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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 8, 2013, Pages 2298-2301

Identification of pyrrolo[2,3-g]indazoles as new Pim kinase inhibitors

(6) Gavara, Laurent b Suchaud, Virginie b Nauton, Lionel b Théry, Vincent b Anizon, Fabrice a Moreau, Pascale b

a UNIVERSITÉ CLERMONT AUVERGNE (France)

b ICCF (France)

Author keywords

Indazole; Indole; Pim kinase inhibition; Pyrrolo 2,3 g indazole

Indexed keywords

ADENOSINE TRIPHOSPHATE; PROTEIN KINASE PIM 1; PROTEIN SERINE THREONINE KINASE INHIBITOR; PYRROLO[2,3 G]INDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG BINDING; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME STRUCTURE; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION;

CRYSTALLOGRAPHY, X-RAY; INDAZOLES; MODELS, MOLECULAR; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-PIM-1; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84875434710 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2013.02.074 Document Type: Article

Times cited : (27)

References (31)

1
- 84864445459
- K. Hattori, K. Yamaguchi, J. Yamaguchi, and K. Itami Tetrahedron 68 2012 7605
- (2012) Tetrahedron , vol.68 , pp. 7605
- Hattori, K.¹ Yamaguchi, K.² Yamaguchi, J.³ Itami, K.⁴

2
- 84859790153
- F. Sun, X. Feng, X. Zhao, Z.-B. Huang, and D.-Q. Shi Tetrahedron 68 2012 3851
- (2012) Tetrahedron , vol.68 , pp. 3851
- Sun, F.¹ Feng, X.² Zhao, X.³ Huang, Z.-B.⁴ Shi, D.-Q.⁵

3
- 84859567458
- P. Li, C. Wu, J. Zhao, D.C. Rogness, and F. Shi J. Org. Chem. 77 2012 3149
- (2012) J. Org. Chem. , vol.77 , pp. 3149
- Li, P.¹ Wu, C.² Zhao, J.³ Rogness, D.C.⁴ Shi, F.⁵

4
- 84862060671
- X. Xiong, Y. Jiang, and D. Ma Org. Lett. 14 2012 2552
- (2012) Org. Lett. , vol.14 , pp. 2552
- Xiong, X.¹ Jiang, Y.² Ma, D.³

5
- 84864516511
- F.-F. Yong, and Y.-C. Teo Synlett 2012 2106
- (2012) Synlett , pp. 2106
- Yong, F.-F.¹ Teo, Y.-C.²

6
- 84855831145
- L. El Kaïm, L. Grimaud, and S.R. Purumandla Synlett 2012 295
- (2012) Synlett , pp. 295
- El Kaïm, L.¹ Grimaud, L.² Purumandla, S.R.³

7
- 53749084486
- A. Schmidt, A. Beutler, and B. Snovydovych Eur. J. Org. Chem. 2008 4073
- (2008) Eur. J. Org. Chem. , pp. 4073
- Schmidt, A.¹ Beutler, A.² Snovydovych, B.³

8
- 24944564781
- H. Cerecetto, A. Gerpe, M. González, V.J. Arán, and C.O. de Ocáriz Mini-Rev. Med. Chem. 5 2005 869
- (2005) Mini-Rev. Med. Chem. , vol.5 , pp. 869
- Cerecetto, H.¹ Gerpe, A.² González, M.³ Arán, V.J.⁴ De Ocáriz, C.O.⁵

9
- 84867421937
- P.M. Lukasik, S. Elabar, F. Lam, H. Shao, X. Liu, A.Y. Abbas, and S. Wang Eur. J. Med. Chem. 57 2012 311
- (2012) Eur. J. Med. Chem. , vol.57 , pp. 311
- Lukasik, P.M.¹ Elabar, S.² Lam, F.³ Shao, H.⁴ Liu, X.⁵ Abbas, A.Y.⁶ Wang, S.⁷

10
- 84863237488
- R. Li, M.P. Martin, Y. Liu, B. Wang, R.A. Patel, J.-Y. Zhu, N. Sun, R. Pireddu, N.J. Lawrence, J. Li, E.B. Haura, S.-S. Sung, W.C. Guida, E. Schonbrunn, and S.M. Sebti J. Med. Chem. 55 2012 2474
- (2012) J. Med. Chem. , vol.55 , pp. 2474
- Li, R.¹ Martin, M.P.² Liu, Y.³ Wang, B.⁴ Patel, R.A.⁵ Zhu, J.-Y.⁶ Sun, N.⁷ Pireddu, R.⁸ Lawrence, N.J.⁹ Li, J.¹⁰ Haura, E.B.¹¹ Sung, S.-S.¹² Guida, W.C.¹³ Schonbrunn, E.¹⁴ Sebti, S.M.¹⁵

11
- 84862204027
- N. Fuchi, Y. Iura, H. Kaneko, A. Nitta, K. Suyama, H. Ueda, S. Yamaguchi, K. Nishimura, S. Fujii, Y. Sekiya, M. Yamada, and T. Takahashi Bioorg. Med. Chem. Lett. 22 2012 4358
- (2012) Bioorg. Med. Chem. Lett. , vol.22 , pp. 4358
- Fuchi, N.¹ Iura, Y.² Kaneko, H.³ Nitta, A.⁴ Suyama, K.⁵ Ueda, H.⁶ Yamaguchi, S.⁷ Nishimura, K.⁸ Fujii, S.⁹ Sekiya, Y.¹⁰ Yamada, M.¹¹ Takahashi, T.¹²

12
- 84863461469
- X. Deng, W. Zhou, E. Weisberg, J. Wang, J. Zhang, T. Sasaki, E. Nelson, J.D. Griffin, P.A. Jänne, and N.S. Gray Bioorg. Med. Chem. Lett. 22 2012 4579
- (2012) Bioorg. Med. Chem. Lett. , vol.22 , pp. 4579
- Deng, X.¹ Zhou, W.² Weisberg, E.³ Wang, J.⁴ Zhang, J.⁵ Sasaki, T.⁶ Nelson, E.⁷ Griffin, J.D.⁸ Jänne, P.A.⁹ Gray, N.S.¹⁰

13
- 84866086589
- F. Giraud, R. Akué-Gédu, L. Nauton, N. Candelon, E. Debiton, V. Théry, F. Anizon, and P. Moreau Eur. J. Med. Chem. 56 2012 225
- (2012) Eur. J. Med. Chem. , vol.56 , pp. 225
- Giraud, F.¹ Akué-Gédu, R.² Nauton, L.³ Candelon, N.⁴ Debiton, E.⁵ Théry, V.⁶ Anizon, F.⁷ Moreau, P.⁸

14
- 84858441553
- B. Letribot, R. Akué-Gédu, N.M. Santio, M. El-Ghozzi, D. Avignant, F. Cisnetti, P.J. Koskinen, A. Gautier, F. Anizon, and P. Moreau Eur. J. Med. Chem. 50 2012 304
- (2012) Eur. J. Med. Chem. , vol.50 , pp. 304
- Letribot, B.¹ Akué-Gédu, R.² Santio, N.M.³ El-Ghozzi, M.⁴ Avignant, D.⁵ Cisnetti, F.⁶ Koskinen, P.J.⁷ Gautier, A.⁸ Anizon, F.⁹ Moreau, P.¹⁰

15
- 84861182749
- R. Akué-Gédu, B. Letribot, E. Saugues, E. Debiton, F. Anizon, and P. Moreau Bioorg. Med. Chem. Lett. 22 2012 3807
- (2012) Bioorg. Med. Chem. Lett. , vol.22 , pp. 3807
- Akué-Gédu, R.¹ Letribot, B.² Saugues, E.³ Debiton, E.⁴ Anizon, F.⁵ Moreau, P.⁶

16
- 77956344582
- R. Akué-Gédu, L. Nauton, V. Théry, J. Bain, P. Cohen, F. Anizon, and P. Moreau Bioorg. Med. Chem. 18 2010 6865
- (2010) Bioorg. Med. Chem. , vol.18 , pp. 6865
- Akué-Gédu, R.¹ Nauton, L.² Théry, V.³ Bain, J.⁴ Cohen, P.⁵ Anizon, F.⁶ Moreau, P.⁷

17
- 77957833608
- L. Gavara, E. Saugues, G. Alves, E. Debiton, F. Anizon, and P. Moreau Eur. J. Med. Chem. 45 2010 5520
- (2010) Eur. J. Med. Chem. , vol.45 , pp. 5520
- Gavara, L.¹ Saugues, E.² Alves, G.³ Debiton, E.⁴ Anizon, F.⁵ Moreau, P.⁶

18
- 70350052791
- R. Akué-Gédu, E. Rossignol, S. Azzaro, S. Knapp, P. Filippakopoulos, A.N. Bullock, J. Bain, P. Cohen, M. Prudhomme, F. Anizon, and P. Moreau J. Med. Chem. 52 2009 6369
- (2009) J. Med. Chem. , vol.52 , pp. 6369
- Akué-Gédu, R.¹ Rossignol, E.² Azzaro, S.³ Knapp, S.⁴ Filippakopoulos, P.⁵ Bullock, A.N.⁶ Bain, J.⁷ Cohen, P.⁸ Prudhomme, M.⁹ Anizon, F.¹⁰ Moreau, P.¹¹

19
- 78650647009
- F. Anizon, A.A. Shtil, V.N. Danilenko, and P. Moreau Curr. Med. Chem. 17 2010 4114
- (2010) Curr. Med. Chem. , vol.17 , pp. 4114
- Anizon, F.¹ Shtil, A.A.² Danilenko, V.N.³ Moreau, P.⁴

20
- 76149130727
- T. Morwick Expert Opin. Ther. Pat. 20 2010 193
- (2010) Expert Opin. Ther. Pat. , vol.20 , pp. 193
- Morwick, T.¹

21
- 77953180976
- L. Brault, C. Gasser, F. Bracher, K. Huber, S. Knapp, and J. Schwaller Haematologica 95 2010 1004
- (2010) Haematologica , vol.95 , pp. 1004
- Brault, L.¹ Gasser, C.² Bracher, F.³ Huber, K.⁴ Knapp, S.⁵ Schwaller, J.⁶

22
- 77957967569
- N.S. Magnuson, Z. Wang, G. Ding, and R. Reeves Future Oncol. 6 2010 1461
- (2010) Future Oncol. , vol.6 , pp. 1461
- Magnuson, N.S.¹ Wang, Z.² Ding, G.³ Reeves, R.⁴

23
- 80052025089
- M. Isaac, A. Siu, and J. Jongstra Drug Resist. Update 14 2011 203
- (2011) Drug Resist. Update , vol.14 , pp. 203
- Isaac, M.¹ Siu, A.² Jongstra, J.³

24
- 3343007095
- T.L. Aho, J. Sandholm, K.J. Peltola, H.P. Mankonen, M. Lilly, and P.J. Koskinen FEBS Lett. 571 2004 43
- (2004) FEBS Lett. , vol.571 , pp. 43
- Aho, T.L.¹ Sandholm, J.² Peltola, K.J.³ Mankonen, H.P.⁴ Lilly, M.⁵ Koskinen, P.J.⁶

25
- 80051785112
- L. Gavara, F. Anizon, and P. Moreau Tetrahedron 67 2011 7330
- (2011) Tetrahedron , vol.67 , pp. 7330
- Gavara, L.¹ Anizon, F.² Moreau, P.³

26
- 36549040859
- J. Bain, L. Plater, M. Elliott, N. Shpiro, J. Hastie, H. McLauchlan, I. Klervernic, S.C. Arthur, D.R. Alessi, and P. Cohen Biochem. J. 408 2007 297
- (2007) Biochem. J. , vol.408 , pp. 297
- Bain, J.¹ Plater, L.² Elliott, M.³ Shpiro, N.⁴ Hastie, J.⁵ McLauchlan, H.⁶ Klervernic, I.⁷ Arthur, S.C.⁸ Alessi, D.R.⁹ Cohen, P.¹⁰

27
- 0027136282
- A. Sali, and T.L. Blundell J. Mol. Biol. 234 1993 779
- (1993) J. Mol. Biol. , vol.234 , pp. 779
- Sali, A.¹ Blundell, T.L.²

28
- 4444221565
- E.F. Pettersen, T.D. Goddard, C.C. Huang, G.S. Couch, D.M. Greenblatt, E.C. Meng, and T.E. Ferrin J. Comput. Chem. 25 2004 1605
- (2004) J. Comput. Chem. , vol.25 , pp. 1605
- Pettersen, E.F.¹ Goddard, T.D.² Huang, C.C.³ Couch, G.S.⁴ Greenblatt, D.M.⁵ Meng, E.C.⁶ Ferrin, T.E.⁷

29
- 33748781976
- E.C. Meng, E.F. Pettersen, G.S. Couch, C.C. Huang, and T.E. Ferrin BMC Bioinform. 7 2006 339
- (2006) BMC Bioinform. , vol.7 , pp. 339
- Meng, E.C.¹ Pettersen, E.F.² Couch, G.S.³ Huang, C.C.⁴ Ferrin, T.E.⁵

30
- 84863276609
- Z. Yang, K. Lasker, D. Schneidman-Duhovny, B. Webb, C.C. Huang, E.F. Pettersen, T.D. Goddard, E.C. Meng, A. Sali, and T.E. Ferrin J. Struct. Biol. 179 2012 269
- (2012) J. Struct. Biol. , vol.179 , pp. 269
- Yang, Z.¹ Lasker, K.² Schneidman-Duhovny, D.³ Webb, B.⁴ Huang, C.C.⁵ Pettersen, E.F.⁶ Goddard, T.D.⁷ Meng, E.C.⁸ Sali, A.⁹ Ferrin, T.E.¹⁰

31
- 84875460609
- 1699 South Hanley Rd., St. Louis, Missouri 63144, USA
- Sybylx2.0, Tripos International, 1699 South Hanley Rd., St. Louis, Missouri 63144, USA.
- Sybylx2.0, Tripos International

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