ICA-105574 interacts with a common binding site to elicit opposite effects on inactivation gating of EAG and ERG potassium channels

Molecular Pharmacology

Volumn 83, Issue 4, 2013, Pages 805-813

  Garg, Vivek ^a   Stary Weinzinger, Anna ^b   Sanguinetti, Michael C ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITRO N [4 PHENOXYPHENYL] BENZAMIDE; POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CHANNEL GATING; CHEMICAL PHENOMENA; CHIMERA; CLINICAL ASSESSMENT; EVOKED RESPONSE AUDIOMETRY; HUMAN; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; BENZAMIDES; BINDING SITES; ETHER-A-GO-GO POTASSIUM CHANNELS; FEMALE; HUMANS; ION CHANNEL GATING; MOLECULAR SEQUENCE DATA; POTASSIUM CHANNEL BLOCKERS; XENOPUS LAEVIS;

EID: 84875428579     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.112.084384     Document Type: Article

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