메뉴 건너뛰기




Volumn 40, Issue 6, 2012, Pages 2063-2074

Effects of Scrophularia extracts on tumor cell proliferation, death and intravasation through lymphoendothelial cell barriers

Author keywords

Cell death; Cell proliferation; Intravasation; Oncogenes; Scrophularia lucida

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYC PROTEIN; PLANT EXTRACT; SCROPHULARIA FLORIBUNDA EXTRACT; SCROPHULARIA LIBANOTICA EXTRACT; SCROPHULARIA LUCIDA EXTRACT; SCROPHULARIA PEREGRINA EXTRACT; SCROPHULARIA PINARDII EXTRACT; UNCLASSIFIED DRUG;

EID: 84861788398     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1388     Document Type: Article
Times cited : (28)

References (59)
  • 2
    • 33748604037 scopus 로고    scopus 로고
    • Medicinal plants from Peru: A review of plants as potential agents against cancer
    • Gonzales GF and Valerio LG Jr: Medicinal plants from Peru: a review of plants as potential agents against cancer. Anticancer Agents Med Chem 6: 429-444, 2006. (Pubitemid 44377777)
    • (2006) Anti-Cancer Agents in Medicinal Chemistry , vol.6 , Issue.5 , pp. 429-444
    • Gonzales, G.F.1    Valerio Jr., L.G.2
  • 3
    • 23044490704 scopus 로고    scopus 로고
    • Plants as a source of anti-cancer agents
    • DOI 10.1016/j.jep.2005.05.011, PII S0378874105003259, Perspectives of Ethnopharmacology
    • Cragg GM and Newman DJ: Plants as a source of anti-cancer agents. J Ethophrmacol 100: 72-79, 2005. (Pubitemid 41073525)
    • (2005) Journal of Ethnopharmacology , vol.100 , Issue.1-2 , pp. 72-79
    • Cragg, G.M.1    Newman, D.J.2
  • 4
    • 0033659280 scopus 로고    scopus 로고
    • Antineoplastic agents fom natural sources: Achievements and future directions
    • Cragg GM and Newman DJ: Antineoplastic agents fom natural sources: achievements and future directions. Expert Opin Investig Drugs 9: 2783-2797, 2000.
    • (2000) Expert Opin Investig Drugs , vol.9 , pp. 2783-2797
    • Cragg, G.M.1    Newman, D.J.2
  • 5
    • 34247109045 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the last 25 years
    • DOI 10.1021/np068054v
    • Newman DJ and Cragg GM: Natural products as sources of new drugs over the last 25 years. J Nat Prod 70: 461-477, 2007. (Pubitemid 46595760)
    • (2007) Journal of Natural Products , vol.70 , Issue.3 , pp. 461-477
    • Newman, D.J.1    Cragg, G.M.2
  • 6
    • 0004075512 scopus 로고    scopus 로고
    • Istanbul University Press, Faculty of Pharmacy
    • Baytop T: Türkiyede Bitkiler ile Tedavi. Istanbul University Press, Faculty of Pharmacy, p3255, 1999.
    • (1999) Türkiyede Bitkiler Ile Tedavi , pp. 3255
    • Baytop, T.1
  • 7
    • 84861765556 scopus 로고    scopus 로고
    • National Library, manuscript collection, Vienna, Austria
    • Vienna Dioscurides, 6th century, National Library, manuscript collection, Vienna, Austria.
    • Vienna Dioscurides, 6th Century
  • 8
    • 0036210507 scopus 로고    scopus 로고
    • Biologically active substances from the genus Scrophularia
    • DOI 10.1076/phbi.40.1.45.5864
    • Galindez J, Diaz-Lanza AM and Fernandez-Metallano L: Biologically active substances from the genus Scrophularia. Pharmaceutical Biol 40: 45-59, 2002. (Pubitemid 34264345)
    • (2002) Pharmaceutical Biology , vol.40 , Issue.1 , pp. 45-59
    • De Santos, G.J.1    Diaz, L.A.M.2    Matellano, L.F.3
  • 9
    • 0001616960 scopus 로고
    • Phenylpropanoid glycosides isolated from Scrophularia scopolii
    • Çalis I, Gross GA and Sticher O: Phenylpropanoid glycosides isolated from Scrophularia scopolii. Phytochemistry 26: 2057-2061, 1987.
    • (1987) Phytochemistry , vol.26 , pp. 2057-2061
    • Çalis, I.1    Gross, G.A.2    Sticher, O.3
  • 10
    • 19544372594 scopus 로고    scopus 로고
    • A sugar ester and an iridoid glycoside from Scrophularia ningpoensis
    • DOI 10.1016/j.phytochem.2005.03.023, PII S003194220500138X
    • Nguyen AT, Fontaine J, Malonne H, Claeys M, Luhmer M and Duez P: A sugar ester and an iridoid glycoside from Scrophularia ningpoensis. Phytochemistry 66: 1186-1191, 2005. (Pubitemid 40728316)
    • (2005) Phytochemistry , vol.66 , Issue.10 , pp. 1186-1191
    • Nguyen, A.-T.1    Fontaine, J.2    Malonne, H.3    Claeys, M.4    Luhmer, M.5    Duez, P.6
  • 12
    • 1542358723 scopus 로고    scopus 로고
    • Phenylpropanoid glycosides from Scrophularia scorodonia: In vitro anti-inflammatory activity
    • DOI 10.1016/j.lfs.2003.10.008, PII S0024320504000451
    • Díaz AM, Abad MJ, Fernández L, Silván AM, De Santos J and Bermejo P: Phenylpropanoid glycosides from Scrophularia scorodonia: in vitro anti-inflammatory activity. Life Sci 74: 2515-2526, 2004. (Pubitemid 38317116)
    • (2004) Life Sciences , vol.74 , Issue.20 , pp. 2515-2526
    • Diaz, A.M.1    Abad, M.J.2    Fernandez, L.3    Silvan, A.M.4    De Santos, J.5    Bermejo, P.6
  • 25
    • 0033058950 scopus 로고    scopus 로고
    • Increase of BCNU sensitivity by wt-p53 gene therapy in glioblastoma lines depends on the administration schedule
    • DOI 10.1038/sj.gt.3300935
    • Biroccio A, del Bufalo D, Ricca A, D'Angelo C, D'Orazi G, Sacchi A, Soddu S and Zupi G: Increase of BCNU sensitivity by wt-p53 gene therapy in glioblastoma lines depends on the administration schedule. Gene Ther 6: 1064-1072, 1999. (Pubitemid 29295212)
    • (1999) Gene Therapy , vol.6 , Issue.6 , pp. 1064-1072
    • Biroccio, A.1    Del, B.D.2    Ricca, A.3    D'Angelo, C.4    D'Orazi, G.5    Sacchi, A.6    Soddu, S.7    Zupi, G.8
  • 26
    • 12344275337 scopus 로고    scopus 로고
    • Cip/WAF1 activation is an important factor for the ERK pathway dependent anti-proliferation of colorectal cancer cells
    • Park KS, Jeon SH, Oh JW and Choi KY: P21Cip/WAF1 activation is an important factor for the ERK pathway dependent anti-proliferation of colorectal cancer cells. Exp Mol Med 36: 557-562, 2004. (Pubitemid 40129178)
    • (2004) Experimental and Molecular Medicine , vol.36 , Issue.6 , pp. 557-562
    • Park, K.-S.1    Jeon, S.H.2    Oh, J.-W.3    Choi, K.-Y.4
  • 27
    • 2442651763 scopus 로고    scopus 로고
    • waf1/cip1 by activation of mitogen-activated protein/ extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway
    • DOI 10.1158/0008-5472.CAN-03-3741
    • Facchinetti MM, De Siervi A, Toskos D and Senderowicz AM: UCN-01-induced cell cycle arrest requires the transcriptional induction of p21(waf1/cip1) by activation of mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal regulated kinase pathway. Cancer Res 64: 3629-3637, 2004. (Pubitemid 38657942)
    • (2004) Cancer Research , vol.64 , Issue.10 , pp. 3629-3637
    • Facchinetti, M.M.1    De Siervi, A.2    Toskos, D.3    Senderowicz, A.M.4
  • 28
    • 34247501302 scopus 로고    scopus 로고
    • Activation and nuclear translocation of ERK in response to ligand-dependent and -independent stimuli in liver and gill cells from rainbow trout
    • DOI 10.1242/jeb.02719
    • Ebner HL, Blatzer M, Nawaz M and Krumschnabel G: Activation and nuclear translocation of Erk in response to ligand-dependent and -independent stimuli in liver and gill cells from rainbow trout. J Exp Biol 210: 1036-1045, 2007. (Pubitemid 46650607)
    • (2007) Journal of Experimental Biology , vol.210 , Issue.6 , pp. 1036-1045
    • Ebner, H.L.1    Blatzer, M.2    Nawaz, M.3    Krumschnabel, G.4
  • 30
    • 0028818395 scopus 로고
    • Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates Max protein
    • Zervos AS, Faccio L, Gatto JP, Kyriakis JM and Brent R: Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates Max protein. Proc Natl Acad Sci USA 92: 10531-1054, 1995.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 10531-11054
    • Zervos, A.S.1    Faccio, L.2    Gatto, J.P.3    Kyriakis, J.M.4    Brent, R.5
  • 31
    • 0043066731 scopus 로고    scopus 로고
    • Regulating mammalian checkpoints through Cdc25 inactivation
    • DOI 10.1038/sj.embor.embor887
    • Donzelli M and Draetta GF: Regulating mammalian checkpoints through Cdc25 inactivation. EMBO Rep 4: 671-677, 2003. (Pubitemid 36974751)
    • (2003) EMBO Reports , vol.4 , Issue.7 , pp. 671-677
    • Donzelli, M.1    Draetta, G.F.2
  • 32
    • 0035848819 scopus 로고    scopus 로고
    • The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
    • DOI 10.1038/35071124
    • Falck J, Mailand N, Syljuasen RG, Bartek J and Lukas J: The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 410: 842-847, 2001. (Pubitemid 32303786)
    • (2001) Nature , vol.410 , Issue.6830 , pp. 842-847
    • Falck, J.1    Mailand, N.2    Syljuasen, R.G.3    Bartek, J.4    Lukas, J.5
  • 34
    • 0032905924 scopus 로고    scopus 로고
    • C-Myc target genes involved in cell growth, apoptosis and metabolism
    • Dang CV: C-Myc target genes involved in cell growth, apoptosis and metabolism. Mol Cell Biol 19: 1-11, 1999.
    • (1999) Mol Cell Biol , vol.19 , pp. 1-11
    • Dang, C.V.1
  • 35
    • 27544468372 scopus 로고    scopus 로고
    • The Fos family of transcription factors and their role in tumourigenesis
    • Milde-Langosch K: The Fos family of transcription factors and their role in tumourigenesis. Eur J Cancer 41: 2449-2461, 2005
    • (2005) Eur J Cancer , vol.41 , pp. 2449-2461
    • Milde-Langosch, K.1
  • 36
    • 0033925204 scopus 로고    scopus 로고
    • Fos family members: Regulation, structure and role in oncogenic transformation
    • Tulchinsky E: Fos family members: regulation, structure and role in oncogenic transformation. Histol Histopathol 15: 921-928, 2000.
    • (2000) Histol Histopathol , vol.15 , pp. 921-928
    • Tulchinsky, E.1
  • 37
    • 0027973061 scopus 로고
    • CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1beta-converting enzyme
    • Fernandes-Alnemri T, Litwack G and Alnemri ES: CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-concerting enzyme. J Biol Chem 269: 30761-30764, 1994. (Pubitemid 24377553)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.49 , pp. 30761-30764
    • Fernandes-Alnemri, T.1    Litwack, G.2    Alnemri, E.S.3
  • 39
    • 0030600536 scopus 로고    scopus 로고
    • Different cleavage pattern for poly(ADP-ribose) polymerase during necrosis and apoptosis in HL-60 cells
    • DOI 10.1006/bbrc.1996.1889
    • Shah GM, Shah RG and Poirier GG: Different cleavage pattern for poly(ADP-Ribose) polymerase during necrosis and apoptosis in HL-60 cells. Biochem Biophys Res Commun 229: 838-844, 1996. (Pubitemid 27035804)
    • (1996) Biochemical and Biophysical Research Communications , vol.229 , Issue.3 , pp. 838-844
    • Shah, G.M.1    Shah, R.G.2    Poirier, G.G.3
  • 40
    • 0031819578 scopus 로고    scopus 로고
    • Distinct cleavage products of nuclear proteins in apoptosis and necrosis revealed by autoantibody probes
    • Casiano CA, Ochs RL and Tan EM: Distinct cleavage products of nuclear proteins in apoptosis and necrosis revealed by autoantibody probes. Cell Death Differ 5: 183-190, 1998. (Pubitemid 28356555)
    • (1998) Cell Death and Differentiation , vol.5 , Issue.2 , pp. 183-190
    • Casiano, C.A.1    Ochs, R.L.2    Tan, E.M.3
  • 41
    • 0034949086 scopus 로고    scopus 로고
    • Characterization of the necrotic cleavage of poly (ADP-ribose) polymerase (PARP-1): Implication of lysosomal proteases
    • DOI 10.1038/sj.cdd.4400851
    • Gobell S, Boucher CC, Nadeau D and Poirier GG: Characterization of the necrotic cleavage of poly(ADP-ribose) polymerase (PARP-1): implication of lysosomal proteases. Cell Death Differ 8: 588-594, 2001. (Pubitemid 32586595)
    • (2001) Cell Death and Differentiation , vol.8 , Issue.6 , pp. 588-594
    • Gobeil, S.1    Boucher, C.C.2    Nadeau, D.3    Poirier, G.G.4
  • 42
    • 0033831784 scopus 로고    scopus 로고
    • Trimidox, an inhibitor of ribonucleotide reductase, induces apoptosis and activates caspases in HL-60 promyelocytic leukemia cells
    • Fritzer-Szekeres M, Grusch M, Luxbacher C, Horvath Z, Krupitza G, Elford HL and Szekeres T: Trimidox, an inhibitor of ribonucleotide reductase, induces apoptosis and activates caspases in HL-60 promyelocytic leukemia cells. Exp Hematol 28: 924-930, 2000.
    • (2000) Exp Hematol , vol.28 , pp. 924-930
    • Fritzer-Szekeres, M.1    Grusch, M.2    Luxbacher, C.3    Horvath, Z.4    Krupitza, G.5    Elford, H.L.6    Szekeres, T.7
  • 43
    • 0022399572 scopus 로고
    • Monoclonal antibodies specific for an acetylated form of alpha-tubulin recognize the antigen in cilia and flagella from a variety of organisms
    • DOI 10.1083/jcb.101.6.2085
    • Piperno G and Fuller M: Monoclonal antibodies specific for an acetylated form of alpha-tubulin recognize the antigen in cilia and flagella from a variety of organisms. J Cell Biol 101: 2085-2094, 1985. (Pubitemid 16169938)
    • (1985) Journal of Cell Biology , vol.101 , Issue.6 , pp. 2085-2094
    • Piperno, G.1    Fuller, M.T.2
  • 45
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D and Weinberg RA: The hallmarks of cancer. Cell 100: 57-70, 2000. (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 46
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D and Weinberg RA: Hallmarks of cancer: the next generation. Cell 144: 646-674, 2011.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 49
    • 23144464363 scopus 로고    scopus 로고
    • Transcriptional regulation and transformation by Myc proteins
    • DOI 10.1038/nrm1703
    • Adhikary S and Eilers M: Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 6: 635-645, 2005. (Pubitemid 41081267)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.8 , pp. 635-645
    • Adhikary, S.1    Eilers, M.2
  • 50
    • 0027758631 scopus 로고
    • Chromosomal translocations in leukaemia
    • Gauwerky CE and Croce CM: Chromosomal translocations in leukaemia. Semin Cancer Biol 4: 333-340, 1993. (Pubitemid 2028597)
    • (1993) Seminars in Cancer Biology , vol.4 , Issue.6 , pp. 333-340
    • Gauwerky, C.E.1    Croce, C.M.2
  • 52
    • 33644545050 scopus 로고    scopus 로고
    • Activated Src abrogates the myc requirement for the G0/G1 transition but not for the G1/S transition
    • Prathapam T, Tegen S, Oskarsson T, Trumpp A and Martin GS: Activated Src abrogates the myc requirement for the G0/G1 transition but not for the G1/S transition. Proc Natl Acad Sci USA 103: 2695-2700, 2006.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2695-2700
    • Prathapam, T.1    Tegen, S.2    Oskarsson, T.3    Trumpp, A.4    Martin, G.S.5
  • 53
    • 41149113439 scopus 로고    scopus 로고
    • c-Myc depletion inhibits proliferation of human tumor cells at various stages of the cell cycle
    • DOI 10.1038/sj.onc.1210823, PII 1210823
    • Wang H, Mannava S, Grachtchouk V, Zhuang D, Soengas MS, Gudkov AV, Prochownik EV and Nikiforov MA: c-Myc depletion inhibits proliferation of human tumor cells at various stages of cell cycle. Oncogene 27: 1905-1915, 2008. (Pubitemid 351430817)
    • (2008) Oncogene , vol.27 , Issue.13 , pp. 1905-1915
    • Wang, H.1    Mannava, S.2    Grachtchouk, V.3    Zhuang, D.4    Soengas, M.S.5    Gudkov, A.V.6    Prochownik, E.V.7    Nikiforov, M.A.8
  • 55
    • 0029002337 scopus 로고
    • Sodium butyrate inhibits c-myc splicing and interferes with signal transduction in ovarian carcinoma cells
    • Krupitza G, Harant H, Dittrich E, Szekeres T, Huber H and Dittrich C: Sodium butyrate inhibits c-myc splicing and interferes with signal transduction in ovarian carcinoma cells. Carcinogenesis 16: 1199-1205, 1995.
    • (1995) Carcinogenesis , vol.16 , pp. 1199-1205
    • Krupitza, G.1    Harant, H.2    Dittrich, E.3    Szekeres, T.4    Huber, H.5    Dittrich, C.6
  • 56
  • 57
    • 79961208848 scopus 로고    scopus 로고
    • Initial steps of metastasis: Cell i nvasion a nd endothelial t ransmigration
    • Van Zijl F, Krupitza G and Mikulits W: Initial steps of metastasis: cell i nvasion a nd endothelial t ransmigration. Mutat Res 728: 23-34, 2011.
    • (2011) Mutat Res , vol.728 , pp. 23-34
    • Van Zijl, F.1    Krupitza, G.2    Mikulits, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.