Arf and p53 act as guardians of a quiescent cellular state by protecting against immortalization of cells with stable genomes

Biochemical and Biophysical Research Communications

Volumn 432, Issue 1, 2013, Pages 34-39

  Osawa, Tomoyuki ^a,b   Atsumi, Yuko ^a,c   Sugihara, Eiji ^d   Saya, Hideyuki ^d   Kanno, Masamoto ^e   Tashiro, Fumio ^b   Masutani, Mitsuko ^a   Yoshioka, Ken ichi ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

^c KITASATO UNIVERSITY   (Japan)

^d KEIO UNIVERSITY   (Japan)

^e HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Arf; Genome stability; H2AX; P53; Quiescent state

Indexed keywords

ARF PROTEIN; HISTONE H2AX; PROTEIN P53;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL IMMORTALIZATION; CONTROLLED STUDY; DOWN REGULATION; GENE INDUCTION; GENOMIC INSTABILITY; IMMUNOBLOTTING; MOUSE; NONHUMAN; PRIORITY JOURNAL; TETRAPLOIDY; WILD TYPE;

3T3 CELLS; ANIMALS; CELL CYCLE CHECKPOINTS; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DIPLOIDY; GENOMIC INSTABILITY; HISTONES; MICE; MICE, KNOCKOUT; MITOSIS; TETRAPLOIDY; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84875372142     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.01.091     Document Type: Article

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