메뉴 건너뛰기




Volumn 288, Issue 12, 2013, Pages 8028-8042

Role of fat body lipogenesis in protection against the effects of caloric overload in drosophila

Author keywords

[No Author keywords available]

Indexed keywords

CARBON-CHAIN LENGTH; DEGREE OF UNSATURATIONS; ELEMENT-BINDING PROTEINS; INSULIN RESISTANCE; STABLE ISOTOPE TRACERS; SUGAR FEEDING; TISSUE SPECIFICS; WORK SUPPORT;

EID: 84875441811     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.371047     Document Type: Article
Times cited : (101)

References (73)
  • 1
    • 33750719099 scopus 로고    scopus 로고
    • Effects of Macronutrient Excess and composition on oxidative stress: Relevance to diabetes and cardiovascular disease
    • DOI 10.1007/s11883-006-0022-z
    • Ceriello, A. (2006) Effects of macronutrient excess and composition on oxidative stress: relevance to diabetes and cardiovascular disease. Curr. Atheroscler. Rep. 8, 472-476 (Pubitemid 44697800)
    • (2006) Current Atherosclerosis Reports , vol.8 , Issue.6 , pp. 472-476
    • Ceriello, A.1
  • 2
    • 2942585486 scopus 로고    scopus 로고
    • Role of fatty acid composition in the development of metabolic disorders in sucrose-induced obese rats
    • Fukuchi, S., Hamaguchi, K., Seike, M., Himeno, K., Sakata, T., and Yoshimatsu, H. (2004) Role of fatty acid composition in the development of metabolic disorders in sucrose-induced obese rats. Exp. Biol. Med. 229, 486-493 (Pubitemid 38736317)
    • (2004) Experimental Biology and Medicine , vol.229 , Issue.6 , pp. 486-493
    • Fukuchi, S.1    Hamaguchi, K.2    Seike, M.3    Himeno, K.4    Sakata, T.5    Yoshimatsu, H.6
  • 3
    • 34248646013 scopus 로고    scopus 로고
    • Management of obesity in patients with type 2 diabetes mellitus
    • DOI 10.2174/157339907780598207
    • Gagliardi, L., and Wittert, G. (2007) Management of obesity in patients with type 2 diabetes mellitus. Curr. Diabetes Rev. 3, 95-101 (Pubitemid 46773849)
    • (2007) Current Diabetes Reviews , vol.3 , Issue.2 , pp. 95-101
    • Gagliardi, L.1    Wittert, G.2
  • 6
    • 47049101814 scopus 로고    scopus 로고
    • Dietary composition specifies consumption, obesity, and lifespan in Drosophila melanogaster
    • DOI 10.1111/j.1474-9726.2008.00400.x
    • Skorupa, D. A., Dervisefendic, A., Zwiener, J., and Pletcher, S. D. (2008) Dietary composition specifies consumption, obesity, and lifespan in Drosophila melanogaster. Aging Cell 7, 478-490 (Pubitemid 351998608)
    • (2008) Aging Cell , vol.7 , Issue.4 , pp. 478-490
    • Skorupa, D.A.1    Dervisefendic, A.2    Zwiener, J.3    Pletcher, S.D.4
  • 7
    • 77149177995 scopus 로고    scopus 로고
    • Implications of diet on nonalcoholic fatty liver disease
    • Sullivan, S. (2010) Implications of diet on nonalcoholic fatty liver disease. Curr. Opin. Gastroenterol. 26, 160-164
    • (2010) Curr. Opin. Gastroenterol. , vol.26 , pp. 160-164
    • Sullivan, S.1
  • 8
    • 84860448541 scopus 로고    scopus 로고
    • High sugar-induced insulin resistance in Drosophila relies on the lipocalin Neural Lazarillo
    • Pasco, M. Y., and Léopold, P. (2012) High sugar-induced insulin resistance in Drosophila relies on the lipocalin Neural Lazarillo. PLoS One 7, e36583
    • (2012) PLoS One , vol.7
    • Pasco, M.Y.1    Léopold, P.2
  • 10
    • 69149110896 scopus 로고    scopus 로고
    • Remote control of insulin secretion by fat cells in Drosophila
    • Géminard, C., Rulifson, E. J., and Léopold, P. (2009) Remote control of insulin secretion by fat cells in Drosophila. Cell Metab. 10, 199-207
    • (2009) Cell Metab. , vol.10 , pp. 199-207
    • Géminard, C.1    Rulifson, E.J.2    Léopold, P.3
  • 11
    • 79960443808 scopus 로고    scopus 로고
    • The contribution of the Drosophila model to lipid droplet research
    • Kühnlein, R. P. (2011) The contribution of the Drosophila model to lipid droplet research. Prog. Lipid Res. 50, 348-356
    • (2011) Prog. Lipid Res. , vol.50 , pp. 348-356
    • Kühnlein, R.P.1
  • 12
    • 34047268684 scopus 로고    scopus 로고
    • The host defense of Drosophila melanogaster
    • DOI 10.1146/annurev.immunol.25.022106.141615
    • Lemaitre, B., and Hoffmann, J. (2007) The host defense of Drosophila melanogaster. Annu. Rev. Immunol. 25, 697-743 (Pubitemid 46697922)
    • (2007) Annual Review of Immunology , vol.25 , pp. 697-743
    • Lemaitre, B.1    Hoffmann, J.2
  • 13
    • 71949119173 scopus 로고    scopus 로고
    • Regulation of fat cell mass by insulin in Drosophila melanogaster
    • DiAngelo, J. R., and Birnbaum, M. J. (2009) Regulation of fat cell mass by insulin in Drosophila melanogaster. Mol. Cell. Biol. 29, 6341-6352
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 6341-6352
    • Diangelo, J.R.1    Birnbaum, M.J.2
  • 14
    • 2942590660 scopus 로고    scopus 로고
    • Hemolymph sugar homeostasis and starvation-induced hyperactivity affected by genetic manipulations of the adipokinetic hormone-encoding gene in Drosophila melanogaster
    • DOI 10.1534/genetics.167.1.311
    • Lee, G., and Park, J. H. (2004) Hemolymph sugar homeostasis and starvation- induced hyperactivity affected by genetic manipulations of the adipokinetic hormone-encoding gene in Drosophila melanogaster. Genetics 167, 311-323 (Pubitemid 38736390)
    • (2004) Genetics , vol.167 , Issue.1 , pp. 311-323
    • Lee, G.1    Park, J.H.2
  • 16
    • 58149159849 scopus 로고    scopus 로고
    • Systematic review of randomized controlled trials of low-carbohydrate vs. low-fat/low-calorie diets in the management of obesity and its comorbidities
    • Hession, M., Rolland, C., Kulkarni, U., Wise, A., and Broom, J. (2009) Systematic review of randomized controlled trials of low-carbohydrate vs. low-fat/low-calorie diets in the management of obesity and its comorbidities. Obes. Rev. 10, 36-50
    • (2009) Obes. Rev. , vol.10 , pp. 36-50
    • Hession, M.1    Rolland, C.2    Kulkarni, U.3    Wise, A.4    Broom, J.5
  • 17
    • 55149108075 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: The potential role of nutritional management
    • Leclercq, I. A., and Horsmans, Y. (2008) Nonalcoholic fatty liver disease: the potential role of nutritional management. Curr. Opin. Clin. Nutr. Metab. Care 11, 766-773
    • (2008) Curr. Opin. Clin. Nutr. Metab. Care , vol.11 , pp. 766-773
    • Leclercq, I.A.1    Horsmans, Y.2
  • 18
    • 77957652786 scopus 로고    scopus 로고
    • Fructose and metabolic diseases: New findings, new questions
    • Tappy, L., Lê, K. A., Tran, C., and Paquot, N. (2010) Fructose and metabolic diseases: new findings, new questions. Nutrition 26, 1044-1049
    • (2010) Nutrition , vol.26 , pp. 1044-1049
    • Tappy, L.1    Lê, K.A.2    Tran, C.3    Paquot, N.4
  • 19
    • 84857861919 scopus 로고    scopus 로고
    • Mechanisms for insulin resistance: Common threads and missing links
    • Samuel, V. T., and Shulman, G. I. (2012) Mechanisms for insulin resistance: common threads and missing links. Cell 148, 852-871
    • (2012) Cell , vol.148 , pp. 852-871
    • Samuel, V.T.1    Shulman, G.I.2
  • 20
    • 67650831488 scopus 로고    scopus 로고
    • Insulin resistance. Prosperity's plague
    • Taubes, G. (2009) Insulin resistance. Prosperity's plague. Science 325, 256-260
    • (2009) Science , vol.325 , pp. 256-260
    • Taubes, G.1
  • 22
    • 40549135297 scopus 로고    scopus 로고
    • Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: Lessons from genetically engineered mice
    • DOI 10.1172/JCI34275
    • Postic, C., and Girard, J. (2008) Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice. J. Clin. Investig. 118, 829-838 (Pubitemid 351364588)
    • (2008) Journal of Clinical Investigation , vol.118 , Issue.3 , pp. 829-838
    • Postic, C.1    Girard, J.2
  • 23
    • 0032693382 scopus 로고    scopus 로고
    • Validation of a new procedure to determine plasma fatty acid concentration and isotopic enrichment
    • Patterson, B. W., Zhao, G., Elias, N., Hachey, D. L., and Klein, S. (1999) Validation of a new procedure to determine plasma fatty acid concentration and isotopic enrichment. J. Lipid Res. 40, 2118-2124 (Pubitemid 29523438)
    • (1999) Journal of Lipid Research , vol.40 , Issue.11 , pp. 2118-2124
    • Patterson, B.W.1    Zhao, G.2    Elias, N.3    Hachey, D.L.4    Klein, S.5
  • 26
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh, E. G., and Dyer, W. J. (1959) A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37, 911-917
    • (1959) Can. J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 27
    • 0032232019 scopus 로고    scopus 로고
    • Formation of lithiated adducts of glycerophosphocholine lipids facilitates their identification by electrospray ionization tandem mass spectrometry
    • Hsu, F. F., Bohrer, A., and Turk, J. (1998) Formation of lithiated adducts of glycerophosphocholine lipids facilitates their identification by electrospray ionization tandem mass spectrometry. J. Am. Soc. Mass Spectrom. 9, 516-526
    • (1998) J. Am. Soc. Mass Spectrom. , vol.9 , pp. 516-526
    • Hsu, F.F.1    Bohrer, A.2    Turk, J.3
  • 28
    • 0033404418 scopus 로고    scopus 로고
    • Structural characterization of triacylglycerols as lithiated adducts by electrospray ionization mass spectrometry using low-energy collisionally activated dissociation on a triple stage quadrupole instrument
    • DOI 10.1016/S1044-0305(99)00035-5, PII S1044030599000355
    • Hsu, F. F., and Turk, J. (1999) Structural characterization of triacylglycerols as lithiated adducts by electrospray ionization mass spectrometry using low-energy collisionally activated dissociation on a triple stage quadrupole instrument. J. Am. Soc. Mass Spectrom. 10, 587-599 (Pubitemid 34475125)
    • (1999) Journal of the American Society for Mass Spectrometry , vol.10 , Issue.7 , pp. 587-599
    • Hsu, F.-F.1    Turk, J.2
  • 29
    • 0034487745 scopus 로고    scopus 로고
    • Characterization of phosphatidylinositol, phosphatidylinositol-4- phosphate, and phosphatidylinositol-4,5-bisphosphate by electrospray ionization tandem mass spectrometry: A mechanistic study
    • DOI 10.1016/S1044-0305(00)00172-0, PII S1044030500001720
    • Hsu, F. F., and Turk, J. (2000) Characterization of phosphatidylinositol, phosphatidylinositol-4-phosphate, and phosphatidylinositol-4,5-bisphosphate by electrospray ionization tandem mass spectrometry: a mechanistic study. J. Am. Soc. Mass Spectrom. 11, 986-999 (Pubitemid 34546669)
    • (2000) Journal of the American Society for Mass Spectrometry , vol.11 , Issue.11 , pp. 986-999
    • Hsu, F.-F.1    Turk, J.2
  • 30
    • 70449774815 scopus 로고    scopus 로고
    • The DHR96 nuclear receptor controls triacylglycerol homeostasis in Drosophila
    • Sieber, M. H., and Thummel, C. S. (2009) The DHR96 nuclear receptor controls triacylglycerol homeostasis in Drosophila. Cell Metab. 10, 481-490
    • (2009) Cell Metab. , vol.10 , pp. 481-490
    • Sieber, M.H.1    Thummel, C.S.2
  • 31
    • 22544480378 scopus 로고    scopus 로고
    • "New" hepatic fat activates PPARα to maintain glucose, lipid, and cholesterol homeostasis
    • DOI 10.1016/j.cmet.2005.04.002, PII S1550413105001105
    • Chakravarthy, M. V., Pan, Z., Zhu, Y., Tordjman, K., Schneider, J. G., Coleman, T., Turk, J., and Semenkovich, C. F. (2005) "New" hepatic fat activates PPARγ to maintain glucose, lipid, and cholesterol homeostasis. Cell Metab. 1, 309-322 (Pubitemid 43977168)
    • (2005) Cell Metabolism , vol.1 , Issue.5 , pp. 309-322
    • Chakravarthy, M.V.1    Pan, Z.2    Zhu, Y.3    Tordjman, K.4    Schneider, J.G.5    Coleman, T.6    Turk, J.7    Semenkovich, C.F.8
  • 33
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: Discovering splice junctions with RNA-Seq
    • Trapnell, C., Pachter, L., and Salzberg, S. L. (2009) TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 25, 1105-1111
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 35
    • 77950863893 scopus 로고    scopus 로고
    • Nontriglyceride hepatic lipotoxicity: The new paradigm for the pathogenesis of NASH
    • Neuschwander-Tetri, B. A. (2010) Nontriglyceride hepatic lipotoxicity: the new paradigm for the pathogenesis of NASH. Curr. Gastroenterol. Rep. 12, 49-56
    • (2010) Curr. Gastroenterol. Rep. , vol.12 , pp. 49-56
    • Neuschwander-Tetri, B.A.1
  • 36
    • 76049101204 scopus 로고    scopus 로고
    • Obesity as a clinical and public health problem: Is there a need for a new definition based on lipotoxicity effects?
    • Sørensen, T. I., Virtue, S., and Vidal-Puig, A. (2010) Obesity as a clinical and public health problem: is there a need for a new definition based on lipotoxicity effects? Biochim. Biophys. Acta 1801, 400-404
    • (2010) Biochim. Biophys. Acta , vol.1801 , pp. 400-404
    • Sørensen, T.I.1    Virtue, S.2    Vidal-Puig, A.3
  • 37
    • 80052586771 scopus 로고    scopus 로고
    • Profiling and quantification of Drosophila melanogaster lipids using liquid chromatography/mass spectrometry
    • Hammad, L. A., Cooper, B. S., Fisher, N. P., Montooth, K. L., and Karty, J. A. (2011) Profiling and quantification of Drosophila melanogaster lipids using liquid chromatography/mass spectrometry. Rapid Commun. Mass Spectrom. 25, 2959-2968
    • (2011) Rapid Commun. Mass Spectrom. , vol.25 , pp. 2959-2968
    • Hammad, L.A.1    Cooper, B.S.2    Fisher, N.P.3    Montooth, K.L.4    Karty, J.A.5
  • 38
    • 67749091052 scopus 로고    scopus 로고
    • Management of the metabolic syndrome and type 2 diabetes through lifestyle modification
    • Magkos, F., Yannakoulia, M., Chan, J. L., and Mantzoros, C. S. (2009) Management of the metabolic syndrome and type 2 diabetes through lifestyle modification. Annu. Rev. Nutr. 29, 223-256
    • (2009) Annu. Rev. Nutr. , vol.29 , pp. 223-256
    • Magkos, F.1    Yannakoulia, M.2    Chan, J.L.3    Mantzoros, C.S.4
  • 39
    • 77954351422 scopus 로고    scopus 로고
    • Diabetes and obesity: Therapeutic targeting and risk reduction - A complex interplay
    • Niswender, K. (2010) Diabetes and obesity: therapeutic targeting and risk reduction - a complex interplay. Diabetes Obes. Metab. 12, 267-287
    • (2010) Diabetes Obes. Metab. , vol.12 , pp. 267-287
    • Niswender, K.1
  • 40
    • 38449087713 scopus 로고    scopus 로고
    • ChREBP, a transcriptional regulator of glucose and lipid metabolism
    • DOI 10.1146/annurev.nutr.27.061406.093618
    • Postic, C., Dentin, R., Denechaud, P. D., and Girard, J. (2007) ChREBP, a transcriptional regulator of glucose and lipid metabolism. Annu. Rev. Nutr. 27, 179-192 (Pubitemid 351373354)
    • (2007) Annual Review of Nutrition , vol.27 , pp. 179-192
    • Postic, C.1    Dentin, R.2    Denechaud, P.-D.3    Girard, J.4
  • 41
    • 84255163040 scopus 로고    scopus 로고
    • The role of stearoyl-CoA desaturase in obesity insulin resistance and inflammation
    • Sampath, H., and Ntambi, J. M. (2011) The role of stearoyl-CoA desaturase in obesity, insulin resistance, and inflammation. Ann. N.Y. Acad. Sci. 1243, 47-53
    • (2011) Ann NY Acad Sci , vol.1243 , pp. 47-53
    • Sampath, H.1    Ntambi, J.M.2
  • 43
    • 0037448528 scopus 로고    scopus 로고
    • Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
    • DOI 10.1038/nature01279
    • Ashrafi, K., Chang, F. Y., Watts, J. L., Fraser, A. G., Kamath, R. S., Ahringer, J., and Ruvkun, G. (2003) Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 421, 268-272 (Pubitemid 36139130)
    • (2003) Nature , vol.421 , Issue.6920 , pp. 268-272
    • Ashrafi, K.1    Chang, F.Y.2    Watts, J.L.3    Fraser, A.G.4    Kamath, R.S.5    Ahringer, J.6    Ruvkun, G.7
  • 44
    • 0025627770 scopus 로고
    • Fat (fat) and tubby (tub): Two autosomal recessive mutations causing obesity syndromes in the mouse
    • Coleman, D. L., and Eicher, E. M. (1990) Fat (fat) and tubby (tub): two autosomal recessive mutations causing obesity syndromes in the mouse. J. Hered. 81, 424-427
    • (1990) J. Hered. , vol.81 , pp. 424-427
    • Coleman, D.L.1    Eicher, E.M.2
  • 47
  • 48
    • 3142665525 scopus 로고    scopus 로고
    • GOstat: Find statistically overrepresented Gene Ontologies with a group of genes
    • DOI 10.1093/bioinformatics/bth088
    • Beissbarth, T., and Speed, T. P. (2004) GOstat: find statistically overrepresented Gene Ontologies within a group of genes. Bioinformatics 20, 1464-1465 (Pubitemid 38931420)
    • (2004) Bioinformatics , vol.20 , Issue.9 , pp. 1464-1465
    • Beissbarth, T.1    Speed, T.P.2
  • 49
    • 67549131188 scopus 로고    scopus 로고
    • Energy homeostasis and cancer prevention: The AMP-activated protein kinase
    • Fay, J. R., Steele, V., and Crowell, J. A. (2009) Energy homeostasis and cancer prevention: the AMP-activated protein kinase. Cancer Prev. Res. 2, 301-309
    • (2009) Cancer Prev. Res. , vol.2 , pp. 301-309
    • Fay, J.R.1    Steele, V.2    Crowell, J.A.3
  • 50
    • 80052688465 scopus 로고    scopus 로고
    • Diseases and disorders associated with excess body weight
    • Knight, J. A. (2011) Diseases and disorders associated with excess body weight. Ann. Clin. Lab. Sci. 41, 107-121
    • (2011) Ann. Clin. Lab. Sci. , vol.41 , pp. 107-121
    • Knight, J.A.1
  • 51
    • 0028787750 scopus 로고
    • The effect of over- and undernutrition on cancer
    • Kritchevsky, D. (1995) The effect of over- and undernutrition on cancer. Eur. J. Cancer Prev. 4, 445-451
    • (1995) Eur. J. Cancer Prev. , vol.4 , pp. 445-451
    • Kritchevsky, D.1
  • 54
    • 2342430250 scopus 로고    scopus 로고
    • Obesity, insulin resistance, and cardiovascular disease
    • DOI 10.1210/rp.59.1.207
    • Reaven, G., Abbasi, F., and McLaughlin, T. (2004) Obesity, insulin resistance, and cardiovascular disease. Recent Prog. Horm. Res. 59, 207-223 (Pubitemid 41327152)
    • (2004) Recent Progress in Hormone Research , vol.59 , pp. 207-223
    • Reaven, G.1    Abbasi, F.2    McLaughlin, T.3
  • 55
    • 33846279755 scopus 로고    scopus 로고
    • Specialized hepatocyte-like cells regulate Drosophila lipid metabolism
    • DOI 10.1038/nature05382, PII NATURE05382
    • Gutierrez, E., Wiggins, D., Fielding, B., and Gould, A. P. (2007) Specialized hepatocyte-like cells regulate Drosophila lipid metabolism. Nature 445, 275-280 (Pubitemid 46122810)
    • (2007) Nature , vol.445 , Issue.7125 , pp. 275-280
    • Gutierrez, E.1    Wiggins, D.2    Fielding, B.3    Gould, A.P.4
  • 56
    • 34548847172 scopus 로고    scopus 로고
    • Diabetic larvae and obese flies-emerging studies of metabolism in drosophila
    • DOI 10.1016/j.cmet.2007.09.002, PII S1550413107002628
    • Baker, K. D., and Thummel, C. S. (2007) Diabetic larvae and obese fliesemerging studies of metabolism in Drosophila. Cell Metab. 6, 257-266 (Pubitemid 47450188)
    • (2007) Cell Metabolism , vol.6 , Issue.4 , pp. 257-266
    • Baker, K.D.1    Thummel, C.S.2
  • 57
    • 53849143606 scopus 로고    scopus 로고
    • Adipose tissue expandability: The metabolic problems of obesity may arise from the inability to become more obese
    • Tan, C. Y., and Vidal-Puig, A. (2008) Adipose tissue expandability: the metabolic problems of obesity may arise from the inability to become more obese. Biochem. Soc. Trans. 36, 935-940
    • (2008) Biochem. Soc. Trans. , vol.36 , pp. 935-940
    • Tan, C.Y.1    Vidal-Puig, A.2
  • 58
    • 77953356804 scopus 로고    scopus 로고
    • Gluttony, sloth and the metabolic syndrome: A roadmap to lipotoxicity
    • Unger, R. H., and Scherer, P. E. (2010) Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity. Trends Endocrinol. Metab. 21, 345-352
    • (2010) Trends Endocrinol. Metab. , vol.21 , pp. 345-352
    • Unger, R.H.1    Scherer, P.E.2
  • 65
    • 2942526828 scopus 로고    scopus 로고
    • Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease
    • DOI 10.1056/NEJMoa033179
    • Klein, S., Fontana, L., Young, V. L., Coggan, A. R., Kilo, C., Patterson, B. W., and Mohammed, B. S. (2004) Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. N. Engl. J. Med. 350, 2549-2557 (Pubitemid 38758542)
    • (2004) New England Journal of Medicine , vol.350 , Issue.25 , pp. 2549-2557
    • Klein, S.1    Fontana, L.2    Young, L.3    Coggan, A.R.4    Kilo, C.5    Patterson, B.W.6    Mohammed, B.S.7
  • 66
    • 0036310037 scopus 로고    scopus 로고
    • The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes
    • Mayerson, A. B., Hundal, R. S., Dufour, S., Lebon, V., Befroy, D., Cline, G. W., Enocksson, S., Inzucchi, S. E., Shulman, G. I., and Petersen, K. F. (2002) The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes. Diabetes 51, 797-802 (Pubitemid 34760191)
    • (2002) Diabetes , vol.51 , Issue.3 , pp. 797-802
    • Mayerson, A.B.1    Hundal, R.S.2    Dufour, S.3    Lebon, V.4    Befroy, D.5    Cline, G.W.6    Enocksson, S.7    Inzucchi, S.E.8    Shulman, G.I.9    Petersen, K.F.10
  • 67
    • 42949116365 scopus 로고    scopus 로고
    • Lipid accumulation in non-adipose tissue and lipotoxicity
    • DOI 10.1016/j.physbeh.2007.11.049, PII S0031938407004805
    • van Herpen, N. A., and Schrauwen-Hinderling, V. B. (2008) Lipid accumulation in non-adipose tissue and lipotoxicity. Physiol. Behav. 94, 231-241 (Pubitemid 351615422)
    • (2008) Physiology and Behavior , vol.94 , Issue.2 , pp. 231-241
    • Van Herpen, N.A.1    Schrauwen-Hinderling, V.B.2
  • 71
    • 36448991861 scopus 로고    scopus 로고
    • Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis
    • DOI 10.1016/j.cmet.2007.10.014, PII S155041310700335X
    • Miyazaki, M., Flowers, M. T., Sampath, H., Chu, K., Otzelberger, C., Liu, X., and Ntambi, J. M. (2007) Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis. Cell Metab. 6, 484-496 (Pubitemid 350163054)
    • (2007) Cell Metabolism , vol.6 , Issue.6 , pp. 484-496
    • Miyazaki, M.1    Flowers, M.T.2    Sampath, H.3    Chu, K.4    Otzelberger, C.5    Liu, X.6    Ntambi, J.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.