메뉴 건너뛰기




Volumn 296, Issue , 2013, Pages 13-24

The effect of overexpression of PGC-1α on the mtDNA4834 common deletion in a rat cochlear marginal cell senescence model

Author keywords

[No Author keywords available]

Indexed keywords

GALACTOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TRANSCRIPTION FACTOR NRF1;

EID: 84875259107     PISSN: 03785955     EISSN: 18785891     Source Type: Journal    
DOI: 10.1016/j.heares.2012.11.007     Document Type: Article
Times cited : (30)

References (59)
  • 1
    • 37249009271 scopus 로고    scopus 로고
    • Motif module map reveals enforcement of aging by continual NF-kappaB activity
    • Adler A.S., Sinha S., Kawahara T.L., Zhang J.Y., Segal E., Chang H.Y. Motif module map reveals enforcement of aging by continual NF-kappaB activity. Genes Dev. 2007, 21(24):3244-3257.
    • (2007) Genes Dev. , vol.21 , Issue.24 , pp. 3244-3257
    • Adler, A.S.1    Sinha, S.2    Kawahara, T.L.3    Zhang, J.Y.4    Segal, E.5    Chang, H.Y.6
  • 3
    • 0030849125 scopus 로고    scopus 로고
    • Mitochondrial DNA deletions associated with aging and possibly presbycusis: a human archival temporal bone study
    • Bai U., Seidman M.D., Hinojosa R., Quirk W.S. Mitochondrial DNA deletions associated with aging and possibly presbycusis: a human archival temporal bone study. Am. J. Otol. 1997, 18(4):449-453.
    • (1997) Am. J. Otol. , vol.18 , Issue.4 , pp. 449-453
    • Bai, U.1    Seidman, M.D.2    Hinojosa, R.3    Quirk, W.S.4
  • 4
    • 4544228457 scopus 로고    scopus 로고
    • Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology
    • Beinke S., Ley S.C. Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology. Biochem. J. 2004;Sep 1, 382(Pt 2):393-409.
    • (2004) Biochem. J. , vol.382 , Issue.PART 2 , pp. 393-409
    • Beinke, S.1    Ley, S.C.2
  • 5
    • 77952668415 scopus 로고    scopus 로고
    • Age-related hearing loss: is it a preventable condition?
    • Bielefeld E.C., Tanaka C., Chen G.D., Henderson D. Age-related hearing loss: is it a preventable condition?. Hear. Res. 2010, 264(1-2):98-107.
    • (2010) Hear. Res. , vol.264 , Issue.1-2 , pp. 98-107
    • Bielefeld, E.C.1    Tanaka, C.2    Chen, G.D.3    Henderson, D.4
  • 7
    • 33845744837 scopus 로고    scopus 로고
    • Initiation and beyond: multiple functions of the human mitochondrial transcription machinery
    • Bonawitz N.D., Clayton D.A., Shadel G.S. Initiation and beyond: multiple functions of the human mitochondrial transcription machinery. Mol. Cell. 2006, 24(6):813-825.
    • (2006) Mol. Cell. , vol.24 , Issue.6 , pp. 813-825
    • Bonawitz, N.D.1    Clayton, D.A.2    Shadel, G.S.3
  • 9
    • 77953913589 scopus 로고    scopus 로고
    • Age-related changes in the central auditory system: comparison of D-galactose-induced aging rats and naturally aging rats
    • Chen B., Zhong Y., Peng W., Sun Y., Kong W.J. Age-related changes in the central auditory system: comparison of D-galactose-induced aging rats and naturally aging rats. Brain Res. 2010, 1344:43-53.
    • (2010) Brain Res. , vol.1344 , pp. 43-53
    • Chen, B.1    Zhong, Y.2    Peng, W.3    Sun, Y.4    Kong, W.J.5
  • 10
    • 49649093187 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase 3 suppresses tumor angiogenesis in matrix metalloproteinase 2-down-regulated lung cancer
    • Chetty C., Lakka S.S., Bhoopathi P., Kunigal S., Geiss R., Rao J.S. Tissue inhibitor of metalloproteinase 3 suppresses tumor angiogenesis in matrix metalloproteinase 2-down-regulated lung cancer. Cancer Res. 2008;Jun 15, 68(12):4736-4745.
    • (2008) Cancer Res. , vol.68 , Issue.12 , pp. 4736-4745
    • Chetty, C.1    Lakka, S.S.2    Bhoopathi, P.3    Kunigal, S.4    Geiss, R.5    Rao, J.S.6
  • 11
    • 0037133730 scopus 로고    scopus 로고
    • Characterization of the 5'-flanking region of the rat gene for mitochondrial transcription factor A (Tfam)
    • Choi Y.S., Lee H.K., Pak Y.K. Characterization of the 5'-flanking region of the rat gene for mitochondrial transcription factor A (Tfam). Biochim. Biophys. Acta 2002, 1574(2):200-204.
    • (2002) Biochim. Biophys. Acta , vol.1574 , Issue.2 , pp. 200-204
    • Choi, Y.S.1    Lee, H.K.2    Pak, Y.K.3
  • 13
    • 0014031188 scopus 로고
    • Galactose conversion to D-xylulose: an alternate route of galactose metabolism
    • Cuatrecasas P., Segal S. Galactose conversion to D-xylulose: an alternate route of galactose metabolism. Science 1966, 153(3735):549-551.
    • (1966) Science , vol.153 , Issue.3735 , pp. 549-551
    • Cuatrecasas, P.1    Segal, S.2
  • 15
    • 84861190708 scopus 로고    scopus 로고
    • A long-term high-fat diet increases oxidative stress, mitochondrial damage and apoptosis in the inner ear of D-galactose-induced aging rats
    • Du Z., Yang Y., Hu Y., Sun Y., Zhang S., Peng W., Zhong Y., Huang X., Kong W. A long-term high-fat diet increases oxidative stress, mitochondrial damage and apoptosis in the inner ear of D-galactose-induced aging rats. Hear. Res. 2012 May, 287(1-2):15-24.
    • (2012) Hear. Res. , vol.287 , Issue.1-2 , pp. 15-24
    • Du, Z.1    Yang, Y.2    Hu, Y.3    Sun, Y.4    Zhang, S.5    Peng, W.6    Zhong, Y.7    Huang, X.8    Kong, W.9
  • 16
    • 0017076966 scopus 로고
    • Ageing changes in mammalian skeletal muscle: biochemical studies
    • Ermini M. Ageing changes in mammalian skeletal muscle: biochemical studies. Gerontology 1976, 22(4):301-316.
    • (1976) Gerontology , vol.22 , Issue.4 , pp. 301-316
    • Ermini, M.1
  • 17
    • 33644660537 scopus 로고    scopus 로고
    • PGC-1 coactivators: inducible regulators of energy metabolism in health and disease
    • Finck B.N., Kelly D.P. PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. J. Clin. Invest. 2006, 116(3):615-622.
    • (2006) J. Clin. Invest. , vol.116 , Issue.3 , pp. 615-622
    • Finck, B.N.1    Kelly, D.P.2
  • 19
    • 0029051835 scopus 로고
    • Structure, expression, and chromosomal assignment of the human gene encoding nuclear respiratory factor 1
    • Gopalakrishnan L., Scarpulla R.C. Structure, expression, and chromosomal assignment of the human gene encoding nuclear respiratory factor 1. J. Biol. Chem. 1995, 270(30):18019-18025.
    • (1995) J. Biol. Chem. , vol.270 , Issue.30 , pp. 18019-18025
    • Gopalakrishnan, L.1    Scarpulla, R.C.2
  • 20
    • 33845596500 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism
    • Handschin C., Spiegelman B.M. Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism. Endocr. Rev. 2006, 27(7):728-735.
    • (2006) Endocr. Rev. , vol.27 , Issue.7 , pp. 728-735
    • Handschin, C.1    Spiegelman, B.M.2
  • 21
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick L., Moorhead P.S. The serial cultivation of human diploid cell strains. Exp. Cell. Res. 1961, 37:585-621.
    • (1961) Exp. Cell. Res. , vol.37 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 22
    • 34548799705 scopus 로고    scopus 로고
    • Methods to detect biomarkers of cellular senescence: the senescence-associated beta-galactosidase assay
    • Itahana K., Campisi J., Dimri G.P. Methods to detect biomarkers of cellular senescence: the senescence-associated beta-galactosidase assay. Methods Mol. Biol. 2007, 371:21-31.
    • (2007) Methods Mol. Biol. , vol.371 , pp. 21-31
    • Itahana, K.1    Campisi, J.2    Dimri, G.P.3
  • 23
    • 45449084795 scopus 로고    scopus 로고
    • Cellular senescence and organismal aging
    • Jeyapalan J.C., Sedivy J.M. Cellular senescence and organismal aging. Mech. Ageing Dev. 2008, 129(7-8):467-474.
    • (2008) Mech. Ageing Dev. , vol.129 , Issue.7-8 , pp. 467-474
    • Jeyapalan, J.C.1    Sedivy, J.M.2
  • 24
    • 1542373685 scopus 로고    scopus 로고
    • Transcriptional regulatory circuits controlling mitochondrial biogenesis and function
    • Kelly D.P., Scarpulla R.C. Transcriptional regulatory circuits controlling mitochondrial biogenesis and function. Genes Dev. 2004, 18(4):357-368.
    • (2004) Genes Dev. , vol.18 , Issue.4 , pp. 357-368
    • Kelly, D.P.1    Scarpulla, R.C.2
  • 25
    • 0029905041 scopus 로고    scopus 로고
    • Establishment of primary cell culture from stria vascularis explants. Morphological and functional characterization
    • Kim H.N., Chang M.S., Chung M.H., Park K. Establishment of primary cell culture from stria vascularis explants. Morphological and functional characterization. Acta Otolaryngol. 1996, 116(6):805-811.
    • (1996) Acta Otolaryngol. , vol.116 , Issue.6 , pp. 805-811
    • Kim, H.N.1    Chang, M.S.2    Chung, M.H.3    Park, K.4
  • 26
  • 28
    • 33745009756 scopus 로고    scopus 로고
    • The relation between D-galactose injection and mitochondrial DNA 4834 bp deletion mutation
    • Kong W.J., Wang Y., Wang Q., Hu Y.J., Han Y.C., Liu J. The relation between D-galactose injection and mitochondrial DNA 4834 bp deletion mutation. Exp. Gerontol. 2006, 41(6):628-634.
    • (2006) Exp. Gerontol. , vol.41 , Issue.6 , pp. 628-634
    • Kong, W.J.1    Wang, Y.2    Wang, Q.3    Hu, Y.J.4    Han, Y.C.5    Liu, J.6
  • 29
    • 24144463983 scopus 로고    scopus 로고
    • Metabolic control through the PGC-1 family of transcription coactivators
    • Lin J., Handschin C., Spiegelman B.M. Metabolic control through the PGC-1 family of transcription coactivators. Cell. Metab. 2005, 1(6):361-370.
    • (2005) Cell. Metab. , vol.1 , Issue.6 , pp. 361-370
    • Lin, J.1    Handschin, C.2    Spiegelman, B.M.3
  • 30
    • 0025773073 scopus 로고
    • Primary culture of vital marginal cells from cochlear explants of the stria vascularis
    • Melichar I., Gitter A.H. Primary culture of vital marginal cells from cochlear explants of the stria vascularis. Eur. Arch. Otorhinolaryngol. 1991, 248(6):358-365.
    • (1991) Eur. Arch. Otorhinolaryngol. , vol.248 , Issue.6 , pp. 358-365
    • Melichar, I.1    Gitter, A.H.2
  • 31
    • 0026707283 scopus 로고
    • Characterization of marginal and Claudius' cells growing from cochlear explants in vitro
    • Melichar I., Gitter A.H., Dartsch P.C., Zenner H.P. Characterization of marginal and Claudius' cells growing from cochlear explants in vitro. Hear. Res. 1992, 62(1):89-98.
    • (1992) Hear. Res. , vol.62 , Issue.1 , pp. 89-98
    • Melichar, I.1    Gitter, A.H.2    Dartsch, P.C.3    Zenner, H.P.4
  • 32
    • 78650009028 scopus 로고    scopus 로고
    • Upregulation of human selenoprotein H in murine hippocampal neuronal cells promotes mitochondrial biogenesis and functional performance
    • Mendelev N., Mehta S.L., Witherspoon S., He Q., Sexton J.Z., Li P.A. Upregulation of human selenoprotein H in murine hippocampal neuronal cells promotes mitochondrial biogenesis and functional performance. Mitochondrion 2011, 11(1):76-82.
    • (2011) Mitochondrion , vol.11 , Issue.1 , pp. 76-82
    • Mendelev, N.1    Mehta, S.L.2    Witherspoon, S.3    He, Q.4    Sexton, J.Z.5    Li, P.A.6
  • 33
    • 7444263525 scopus 로고    scopus 로고
    • Development of a quantitative PCR (TaqMan) assay for relative mitochondrial DNA copy number and the common mitochondrial DNA deletion in the rat
    • Nicklas J.A., Brooks E.M., Hunter T.C., Single R., Branda R.F. Development of a quantitative PCR (TaqMan) assay for relative mitochondrial DNA copy number and the common mitochondrial DNA deletion in the rat. Environ. Mol. Mutagen. 2004, 44(4):313-320.
    • (2004) Environ. Mol. Mutagen. , vol.44 , Issue.4 , pp. 313-320
    • Nicklas, J.A.1    Brooks, E.M.2    Hunter, T.C.3    Single, R.4    Branda, R.F.5
  • 34
    • 33748742725 scopus 로고    scopus 로고
    • Inhibition of hepatocyte nuclear factor 4 transcriptional activity by the nuclear factor kappaB pathway
    • Nikolaidou-Neokosmidou V., Zannis V.I., Kardassis D. Inhibition of hepatocyte nuclear factor 4 transcriptional activity by the nuclear factor kappaB pathway. Biochem. J. 2006, 398(3):439-450.
    • (2006) Biochem. J. , vol.398 , Issue.3 , pp. 439-450
    • Nikolaidou-Neokosmidou, V.1    Zannis, V.I.2    Kardassis, D.3
  • 35
    • 67649826561 scopus 로고    scopus 로고
    • Mechanisms and genes in human strial presbycusis from animal models
    • Ohlemiller K.K. Mechanisms and genes in human strial presbycusis from animal models. Brain Res. 2009, 1277:70-83.
    • (2009) Brain Res. , vol.1277 , pp. 70-83
    • Ohlemiller, K.K.1
  • 36
    • 33748302837 scopus 로고    scopus 로고
    • Cellular correlates of age-related endocochlear potential reduction in a mouse model
    • Ohlemiller K.K., Lett J.M., Gagnon P.M. Cellular correlates of age-related endocochlear potential reduction in a mouse model. Hear. Res. 2006, 220(1-2):10-26.
    • (2006) Hear. Res. , vol.220 , Issue.1-2 , pp. 10-26
    • Ohlemiller, K.K.1    Lett, J.M.2    Gagnon, P.M.3
  • 37
    • 78650169848 scopus 로고    scopus 로고
    • Divergent aging characteristics in CBA/J and CBA/CaJ mouse cochleae
    • Ohlemiller K.K., Dahl A.R., Gagnon P.M. Divergent aging characteristics in CBA/J and CBA/CaJ mouse cochleae. J. Assoc. Res. Otolaryngol. 2010, 11(4):605-623.
    • (2010) J. Assoc. Res. Otolaryngol. , vol.11 , Issue.4 , pp. 605-623
    • Ohlemiller, K.K.1    Dahl, A.R.2    Gagnon, P.M.3
  • 38
    • 14844328611 scopus 로고    scopus 로고
    • Tissue-specific regulation of metabolic pathways through the transcriptional coactivator PGC1-alpha
    • Puigserver P. Tissue-specific regulation of metabolic pathways through the transcriptional coactivator PGC1-alpha. Int. J. Obes. (Lond.) 2005, 29(Suppl. 1):S5-S9.
    • (2005) Int. J. Obes. (Lond.) , vol.29 , Issue.SUPPL. 1
    • Puigserver, P.1
  • 39
    • 0037326196 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator
    • Puigserver P., Spiegelman B.M. Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. Endocr. Rev. 2003, 24(1):78-90.
    • (2003) Endocr. Rev. , vol.24 , Issue.1 , pp. 78-90
    • Puigserver, P.1    Spiegelman, B.M.2
  • 40
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • Puigserver P., Wu Z., Park C.W., Graves R., Wright M., Spiegelman B.M. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell. 1998, 92(6):829-839.
    • (1998) Cell. , vol.92 , Issue.6 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3    Graves, R.4    Wright, M.5    Spiegelman, B.M.6
  • 41
    • 0024518132 scopus 로고
    • Establishment of inner ear epithelial cell culture: isolation, growth and characterization
    • Rarey K.E., Patterson K. Establishment of inner ear epithelial cell culture: isolation, growth and characterization. Hear. Res. 1989, 38(3):277-287.
    • (1989) Hear. Res. , vol.38 , Issue.3 , pp. 277-287
    • Rarey, K.E.1    Patterson, K.2
  • 42
    • 33645011201 scopus 로고    scopus 로고
    • Nuclear control of respiratory gene expression in mammalian cells
    • Scarpulla R.C. Nuclear control of respiratory gene expression in mammalian cells. J. Cell. Biochem. 2006, 97(4):673-683.
    • (2006) J. Cell. Biochem. , vol.97 , Issue.4 , pp. 673-683
    • Scarpulla, R.C.1
  • 43
    • 57649148823 scopus 로고    scopus 로고
    • Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1-related coactivator
    • Scarpulla R.C. Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1-related coactivator. Ann. NY Acad. Sci. 2008, 1147:321-334.
    • (2008) Ann. NY Acad. Sci. , vol.1147 , pp. 321-334
    • Scarpulla, R.C.1
  • 44
    • 42049114034 scopus 로고    scopus 로고
    • Transcriptional paradigms in mammalian mitochondrial biogenesis and function
    • Scarpulla R.C. Transcriptional paradigms in mammalian mitochondrial biogenesis and function. Physiol. Rev. 2008, 88(2):611-638.
    • (2008) Physiol. Rev. , vol.88 , Issue.2 , pp. 611-638
    • Scarpulla, R.C.1
  • 45
    • 80053574426 scopus 로고    scopus 로고
    • Analysis of the common deletions in the mitochondrial DNA is a sensitive biomarker detecting direct and non-targeted cellular effects of low dose ionizing radiation
    • Schilling-Tóth B., Sándor N., Kis E., Kadhim M., Sáfrány G., Hegyesi H. Analysis of the common deletions in the mitochondrial DNA is a sensitive biomarker detecting direct and non-targeted cellular effects of low dose ionizing radiation. Mutat. Res. 2011, 716(1-2):33-39.
    • (2011) Mutat. Res. , vol.716 , Issue.1-2 , pp. 33-39
    • Schilling-Tóth, B.1    Sándor, N.2    Kis, E.3    Kadhim, M.4    Sáfrány, G.5    Hegyesi, H.6
  • 46
    • 75949155739 scopus 로고
    • Further observations on the pathology of presbycusis
    • Schuknecht H.F. Further observations on the pathology of presbycusis. Arch. Otolaryngol. 1964, 80:369-382.
    • (1964) Arch. Otolaryngol. , vol.80 , pp. 369-382
    • Schuknecht, H.F.1
  • 50
    • 0032969493 scopus 로고    scopus 로고
    • Advanced glycation in D-galactose induced mouse aging model
    • Song X., Bao M., Li D., Li Y.M. Advanced glycation in D-galactose induced mouse aging model. Mech. Ageing Dev. 1999, 108(3):239-251.
    • (1999) Mech. Ageing Dev. , vol.108 , Issue.3 , pp. 239-251
    • Song, X.1    Bao, M.2    Li, D.3    Li, Y.M.4
  • 51
    • 20444493535 scopus 로고    scopus 로고
    • Pathologic changes of presbycusis begin in secondary processes and spread to primary processes of strial marginal cells
    • Spicer S.S., Schulte B.A. Pathologic changes of presbycusis begin in secondary processes and spread to primary processes of strial marginal cells. Hear. Res. 2005, 205(1-2):225-240.
    • (2005) Hear. Res. , vol.205 , Issue.1-2 , pp. 225-240
    • Spicer, S.S.1    Schulte, B.A.2
  • 52
    • 21244476364 scopus 로고    scopus 로고
    • The aging myocardium: roles of mitochondrial damage and lysosomal degradation
    • Terman A., Brunk U.T. The aging myocardium: roles of mitochondrial damage and lysosomal degradation. Heart Lung Circ. 2005, 14(2):107-114.
    • (2005) Heart Lung Circ. , vol.14 , Issue.2 , pp. 107-114
    • Terman, A.1    Brunk, U.T.2
  • 53
    • 70350411987 scopus 로고    scopus 로고
    • Mitochondrial DNA deletion is a predisposing cause for sensorineural hearing loss
    • Ueda N., Oshima T., Ikeda K., Abe K., Aoki M., Takasaka T. Mitochondrial DNA deletion is a predisposing cause for sensorineural hearing loss. Laryngoscope 1998, 108(4 Pt 1):580-584.
    • (1998) Laryngoscope , vol.108 , Issue.4 PART 1 , pp. 580-584
    • Ueda, N.1    Oshima, T.2    Ikeda, K.3    Abe, K.4    Aoki, M.5    Takasaka, T.6
  • 54
    • 0028971289 scopus 로고
    • Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation. Source Laboratory of Genetics, Salk Institute, San Diego, California 92186-5800, USA
    • Verma I.M., Stevenson J.K., Schwarz E.M., Van Antwerp D., Miyamoto S. Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation. Source Laboratory of Genetics, Salk Institute, San Diego, California 92186-5800, USA. Genes Dev. 1995, 9(22):2723-2735.
    • (1995) Genes Dev. , vol.9 , Issue.22 , pp. 2723-2735
    • Verma, I.M.1    Stevenson, J.K.2    Schwarz, E.M.3    Van Antwerp, D.4    Miyamoto, S.5
  • 55
    • 0028011017 scopus 로고
    • Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: a potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis
    • Virbasius J.V., Scarpulla R.C. Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: a potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis. Proc. Natl. Acad. Sci. USA 1994, 91(4):1309-1313.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , Issue.4 , pp. 1309-1313
    • Virbasius, J.V.1    Scarpulla, R.C.2
  • 56
    • 0027135555 scopus 로고
    • NRF-1, an activator involved in nuclear-mitochondrial interactions, utilizes a new DNA-binding domain conserved in a family of developmental regulators
    • Virbasius C.A., Virbasius J.V., Scarpulla R.C. NRF-1, an activator involved in nuclear-mitochondrial interactions, utilizes a new DNA-binding domain conserved in a family of developmental regulators. Genes Dev. 1993, 7(12A):2431-2445.
    • (1993) Genes Dev. , vol.7 , Issue.12 A , pp. 2431-2445
    • Virbasius, C.A.1    Virbasius, J.V.2    Scarpulla, R.C.3
  • 58
    • 79959981721 scopus 로고    scopus 로고
    • Mitochondrial transcription factor A overexpression and base excision repair deficiency in the inner ear of rats with D-galactose-induced aging
    • Zhong Y., Hu Y.J., Chen B., Peng W., Sun Y., Yang Y., Zhao X.Y., Fan G.R., Huang X., Kong W.J. Mitochondrial transcription factor A overexpression and base excision repair deficiency in the inner ear of rats with D-galactose-induced aging. FEBS J. 2011, 278(14):2500-2510.
    • (2011) FEBS J. , vol.278 , Issue.14 , pp. 2500-2510
    • Zhong, Y.1    Hu, Y.J.2    Chen, B.3    Peng, W.4    Sun, Y.5    Yang, Y.6    Zhao, X.Y.7    Fan, G.R.8    Huang, X.9    Kong, W.J.10
  • 59
    • 79551490365 scopus 로고    scopus 로고
    • Metformin has adenosine-monophosphate activated protein kinase (AMPK)-independent effects on LPS-stimulated rat primary microglial cultures
    • Łabuzek K., Liber S., Gabryel B., Okopień B. Metformin has adenosine-monophosphate activated protein kinase (AMPK)-independent effects on LPS-stimulated rat primary microglial cultures. Pharmacol. Rep. 2010, 62(5):827-848.
    • (2010) Pharmacol. Rep. , vol.62 , Issue.5 , pp. 827-848
    • Łabuzek, K.1    Liber, S.2    Gabryel, B.3    Okopień, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.