Delivery of definable number of drug or growth factor loaded poly(dl-lactic acid-co-glycolic acid) microparticles within human embryonic stem cell derived aggregates

Journal of Controlled Release

Volumn 168, Issue 1, 2013, Pages 18-27

  Qutachi, Omar ^a   Shakesheff, Kevin M ^a   Buttery, Lee D K ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Drug delivery; Microparticles; Osteogenesis; PDLLGA; Simvastatin; Stem cells

Indexed keywords

ENDOTHELIAL DIFFERENTIATION; HISTOCHEMICAL STAININGS; HUMAN EMBRYONIC STEM CELLS; MICRO-PARTICLES; OSTEOGENESIS; OSTEOGENIC DIFFERENTIATION; SIMVASTATIN; SINGLE-CELL SUSPENSIONS;

CELL CULTURE; CELL GROWTH; CENTRIFUGATION; DRUG DELIVERY; LACTIC ACID; MONOLAYERS; STEM CELLS; THREE DIMENSIONAL COMPUTER GRAPHICS; TISSUE ENGINEERING;

AGGREGATES;

ALIZARIN RED S; CALCIUM; COLLAGEN TYPE 1; OSTEOCALCIN; POLYGLACTIN; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; SIMVASTATIN; TRANSCRIPTION FACTOR RUNX2;

ARTICLE; CELL AGGREGATION; CELL CULTURE; CELL DIFFERENTIATION; CELL ENGINEERING; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; EMBRYOID BODY; EMBRYONIC STEM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HISTOCHEMISTRY; HUMAN; HUMAN CELL; HYDROPHOBICITY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; NANOFABRICATION; OSTEOBLAST; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY;

BONE MORPHOGENETIC PROTEIN 2; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DRUG CARRIERS; EMBRYONIC STEM CELLS; HUMANS; LACTIC ACID; OSTEOCALCIN; POLYGLYCOLIC ACID; SIMVASTATIN; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84875304095     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.02.029     Document Type: Article

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