Acute responses of DNA repair proteins and StarD6 in rat hippocampus after domoic acid-induced excitotoxicity

Acta Histochemica

Volumn 115, Issue 3, 2013, Pages 234-239

  Chang, In Youb ^a   Kim, Jin Ho ^a   Cho, Kyung Won ^a   Yoon, Sang Pil ^b  

^a Chosun University   (South Korea)

^b Jeju National University School of Medicine   (South Korea)

Author keywords

H2AX; APE; BER; CA; DA; DNA damage; DNA PK; DNA PKcs; Hippocampus; NHEJ; Ogg1; Rat; StAR; StarD6; START; Str

Indexed keywords

8 HYDROXYGUANINE; DEOXYRIBONUCLEOPROTEIN; DNA; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA GLYCOSYLTRANSFERASE; DOMOIC ACID; EXCITOTOXIN; STARD6 PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; DNA BINDING PROTEIN; KAINIC ACID; STARD6 PROTEIN, RAT;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA REPAIR; DNA STRAND BREAKAGE; DOMOIC ACID INDUCED EXCITOTOXICITY; EXCITOTOXICITY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; IMMUNOREACTIVITY; MALE; NONHUMAN; PROTEIN PHOSPHORYLATION; RAT; STRATUM LACUNOSUM MOLECULARE; STRATUM RADIATUM; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; CYTOLOGY; DRUG EFFECTS; METABOLISM; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; CARRIER PROTEINS; DNA REPAIR; DNA-BINDING PROTEINS; HIPPOCAMPUS; KAINIC ACID; MALE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84875374683     PISSN: 00651281     EISSN: 16180372     Source Type: Journal    
DOI: 10.1016/j.acthis.2012.07.001     Document Type: Article

References (46)

1. Adibhatla R.M., Hatcher J.F. Altered lipid metabolism in brain injury and disorders. Subcell Biochem 2008, 49:241-268.
2. Alpy F., Tomasetto C. Give lipids a START: the StAR-related lipid transfer (START) domain in mammals. J Cell Sci 2005, 118:2791-2801.
3. Ananth C., Thameem Dheen S., Gopalakrishnakone P., Kaur C. Domoic acid-induced neuronal damage in the rat hippocampus changes in apoptosis related genes (bcl-2, bax, caspase-3) and microglial response. J Neurosci Res 2001, 66:177-190.
4. Biagini G., Baldelli E., Longo D., Pradelli L., Zini I., Rogawski M.A., et al. Endogenous neurosteroids modulate epileptogenesis in a model of temporal lobe epilepsy. Exp Neurol 2006, 20:519-524.
5. Bose H.S., Whittal R.M., Ran Y., Bose M., Baker B.Y., Miller W.L. StAR-like activity and molten globule behavior of StARD6, a male germ-line protein. Biochemistry 2008, 47:2277-2288.
6. Cavazos J.E., Jones S.M., Cross D.J. Sprouting and synaptic reorganization in the subiculum and CA1 region of the hippocampus in acute and chronic models of partial-onset epilepsy. Neuroscience 2004, 126:677-688.
7. Chang I.Y., Jeon Y.J., Jung S.M., Jang Y.H., Ahn J.B., Park K.S., et al. Does the StarD6 mark the same as the StAR in the nervous system?. J Chem Neuroanat 2010, 40:239-242.
8. Chang I.Y., Kim J.K., Lee S.M., Kim J.N., Soh J., Kim J.W., et al. The changed immunoreactivity of StarD6 after pilocarpine-induced epilepsy. Neuroreport 2009, 20:963-967.
9. Chang I.Y., Shin S.Y., Kim J.W., Yu J.M., Kim J.S., Song P.I., et al. The changed immunolocalization of START-domain containing 6 (StarD6) during the development of testes in rat perinatal hypothyroidism. Acta Histochem 2007, 109:315-321.
10. Chang I.Y., Kim J.H., Hwang G., Song P.I., Song R.J., Kim J.W., et al. Immunohistochemical detection of StarD6 in the rat nervous system. Neuroreport 2007, 18:1615-1619.
11. Chia W.J., Jenner A.M., Farooqui A.A., Ong W.Y. Changes in cytochrome P450 side chain cleavage expression in the rat hippocampus after kainite injury. Exp Brain Res 2008, 186:143-149.
12. Chowdhury D., Keogh M.C., Ishii H., Peterson C.L., Buratowski S., Lieberman J. γ-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair. Mol Cell 2005, 20:801-809.
13. Chuang Y.C., Chen S.D., Liou C.W., Lin T.K., Chang W.N., Chan S.H., et al. Contribution of nitric oxide, superoxide anion, and peroxynitrite to activation of mitochondrial apoptotic signaling in hippocampal CA3 subfield following experimental temporal lobe status epilepticus. Epilepsia 2009, 50:731-746.
14. Clark B.J. The mammalian START domain protein family in lipid transport in health and disease. J Endocrinol 2012, 212:257-275.
15. Colman J.R., Nowocin K.J., Switzer R.C., Trusk T.C., Ramsdell J.S. Mapping and reconstruction of domoic acid-induced neurodegeneration in the mouse brain. Neurotoxicol Teratol 2005, 27:753-767.
16. Coulter D.A., Mclntyre D.C., Loscher W. Animal models of limbic epilepsies: what can they tell us?. Brain Pathol 2002, 12:240-256.
17. Crowe S.L., Movsesyan V.A., Jorgensen T.J., Kondratyev A. Rapid phosphorylation of histone H2A.X. following ionotropic glutamate receptor activation. Eur J Neurosci 2006, 23:2351-2361.
18. Culmsee C., Bondada S., Mattson M.P. Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity. Brain Res Mol Brain Res 2001, 87:257-262.
19. Dinocourt C., Petanjek Z., Freund T.F., Ben-Ari Y., Exclapez M. Loss of interneurons innervating pyramidal cell dendrites and axon initial segments in the CA1 region of the hippocampus following pilocarpine-induced seizures. J Comp Neurol 2003, 459:407-425.
20. Fishel M.L., Vasko M.R., Kelley M.R. DNA repair in neurons: so if they don't divide what's to repair?. Mutat Res 2007, 614:24-36.
21. Furukawa A., Miyatake A., Ohnishi T., Ichikawa Y. Steroidogenic acute regulatory protein (StAR) transcripts constitutively expressed in adult rat central nervous system: colocalization of StAR, cytochrome P-450scc (CYP XIA1), and 3beta-hydroxysteroid dehydrogenase in the rat brain. J Neurochem 1998, 7:2231-2238.
22. Gomes C., Oh S.D., Kim J.W., Chun S.Y., Lee K.S., Kwon H.B., et al. Expression of the putative sterol binding protein Stard6 gene is male germ cell specific. Biol Reprod 2005, 72:651-658.
23. Kajitani K., Yamaguchi H., Dan Y., Furuichi M., Kang D., Nakabeppu Y. MTH1, an oxidized purine nucleoside triphosphatase, suppresses the accumulation of oxidative damage of nucleic acids in the hippocampal microglia during kainite-induced excitotoxicity. J Neurosci 2006, 26:1688-1698.
24. Jarrett S.G., Liang L.P., Hellier J.L., Staley K.J., Patel M. Mitochondrial DNA damage and impaired base excision repair during epileptogenesis. Neurobiol Dis 2008, 30:130-138.
25. Kim G.W., Noshita N., Sugawara T., Chan P.H. Early decrease in DNA repair proteins, Ku70 and Ku86, and subsequent DNA fragmentation after transient focal cerebral ischemia in mice. Stroke 2001, 32:1401-1407.
26. Liu J.X., Cao X., Tang Y.C., Liu Y., Tang F.R. CCR7, CCR8, CCR9 and CCR10 in the mouse hippocampal CA1 area and the dentate gyrus during and after pilocarpine-induced status epilepticus. J Neurochem 2007, 100:1072-1088.
27. Ma D.L., Tang Y.C., Chen P.M., Chia S.C., Jiang F.L., Burgunder J.M., et al. Reorganization of CA3 area of the mouse hippocampus after pilocarpine induced temporal lobe epilepsy with special reference to the CA3-septum pathway. J Neurosci Res 2006, 83:318-331.
28. Marti E., Blasi J., Ferrer I. Early induction of secretoneurin expression following kainic acid administration at convulsant doses in the rat and gerbil hippocampus. Hippocampus 2002, 12:174-185.
29. Martin L.J. DNA damage and repair: relevance to mechanisms of neurodegeneration. J Neuropathol Exp Neurol 2008, 67:377-387.
30. Naegele J.R. Neuroprotective strategies to avert seizure-induced neurodegeneration in epilepsy. Epilepsia 2007, 48(Suppl. 2):107-117.
31. Neema M., Navarro-Quiroga I., Chechlacz M., Gilliams-Francis K., Liu J., Lamonica K., et al. DNA damage and non-homogenous end joining in excitotoxicity: neuroprotective role of DNA-PKcs in kainic acid-induced seizures. Hippocampus 2005, 15:1057-1071.
32. Patte-Mensah C., Kappes V., Freund-Mereier M.J., Tsutsu K., Mensah-Nyagan A.G. Cellular distribution and bioactivity of the key steroidogenic enzyme, cytochrome P450 side chain cleavage, in sensory neural pathways. J Neurochem 2003, 86:1233-1246.
33. Persinger M.A., Dupont M.J. Emergence of spontaneous seizures during the year following lithium/pilocarpine-induced epilepsy and neuronal loss within the right temporal cortices. Epilepsy Behav 2004, 5:440-445.
34. Ponting C.P., Aravind L. START: a lipid-binding domain in StAR, HD-SIP and signaling proteins. Trends Biochem Sci 1999, 24:130-132.
35. Quach N., Chan T., Lu T.A., Schreiber S.S., Tan Z. Induction of DNA repair proteins, Ref-1 and XRCC1, in adult rat brain following kainic acid-induced seizures. Brain Res 2005, 1042:236-240.
36. Sanon N., Carmant L., Emond M., Congar P., Lacaille J.C. Short-term effects of kainic acid on CA1 hippocampal interneurons differently vulnerable to excitotoxicity. Epilepsia 2005, 46:837-848.
37. Sobotka T.J., Brown R., Quander D.Y., Jackson R., Smith M., Long S.A., et al. Domoic acid: neurobehavioral and neurohistological effects of low-dose exposure in adult rats. Neurotoxicol Teratol 1996, 18:659-670.
38. Soccio R.E., Breslow J.L. StAR-related lipid transfer (START) proteins: mediators of intracellular lipid metabolism. J Biol Chem 2003, 278:22183-22186.
39. Soccio R.E., Adams R.M., Romanowski M.J., Sehayek E., Burley S.K., Breslow J.L. The cholesterol-regulated StarD4 gene encodes a StAR-related lipid transfer protein with two closely related homologues, StarD5 and StarD6. Proc Natl Acad Sci USA 2002, 99:6943-6948.
40. Sugawara T., Noshita N., Lewen A., Kim G.W., Chan P.H. Neuronal expression of the DNA repair protein Ku70 after ischemic preconditioning corresponds to tolerance to global cerebral ischemia. Stroke 2001, 32:2388-2393.
41. Takahashi A., Ohnishi T. Does gammaH2AX foci formation depend on the presence of DNA double strand breaks?. Cancer Lett 2005, 229:171-179.
42. Tell G., Quadrifoglio F., Tiribelli C., Kelley M.R. The main functions of APE/Ref-1: not only a DNA repair enzyme. Antioxid Redox Signal 2009, 11:601-620.
43. Wittner L., Eross L., Czirjak S., Halasz P., Freund T.F., Magloczky Z. Surviving CA1 pyramidal cells receive intact perisomatic inhibitory input in the human epileptic hippocampus. Brain 2005, 128:138-152.
44. Wojtal K., Trojnar M.K., Czuczwar S.J. Endogenous neuroprotective factors: neurosteroids. Pharmacol Rep 2006, 58:335-340.
45. Yang E.S., Wang H., Jiang G., Nowsheen S., Fu A., Hallahan D.E., et al. Lithium-mediated protection of hippocampal cells involves enhancement of DNA-PK-dependent repair in mice. J Clin Invest 2009, 119:1124-1135.
46. Zhang S., Khanna S., Tang F.R. Patterns of hippocampal neuronal loss and axon reorganization of the dentate gyrus in the mouse pilocarpine model of temporal lobe epilepsy. J Neurosci Res 2009, 87:1135-1149.