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Volumn 3, Issue 5, 2009, Pages 398-404

Signalling strategies for osteogenic differentiation of human umbilical cord mesenchymal stromal cells for 3D bone tissue engineering

Author keywords

IGF 1; Osteogenesis; Stem cells; Umbilical cord stroma

Indexed keywords

BONE; CALCIUM; CELL ENGINEERING; CELL PROLIFERATION; CELL SIGNALING; GENE EXPRESSION; LACTIC ACID; SCAFFOLDS (BIOLOGY);

EID: 70449469349     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.176     Document Type: Article
Times cited : (63)

References (48)
  • 1
    • 0038372525 scopus 로고    scopus 로고
    • Proliferation and differentiation of osteoblasts and adipocytes in rat bone marrow stromal cell cultures: Effects of dexamethasone and calcitriol
    • Atmani H, Chappard D, Basle MF. 2003; Proliferation and differentiation of osteoblasts and adipocytes in rat bone marrow stromal cell cultures: effects of dexamethasone and calcitriol. J Cell Biochem 89: 364-372.
    • (2003) J Cell Biochem , vol.89 , pp. 364-372
    • Atmani, H.1    Chappard, D.2    Basle, M.F.3
  • 2
    • 34547122719 scopus 로고    scopus 로고
    • Comparison of proliferative and multilineage differentiation potential of humanmesenchymal stem cells derived from umbilical cord and bone marrow
    • Baksh D, Yao R, Tuan RS. 2007; Comparison of proliferative and multilineage differentiation potential of humanmesenchymal stem cells derived from umbilical cord and bone marrow. Stem Cells 25: 1384-1392.
    • (2007) Stem Cells , vol.25 , pp. 1384-1392
    • Baksh, D.1    Yao, R.2    Tuan, R.S.3
  • 3
    • 0028534864 scopus 로고
    • The effects of dexamethasone and 1,25-dihydroxyvitamin D3 on osteogenic differentiation of human marrow stromal cells in vitro
    • Beresford JN, Joyner CJ, Devlin C, Triffitt JT. 1994; The effects of dexamethasone and 1,25-dihydroxyvitamin D3 on osteogenic differentiation of human marrow stromal cells in vitro. Arch Oral Biol 39: 941-947.
    • (1994) Arch Oral Biol , vol.39 , pp. 941-947
    • Beresford, J.N.1    Joyner, C.J.2    Devlin, C.3    Triffitt, J.T.4
  • 4
    • 39749171878 scopus 로고    scopus 로고
    • Native umbilical cord matrix stem cells express hepatic markers and differentiate into hepatocyte-like cells
    • Campard D, Lysy PA, Najimi M, Sokal EM. 2008; Native umbilical cord matrix stem cells express hepatic markers and differentiate into hepatocyte-like cells. Gastroenterology 134: 833-848.
    • (2008) Gastroenterology , vol.134 , pp. 833-848
    • Campard, D.1    Lysy, P.A.2    Najimi, M.3    Sokal, E.M.4
  • 5
    • 0030611005 scopus 로고    scopus 로고
    • Vitamin D3 analogs and their 24-oxo metabolites equally inhibit clonal proliferation of a variety of cancer cells but have differing molecular effects
    • Campbell MJ, Reddy GS, Koeffler HP. 1997; Vitamin D3 analogs and their 24-oxo metabolites equally inhibit clonal proliferation of a variety of cancer cells but have differing molecular effects. J Cell Biochem 66: 413-425.
    • (1997) J Cell Biochem , vol.66 , pp. 413-425
    • Campbell, M.J.1    Reddy, G.S.2    Koeffler, H.P.3
  • 6
    • 36249001191 scopus 로고    scopus 로고
    • Concise review: Human umbilical cord stroma with regard to the source of fetus-derived stem cells
    • Can A, Karahuseyinoglu S. 2007; Concise review: human umbilical cord stroma with regard to the source of fetus-derived stem cells. Stem Cells 25: 2886-2895.
    • (2007) Stem Cells , vol.25 , pp. 2886-2895
    • Can, A.1    Karahuseyinoglu, S.2
  • 7
    • 2942700189 scopus 로고    scopus 로고
    • Inhibition of growth and differentiation of osteoprogenitors in mouse bone marrow stromal cell cultures by increased donor age and glucocorticoid treatment
    • Chen TL. 2004; Inhibition of growth and differentiation of osteoprogenitors in mouse bone marrow stromal cell cultures by increased donor age and glucocorticoid treatment. Bone 35: 83-95.
    • (2004) Bone , vol.35 , pp. 83-95
    • Chen, T.L.1
  • 8
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
    • Ducy P, Zhang R, Geoffroy V, et al. 1997; Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 89: 747-754.
    • (1997) Cell , vol.89 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3
  • 9
    • 33645532494 scopus 로고    scopus 로고
    • Conversion of human umbilical cord mesenchymal stem cells in Wharton's jelly to dopaminergic neurons in vitro: Potential therapeutic application for Parkinsonism
    • Fu YS, Cheng YC, Lin MY, et al. 2006; Conversion of human umbilical cord mesenchymal stem cells in Wharton's jelly to dopaminergic neurons in vitro: potential therapeutic application for Parkinsonism. Stem Cells 24: 115-124.
    • (2006) Stem Cells , vol.24 , pp. 115-124
    • Fu, Y.S.1    Cheng, Y.C.2    Lin, M.Y.3
  • 10
    • 34748852625 scopus 로고    scopus 로고
    • Effects of demineralized bone matrix on proliferation and osteogenic differentiation of mesenchymal stem cells from human umbilical cord
    • Honsawek S, Dhitiseith D, Phupong V. 2006; Effects of demineralized bone matrix on proliferation and osteogenic differentiation of mesenchymal stem cells from human umbilical cord. J Med Assoc Thai 89(suppl 3): S189-195.
    • (2006) J Med Assoc Thai , vol.89 , Issue.SUPPL. 3
    • Honsawek, S.1    Dhitiseith, D.2    Phupong, V.3
  • 11
    • 0034771207 scopus 로고    scopus 로고
    • Polyglycolide: Degradation and drug release. Part I: changes inmorphology during degradation
    • Hurrell S, Cameron RE. 2001; Polyglycolide: degradation and drug release. Part I: changes inmorphology during degradation. JMater Sci Mater Med 12: 811-816.
    • (2001) JMater Sci Mater Med , vol.12 , pp. 811-816
    • Hurrell, S.1    Cameron, R.E.2
  • 12
    • 0031012411 scopus 로고    scopus 로고
    • Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro
    • Jaiswal N, Haynesworth SE, Caplan AI, Bruder SP. 1997; Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro. J Cell Biochem 64: 295-312.
    • (1997) J Cell Biochem , vol.64 , pp. 295-312
    • Jaiswal, N.1    Haynesworth, S.E.2    Caplan, A.I.3    Bruder, S.P.4
  • 13
    • 50149107947 scopus 로고    scopus 로고
    • Growth factors reduce the suppression of proliferation and osteogenic differentiation by titanium particles on MSCs
    • Jeong WK, Park SW, Im GI. 2008; Growth factors reduce the suppression of proliferation and osteogenic differentiation by titanium particles on MSCs. J Biomed Mater Res A 86A: 1137-1144.
    • (2008) J Biomed Mater Res A , vol.86 A , pp. 1137-1144
    • Jeong, W.K.1    Park, S.W.2    Im, G.I.3
  • 14
    • 33845983227 scopus 로고    scopus 로고
    • Potential treatment of cerebral global ischemia with Oct-4+ umbilical cord matrix cells
    • Jomura S, Uy M, Mitchell K, et al. 2007; Potential treatment of cerebral global ischemia with Oct-4+ umbilical cord matrix cells. Stem Cells 25: 98-106.
    • (2007) Stem Cells , vol.25 , pp. 98-106
    • Jomura, S.1    Uy, M.2    Mitchell, K.3
  • 15
    • 33846923121 scopus 로고    scopus 로고
    • Biology of stem cells in human umbilical cord stroma: In situ and in vitro surveys
    • Karahuseyinoglu S, Cinar O, Kilic E, et al. 2007; Biology of stem cells in human umbilical cord stroma: in situ and in vitro surveys. Stem Cells 25: 319-331.
    • (2007) Stem Cells , vol.25 , pp. 319-331
    • Karahuseyinoglu, S.1    Cinar, O.2    Kilic, E.3
  • 16
    • 3242877269 scopus 로고    scopus 로고
    • The anabolic effects of GH/IGF system on bone
    • Kasukawa Y, Miyakoshi N, Mohan S. 2004; The anabolic effects of GH/IGF system on bone. Curr Pharm Des 10: 2577-2592.
    • (2004) Curr Pharm Des , vol.10 , pp. 2577-2592
    • Kasukawa, Y.1    Miyakoshi, N.2    Mohan, S.3
  • 17
    • 33746715059 scopus 로고    scopus 로고
    • Glucocorticoids suppress bone formation via the osteoclast
    • Kim HJ, Zhao H, Kitaura H, et al. 2006; Glucocorticoids suppress bone formation via the osteoclast. J Clin Invest 116: 2152-2160.
    • (2006) J Clin Invest , vol.116 , pp. 2152-2160
    • Kim, H.J.1    Zhao, H.2    Kitaura, H.3
  • 18
    • 32044467131 scopus 로고    scopus 로고
    • Insulin-like growth factor-I induces early osteoblast gene expression in human mesenchymal stem cells
    • Koch H, Jadlowiec JA, Campbell PG. 2005; Insulin-like growth factor-I induces early osteoblast gene expression in human mesenchymal stem cells. Stem Cells Dev 14: 621-631.
    • (2005) Stem Cells Dev , vol.14 , pp. 621-631
    • Koch, H.1    Jadlowiec, J.A.2    Campbell, P.G.3
  • 19
    • 0030684749 scopus 로고    scopus 로고
    • Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
    • Komori T, Yagi H, Nomura S, et al. 1997; Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89: 755-764.
    • (1997) Cell , vol.89 , pp. 755-764
    • Komori, T.1    Yagi, H.2    Nomura, S.3
  • 20
    • 0033128054 scopus 로고    scopus 로고
    • An overview of vertebrate mineralization with emphasis on collagen-mineral interaction
    • Landis WJ. 1999; An overview of vertebrate mineralization with emphasis on collagen-mineral interaction. Gravit Space Biol Bull 12: 15-26.
    • (1999) Gravit Space Biol Bull , vol.12 , pp. 15-26
    • Landis, W.J.1
  • 21
    • 33846602261 scopus 로고    scopus 로고
    • In vitro multipotentiality and characterization of human unfractured traumatic hemarthrosisderived progenitor cells: A potential cell source for tissue repair
    • Lee SY, Miwa M, Sakai Y, et al. 2007; In vitro multipotentiality and characterization of human unfractured traumatic hemarthrosisderived progenitor cells: a potential cell source for tissue repair. J Cell Physiol 210: 561-566.
    • (2007) J Cell Physiol , vol.210 , pp. 561-566
    • Lee, S.Y.1    Miwa, M.2    Sakai, Y.3
  • 22
    • 0030016220 scopus 로고    scopus 로고
    • Growth factors for bone growth and repair: IGF, TGFβ and BMP
    • S
    • Linkhart TA, Mohan S, Baylink DJ. 1996; Growth factors for bone growth and repair: IGF, TGFβ and BMP. Bone 19: S 1-12.
    • (1996) Bone , vol.19 , pp. 1-12
    • Linkhart, T.A.1    Mohan, S.2    Baylink, D.J.3
  • 23
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2[-ΔΔC(T)] method
    • Livak KJ, Schmittgen TD. 2001; Analysis of relative gene expression data using real-time quantitative PCR and the 2[-ΔΔC(T)] method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 24
    • 33847675933 scopus 로고    scopus 로고
    • Cells isolated from umbilical cord tissue rescue photoreceptors and visual functions in a rodent model of retinal disease
    • Lund RD, Wang S, Lu B, et al. 2007; Cells isolated from umbilical cord tissue rescue photoreceptors and visual functions in a rodent model of retinal disease. Stem Cells 25: 602-611.
    • (2007) Stem Cells , vol.25 , pp. 602-611
    • Lund, R.D.1    Wang, S.2    Lu, B.3
  • 25
    • 33746936122 scopus 로고    scopus 로고
    • Isolation and characterization of human umbilical cord mesenchymal stem cells with haematopoiesis-supportive function and other potentials
    • Lu LL, Liu YJ, Yang SG, et al. 2006; Isolation and characterization of human umbilical cord mesenchymal stem cells with haematopoiesis-supportive function and other potentials. Haematologica 91: 1017-1026.
    • (2006) Haematologica , vol.91 , pp. 1017-1026
    • Lu, L.L.1    Liu, Y.J.2    Yang, S.G.3
  • 26
    • 34249889868 scopus 로고    scopus 로고
    • Stem cells associated with macroporous bioceramics for long bone repair: 6- to 7-year outcome of a pilot clinical study
    • Marcacci M, Kon E,Moukhachev V, et al. 2007; Stem cells associated with macroporous bioceramics for long bone repair: 6- to 7-year outcome of a pilot clinical study. Tissue Eng 13: 947-955.
    • (2007) Tissue Eng , vol.13 , pp. 947-955
    • Marcacci, M.1    Kon, E.2    Moukhachev, V.3
  • 28
    • 2942588974 scopus 로고    scopus 로고
    • Bone tissue engineering using human mesenchymal stem cells: Effects of scaffold material and medium flow
    • Meinel L, Karageorgiou V, Fajardo R, et al. 2004; Bone tissue engineering using human mesenchymal stem cells: effects of scaffold material and medium flow. Ann Biomed Eng 32: 112-122.
    • (2004) Ann Biomed Eng , vol.32 , pp. 112-122
    • Meinel, L.1    Karageorgiou, V.2    Fajardo, R.3
  • 29
    • 0034895190 scopus 로고    scopus 로고
    • Age-related decline in the osteogenic potential of human bone marrow cells cultured in threedimensional collagen sponges
    • Mueller SM, Glowacki J. 2001; Age-related decline in the osteogenic potential of human bone marrow cells cultured in threedimensional collagen sponges. J Cell Biochem 82: 583-590.
    • (2001) J Cell Biochem , vol.82 , pp. 583-590
    • Mueller, S.M.1    Glowacki, J.2
  • 30
    • 16644373148 scopus 로고    scopus 로고
    • Dexamethasone induces human spinal ligament derived cells toward osteogenic differentiation
    • Murata H, Tanaka H, Taguchi T, et al. 2004; Dexamethasone induces human spinal ligament derived cells toward osteogenic differentiation. J Cell Biochem 92: 715-722.
    • (2004) J Cell Biochem , vol.92 , pp. 715-722
    • Murata, H.1    Tanaka, H.2    Taguchi, T.3
  • 31
    • 0019220057 scopus 로고
    • Receptors for 1,25(OH)2-vitamin D3 enriched in cloned osteoblast-like rat osteogenic sarcoma cells
    • Partridge NC, Frampton RJ, Eisman JA, et al. 1980; Receptors for 1,25(OH)2-vitamin D3 enriched in cloned osteoblast-like rat osteogenic sarcoma cells. FEBS Lett 115: 139-142.
    • (1980) FEBS Lett , vol.115 , pp. 139-142
    • Partridge, N.C.1    Frampton, R.J.2    Eisman, J.A.3
  • 32
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • Pittenger MF, Mackay AM, Beck SC, et al. 1999; Multilineage potential of adult human mesenchymal stem cells. Science 284: 143-147.
    • (1999) Science , vol.284 , pp. 143-147
    • Pittenger, M.F.1    Mackay, A.M.2    Beck, S.C.3
  • 33
    • 0035253558 scopus 로고    scopus 로고
    • Repair of large bone defects with the use of autologous bonemarrowstromal cells
    • Quarto R, Mastrogiacomo M, Cancedda R, et al. 2001; Repair of large bone defects with the use of autologous bonemarrowstromal cells. N Engl JMed 344: 385-386.
    • (2001) N Engl JMed , vol.344 , pp. 385-386
    • Quarto, R.1    Mastrogiacomo, M.2    Cancedda, R.3
  • 34
    • 0027717641 scopus 로고
    • The role of insulin, growth hormone and IGF-I as anabolic agents in the critically ill
    • Ross RJ, Rodriguez-Arnao J, Bentham J, Coakley JH. 1993; The role of insulin, growth hormone and IGF-I as anabolic agents in the critically ill. Intens Care Med 19(suppl 2): S54-57.
    • (1993) Intens Care Med , vol.19 , Issue.SUPPL. 2
    • Ross, R.J.1    Rodriguez-Arnao, J.2    Bentham, J.3    Coakley, J.H.4
  • 35
    • 13744254666 scopus 로고    scopus 로고
    • Human umbilical cord perivascular (HUCPV) cells: A source of mesenchymal progenitors
    • Sarugaser R, Lickorish D, Baksh D, et al. 2005; Human umbilical cord perivascular (HUCPV) cells: a source of mesenchymal progenitors. Stem Cells 23: 220-229.
    • (2005) Stem Cells , vol.23 , pp. 220-229
    • Sarugaser, R.1    Lickorish, D.2    Baksh, D.3
  • 36
    • 26844574658 scopus 로고    scopus 로고
    • Runx2: A master organizer of gene transcription in developing and maturing osteoblasts
    • Schroeder TM, Jensen ED, Westendorf JJ. 2005; Runx2: a master organizer of gene transcription in developing and maturing osteoblasts. Birth Defects Res C Embryol Today 75: 213-225.
    • (2005) Birth Defects Res C Embryol Today , vol.75 , pp. 213-225
    • Schroeder, T.M.1    Jensen, E.D.2    Westendorf, J.J.3
  • 37
    • 60549108910 scopus 로고    scopus 로고
    • Mesenchymal stem cell-seeded collagen matrices for bone repair: Effects of cyclic tensile strain, cell density, and media conditions on matrix contraction in vitro
    • Sumanasinghe RD, Osborne JA, Loboa EG. 2008; Mesenchymal stem cell-seeded collagen matrices for bone repair: effects of cyclic tensile strain, cell density, and media conditions on matrix contraction in vitro. J Biomed Mater Res A 88: 778-786.
    • (2008) J Biomed Mater Res A , vol.88 , pp. 778-786
    • Sumanasinghe, R.D.1    Osborne, J.A.2    Loboa, E.G.3
  • 38
    • 0036249887 scopus 로고    scopus 로고
    • In vitro osteogenic differentiation of rat bone marrow cells subcultured with and without dexamethasone
    • ter Brugge PJ, Jansen JA. 2002; In vitro osteogenic differentiation of rat bone marrow cells subcultured with and without dexamethasone. Tissue Eng 8: 321-331.
    • (2002) Tissue Eng , vol.8 , pp. 321-331
    • ter Brugge, P.J.1    Jansen, J.A.2
  • 39
    • 0142029486 scopus 로고    scopus 로고
    • Transcriptional regulation of the human Runx2/Cbfa1 gene promoter by bone morphogenetic protein-7
    • Tou L, Quibria N, Alexander JM. 2003; Transcriptional regulation of the human Runx2/Cbfa1 gene promoter by bone morphogenetic protein-7. Mol Cell Endocrinol 205: 121-129.
    • (2003) Mol Cell Endocrinol , vol.205 , pp. 121-129
    • Tou, L.1    Quibria, N.2    Alexander, J.M.3
  • 40
    • 43049151898 scopus 로고    scopus 로고
    • Wharton's jelly-derived cells are a primitive stromal cell population
    • Troyer DL, Weiss ML. 2008; Wharton's jelly-derived cells are a primitive stromal cell population. Stem Cells 26: 591-599.
    • (2008) Stem Cells , vol.26 , pp. 591-599
    • Troyer, D.L.1    Weiss, M.L.2
  • 41
    • 0035144210 scopus 로고    scopus 로고
    • High concentrations of dexamethasone suppress the proliferation but not the differentiation or further maturation of human osteoblast precursors in vitro: Relevance to glucocorticoid-induced osteoporosis
    • Walsh S, Jordan GR, Jefferiss C, et al. 2001; High concentrations of dexamethasone suppress the proliferation but not the differentiation or further maturation of human osteoblast precursors in vitro: relevance to glucocorticoid-induced osteoporosis. Rheumatology (Oxf) 40: 74-83.
    • (2001) Rheumatology (Oxf) , vol.40 , pp. 74-83
    • Walsh, S.1    Jordan, G.R.2    Jefferiss, C.3
  • 42
    • 10444248938 scopus 로고    scopus 로고
    • Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord
    • Wang HS, Hung SC, Peng ST, et al. 2004; Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord. Stem Cells 22: 1330-1337.
    • (2004) Stem Cells , vol.22 , pp. 1330-1337
    • Wang, H.S.1    Hung, S.C.2    Peng, S.T.3
  • 43
    • 60249083841 scopus 로고    scopus 로고
    • Hyaline cartilage cells outperform mandibular condylar cartilage cells in a TMJ fibrocartilage tissue engineering application
    • Wang L, Lazebnik M, Detamore MS. 2009; Hyaline cartilage cells outperform mandibular condylar cartilage cells in a TMJ fibrocartilage tissue engineering application. Osteoarthr Cartilage 17(3): 346-353.
    • (2009) Osteoarthr Cartilage , vol.17 , Issue.3 , pp. 346-353
    • Wang, L.1    Lazebnik, M.2    Detamore, M.S.3
  • 44
    • 67749135996 scopus 로고    scopus 로고
    • Effect of initial seeding density on human umbilical cord mesenchymal stromal cells for fibrocartilage tissue engineering
    • Epub ahead of print
    • Wang L, Seshareddy K, Weiss ML, Detamore MS. 2008; Effect of initial seeding density on human umbilical cord mesenchymal stromal cells for fibrocartilage tissue engineering. Tissue Eng A 1-9 [Epub ahead of print].
    • (2008) Tissue Eng A , pp. 1-9
    • Wang, L.1    Seshareddy, K.2    Weiss, M.L.3    Detamore, M.S.4
  • 45
    • 33846628657 scopus 로고    scopus 로고
    • Wu KH, Zhou B, Lu SH, et al. 2007; In vitro and in vivo differentiation of human umbilical cord derived stem cells into endothelial cells. J Cell Biochem 100: 608-616.1
    • Wu KH, Zhou B, Lu SH, et al. 2007; In vitro and in vivo differentiation of human umbilical cord derived stem cells into endothelial cells. J Cell Biochem 100: 608-616.1
  • 46
    • 0037400540 scopus 로고    scopus 로고
    • A biodegradable1 nanofiber scaffold by electrospinning and its potential for bone tissue engineering
    • Yoshimoto H, Shin YM, Terai H, Vacanti JP. 2003; A biodegradable1 nanofiber scaffold by electrospinning and its potential for bone tissue engineering. Biomaterials 24: 2077-2082.
    • (2003) Biomaterials , vol.24 , pp. 2077-2082
    • Yoshimoto, H.1    Shin, Y.M.2    Terai, H.3    Vacanti, J.P.4
  • 47
    • 0037150403 scopus 로고    scopus 로고
    • In vitro degradation of poly(Llactic acid) fibers in phosphate buffered saline
    • Yuan X, Arthur FTM, Yao K. 2002; In vitro degradation of poly(Llactic acid) fibers in phosphate buffered saline. J Appl Polym Sci 85: 936-943.
    • (2002) J Appl Polym Sci , vol.85 , pp. 936-943
    • Yuan, X.1    Arthur, F.T.M.2    Yao, K.3
  • 48
    • 60549114431 scopus 로고    scopus 로고
    • Superior osteogenic capacity for bone tissue engineering of fetal compared to perinatal and adult mesenchymal stem cells
    • Epub ahead of print
    • Zhang ZY, Teoh SH, Chong MS, et al. 2008; Superior osteogenic capacity for bone tissue engineering of fetal compared to perinatal and adult mesenchymal stem cells. Stem Cells 1-5 [Epub ahead of print].
    • (2008) Stem Cells , pp. 1-5
    • Zhang, Z.Y.1    Teoh, S.H.2    Chong, M.S.3


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