메뉴 건너뛰기




Volumn 18, Issue 6, 1996, Pages 659-670

Domoic acid: Neurobehavioral and neurohistological effects of low-dose exposure in adult rats

Author keywords

adult rat; behavior; domoic acid; neuropathology; scopolamine pretreatment

Indexed keywords

CAFFEINE; DOMOIC ACID; SCOPOLAMINE;

EID: 18244426946     PISSN: 08920362     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0892-0362(96)00120-1     Document Type: Article
Times cited : (54)

References (60)
  • 3
    • 0011363518 scopus 로고
    • Delayed consequences of parenteral domoic acid treatment in rat brain
    • Appel, N. M.; Rapoport, S. L; O'Callaghan, J. P. Delayed consequences of parenteral domoic acid treatment in rat brain. Soc. Neurosci. Abstr. 20:1652; 1994.
    • (1994) Soc. Neurosci. Abstr. , vol.20 , pp. 1652
    • Appel, N.M.1    Rapoport, S.L.2    O'Callaghan, J.P.3
  • 5
    • 0023205572 scopus 로고
    • Pro-convulsant actions of theophylline and caffeine in the hippocampus: Implications for the management of temporal lobe epilepsy
    • Ault, B.; Olney, M. A.; Joyner, J. L.; Boyer, C. E.; Notricia, M. A.; Soroko, F. E.; Wang, C. M. Pro-convulsant actions of theophylline and caffeine in the hippocampus: Implications for the management of temporal lobe epilepsy. Brain Res. 426:93-102: 1987.
    • (1987) Brain Res. , vol.426 , pp. 93-102
    • Ault, B.1    Olney, M.A.2    Joyner, J.L.3    Boyer, C.E.4    Notricia, M.A.5    Soroko, F.E.6    Wang, C.M.7
  • 6
    • 0025870237 scopus 로고
    • Circumventricular organ origin of domoic acid-induced neuropathology and toxicology
    • Bruni, J. E.; Bose. R.; Pinsky, C.; Glavin, G. Circumventricular organ origin of domoic acid-induced neuropathology and toxicology. Brain Res. Bull. 26:419-424; 1991.
    • (1991) Brain Res. Bull. , vol.26 , pp. 419-424
    • Bruni, J.E.1    Bose, R.2    Pinsky, C.3    Glavin, G.4
  • 7
    • 0011271274 scopus 로고
    • Expanding the RfD concept to incorporate and optimize beneficial effects while preventing toxic responses from nonessential toxicants
    • October
    • Calabrese, E. J. Expanding the RfD concept to incorporate and optimize beneficial effects while preventing toxic responses from nonessential toxicants. Biological Effects of Low Level Exposures Newsletter, 4 (No. 2, October):1-10; 1995.
    • (1995) Biological Effects of Low Level Exposures Newsletter , vol.4 , Issue.2 , pp. 1-10
    • Calabrese, E.J.1
  • 8
    • 0000259231 scopus 로고
    • Long term potentiation in the hippocampus: Mechanisms of initiation and modulation by neurotransmitters
    • Collingridge, G. L. Long term potentiation in the hippocampus: Mechanisms of initiation and modulation by neurotransmitters. Trends Pharmacol. Sci. 6:407-411; 1985.
    • (1985) Trends Pharmacol. Sci. , vol.6 , pp. 407-411
    • Collingridge, G.L.1
  • 9
    • 0023915822 scopus 로고
    • Excitatory amino acid neurotransmission: NMDA receptors and Hebb-type synaptic plasticity
    • Cotman, C. W.; Monaghan, D. T.; Ganong, A. H. Excitatory amino acid neurotransmission: NMDA receptors and Hebb-type synaptic plasticity. Annu. Rev. Neurosci. 11:61-80; 1988.
    • (1988) Annu. Rev. Neurosci. , vol.11 , pp. 61-80
    • Cotman, C.W.1    Monaghan, D.T.2    Ganong, A.H.3
  • 10
    • 0024550624 scopus 로고
    • Domoic acid, the alleged "mussel toxin," might produce its neurotoxic effect through kainate receptor activation: An electrophysiological study in the dorsal hippocampus
    • Debonnel, G.; Beauchesne, L.; de Montigny, C. Domoic acid, the alleged "mussel toxin," might produce its neurotoxic effect through kainate receptor activation: An electrophysiological study in the dorsal hippocampus. Can. J. Physiol. Pharmacol. 67:29-33; 1989.
    • (1989) Can. J. Physiol. Pharmacol. , vol.67 , pp. 29-33
    • Debonnel, G.1    Beauchesne, L.2    De Montigny, C.3
  • 11
    • 0009462085 scopus 로고
    • Neurotoxic effect of domoic acid: Mediation by kainate receptor electrophysiological studies in the rat
    • Debonnel. G.: Weiss. M.; de Montigny, C. Neurotoxic effect of domoic acid: Mediation by kainate receptor electrophysiological studies in the rat. Can. Dis. Wkly. Rep. 16(Suppl. 1E):59-68; 1990.
    • (1990) Can. Dis. Wkly. Rep. , vol.16 , Issue.SUPPL. 1E , pp. 59-68
    • Debonnel, G.1    Weiss, M.2    De Montigny, C.3
  • 12
    • 0024450495 scopus 로고
    • Reduced neuroexcitatory effect of domoic acid following mossy fiber denervation of the rat dorsal hippocampus: Further evidence that toxicity of domoic acid involves kainate receptor activation
    • Debonnel. Ci.; Weiss. M.; de Montigny, C. Reduced neuroexcitatory effect of domoic acid following mossy fiber denervation of the rat dorsal hippocampus: Further evidence that toxicity of domoic acid involves kainate receptor activation. Can. J. Physiol. Pharmacol. 67:904-908; 1989.
    • (1989) Can. J. Physiol. Pharmacol. , vol.67 , pp. 904-908
    • Ci, D.1    Weiss, M.2    De Montigny, C.3
  • 13
    • 0002840628 scopus 로고
    • Nutritional deficiencies and metabolic disorders
    • Adams, J. H.; Duchen. L. W.. eds. New York: Oxford Press
    • Duchen. L. W.: Jacobs, J. M. Nutritional deficiencies and metabolic disorders. In: Adams, J. H.; Duchen. L. W.. eds. Greenfield's neuropathology, 5th ed.. New York: Oxford Press: 1992:839.
    • (1992) Greenfield's Neuropathology, 5th Ed.. , pp. 839
    • Duchen, L.W.1    Jacobs, J.M.2
  • 14
    • 0027972877 scopus 로고
    • Milacemide treatment in mice enhances acquisition of a Morris-type water maze task. Pharmacol
    • Finkelstein. J. E.; Hengemihle. J. M.; Ingram, D. K.: Petri, H. L. Milacemide treatment in mice enhances acquisition of a Morris-type water maze task. Pharmacol. Biochem. Behav. 49:707-710; 1994.
    • (1994) Biochem. Behav. , vol.49 , pp. 707-710
    • Finkelstein, J.E.1    Hengemihle, J.M.2    Ingram, D.K.3    Petri, H.L.4
  • 15
    • 0025490728 scopus 로고
    • PET studies of domoic acid poisoning in humans: Excitotoxic destruction of brain glutaminergic pathways, revealed in measurements of glucose metabolism by positron emission tomography
    • Gjedde, A.: Evans. A. C. PET studies of domoic acid poisoning in humans: Excitotoxic destruction of brain glutaminergic pathways, revealed in measurements of glucose metabolism by positron emission tomography. Can. Dis. Wkly. Rep. 16(Suppl. 1E):105109; 1990.
    • (1990) Can. Dis. Wkly. Rep. , vol.16 , Issue.SUPPL. 1E , pp. 105109
    • Gjedde, A.1    Evans, A.C.2
  • 16
    • 0025341744 scopus 로고
    • Domoic acid-induced neurovisceral toxic syndrome: Characterization of an animal model and putative antidotes
    • Glavin. G. B.; Pinsky. C.: Bose. R. Domoic acid-induced neurovisceral toxic syndrome: Characterization of an animal model and putative antidotes. Brain Res. Bull. 24:701-703: 1990.
    • (1990) Brain Res. Bull. , vol.24 , pp. 701-703
    • Glavin, G.B.1    Pinsky, C.2    Bose, R.3
  • 17
    • 0024849434 scopus 로고
    • Milacemide, a glycine prodrug, enhances performance of learning tasks in normal and amnestic rodents
    • Handelmann, G. E.; Nevins, M. E.; Mueller, L. L.; Arnolde, S. M.: Cordi, A. A. Milacemide, a glycine prodrug, enhances performance of learning tasks in normal and amnestic rodents. Pharmacol. Biochem. Behav. 34:823-828; 1989.
    • (1989) Pharmacol. Biochem. Behav. , vol.34 , pp. 823-828
    • Handelmann, G.E.1    Nevins, M.E.2    Mueller, L.L.3    Arnolde, S.M.4    Cordi, A.A.5
  • 19
    • 0028113935 scopus 로고
    • Toxicology and seafood toxins: Domoic acid
    • Iverson, F.; Truelove, J. Toxicology and seafood toxins: Domoic acid. Nat. Toxins 2:334-339; 1994.
    • (1994) Nat. Toxins , vol.2 , pp. 334-339
    • Iverson, F.1    Truelove, J.2
  • 20
    • 0024424845 scopus 로고
    • Domoic acid poisoning and mussel-associated intoxication: Preliminary investigations into the response of mice and rats to toxic mussel extract
    • Iverson, F.; Truelove, J.; Nera, E.; Tryphonas, L.; Campbell, J.; Lok, E. Domoic acid poisoning and mussel-associated intoxication: Preliminary investigations into the response of mice and rats to toxic mussel extract. Food Chem Toxicol. 27:377-384; 1989.
    • (1989) Food Chem Toxicol. , vol.27 , pp. 377-384
    • Iverson, F.1    Truelove, J.2    Nera, E.3    Tryphonas, L.4    Campbell, J.5    Lok, E.6
  • 21
    • 0025490719 scopus 로고
    • The toxicology of domoic acid administered systemically to rodents and primates
    • Iverson, F.: Truelove, J.; Tryphonas, L.; Nera, E. A. The toxicology of domoic acid administered systemically to rodents and primates. Can. Dis. Wkly. Rep. 16(Suppl. IE): 15-18; 1990.
    • (1990) Can. Dis. Wkly. Rep. , vol.16 , Issue.SUPPL. IE , pp. 15-18
    • Iverson, F.1    Truelove, J.2    Tryphonas, L.3    Nera, E.A.4
  • 22
    • 33646279925 scopus 로고
    • Steps between the induction and expression of long-term potentiation
    • Guidotti, A., ed. New York: Raven Press
    • Lynch, G.; Muller, D. Steps between the induction and expression of long-term potentiation. In: Guidotti, A., ed. Neurotoxicity of excitatory amino acids. New York: Raven Press; 1990:125-143.
    • (1990) Neurotoxicity of Excitatory Amino Acids , pp. 125-143
    • Lynch, G.1    Muller, D.2
  • 23
    • 0026631794 scopus 로고
    • Prevention of kainate-induced excitotoxicity by a purine analogue
    • MacGregor, D. G.; Stone, T. W. Prevention of kainate-induced excitotoxicity by a purine analogue. Neuroreport 3:536-538; 1992.
    • (1992) Neuroreport , vol.3 , pp. 536-538
    • MacGregor, D.G.1    Stone, T.W.2
  • 24
    • 45849094797 scopus 로고
    • Conceptual and procedural issues concerning the neurotoxicological assessment of learning and memory processes
    • Chang, L. W.. ed. New York: Mercel Dekker, Inc.
    • Mactutus, C. F. Conceptual and procedural issues concerning the neurotoxicological assessment of learning and memory processes. In: Chang, L. W.. ed. Principles of neurotoxicology. New York: Mercel Dekker, Inc.; 1994:397-441.
    • (1994) Principles of Neurotoxicology , pp. 397-441
    • Mactutus, C.F.1
  • 25
    • 0018869157 scopus 로고
    • The effect of kainic acid on cholinergic enzymes and receptors in the amygdala complex of the rat
    • McCaughran, J. A.; Genovese, F. L.; Schlechter, N. The effect of kainic acid on cholinergic enzymes and receptors in the amygdala complex of the rat. Brain Res. 199:127-133; 1980.
    • (1980) Brain Res. , vol.199 , pp. 127-133
    • McCaughran, J.A.1    Genovese, F.L.2    Schlechter, N.3
  • 26
    • 0020689254 scopus 로고
    • A possible relationship between folic acid neurotoxicity and cholinergic receptors in the pyriform cortex and amygdala
    • McGeer, P. L.: McGeer, E. G.; Nagai, T.; Wong, P. T. A possible relationship between folic acid neurotoxicity and cholinergic receptors in the pyriform cortex and amygdala. J. Neural Transm. Suppl. 18:327-344: 1983.
    • (1983) J. Neural Transm. Suppl. , vol.18 , pp. 327-344
    • McGeer, P.L.1    McGeer, E.G.2    Nagai, T.3    Wong, P.T.4
  • 27
    • 33847474398 scopus 로고
    • Learning and memory dysfunction as selective neurotoxic effects
    • Tilson, H. A.; Sparber. S. B., eds. New York: John Wiley and Sons
    • Messing, R. B. Learning and memory dysfunction as selective neurotoxic effects. In: Tilson, H. A.; Sparber. S. B., eds. Neurotoxicants and neurobiological function: Effects of organoheavy metals. New York: John Wiley and Sons; 1987:279-302.
    • (1987) Neurotoxicants and Neurobiological Function: Effects of Organoheavy Metals , pp. 279-302
    • Messing, R.B.1
  • 28
    • 0024801149 scopus 로고
    • D-cycloserine. a positive modulator of the /V-methyl-D-aspartate receptor enhances performance oflearning tasks in rats
    • Monahan. J. B.; Handelmann. G. E.: Hood, W. F.: Cordi. A. A. D-cycloserine. a positive modulator of the /V-methyl-D-aspartate receptor enhances performance oflearning tasks in rats. Pharmacol. Biochem. Behav. 34:649-653; 1989.
    • (1989) Pharmacol. Biochem. Behav. , vol.34 , pp. 649-653
    • Monahan, J.B.1    Handelmann, G.E.2    Hood, W.F.3    Cordi, A.A.4
  • 29
    • 0022650213 scopus 로고
    • Selective impairment of learning and blockage of long-term potentiation by an A'-methyl-D-aspartate receptor antagonist. AP5
    • Morris, R. G. M.; Anderson, E.; Lynch, G. S.: Baudry. M. Selective impairment of learning and blockage of long-term potentiation by an A'-methyl-D-aspartate receptor antagonist. AP5. Nature 319:774; 1986.
    • (1986) Nature , vol.319 , pp. 774
    • Morris, R.G.M.1    Anderson, E.2    Lynch, G.S.3    Baudry, M.4
  • 30
    • 0027034531 scopus 로고
    • Neural and behavioural effects of domoic acid, an amnesic shellfish toxin, in the rat
    • Nakajima. S.: Potvin. J. L. Neural and behavioural effects of domoic acid, an amnesic shellfish toxin, in the rat. Can. J. Psychol. 46:569-581: 1992.
    • (1992) Can. J. Psychol. , vol.46 , pp. 569-581
    • Nakajima, S.1    Potvin, J.L.2
  • 31
    • 33847466852 scopus 로고
    • Unconditioned behavioral measures of neurotoxicity
    • Tilson. H. A.; Sparber, S. B., eds. New York: John Wiley and Sons
    • Norton, S. Unconditioned behavioral measures of neurotoxicity. In: Tilson. H. A.; Sparber, S. B., eds. Neurotoxicants and neurobiological function: Effects of organoheavy metals. New York: John Wiley and Sons; 1987:231-259.
    • (1987) Neurotoxicants and Neurobiological Function: Effects of Organoheavy Metals , pp. 231-259
    • Norton, S.1
  • 32
    • 0028181030 scopus 로고
    • Neuroexcitatory and neurotoxic actions of the amnesic shellfish poison, domoic acid
    • Peng. Y. G.; Taylor. T. B.: Finch, R. E.; Switzer. R. C.; Ramsdell. J. S. Neuroexcitatory and neurotoxic actions of the amnesic shellfish poison, domoic acid. Neuroreport 5:981-985; 1994.
    • (1994) Neuroreport , vol.5 , pp. 981-985
    • Peng, Y.G.1    Taylor, T.B.2    Finch, R.E.3    Switzer, R.C.4    Ramsdell, J.S.5
  • 34
    • 0025366777 scopus 로고
    • An outbreak of toxic encephalopathy caused by eating mussels contaminated with domoic acid
    • Perl. T. M.; Bedard. L.; Kosatsky. T.; Hockin. J. C.; Todd, E. C.; Remis. R. S. An outbreak of toxic encephalopathy caused by eating mussels contaminated with domoic acid. N. Engl. J. Med. 322:1775-1780: 1990.
    • (1990) N. Engl. J. Med. , vol.322 , pp. 1775-1780
    • Perl, T.M.1    Bedard, L.2    Kosatsky, T.3    Hockin, J.C.4    Todd, E.C.5    Remis, R.S.6
  • 37
    • 0026768638 scopus 로고
    • Patterns of Fos expression suggest similar mechanisms of action for the excitotoxins domoic and kainic acid
    • Robertson, H.; Renton, K.; Kohn, J.; White, T. Patterns of Fos expression suggest similar mechanisms of action for the excitotoxins domoic and kainic acid. Ann. NY Acad. Sei. 648:330-334; 1992.
    • (1992) Ann. NY Acad. Sei. , vol.648 , pp. 330-334
    • Robertson, H.1    Renton, K.2    Kohn, J.3    White, T.4
  • 38
    • 0002105713 scopus 로고
    • Quantitative morphometry for neurotoxicity assessment
    • Chang, L. W.; Slikker, W., Jr.. eds. New York: Academic Press
    • Scallet, A. C. Quantitative morphometry for neurotoxicity assessment. In: Chang, L. W.; Slikker, W., Jr.. eds. Neurotoxicology: Approaches and methods. New York: Academic Press; 1995:99-129.
    • (1995) Neurotoxicology: Approaches and Methods , pp. 99-129
    • Scallet, A.C.1
  • 40
    • 0023701279 scopus 로고
    • Neuropathological evaluation by combined immunohistochemistry and degeneration-specific methods: Application to methylenedioxymethamphetamine
    • Scallet, A. C.: Lipe, G. W.; Ali, S. F.; Holson, R. R.; Frith, C. H.; Slikker, W., Jr. Neuropathological evaluation by combined immunohistochemistry and degeneration-specific methods: Application to methylenedioxymethamphetamine. Neurotoxicology 9:529-538; 1988.
    • (1988) Neurotoxicology , vol.9 , pp. 529-538
    • Scallet, A.C.1    Lipe, G.W.2    Ali, S.F.3    Holson, R.R.4    Frith, C.H.5    Slikker Jr., W.6
  • 43
    • 33646284082 scopus 로고
    • Neurobehavioral assessment following low dose exposure to domoic acid (DOMA) in the rodent
    • Abstract #554.16
    • Sobotka, T. J.; Brodie, R.; Quander, D. Y.; Hall, S.; Bryant, M.; Barton, C. N. Neurobehavioral assessment following low dose exposure to domoic acid (DOMA) in the rodent. Soc. Neurosci. Abstr. 19:1347 (Abstract #554.16); 1993.
    • (1993) Soc. Neurosci. Abstr. , vol.19 , pp. 1347
    • Sobotka, T.J.1    Brodie, R.2    Quander, D.Y.3    Hall, S.4    Bryant, M.5    Barton, C.N.6
  • 44
    • 0026354443 scopus 로고
    • NMDA receptor channel antagonism by dizocilpine (MK-801) impairs performance of rats in aversively motivated complex maze tasks
    • Spangler, E. L.: Breshnahan, E. L.; Garofalo, P.: Muth, N. J.; Heller, B.; Ingram, D. K. NMDA receptor channel antagonism by dizocilpine (MK-801) impairs performance of rats in aversively motivated complex maze tasks. Pharmacol. Biochem. Behav. 40:949-958; 1991.
    • (1991) Pharmacol. Biochem. Behav. , vol.40 , pp. 949-958
    • Spangler, E.L.1    Breshnahan, E.L.2    Garofalo, P.3    Muth, N.J.4    Heller, B.5    Ingram, D.K.6
  • 45
    • 0025007340 scopus 로고
    • Domoic acid: A dementia-inducing excitotoxic food poison with kainic acid receptor specificity
    • Stewart, G. R.: Zorumski, C. F.; Price. M. T.; Olney, J. W. Domoic acid: A dementia-inducing excitotoxic food poison with kainic acid receptor specificity. Exp. Neurol. 110:127-138; 1990.
    • (1990) Exp. Neurol. , vol.110 , pp. 127-138
    • Stewart, G.R.1    Zorumski, C.F.2    Price, M.T.3    Olney, J.W.4
  • 46
    • 0025830422 scopus 로고
    • Hippocampal damage produced by systemic injections of domoic acid in mice
    • Strain, S. M.; Tasker, R. A. Hippocampal damage produced by systemic injections of domoic acid in mice. Neuroscience 44:343352;1991.
    • (1991) Neuroscience , vol.44 , pp. 343352
    • Strain, S.M.1    Tasker, R.A.2
  • 48
    • 0025676181 scopus 로고
    • Domoic acid, an environmental toxin, produces hippocampal damage and severe memory impairment
    • Sutherland, R. J.: Hoesing, J. M.; Whishaw, I. Q. Domoic acid, an environmental toxin, produces hippocampal damage and severe memory impairment. Neurosci. Lett. 120:221-223; 1990.
    • (1990) Neurosci. Lett. , vol.120 , pp. 221-223
    • Sutherland, R.J.1    Hoesing, J.M.2    Whishaw, I.Q.3
  • 49
    • 0023944453 scopus 로고
    • Both competitive and noncompetitive antagonists of jV-methyl-D-aspartic acid disrupt brightness discrimination in rats
    • Tang, A. H.; Ho, P. M. Both competitive and noncompetitive antagonists of jV-methyl-D-aspartic acid disrupt brightness discrimination in rats. Eur. J. Pharmacol. 151:143-146; 1988.
    • (1988) Eur. J. Pharmacol. , vol.151 , pp. 143-146
    • Tang, A.H.1    Ho, P.M.2
  • 52
    • 0025762957 scopus 로고
    • Domoic acid enhances the K( + )-evoked release of endogenous glutamate from guinea pig hippocampal mossy fiber synaptosomes
    • Terrian, D. M.: Conner-Kerr. T. A.; Privette. T. H.: Gannon, R. L. Domoic acid enhances the K( + )-evoked release of endogenous glutamate from guinea pig hippocampal mossy fiber synaptosomes. Brain Res. 551:303-307; 1991.
    • (1991) Brain Res. , vol.551 , pp. 303-307
    • Terrian, D.M.1    Conner-Kerr, T.A.2    Privette, T.H.3    Gannon, R.L.4
  • 53
    • 0023546527 scopus 로고
    • Behavioral indices of neurotoxicity: What can be measured?
    • Tilson, H. A. Behavioral indices of neurotoxicity: What can be measured? Neurotoxicol. Teratol. 9:427-443; 1987.
    • (1987) Neurotoxicol. Teratol. , vol.9 , pp. 427-443
    • Tilson, H.A.1
  • 54
    • 0011316359 scopus 로고
    • Bases of excitatory amino acid system-related neurotoxicity
    • Chang, L. W.; Slikker, W., Jr.. eds. New York: Academic Press
    • Tilson, H. A.; Mundy, W. R. Bases of excitatory amino acid system-related neurotoxicity. In: Chang, L. W.; Slikker, W., Jr.. eds. Neurotoxicology: Approaches and methods. New York: Academic Press; 1995:359-370.
    • (1995) Neurotoxicology: Approaches and Methods , pp. 359-370
    • Tilson, H.A.1    Mundy, W.R.2
  • 55
    • 0028416935 scopus 로고
    • Serum domoic acid clearance and clinical observations in the cynomolgus monkey and Sprague-Dawley rat following a single IV dose
    • Truelove, J.: Iverson. F. Serum domoic acid clearance and clinical observations in the cynomolgus monkey and Sprague-Dawley rat following a single IV dose. Bull. Environ. Contam. Toxicol. 52:479-486: 1994.
    • (1994) Bull. Environ. Contam. Toxicol. , vol.52 , pp. 479-486
    • Truelove, J.1    Iverson, F.2
  • 56
    • 0012744992 scopus 로고
    • Neuropathology of experimental domoic acid poisoning in nonhuman primates and rats
    • Tryphonas. L.; Truelove. J.; Iverson, F.; Todd, E. C.; Nera, E. A. Neuropathology of experimental domoic acid poisoning in nonhuman primates and rats. Can. Dis. Wkly. Rep. 16(Suppl. 1E):7581; 1990.
    • (1990) Can. Dis. Wkly. Rep. , vol.16 , Issue.SUPPL. 1E , pp. 7581
    • Tryphonas, L.1    Truelove, J.2    Iverson, F.3    Todd, E.C.4    Nera, E.A.5
  • 57
    • 0025630177 scopus 로고
    • Experimental oral toxicity of domoic acid in cynomolgus monkeys (Macaca fasacularis) and rats
    • Tryphonas. L.; Truelove, J.: Todd. E.; Nera, E.; Iverson, F. Experimental oral toxicity of domoic acid in cynomolgus monkeys (Macaca fasacularis) and rats. Food Chem. Toxicol. 28:707715; 1990.
    • (1990) Food Chem. Toxicol. , vol.28 , pp. 707715
    • Tryphonas, L.1    Truelove, J.2    Todd, E.3    Nera, E.4    Iverson, F.5
  • 58
    • 0025161217 scopus 로고
    • Acute parenteral neurotoxicity of domoic acid in cynomolgus monkeys
    • Tryphonas, L.; Truelove, J.; Iverson, F. Acute parenteral neurotoxicity of domoic acid in cynomolgus monkeys. Toxicol. Pathol. 18:297-303: 1990.
    • (1990) Toxicol. Pathol. , vol.18 , pp. 297-303
    • Tryphonas, L.1    Truelove, J.2    Iverson, F.3
  • 60
    • 0342954807 scopus 로고
    • Memory loss following domoic acid intoxication from ingestion of toxic mussels
    • Zatorre, R. J. Memory loss following domoic acid intoxication from ingestion of toxic mussels. Can. Dis. Wkly. Rep. 16(Suppl. 1E):103-104; 1990.
    • (1990) Can. Dis. Wkly. Rep. , vol.16 , Issue.SUPPL. 1E , pp. 103-104
    • Zatorre, R.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.