-
1
-
-
0032539644
-
The human follitropin alpha-subunit C-terminus collaborates with a β subunit cystine noose and an alpha-subunit loop to assemble a receptor binding domain competent for signal transduction
-
Arnold CJ, Liu C, Lindau-Shepard B, Losavio ML, Patrascu MT & Dias J 1998 The human follitropin alpha-subunit C-terminus collaborates with a β subunit cystine noose and an alpha-subunit loop to assemble a receptor binding domain competent for signal transduction. Biochemistry 37 1762-1768.
-
(1998)
Biochemistry
, vol.37
, pp. 1762-1768
-
-
Arnold, C.J.1
Liu, C.2
Lindau-Shepard, B.3
Losavio, M.L.4
Patrascu, M.T.5
Dias, J.6
-
2
-
-
0019364734
-
Characterization of several clonal lines of cultured Leydig tumour cells: Gonadotropin receptors and steroidogenic responses
-
Ascoli, M 1981 Characterization of several clonal lines of cultured Leydig tumour cells: gonadotropin receptors and steroidogenic responses. Endocrinology 108 88-95.
-
(1981)
Endocrinology
, vol.108
, pp. 88-95
-
-
Ascoli, M.1
-
3
-
-
0030959878
-
The biologic action of single-chain choriogonaotropin is not dependent on the individual disulfide bonds of the beta subunit
-
Ben-Mannhein D, Kudo M, Pixley MR, Sato A, Suganuma N, Perlas E, Hsueh AJW & Boime I 1997 The biologic action of single-chain choriogonaotropin is not dependent on the individual disulfide bonds of the beta subunit. Journal of Biological Chemistry 272 6827-6830.
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 6827-6830
-
-
Ben-Mannhein, D.1
Kudo, M.2
Pixley, M.R.3
Sato, A.4
Suganuma, N.5
Perlas, E.6
Hsueh, A.J.W.7
Boime, I.8
-
5
-
-
0342390002
-
-
th Annual Meeting of Society for the Study of Reproduction 274, abstract no. 584. Biology of Reproduction 60 (Suppl 1) 1999.
-
Biology of Reproduction
, vol.60
, Issue.SUPPL. 1
, pp. 1999
-
-
-
6
-
-
0242520134
-
Site directed mutagenesis identifies two receptor binding domains in the human chorionic gonadotropin α subunit
-
Bielinski M, Pixley MR & Boime I 1990 Site directed mutagenesis identifies two receptor binding domains in the human chorionic gonadotropin α subunit. Journal of Cell Biology 111 330a.
-
(1990)
Journal of Cell Biology
, vol.111
-
-
Bielinski, M.1
Pixley, M.R.2
Boime, I.3
-
7
-
-
0026635335
-
The carboxyl terminal region of the glycoprotein hormone alpha-subunit: Contributions to receptor binding and signaling in human chorionic gonadotropin
-
Chen F, Wang Y & Puett D 1992 The carboxyl terminal region of the glycoprotein hormone alpha-subunit: contributions to receptor binding and signaling in human chorionic gonadotropin. Molecular Endocrinology 6 914-919.
-
(1992)
Molecular Endocrinology
, vol.6
, pp. 914-919
-
-
Chen, F.1
Wang, Y.2
Puett, D.3
-
8
-
-
0020590536
-
Use of α- and β- subunit specific antibodies in studying interaction of hCG with Leydig cell receptors Arch
-
Dighe RR & Moudgal NR 1983 Use of α-and β-subunit specific antibodies in studying interaction of hCG with Leydig cell receptors Arch. Biochemical and Biophysical Research 225 490-499.
-
(1983)
Biochemical and Biophysical Research
, vol.225
, pp. 490-499
-
-
Dighe, R.R.1
Moudgal, N.R.2
-
9
-
-
0025340220
-
Two simple and rapid methods to detect monoclonal antibodies with identical epitope specificities in a large population of monoclonal antibodies
-
Dighe RR, Murthy GS & Moudgal NR 1990a Two simple and rapid methods to detect monoclonal antibodies with identical epitope specificities in a large population of monoclonal antibodies. Journal of Immunological Methods 131 229-236.
-
(1990)
Journal of Immunological Methods
, vol.131
, pp. 229-236
-
-
Dighe, R.R.1
Murthy, G.S.2
Moudgal, N.R.3
-
10
-
-
0025345989
-
Conformation of the α-subunit of glycoprotein hormones: A study using polyclonal and monoclonal antibodies
-
Dighe RR, Murthy GS, Kurkalli BS & Moudgal NR 1990b Conformation of the α-subunit of glycoprotein hormones: a study using polyclonal and monoclonal antibodies. Molecular Cell Endocrinology 72 63-70.
-
(1990)
Molecular Cell Endocrinology
, vol.72
, pp. 63-70
-
-
Dighe, R.R.1
Murthy, G.S.2
Kurkalli, B.S.3
Moudgal, N.R.4
-
11
-
-
0028831206
-
Fusing the carboxy-terminal peptide of the chorionic gonadotropin (CG) beta-subunit to the common α subunit: Retention of O-linked glycosylation and enhanced in vivo bioactivity of chimeric human CG
-
Furuhashi M, Shikone T, Fares F, Sugahara T, Hsueh AJW & Boime I 1995 Fusing the carboxy-terminal peptide of the chorionic gonadotropin (CG) beta-subunit to the common α subunit: retention of O-linked glycosylation and enhanced in vivo bioactivity of chimeric human CG. Molecular Endocrinology 9 54-63.
-
(1995)
Molecular Endocrinology
, vol.9
, pp. 54-63
-
-
Furuhashi, M.1
Shikone, T.2
Fares, F.3
Sugahara, T.4
Hsueh, A.J.W.5
Boime, I.6
-
12
-
-
0030816072
-
Design of stable biologically active recombinant lutropin analogs
-
Gracia-Campayo V, Sato A, Hirsch B, Sugahara T, Muyan M, Hsueh AJW & Boime I 1997 Design of stable biologically active recombinant lutropin analogs. Nature Biotechnology 15 663-667.
-
(1997)
Nature Biotechnology
, vol.15
, pp. 663-667
-
-
Gracia-Campayo, V.1
Sato, A.2
Hirsch, B.3
Sugahara, T.4
Muyan, M.5
Hsueh, A.J.W.6
Boime, I.7
-
13
-
-
0029135420
-
Role of carboxy-terminal residues of the α subunit in the expression and bioactivity of human thyroid stimulating hormone
-
Grossmann M, Szkudlinski MW, Zeng H, Kraiem Z, Ji I, Tropea JE, Ji TH & Weintraub BD 1995 Role of carboxy-terminal residues of the α subunit in the expression and bioactivity of human thyroid stimulating hormone Molecular Endocrinology 9 948-958.
-
(1995)
Molecular Endocrinology
, vol.9
, pp. 948-958
-
-
Grossmann, M.1
Szkudlinski, M.W.2
Zeng, H.3
Kraiem, Z.4
Ji, I.5
Tropea, J.E.6
Ji, T.H.7
Weintraub, B.D.8
-
14
-
-
0030881847
-
Human thyroid stimulating hormone (hTSH) subunit gene fusion produces hTSH with increased stability and serum half-life and compensates for mutagenesis-induced defects in subunit association
-
Grossmann M, Wong R, Szkudlinski MW & Weintraub BD 1997a Human thyroid stimulating hormone (hTSH) subunit gene fusion produces hTSH with increased stability and serum half-life and compensates for mutagenesis-induced defects in subunit association. Journal of Biological Chemistry 272 21312-21316.
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 21312-21316
-
-
Grossmann, M.1
Wong, R.2
Szkudlinski, M.W.3
Weintraub, B.D.4
-
15
-
-
0030852648
-
Novel insights into the molecular mechanisms of human thyrotropin action: Structural, physiological and therapeutic implications for the glycoprotein hormone family
-
Grossmann M, Weintraub BD & Szkudlinski MW 1997b Novel insights into the molecular mechanisms of human thyrotropin action: structural, physiological and therapeutic implications for the glycoprotein hormone family. Endocrine Review 18 476-501.
-
(1997)
Endocrine Review
, vol.18
, pp. 476-501
-
-
Grossmann, M.1
Weintraub, B.D.2
Szkudlinski, M.W.3
-
16
-
-
0027371827
-
Receptor activation of and signal generation by the lutropin/choriogonadotropin receptor. Cooperation of Asp397 of the receptor and alpha Lys91 of the hormone
-
Ji I, Zeng H & Ji TH 1993 Receptor activation of and signal generation by the lutropin/choriogonadotropin receptor. Cooperation of Asp397 of the receptor and alpha Lys91 of the hormone. Journal of Biological Chemistry 268 22971-22974.
-
(1993)
Journal of Biological Chemistry
, vol.268
, pp. 22971-22974
-
-
Ji, I.1
Zeng, H.2
Ji, T.H.3
-
17
-
-
0028239813
-
Crystal structure of human chorionic gonadotropin
-
Lapthorn AJ, Harris DC, Littlejohn A, Lustbader JW, Canfield RE, Machin KJ, Morgan FJ & Isaacs NW 1994 Crystal structure of human chorionic gonadotropin. Nature 369 455-461.
-
(1994)
Nature
, vol.369
, pp. 455-461
-
-
Lapthorn, A.J.1
Harris, D.C.2
Littlejohn, A.3
Lustbader, J.W.4
Canfield, R.E.5
Machin, K.J.6
Morgan, F.J.7
Isaacs, N.W.8
-
18
-
-
0018639424
-
Studies of the specific role of the subunits of choriogonadotropin for biological, immunological and physical properties of the hormone. Digestion of the alpha-subunit with carboxypeptidase A
-
Merz WE 1979 Studies of the specific role of the subunits of choriogonadotropin for biological, immunological and physical properties of the hormone. Digestion of the alpha-subunit with carboxypeptidase A. European Journal of Biochemistry 101 541-553.
-
(1979)
European Journal of Biochemistry
, vol.101
, pp. 541-553
-
-
Merz, W.E.1
-
19
-
-
51249171657
-
Relative ability of ovine follicle stimulating hormone and its β subunit to generate antibodies having bioneutralization potential in nonhuman primates
-
Moudgal NR, Siaram NR & Dighe RR 1989 Relative ability of ovine follicle stimulating hormone and its β subunit to generate antibodies having bioneutralization potential in nonhuman primates. Journal of Biosciences 14 91-100.
-
(1989)
Journal of Biosciences
, vol.14
, pp. 91-100
-
-
Moudgal, N.R.1
Siaram, N.R.2
Dighe, R.R.3
-
20
-
-
0028882196
-
Functional expression of yoked human chorionic gonadotropin baculovirus-infected insect cells
-
Narayan P, Wu C & Puett D 1995 Functional expression of yoked human chorionic gonadotropin baculovirus-infected insect cells. Molecular Endocrinology 9 1720-1726.
-
(1995)
Molecular Endocrinology
, vol.9
, pp. 1720-1726
-
-
Narayan, P.1
Wu, C.2
Puett, D.3
-
23
-
-
0031864755
-
The tie that binds: Design of biologically active single-chain human chorionic gonadotropins and a gonadotropin-receptor complex using protein engineering
-
Puett D, Wu C & Narayan P 1998 The tie that binds: design of biologically active single-chain human chorionic gonadotropins and a gonadotropin-receptor complex using protein engineering. Biology of Reproduction 58 1337-1342.
-
(1998)
Biology of Reproduction
, vol.58
, pp. 1337-1342
-
-
Puett, D.1
Wu, C.2
Narayan, P.3
-
24
-
-
0031214645
-
Expression of biologically active β subunit of bovine follicle stimulating hormone in the methylotropic yeast Pichia pastoris
-
Samaddar M, Catterall JF & Dighe RR 1997 Expression of biologically active β subunit of bovine follicle stimulating hormone in the methylotropic yeast Pichia pastoris. Protein Expression & Purification 10 345-355.
-
(1997)
Protein Expression & Purification
, vol.10
, pp. 345-355
-
-
Samaddar, M.1
Catterall, J.F.2
Dighe, R.R.3
-
25
-
-
0344603650
-
Hyperexpression of biologically active human chorionic gonadotropin using the methylotropic yeast, Pichia pastoris
-
Sen Gupta C & Dighe RR 1999 Hyperexpression of biologically active human chorionic gonadotropin using the methylotropic yeast, Pichia pastoris. Journal of Molecular Endocrinology 22 273-283.
-
(1999)
Journal of Molecular Endocrinology
, vol.22
, pp. 273-283
-
-
Sen Gupta, C.1
Dighe, R.R.2
-
26
-
-
0030272554
-
The expression of recombinant proteins in yeasts
-
Sudbery P 1996 The expression of recombinant proteins in yeasts. Current Opinions in Biotechnology 7 517-524.
-
(1996)
Current Opinions in Biotechnology
, vol.7
, pp. 517-524
-
-
Sudbery, P.1
-
27
-
-
0028948846
-
Biosynthesis of a biologically active single peptide chain containing the human common alpha and chorionic gonadotropin beta subunits in tandem
-
Sugahara T, Pixley MR, Minami S, Perlas E, Ben-Mannhein D, Hsueh AJW & Boime I 1995 Biosynthesis of a biologically active single peptide chain containing the human common alpha and chorionic gonadotropin beta subunits in tandem. Proceedings of the National Academy of Sciences of the USA 92 2041-2045.
-
(1995)
Proceedings of the National Academy of Sciences of the USA
, vol.92
, pp. 2041-2045
-
-
Sugahara, T.1
Pixley, M.R.2
Minami, S.3
Perlas, E.4
Ben-Mannhein, D.5
Hsueh, A.J.W.6
Boime, I.7
-
28
-
-
15844427850
-
Expression of biologically active fusion genes encoding the common alpha subunit and the follicle stimulating hormone beta subunit. Role of a linker sequence
-
Sugahara T, Sato A, Kudo M, Ben-Mannhein D, Pixley MR, Hsueh AJW & Boime I 1996a Expression of biologically active fusion genes encoding the common alpha subunit and the follicle stimulating hormone beta subunit. Role of a linker sequence. Journal of Biological Chemistry 271 10445-10448.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 10445-10448
-
-
Sugahara, T.1
Sato, A.2
Kudo, M.3
Ben-Mannhein, D.4
Pixley, M.R.5
Hsueh, A.J.W.6
Boime, I.7
-
29
-
-
0030596069
-
Expression of biologically active fusion genes encoding the common alpha subunit and either the CG beta or FSH beta subunits: Role of a linker sequence
-
Sugahara T, Grootenhuis PDJ, Sato A, Kudo M, Ben-Mannhein D, Pixley MR, Hseuh AJW & Boime I 1996b Expression of biologically active fusion genes encoding the common alpha subunit and either the CG beta or FSH beta subunits: role of a linker sequence. Molecular Cell Endocrinology 125 71-77.
-
(1996)
Molecular Cell Endocrinology
, vol.125
, pp. 71-77
-
-
Sugahara, T.1
Grootenhuis, P.D.J.2
Sato, A.3
Kudo, M.4
Ben-Mannhein, D.5
Pixley, M.R.6
Hseuh, A.J.W.7
Boime, I.8
-
30
-
-
0027493757
-
COOH-terminal amino acids of the alpha subunit play common and different roles in human chorionic gonadotropin and follitropin
-
Yoo J, Zeng H, Ji I, Mudroch WJ & Ji TH 1993 COOH-terminal amino acids of the alpha subunit play common and different roles in human chorionic gonadotropin and follitropin. Journal of Biological Chemistry 268 13034-13042.
-
(1993)
Journal of Biological Chemistry
, vol.268
, pp. 13034-13042
-
-
Yoo, J.1
Zeng, H.2
Ji, I.3
Mudroch, W.J.4
Ji, T.H.5
|