메뉴 건너뛰기




Volumn 83, Issue 4, 2013, Pages 814-821

Membrane tethered bursicon constructs as heterodimeric modulators of the Drosophila G protein-coupled receptor rickets

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; DROSOPHILA G PROTEIN COUPLED RECEPTOR RICKET; G PROTEIN COUPLED RECEPTOR; LIGAND; UNCLASSIFIED DRUG;

EID: 84875469072     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.112.081570     Document Type: Article
Times cited : (11)

References (38)
  • 1
    • 33947375922 scopus 로고    scopus 로고
    • Identification of amino acid determinants of dopamine 2 receptor synthetic agonist function
    • Al-Fulaij MA, Ren Y, Beinborn M, and Kopin AS (2007) Identification of amino acid determinants of dopamine 2 receptor synthetic agonist function. J Pharmacol Exp Ther 321:298-307.
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 298-307
    • Al-Fulaij, M.A.1    Ren, Y.2    Beinborn, M.3    Kopin, A.S.4
  • 2
    • 59649090971 scopus 로고    scopus 로고
    • Identification of a novel bursiconregulated transcriptional regulator, md13379, in the house fly Musca domestica
    • An S, Wang S, Stanley D, and Song Q (2009) Identification of a novel bursiconregulated transcriptional regulator, md13379, in the house fly Musca domestica. Arch Insect Biochem Physiol 70:106-121.
    • (2009) Arch Insect Biochem Physiol , vol.70 , pp. 106-121
    • An, S.1    Wang, S.2    Stanley, D.3    Song, Q.4
  • 3
    • 77958508093 scopus 로고    scopus 로고
    • "The King is dead": Checkmating ion channels with tethered toxins
    • Auer S and Ibañez-Tallon I (2010) "The King is dead": Checkmating ion channels with tethered toxins. Toxicon 56:1293-1298.
    • (2010) Toxicon , vol.56 , pp. 1293-1298
    • Auer, S.1    Ibañez-Tallon, I.2
  • 4
    • 0347916881 scopus 로고    scopus 로고
    • Comparative genomic analysis of the eight-membered ring cystine knot-containing bone morphogenetic protein antagonists
    • Avsian-Kretchmer O and Hsueh AJ (2004) Comparative genomic analysis of the eight-membered ring cystine knot-containing bone morphogenetic protein antagonists. Mol Endocrinol 18:1-12.
    • (2004) Mol Endocrinol , vol.18 , pp. 1-12
    • Avsian-Kretchmer, O.1    Hsueh, A.J.2
  • 5
    • 77955052378 scopus 로고    scopus 로고
    • Functional characterization of bursicon receptor and genome-wide analysis for identification of genes affected by bursicon receptor RNAi
    • Bai H and Palli SR (2010) Functional characterization of bursicon receptor and genome-wide analysis for identification of genes affected by bursicon receptor RNAi. Dev Biol 344:248-258.
    • (2010) Dev Biol , vol.344 , pp. 248-258
    • Bai, H.1    Palli, S.R.2
  • 6
    • 0036121842 scopus 로고    scopus 로고
    • Truncated equine LH beta and asparagine(56)-deglycosylated equine LH alpha combine to produce a potent FSH antagonist
    • Butnev VY, Singh V, Nguyen VT, and Bousfield GR (2002) Truncated equine LH beta and asparagine(56)-deglycosylated equine LH alpha combine to produce a potent FSH antagonist. J Endocrinol 172:545-555.
    • (2002) J Endocrinol , vol.172 , pp. 545-555
    • Butnev, V.Y.1    Singh, V.2    Nguyen, V.T.3    Bousfield, G.R.4
  • 7
    • 67650976340 scopus 로고    scopus 로고
    • Cellular dissection of circadian peptide signals with genetically encoded membranetethered ligands
    • Choi C, Fortin JP, McCarthy Ev, Oksman L, Kopin AS, and Nitabach MN (2009) Cellular dissection of circadian peptide signals with genetically encoded membranetethered ligands. Curr Biol 19:1167-1175.
    • (2009) Curr Biol , vol.19 , pp. 1167-1175
    • Choi, C.1    Fortin, J.P.2    McCarthy, Ev.3    Oksman, L.4    Kopin, A.S.5    Nitabach, M.N.6
  • 8
    • 0034686019 scopus 로고    scopus 로고
    • Cystine knot mutations affect the folding of the glycoprotein hormone alpha-subunit. Differential secretion and assembly of partially folded intermediates
    • Darling RJ, Ruddon RW, Perini F, and Bedows E (2000) Cystine knot mutations affect the folding of the glycoprotein hormone alpha-subunit. Differential secretion and assembly of partially folded intermediates. J Biol Chem 275:15413-15421.
    • (2000) J Biol Chem , vol.275 , pp. 15413-15421
    • Darling, R.J.1    Ruddon, R.W.2    Perini, F.3    Bedows, E.4
  • 10
    • 84864131402 scopus 로고    scopus 로고
    • Selected melanocortin 1 receptor single-nucleotide polymorphisms differentially alter multiple signaling pathways
    • Doyle JR, Fortin JP, Beinborn M, and Kopin AS (2012) Selected melanocortin 1 receptor single-nucleotide polymorphisms differentially alter multiple signaling pathways. J Pharmacol Exp Ther 342:318-326.
    • (2012) J Pharmacol Exp Ther , vol.342 , pp. 318-326
    • Doyle, J.R.1    Fortin, J.P.2    Beinborn, M.3    Kopin, A.S.4
  • 12
    • 0033855185 scopus 로고    scopus 로고
    • Molecular cloning, genomic organization, developmental regulation, and a knock-out mutant of a novel leu-rich repeats-containing G protein-coupled receptor (DLGR-2) from Drosophila melanogaster
    • Eriksen KK, Hauser F, Schiøtt M, Pedersen KM, Søndergaard L, and Grimmelikhuijzen CJ (2000) Molecular cloning, genomic organization, developmental regulation, and a knock-out mutant of a novel leu-rich repeats-containing G protein-coupled receptor (DLGR-2) from Drosophila melanogaster. Genome Res 10:924-938.
    • (2000) Genome Res , vol.10 , pp. 924-938
    • Eriksen, K.K.1    Hauser, F.2    Schiøtt, M.3    Pedersen, K.M.4    Søndergaard, L.5    Grimmelikhuijzen, C.J.6
  • 14
    • 80052868932 scopus 로고    scopus 로고
    • Discovery of dualaction membrane-anchored modulators of incretin receptors
    • Fortin JP, Chinnapen D, BeinbornM, LencerW, and Kopin AS (2011) Discovery of dualaction membrane-anchored modulators of incretin receptors. PLoS ONE 6:e24693.
    • (2011) PLoS ONE , vol.6
    • Fortin, J.P.1    Chinnapen, D.2    Beinborn, M.3    Lencer, W.4    Kopin, A.S.5
  • 15
    • 66049138465 scopus 로고    scopus 로고
    • Membrane-tethered ligands are effective probes for exploring class B1 G proteincoupled receptor function
    • Fortin JP, Zhu Y, Choi C, Beinborn M, Nitabach MN, and Kopin AS (2009) Membrane-tethered ligands are effective probes for exploring class B1 G proteincoupled receptor function. Proc Natl Acad Sci USA 106:8049-8054.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 8049-8054
    • Fortin, J.P.1    Zhu, Y.2    Choi, C.3    Beinborn, M.4    Nitabach, M.N.5    Kopin, A.S.6
  • 16
    • 70349768778 scopus 로고    scopus 로고
    • The beta104-109 sequence is essential for the secretion of correctly folded single-chain beta alpha horse LH/CG and for its FSH activity
    • Galet C, Guillou F, Foulon-Gauze F, Combarnous Y, and Chopineau M (2009) The beta104-109 sequence is essential for the secretion of correctly folded single-chain beta alpha horse LH/CG and for its FSH activity. J Endocrinol 203:167-174.
    • (2009) J Endocrinol , vol.203 , pp. 167-174
    • Galet, C.1    Guillou, F.2    Foulon-Gauze, F.3    Combarnous, Y.4    Chopineau, M.5
  • 17
    • 0037195185 scopus 로고    scopus 로고
    • A Drosophila dopamine 2-like receptor: Molecular characterization and identification of multiple alternatively spliced variants
    • Hearn MG, Ren Y, McBride EW, Reveillaud I, Beinborn M, and Kopin AS (2002) A Drosophila dopamine 2-like receptor: Molecular characterization and identification of multiple alternatively spliced variants. Proc Natl Acad Sci USA 99: 14554-14559.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 14554-14559
    • Hearn, M.G.1    Ren, Y.2    McBride, E.W.3    Reveillaud, I.4    Beinborn, M.5    Kopin, A.S.6
  • 18
    • 0033829535 scopus 로고    scopus 로고
    • Molecular architecture and biorecognition processes of the cystine knot protein superfamily: Part I. The glycoprotein hormones
    • Hearn MT and Gomme PT (2000) Molecular architecture and biorecognition processes of the cystine knot protein superfamily: part I. The glycoprotein hormones. J Mol Recognit 13:223-278.
    • (2000) J Mol Recognit , vol.13 , pp. 223-278
    • Hearn, M.T.1    Gomme, P.T.2
  • 19
    • 16244383540 scopus 로고    scopus 로고
    • Mechanisms of peptide and nonpeptide ligand binding to Class B Gprotein- coupled receptors
    • Hoare SR (2005) Mechanisms of peptide and nonpeptide ligand binding to Class B Gprotein- coupled receptors. Drug Discov Today 10:417-427.
    • (2005) Drug Discov Today , vol.10 , pp. 417-427
    • Hoare, S.R.1
  • 20
    • 56649107996 scopus 로고    scopus 로고
    • Bursicon, the tanning hormone of insects: Recent advances following the discovery of its molecular identity
    • Honegger HW, Dewey EM, and Ewer J (2008) Bursicon, the tanning hormone of insects: recent advances following the discovery of its molecular identity. J Comp Physiol A Neuroethol Sens Neural Behav Physiol 194:989-1005.
    • (2008) J Comp Physiol A Neuroethol Sens Neural Behav Physiol , vol.194 , pp. 989-1005
    • Honegger, H.W.1    Dewey, E.M.2    Ewer, J.3
  • 21
    • 79959877090 scopus 로고    scopus 로고
    • Bursicon-expressing neurons undergo apoptosis after adult ecdysis in the mosquito Anopheles gambiae
    • Honegger HW, Estévez-Lao TY, and Hillyer JF (2011) Bursicon-expressing neurons undergo apoptosis after adult ecdysis in the mosquito Anopheles gambiae. J Insect Physiol 57:1017-1022.
    • (2011) J Insect Physiol , vol.57 , pp. 1017-1022
    • Honegger, H.W.1    Estévez-Lao, T.Y.2    Hillyer, J.F.3
  • 22
    • 84857686980 scopus 로고    scopus 로고
    • Tethering toxins and peptide ligands for modulation of neuronal function
    • Ibañez-Tallon I and Nitabach MN (2012) Tethering toxins and peptide ligands for modulation of neuronal function. Curr Opin Neurobiol 22:72-78.
    • (2012) Curr Opin Neurobiol , vol.22 , pp. 72-78
    • Ibañez-Tallon, I.1    Nitabach, M.N.2
  • 23
    • 77956474155 scopus 로고    scopus 로고
    • The essential role of bursicon during Drosophila development
    • Loveall BJ and Deitcher DL (2010) The essential role of bursicon during Drosophila development. BMC Dev Biol 10:92.
    • (2010) BMC Dev Biol , vol.10 , pp. 92
    • Loveall, B.J.1    Deitcher, D.L.2
  • 25
    • 14544303674 scopus 로고    scopus 로고
    • Bursicon, the insect cuticle-hardening hormone, is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2
    • Luo CW, Dewey EM, Sudo S, Ewer J, Hsu SY, Honegger HW, and Hsueh AJ (2005) Bursicon, the insect cuticle-hardening hormone, is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2. Proc Natl Acad Sci USA 102:2820-2825.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 2820-2825
    • Luo, C.W.1    Dewey, E.M.2    Sudo, S.3    Ewer, J.4    Hsu, S.Y.5    Honegger, H.W.6    Hsueh, A.J.7
  • 27
    • 0035958068 scopus 로고    scopus 로고
    • Identification of receptor binding and activation determinants in the N-terminal and N-loop regions of the CC chemokine eotaxin
    • Mayer MR and Stone MJ (2001) Identification of receptor binding and activation determinants in the N-terminal and N-loop regions of the CC chemokine eotaxin. J Biol Chem 276:13911-13916.
    • (2001) J Biol Chem , vol.276 , pp. 13911-13916
    • Mayer, M.R.1    Stone, M.J.2
  • 29
    • 24644517497 scopus 로고    scopus 로고
    • Conservation of the heterodimeric glycoprotein hormone subunit family proteins and the LGR signaling system from nematodes to humans
    • Park JI, Semyonov J, Chang CL, and Hsu SY (2005) Conservation of the heterodimeric glycoprotein hormone subunit family proteins and the LGR signaling system from nematodes to humans. Endocrine 26:267-276.
    • (2005) Endocrine , vol.26 , pp. 267-276
    • Park, J.I.1    Semyonov, J.2    Chang, C.L.3    Hsu, S.Y.4
  • 30
    • 56649088501 scopus 로고    scopus 로고
    • Bursicon functions within the Drosophila CNS to modulate wing expansion behavior, hormone secretion, and cell death
    • Peabody NC, Diao F, Luan H, Wang H, Dewey EM, Honegger HW, and White BH (2008) Bursicon functions within the Drosophila CNS to modulate wing expansion behavior, hormone secretion, and cell death. J Neurosci 28:14379-14391.
    • (2008) J Neurosci , vol.28 , pp. 14379-14391
    • Peabody, N.C.1    Diao, F.2    Luan, H.3    Wang, H.4    Dewey, E.M.5    Honegger, H.W.6    White, B.H.7
  • 31
    • 0030739370 scopus 로고    scopus 로고
    • Cystine knot of the gonadotropin alpha subunit is critical for intracellular behavior but not for in vitro biological activity
    • Sato A, Perlas E, Ben-Menahem D, Kudo M, Pixley MR, Furuhashi M, Hsueh AJ, and Boime I (1997) Cystine knot of the gonadotropin alpha subunit is critical for intracellular behavior but not for in vitro biological activity. J Biol Chem 272: 18098-18103.
    • (1997) J Biol Chem , vol.272 , pp. 18098-18103
    • Sato, A.1    Perlas, E.2    Ben-Menahem, D.3    Kudo, M.4    Pixley, M.R.5    Furuhashi, M.6    Hsueh, A.J.7    Boime, I.8
  • 32
    • 0034078160 scopus 로고    scopus 로고
    • Biological activity of single chain chorionic gonadotropin, hCGalphabeta, is decreased upon deletion of five carboxyl terminal amino acids of the alpha subunit without affecting its receptor binding
    • Sen Gupta C and Dighe RR (2000) Biological activity of single chain chorionic gonadotropin, hCGalphabeta, is decreased upon deletion of five carboxyl terminal amino acids of the alpha subunit without affecting its receptor binding. J Mol Endocrinol 24:157-164.
    • (2000) J Mol Endocrinol , vol.24 , pp. 157-164
    • Sen Gupta, C.1    Dighe, R.R.2
  • 33
    • 33845597768 scopus 로고    scopus 로고
    • Single chain human chorionic gonadotropin, hCGalphabeta: Effects of mutations in the alpha subunit on structure and bioactivity
    • Setlur SR and Dighe RR (2007) Single chain human chorionic gonadotropin, hCGalphabeta: effects of mutations in the alpha subunit on structure and bioactivity. Glycoconj J 24:97-106.
    • (2007) Glycoconj J , vol.24 , pp. 97-106
    • Setlur, S.R.1    Dighe, R.R.2
  • 34
    • 0030596069 scopus 로고    scopus 로고
    • Expression of biologically active fusion genes encoding the common alpha subunit and either the CG beta or FSH beta subunits: Role of a linker sequence
    • Sugahara T, Grootenhuis PD, Sato A, Kudo M, Ben-Menahem D, Pixley MR, Hsueh AJ, and Boime I (1996) Expression of biologically active fusion genes encoding the common alpha subunit and either the CG beta or FSH beta subunits: role of a linker sequence. Mol Cell Endocrinol 125:71-77.
    • (1996) Mol Cell Endocrinol , vol.125 , pp. 71-77
    • Sugahara, T.1    Grootenhuis, P.D.2    Sato, A.3    Kudo, M.4    Ben-Menahem, D.5    Pixley, M.R.6    Hsueh, A.J.7    Boime, I.8
  • 37
    • 4143117844 scopus 로고    scopus 로고
    • Glycoprotein hormone assembly in the endoplasmic reticulum: IV. Probable mechanism of subunit docking and completion of assembly
    • Xing Y, Myers RV, Cao D, Lin W, Jiang M, Bernard MP, and Moyle WR (2004) Glycoprotein hormone assembly in the endoplasmic reticulum: IV. Probable mechanism of subunit docking and completion of assembly. J Biol Chem 279:35458-35468.
    • (2004) J Biol Chem , vol.279 , pp. 35458-35468
    • Xing, Y.1    Myers, R.V.2    Cao, D.3    Lin, W.4    Jiang, M.5    Bernard, M.P.6    Moyle, W.R.7
  • 38
    • 4644286010 scopus 로고    scopus 로고
    • Effective polyethylenimine-mediated gene transfer into human endothelial cells
    • Zaric V, Weltin D, Erbacher P, Remy JS, Behr JP, and Stephan D (2004) Effective polyethylenimine-mediated gene transfer into human endothelial cells. J Gene Med 6:176-184.
    • (2004) J Gene Med , vol.6 , pp. 176-184
    • Zaric, V.1    Weltin, D.2    Erbacher, P.3    Remy, J.S.4    Behr, J.P.5    Stephan, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.