The Herbal Drug Melampyrum pratense L. (Koch): Isolation and Identification of Its Bioactive Compounds Targeting Mediators of Inflammation

Evidence-based Complementary and Alternative Medicine

Volumn 2013, Issue , 2013, Pages

  Vogl, S ^a   Atanasov, A G ^a   Binder, M ^b   Bulusu, M ^b   Zehl, M ^a   Fakhrudin, N ^a,c   Heiss, E H ^a   Picker, P ^a   Wawrosch, C ^a   Saukel, J ^a   Reznicek, G ^a   Urban, E ^a   Bochkov, V ^b   Dirsch, V M ^a   Kopp, B ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c GADJAH MADA UNIVERSITY   (Indonesia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; APIGENIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FLAVONOID; GALACTITOSIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; IRIDOID; LIPOPOLYSACCHARIDE; LUNULARIN; LUTEOLIN; MELAMPYRUM PRATENSE EXTRACT; MUSSAENOSIDE; PHENOL DERIVATIVE; PLANT EXTRACT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ISOLATION; DRUG SCREENING; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MELAMPYRUM PRATENSE; OROBANCHACEAE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 84875409183     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2013/395316     Document Type: Article

References (50)

1. Gerlach S., Saukel J., Kubelka W., Pflanzen in der österreichischen Volksmedizin. Die VOLKSMED-DATENBANK. Scientia Pharmaceutica 2006 74 supplement 1 36
2. Mogoşan C., Munteanu M. F., A comparative study on antiinflammatory effect of the tinctures from Melampyrum bihariense Kern and Melapyrum cristatum L. (scrophulariaceae). Farmacia 2008 56 4 389 392 2-s2.0-49749090789
3. Maloney B., Traditional Herbal Cures in Country Cavan. Part 1 1972 1 1st Holywood, Calif, USA Ulster Folklife
4. Hayden M. S., Ghosh S., NF- B in immunobiology. Cell Research 2011 21 2 223 244 10.1038/cr.2011.13
5. Lawrence T., The nuclear factor NF- B pathway in inflammation. Cold Spring Harbor Perspectives in Biology 2009 1 6 a001651 10.1101/cshperspect. a001651
6. Sethi G., Sung B., Aggarwal B. B., Nuclear factor- B activation: from bench to bedside. Experimental Biology and Medicine 2008 233 1 21 31 2-s2.0-37549004392 10.3181/0707-MR-196
7. Lawrence T., Fong C., The resolution of inflammation: anti-inflammatory roles for NF- B. International Journal of Biochemistry and Cell Biology 2010 42 4 519 523 2-s2.0-77649183653 10.1016/j.biocel.2009.12.016
8. Baggiolini M., Uguccioni M., D'Apuzzo M., Interleukin-8 and other chemokines: new perspectives in inflammation. Falk Symposium 1995 78 5 13
9. Schroeder J.-M., Interleukin 8. Advances in Neuroimmunology 1992 2 2 109 124 10.1016/S0960-5428(06)80037-9
10. Glass C. K., Ogawa S., Combinatorial roles of nuclear receptors in inflammation and immunity. Nature Reviews Immunology 2006 6 1 44 55 2-s2.0-33244482536 10.1038/nri1748 (Pubitemid 43279752)
11. Chawla A., Control of macrophage activation and function by PPARs. Circulation Research 2010 106 10 1559 1569 2-s2.0-77952997178 10.1161/CIRCRESAHA.110.216523
12. Huang W., Glass C. K., Nuclear receptors and inflammation control: molecular mechanisms and pathophysiological relevance. Arteriosclerosis, Thrombosis, and Vascular Biology 2010 30 8 1542 1549 2-s2.0-77955170550 10.1161/ATVBAHA.109.191189
13. Neve B. P., Fruchart J. C., Staels B., Role of the peroxisome proliferator-activated receptors (PPAR) in atherosclerosis. Biochemical Pharmacology 2000 60 8 1245 1250 2-s2.0-0034668205 10.1016/S0006-2952(00)00430-5
14. Fruchart J. C., Peroxisome proliferator-activated receptor-alpha (PPAR α): at the crossroads of obesity, diabetes and cardiovascular disease. Atherosclerosis 2009 205 1 1 8 2-s2.0-67449108376 10.1016/j.atherosclerosis. 2009.03.008
15. Gizard F., Bruemmer D., Transcriptional control of vascular smooth muscle cell proliferation by peroxisome proliferator-activated receptor- γ: therapeutic implications for cardiovascular diseases. PPAR Research 2008 2008 11 429123 10.1155/2008/429123
16. Gizard F., Nomiyama T., Zhao Y., Findeisen H. M., Heywood E. B., Jones K. L., Staels B., Bruemmer D., The PPAR α /p16INK4a pathway inhibits vascular smooth muscle cell proliferation by repressing cell cycle-dependent telomerase activation. Circulation Research 2008 103 10 1155 1163 2-s2.0-63849146427 10.1161/CIRCRESAHA.108.186205
17. Okayasu T., Tomizawa A., Suzuki K., Manaka K. I., Hattori Y., PPAR α activators upregulate eNOS activity and inhibit cytokine-induced NF- B activation through AMP-activated protein kinase activation. Life Sciences 2008 82 15-16 884 891 2-s2.0-41149095864 10.1016/j.lfs.2008.02.002
18. Glass C. K., Saijo K., Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells. Nature Reviews Immunology 2010 10 5 365 376 2-s2.0-77951602823 10.1038/nri2748
19. Li A. C., Glass C. K., PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis. Journal of Lipid Research 2004 45 12 2161 2173 2-s2.0-10044223533 10.1194/jlr.R400010-JLR200 (Pubitemid 39602963)
20. Pascual G., Sullivan A. L., Ogawa S., Gamliel A., Perissi V., Rosenfeld M. G., Glass C. K., Anti-inflammatory and antidiabetic roles of PPAR γ Novartis Foundation Symposium 2007 286 183 196 2-s2.0-42449160275
21. Broda B., Swiatek L., RUzyński J., Determination of aucubin in some species of the plants from family Scrophulariaceae. Acta Poloniae Pharmaceutica 1969 26 3 255 258 2-s2.0-0014460674
22. Galishevskaya E. E., Petrichenko V. M., Phenolic compounds from two Melampyrum species. Pharmaceutical Chemistry Journal 2010 44 9 497 500 2-s2.0-78650889783 10.1007/s11094-010-0501-y
23. Galishevskaya E. E., Petrichenko V. M., Skryabina E. N., Phenolic compounds of plants of the genus Melampyrum. Farmatsiya 2011 25 29
24. Suomi J., Wiedmer S. K., Jussila M., Riekkola M.-L., Determination of iridoid glycosides by micellar electrokinetic capillary chromatography-mass spectrometry with use of the partial filling technique. Electrophoresis 2001 22 12 2580 2587 (Pubitemid 32725565)
25. Wall M. E., Wani M. C., Brown D. M., Fullas F., Olwald J. B., Josephson F. F., Thornton N. M., Pezzuto J. M., Beecher C. W. W., Farnsworth N. R., Cordell G. A., Kinghorn A. D., Effect of tannins on screening of plant extracts for enzyme inhibitory activity and techniques for their removal. Phytomedicine 1996 3 3 281 285 2-s2.0-0000748770 (Pubitemid 126504570)
26. Chaudhuri R. K., Afifi-Yazar F. Ü., Sticher O., Winkler T., 13C NMR spectroscopy of naturally occurring iridoid glucosides and their acylated derivatives. Tetrahedron 1980 36 16 2317 2326 2-s2.0-0001214189
27. Ersoz T., Yalcin F. N., Tasdemir D., Sticher O., Calis I., Iridoid and lignan glucosides from Bellardia trixago (L.) All. Turkish Journal of Medical Sciences 1998 28 397 400
28. Giessrigl B., Yazici G., Teichmann M., Effects of Scrophularia extracts on tumor cell proliferation, death and intravasation through lymphoendothelial cell barriers. International Journal of Oncology 2012 40 6 2063 2074
29. Rozema E., Atanasov A. G., Fakhrudin N., Selected extracts of Chinese Herbal Medicines: their effect on NF- B, PPAR α and PPAR γ and the respective bioactive compounds. Evidence-Based Complementary and Alternative Medicine 2012 2012 10 983023 10.1155/2012/983023
30. Chang M. W.-F., Grillari J., Mayrhofer C., Fortschegger K., Allmaier G., Marzban G., Katinger H., Voglauer R., Comparison of early passage, senescent and hTERT immortalized endothelial cells. Experimental Cell Research 2005 309 1 121 136 2-s2.0-23944496667 10.1016/j.yexcr.2005.05.002 (Pubitemid 41191229)
31. Desvergne B., Wahli W., Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocrine Reviews 1999 20 5 649 688 2-s2.0-0033305213 (Pubitemid 30650602)
32. n Datenbank mittels ESI-Ionenfallen-Massenspektrometrie [M.S. thesis] 2011 Vienna, Austria Department of Pharmacognosy, University of Vienna
33. Suomi J., Wiedmer S. K., Jussila M., Riekkola M. L., Analysis of eleven iridoid glycosides by micellar electrokinetic capillary chromatography (MECC) and screening of plant samples by partial filling (MECC)-electrospray ionisation mass spectrometry. Journal of Chromatography A 2002 970 1-2 287 296 2-s2.0-0037073093 10.1016/S0021-9673(02)00381-3 (Pubitemid 35286584)
34. Jeong H.-J., Koo H. N., Na H. J., Kim M. S., Hong S. H., Eom J. W., Kim K. S., Shin T. Y., Kim H. M., Inhibition of TNF- α and IL-6 production by aucubin through blockade of NF- B activation in RBL-2H3 mast cells. Cytokine 2002 18 5 252 259 2-s2.0-0036037498 10.1006/cyto.2002.0894 (Pubitemid 35007485)
35. Chen C.-C., Chow M. P., Huang W. C., Lin Y. C., Chang Y. J., Flavonoids inhibit tumor necrosis factor- α -induced up-regulation of intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells through activator protein-1 and nuclear factor- B: structure-activity relationships. Molecular Pharmacology 2004 66 3 683 693 2-s2.0-4944228697 (Pubitemid 39329268)
36. Choi J.-S., Choi Y. J., Park S. H., Kang J. S., Kang Y. H., Flavones mitigate tumor necrosis factor- α -induced adhesion molecule upregulation in cultured human endothelial cells: role of nuclear factor- B. Journal of Nutrition 2004 134 5 1013 1019 2-s2.0-2442530445 (Pubitemid 38619932)
37. Comalada M., Ballester I., Bailón E., Sierra S., Xaus J., Gálvez J., Medina F. S. D., Zarzuelo A., Inhibition of pro-inflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: analysis of the structure-activity relationship. Biochemical Pharmacology 2006 72 8 1010 1021 2-s2.0-33748580218 10.1016/j.bcp.2006.07.016 (Pubitemid 44374465)
38. Funakoshi-Tago M., Nakamura K., Tago K., Mashino T., Kasahara T., Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin. International Immunopharmacology 2011 11 9 1150 1159 10.1016/j.intimp.2011.03.012
39. Kim E.-K., Kwon K.-B., Song M.-Y., Flavonoids protect against cytokine-induced pancreatic beta-cell damage through suppression of nuclear factor kappaB activation. Pancreas 2007 35 4 e1 e9 (Pubitemid 350307390)
40. Ruiz P. A., Haller D., Functional diversity of flavonoids in the inhibition of the proinflammatory NF- B, IRF, and Akt signaling pathways in murine intestinal epithelial cells. Journal of Nutrition 2006 136 3 664 671 2-s2.0-33644847672 (Pubitemid 43363751)
41. Tahanian E., Sanchez L. A., Shiao T. C., Roy R., Annabi B., Flavonoids targeting of I B phosphorylation abrogates carcinogen-induced MMP-9 and COX-2 expression in human brain endothelial cells. Drug Design, Development and Therapy 2011 5 299 309
42. Chirumbolo S., The role of quercetin, flavonols and flavones in modulating inflammatory cell function. Inflammation and Allergy 2010 9 4 263 285 2-s2.0-79751471302
43. Ueda H., Yamazaki C., Yamazaki M., A hydroxyl group of flavonoids affects oral anti-inflammatory activity and inhibition of systemic tumor necrosis factor- α production. Bioscience, Biotechnology and Biochemistry 2004 68 1 119 125 2-s2.0-4544254544 10.1271/bbb.68.119 (Pubitemid 39251573)
44. Seelinger G., Merfort I., Schempp C. M., Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin. Planta Medica 2008 74 14 1667 1677 2-s2.0-57149103144 10.1055/s-0028-1088314
45. Kang O.-H., Choi J. G., Lee J. H., Kwon D. Y., Luteolin isolated from the flowers of Lonicera japonica suppresses inflammatory mediator release by blocking NF- B and MAPKs activation pathways in HMC-1 cells. Molecules 2010 15 1 385 398 2-s2.0-75749096276 10.3390/molecules15010385
46. Lu Z.-Q., Fan P. H., Ji M., Lou H. X., Terpenoids and bisbibenzyls from Chinese liverworts Conocephalum conicum and Dumortiera hirsuta. Journal of Asian Natural Products Research 2006 8 1-2 187 192 2-s2.0-33745094432 10.1080/1028602042000325537 (Pubitemid 43879883)
47. Ludwiczuk A., Komala I., Pham A., Bianchini J. P., Raharivelomanana P., Asakawa Y., Volatile components from selected Tahitian liverworts. Natural Product Communications 2009 4 10 1387 1392 2-s2.0-73449120787
48. Zhou K., Wu B., Zhuang Y., Ding L., Liu Z., Qiu F., Chemical constituents of fresh celery. Zhongguo Zhongyao Zazhi 2009 34 12 1512 1515 2-s2.0-70349108349
49. Syah Y. M., Achmad S. A., Ghisalberti E. L., Hakim E. H., Makmur L., Soekamto N. H., A stilbene dimer, andalasin B, from the root trunk of Morus macroura. Journal of Chemical Research 2004 5 339 340 2-s2.0-3142544232
50. Ramos F. A., Takaishi Y., Shirotori M., Kawaguchi Y., Tsuchiya K., Shibata H., Higuti T., Tadokoro T., Takeuchi M., Antibacterial and antioxidant activities of quercetin oxidation products from yellow onion (Allium cepa) skin. Journal of Agricultural and Food Chemistry 2006 54 10 3551 3557 2-s2.0-33744899306 10.1021/jf060251c (Pubitemid 43844180)