Upregulation of human selenoprotein H in murine hippocampal neuronal cells promotes mitochondrial biogenesis and functional performance

Mitochondrion

Volumn 11, Issue 1, 2011, Pages 76-82

  Mendelev, Natalia ^a   Mehta, Suresh L ^a   Witherspoon, Sam ^a   He, Qingping ^a   Sexton, Jonathan Z ^a   Li, P Andy ^a  

^a NORTH CAROLINA CENTRAL UNIVERSITY   (United States)

Author keywords

Cell signaling; Mitochondrial biogenesis; Mitochondrial respiration; Mitochondrion; Neuron; Selenoprotein

Indexed keywords

CYTOCHROME C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SELENOPROTEIN; SELENOPROTEIN H; TRANSCRIPTION FACTOR NRF1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOGENESIS; CELL FUNCTION; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; HIPPOCAMPUS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; NERVE CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; ULTRAVIOLET B RADIATION; UPREGULATION;

ANIMALS; CELL LINE; CELL RESPIRATION; DNA-BINDING PROTEINS; HIGH MOBILITY GROUP PROTEINS; HIPPOCAMPUS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; NEURONS; NUCLEAR RESPIRATORY FACTOR 1; SELENOPROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSFECTION; UP-REGULATION;

MURINAE;

EID: 78650009028     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2010.07.007     Document Type: Article

References (12)

1. Ben Jilani K.E., Panee J., He Q., Berry M.J., Li P.A. Overexpression of selenoprotein H reduces Ht22 neuronal cell death after UVB irradiation by preventing superoxide formation. Int. J. Biol. Sci. 2007, 3:198-204.
2. Bergeron R., Ren J.M., Cadman K.S., Moore I.K., Perret P., Pypaert M., Young L.H., Semenkovich C.F., Shulman G.I. Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis. Am. J. Physiol. Endocrinol. Metab. 2001, 281:E1340-E1346.
3. Cogswell P.C., Kashatus D.F., Keifer J.A., Guttridge D.C., Reuther J.Y., Bristow C., Roy S., Nicholson D.W., Baldwin A.S. NF-kappa B and I kappa B alpha are found in the mitochondria. Evidence for regulation of mitochondrial gene expression by NF-kappa B. J. Biol. Chem. 2003, 278:2963-2968.
4. Kelly D.P., Scarpulla R.C. Transcriptional regulatory circuits controlling mitochondrial biogenesis and function. Genes Dev. 2004, 18:357-368.
5. Mendelev N., Witherspoon S., Li P.A. Overexpression of human selenoprotein H in neuronal cells ameliorates ultraviolet irradiation-induced damage by modulating cell signaling pathways. Exp. Neurol. 2009, 220:328-334.
6. Morozova N., Forry E.P., Shahid E., Zavacki A.M., Harney J.W., Kraytsberg Y., Berry M.J. Antioxidant function of a novel selenoprotein in Drosophila melanogaster. Genes Cells 2003, 8:963-971.
7. Novoselov S.V., Kryukov G.V., Xu X.M., Carlson B.A., Hatfield D.L., Gladyshev V.N. Selenoprotein H is a nucleolar thioredoxin-like protein with a unique expression pattern. J. Biol. Chem. 2007, 282:11960-11968.
8. Palomer X., Alvarez-Guardia D., Rodriguez-Calvo R., Coll T., Laguna J.C., Davidson M.M., Chan T.O., Feldman A.M., Vazquez-Carrera M. TNF-alpha reduces PGC-1alpha expression through NF-kappaB and p38 MAPK leading to increased glucose oxidation in a human cardiac cell model. Cardiovasc. Res. 2009, 81:703-712.
9. Panee J., Stoytcheva Z.R., Liu W., Berry M.J. Selenoprotein H is a redox-sensing high mobility group family DNA-binding protein that up-regulates genes involved in glutathione synthesis and phase II detoxification. J. Biol. Chem. 2007, 282:23759-23765.
10. Scarpulla R.C. Transcriptional activators and coactivators in the nuclear control of mitochondrial function in mammalian cells. Gene 2002, 286:81-89.
11. Scarpulla R.C. Transcriptional paradigms in mammalian mitochondrial biogenesis and function. Physiol. Rev. 2008, 88:611-638.
12. Wu Z., Puigserver P., Andersson U., Zhang C., Adelmant G., Mootha V., Troy A., Cinti S., Lowell B., Scarpulla R.C., Spiegelman B.M. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 1999, 98:115-124.