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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 14, 2012, Pages 4579-4584

An amino-indazole scaffold with spectrum selective kinase inhibition of FLT3, PDGFRα and kit

(10) Deng, Xianming a,b Zhou, Wenjun a,b Weisberg, Ellen a Wang, Jinhua a,b Zhang, Jianming a,b Sasaki, Takaaki a Nelson, Erik a Griffin, James D a Jänne, Pasi A a Gray, Nathanael S a,b

a DANA FARBER CANCER INSTITUTE (United States)

b HARVARD MEDICAL SCHOOL (United States)

Author keywords

Amino indazole; Type II kinase inhibitor

Indexed keywords

3 [3 (CYCLOPROPANECARBOXAMIDO) 1H INDAZOL 6 YL]BENZOATE; 3 AMINO 1H INDAZOL 6 YL BENZAMIDE DERIVATIVE; 3 AMINOINDAZOLE; 6 BROMO N METHYL 1H INDAZOL 3 AMINE; CD135 ANTIGEN; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEIN KINASE INHIBITOR; STEM CELL FACTOR; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; DRUG CONFORMATION; DRUG INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL LINE; FMS-LIKE TYROSINE KINASE 3; INDAZOLES; MICE; MODELS, MOLECULAR; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-KIT; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; STRUCTURE-ACTIVITY RELATIONSHIP;

PYRONIA TITHONUS;

EID: 84863461469 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.05.107 Document Type: Article

Times cited : (14)

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