
17144459368
-
Parkin expression in the developing mouse
-
Kuhn K., Zhu X.R., et al. Parkin expression in the developing mouse. Brain Res. Dev. Brain Res. 2004, 149(2):131-142.
-
(2004)
Brain Res. Dev. Brain Res.
, vol.149
, Issue.2
, pp. 131-142
-
-
Kuhn, K.1
Zhu, X.R.2
-
37
-
-
84857032953
-
Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin
-
Lazarou M., Jin S.M., et al. Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin. Dev. Cell 2012, 22(2):320-333.
-
(2012)
Dev. Cell
, vol.22
, Issue.2
, pp. 320-333
-
-
Lazarou, M.1
Jin, S.M.2
-
38
-
-
77952326081
-
Disease-causing mutations in Parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy
-
Lee J.Y., Nagano Y., et al. Disease-causing mutations in Parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy. J. Cell Biol. 2010, 189(4):671-679.
-
(2010)
J. Cell Biol.
, vol.189
, Issue.4
, pp. 671-679
-
-
Lee, J.Y.1
Nagano, Y.2
-
39
-
-
67650868959
-
Mitochondrial dynamics in mammalian health and disease
-
Liesa M., Palacin M., et al. Mitochondrial dynamics in mammalian health and disease. Physiol. Rev. 2009, 89(3):799-845.
-
(2009)
Physiol. Rev.
, vol.89
, Issue.3
, pp. 799-845
-
-
Liesa, M.1
Palacin, M.2
-
40
-
-
45249112594
-
Characterization of PINK1 processing, stability, and subcellular localization
-
Lin W., Kang U.J. Characterization of PINK1 processing, stability, and subcellular localization. J. Neurochem. 2008, 106(1):464-474.
-
(2008)
J. Neurochem.
, vol.106
, Issue.1
, pp. 464-474
-
-
Lin, W.1
Kang, U.J.2
-
41
-
-
78650694150
-
Reduction of protein translation and activation of autophagy protect against PINK1 pathogenesis in Drosophila melanogaster
-
Liu S., Lu B. Reduction of protein translation and activation of autophagy protect against PINK1 pathogenesis in Drosophila melanogaster. PLoS Genet. 2010, 6(12):e1001237.
-
(2010)
PLoS Genet.
, vol.6
, Issue.12
-
-
Liu, S.1
Lu, B.2
-
42
-
-
84859237566
-
Parkinson's disease-associated kinase PINK1 regulates miro protein level and axonal transport of mitochondria
-
Liu S., Sawada T., et al. Parkinson's disease-associated kinase PINK1 regulates miro protein level and axonal transport of mitochondria. PLoS Genet. 2012, 8(3):e1002537.
-
(2012)
PLoS Genet.
, vol.8
, Issue.3
-
-
Liu, S.1
Sawada, T.2
-
43
-
-
69249096578
-
Loss of Parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation
-
Lutz A.K., Exner N., et al. Loss of Parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation. J. Biol. Chem. 2009, 284(34):22938-22951.
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.34
, pp. 22938-22951
-
-
Lutz, A.K.1
Exner, N.2
-
44
-
-
0027995435
-
Complex I, iron, and ferritin in Parkinson's disease substantia nigra
-
Mann V.M., Cooper J.M., et al. Complex I, iron, and ferritin in Parkinson's disease substantia nigra. Ann. Neurol. 1994, 36:876-881.
-
(1994)
Ann. Neurol.
, vol.36
, pp. 876-881
-
-
Mann, V.M.1
Cooper, J.M.2
-
46
-
-
77952242572
-
The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy
-
Michiorri S., Gelmetti V., et al. The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy. Cell Death Differ. 2010, 17(6):962-974.
-
(2010)
Cell Death Differ.
, vol.17
, Issue.6
, pp. 962-974
-
-
Michiorri, S.1
Gelmetti, V.2
-
47
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate parkin
-
Narendra D.P., Jin S.M., et al. PINK1 is selectively stabilized on impaired mitochondria to activate parkin. PLoS Biol. 2010, 8(1):e1000298.
-
(2010)
PLoS Biol.
, vol.8
, Issue.1
-
-
Narendra, D.P.1
Jin, S.M.2
-
48
-
-
78649300971
-
P62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
-
Narendra D.P., Kane L.A., et al. p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both. Autophagy 2010, 6(8):1090-1106.
-
(2010)
Autophagy
, vol.6
, Issue.8
, pp. 1090-1106
-
-
Narendra, D.P.1
Kane, L.A.2
-
49
-
-
0037459081
-
Mitochondria: releasing power for life and unleashing the machineries of death
-
Newmeyer D.D., Ferguson-Miller S. Mitochondria: releasing power for life and unleashing the machineries of death. Cell 2003, 112(4):481-490.
-
(2003)
Cell
, vol.112
, Issue.4
, pp. 481-490
-
-
Newmeyer, D.D.1
Ferguson-Miller, S.2
-
50
-
-
77954104112
-
Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update
-
Nuytemans K., Theuns J., et al. Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update. Hum. Mutat. 2010, 31(7):763-780.
-
(2010)
Hum. Mutat.
, vol.31
, Issue.7
, pp. 763-780
-
-
Nuytemans, K.1
Theuns, J.2
-
51
-
-
67650246357
-
Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy
-
Okamoto K., Kondo-Okamoto N., et al. Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev. Cell 2009, 17(1):87-97.
-
(2009)
Dev. Cell
, vol.17
, Issue.1
, pp. 87-97
-
-
Okamoto, K.1
Kondo-Okamoto, N.2
-
52
-
-
77954695260
-
P62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
-
Okatsu K., Saisho K., et al. p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria. Genes Cells 2010, 15:887-900.
-
(2010)
Genes Cells
, vol.15
, pp. 887-900
-
-
Okatsu, K.1
Saisho, K.2
-
53
-
-
34548259958
-
P62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
-
Pankiv S., Clausen T.H., et al. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J. Biol. Chem. 2007, 282(33):24131-24145.
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.33
, pp. 24131-24145
-
-
Pankiv, S.1
Clausen, T.H.2
-
54
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
Park J., Lee S.B., et al. Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 2006, 441(7097):1157-1161.
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1157-1161
-
-
Park, J.1
Lee, S.B.2
-
55
-
-
84857031377
-
Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson's disease
-
Pilsl A., Winklhofer K.F. Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson's disease. Acta Neuropathol. 2012, 123(2):173-188.
-
(2012)
Acta Neuropathol.
, vol.123
, Issue.2
, pp. 173-188
-
-
Pilsl, A.1
Winklhofer, K.F.2
-
56
-
-
39449088321
-
The PINK1/Parkin pathway regulates mitochondrial morphology
-
Poole A.C., Thomas R.E., et al. The PINK1/Parkin pathway regulates mitochondrial morphology. Proc. Natl. Acad. Sci. U. S. A. 2008, 105(5):1638-1643.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, Issue.5
, pp. 1638-1643
-
-
Poole, A.C.1
Thomas, R.E.2
-
57
-
-
77955844260
-
The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/Parkin pathway
-
Poole A.C., Thomas R.E., et al. The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/Parkin pathway. PLoS One 2010, 5(4):e10054.
-
(2010)
PLoS One
, vol.5
, Issue.4
-
-
Poole, A.C.1
Thomas, R.E.2
-
58
-
-
79959242100
-
Mitochondrial contribution to Parkinson's disease pathogenesis
-
Schapira A.H., Gegg M. Mitochondrial contribution to Parkinson's disease pathogenesis. Park. Dis. 2011, 2011:159160.
-
(2011)
Park. Dis.
, vol.2011
, pp. 159160
-
-
Schapira, A.H.1
Gegg, M.2
-
59
-
-
0025254401
-
Mitochondrial complex I deficiency in Parkinson's disease
-
Schapira A.H., Cooper J.M., et al. Mitochondrial complex I deficiency in Parkinson's disease. J. Neurochem. 1990, 54:823-827.
-
(1990)
J. Neurochem.
, vol.54
, pp. 823-827
-
-
Schapira, A.H.1
Cooper, J.M.2
-
60
-
-
79959305691
-
Mitochondria: the next (neurode)generation
-
Schon E.A., Przedborski S. Mitochondria: the next (neurode)generation. Neuron 2011, 70(6):1033-1053.
-
(2011)
Neuron
, vol.70
, Issue.6
, pp. 1033-1053
-
-
Schon, E.A.1
Przedborski, S.2
-
61
-
-
37649017266
-
NIX is required for programmed mitochondrial clearance during reticulocyte maturation
-
Schweers R.L., Zhang J., et al. NIX is required for programmed mitochondrial clearance during reticulocyte maturation. Proc. Natl. Acad. Sci. U. S. A. 2007, 104(49):19500-19505.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, Issue.49
, pp. 19500-19505
-
-
Schweers, R.L.1
Zhang, J.2
-
62
-
-
77949478474
-
Phosphorylation of Parkin by Parkinson disease-linked kinase PINK1 activates Parkin E3 ligase function and NF-kappaB signaling
-
Sha D., Chin L.S., et al. Phosphorylation of Parkin by Parkinson disease-linked kinase PINK1 activates Parkin E3 ligase function and NF-kappaB signaling. Hum. Mol. Genet. 2010, 19(2):352-363.
-
(2010)
Hum. Mol. Genet.
, vol.19
, Issue.2
, pp. 352-363
-
-
Sha, D.1
Chin, L.S.2
-
63
-
-
67349239050
-
Parkin stabilizes PINK1 through direct interaction
-
Shiba K., Arai T., et al. Parkin stabilizes PINK1 through direct interaction. Biochem. Biophys. Res. Commun. 2009, 383(3):331-335.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.383
, Issue.3
, pp. 331-335
-
-
Shiba, K.1
Arai, T.2
-
64
-
-
0027021442
-
Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain
-
Soong N.W., Hinton D.R., et al. Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain. Nat. Genet. 1992, 2(4):318-323.
-
(1992)
Nat. Genet.
, vol.2
, Issue.4
, pp. 318-323
-
-
Soong, N.W.1
Hinton, D.R.2
-
65
-
-
79961239061
-
Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo
-
Sterky F.H., Lee S., et al. Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo. Proc. Natl. Acad. Sci. U. S. A. 2011, 108(31):12937-12942.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, Issue.31
, pp. 12937-12942
-
-
Sterky, F.H.1
Lee, S.2
-
66
-
-
81255149611
-
The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease
-
Surmeier D.J., Guzman J.N., et al. The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease. Neuroscience 2011, 198:221-231.
-
(2011)
Neuroscience
, vol.198
, pp. 221-231
-
-
Surmeier, D.J.1
Guzman, J.N.2
-
67
-
-
78650729600
-
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
-
Tanaka A., Cleland M.M., et al. Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin. J. Cell Biol. 2010, 191(7):1367-1380.
-
(2010)
J. Cell Biol.
, vol.191
, Issue.7
, pp. 1367-1380
-
-
Tanaka, A.1
Cleland, M.M.2
-
68
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
Twig G., Elorza A., et al. Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J. 2008, 27(2):433-446.
-
(2008)
EMBO J.
, vol.27
, Issue.2
, pp. 433-446
-
-
Twig, G.1
Elorza, A.2
-
69
-
-
49349102894
-
Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view
-
Twig G., Hyde B., et al. Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view. Biochim. Biophys. Acta 2008, 1777(9):1092-1097.
-
(2008)
Biochim. Biophys. Acta
, vol.1777
, Issue.9
, pp. 1092-1097
-
-
Twig, G.1
Hyde, B.2
-
70
-
-
62749138404
-
Molecular interaction between Parkin and PINK1 in mammalian neuronal cells
-
Um J.W., Stichel-Gunkel C., et al. Molecular interaction between Parkin and PINK1 in mammalian neuronal cells. Mol. Cell. Neurosci. 2009, 40(4):421-432.
-
(2009)
Mol. Cell. Neurosci.
, vol.40
, Issue.4
, pp. 421-432
-
-
Um, J.W.1
Stichel-Gunkel, C.2
-
71
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
Valente E.M., bou-Sleiman P.M., et al. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 2004, 304(5674):1158-1160.
-
(2004)
Science
, vol.304
, Issue.5674
, pp. 1158-1160
-
-
Valente, E.M.1
bou-Sleiman, P.M.2
-
72
-
-
79551603345
-
Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization
-
Van Laar V.S., Arnold B., et al. Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization. Hum. Mol. Genet. 2011, 20(5):927-940.
-
(2011)
Hum. Mol. Genet.
, vol.20
, Issue.5
, pp. 927-940
-
-
Van Laar, V.S.1
Arnold, B.2
-
73
-
-
75949098487
-
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
-
Vives-Bauza C., Zhou C., et al. PINK1-dependent recruitment of Parkin to mitochondria in mitophagy. Proc. Natl. Acad. Sci. U. S. A. 2010, 107(1):378-383.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, Issue.1
, pp. 378-383
-
-
Vives-Bauza, C.1
Zhou, C.2
-
74
-
-
79952319773
-
Mitochondria removal by autophagy
-
Wang K., Klionsky D.J. Mitochondria removal by autophagy. Autophagy 2011, 7(3):297-300.
-
(2011)
Autophagy
, vol.7
, Issue.3
, pp. 297-300
-
-
Wang, K.1
Klionsky, D.J.2
-
75
-
-
81055140895
-
PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility
-
Wang X., Winter D., et al. PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell 2011, 147(4):893-906.
-
(2011)
Cell
, vol.147
, Issue.4
, pp. 893-906
-
-
Wang, X.1
Winter, D.2
-
76
-
-
64549112144
-
Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking
-
Weihofen A., Thomas K.J., et al. Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking. Biochemistry 2009, 48(9):2045-2052.
-
(2009)
Biochemistry
, vol.48
, Issue.9
, pp. 2045-2052
-
-
Weihofen, A.1
Thomas, K.J.2
-
77
-
-
79960826207
-
The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons
-
Yu W., Sun Y., et al. The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons. Hum. Mol. Genet. 2011, 20(16):3227-3240.
-
(2011)
Hum. Mol. Genet.
, vol.20
, Issue.16
, pp. 3227-3240
-
-
Yu, W.1
Sun, Y.2
-
78
-
-
67549101188
-
Role of BNIP3 and NIX in cell death, autophagy, and mitophagy
-
Zhang J., Ney P.A. Role of BNIP3 and NIX in cell death, autophagy, and mitophagy. Cell Death Differ. 2009, 16(7):939-946.
-
(2009)
Cell Death Differ.
, vol.16
, Issue.7
, pp. 939-946
-
-
Zhang, J.1
Ney, P.A.2
-
79
-
-
0034194472
-
Influence of membrane physical state on the lysosomal proton permeability
-
Zhang G.J., Liu H.W., et al. Influence of membrane physical state on the lysosomal proton permeability. J. Membr. Biol. 2000, 175(1):53-62.
-
(2000)
J. Membr. Biol.
, vol.175
, Issue.1
, pp. 53-62
-
-
Zhang, G.J.1
Liu, H.W.2
-
80
-
-
59249097472
-
Mitophagy in mammalian cells: the reticulocyte model
-
Zhang J., Kundu M., et al. Mitophagy in mammalian cells: the reticulocyte model. Methods Enzymol. 2009, 452:227-245.
-
(2009)
Methods Enzymol.
, vol.452
, pp. 227-245
-
-
Zhang, J.1
Kundu, M.2
-
81
-
-
50149121528
-
The kinase domain of mitochondrial PINK1 faces the cytoplasm
-
Zhou C., Huang Y., et al. The kinase domain of mitochondrial PINK1 faces the cytoplasm. Proc. Natl. Acad. Sci. U. S. A. 2008, 105(33):12022-12027.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, Issue.33
, pp. 12022-12027
-
-
Zhou, C.1
Huang, Y.2
-
82
-
-
70349153899
-
Mitochondrial transport dynamics in axons and dendrites
-
Zinsmaier K.E., Babic M., et al. Mitochondrial transport dynamics in axons and dendrites. Results Probl. Cell Differ. 2009, 48:107-139.
-
(2009)
Results Probl. Cell Differ.
, vol.48
, pp. 107-139
-
-
Zinsmaier, K.E.1
Babic, M.2
|