Tachykinin substance P signaling involved in diesel exhaust-induced bronchopulmonary neurogenic inflammation in rats

Archives of Toxicology

Volumn 77, Issue 11, 2003, Pages 638-650

  Wong, Simon S ^a   Sun, Nina N ^a   Keith, Ingegerd ^b   Kweon, Chol Bum ^c   Foster, David E ^c   Schauer, James J ^d   Witten, Mark L ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c University of Wisconsin Madison   (United States)

^d WISCONSIN STATE LABORATORY OF HYGIENE   (United States)

Author keywords

Diesel exhaust; Neurogenic inflammation; Neurokinin 1 receptor; Neutral endopeptidase; Particulate matter; Preprotachykinin gene; Substance P

Indexed keywords

CAPSAICIN; NEUROKININ 1 RECEPTOR; PREPROTACHYKININ; PROTEINASE; SUBSTANCE P; TACHYKININ;

AMBIENT AIR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHOPULMONARY NEUROGENIC INFLAMMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIESEL ENGINE; ENZYME REGULATION; EXHAUST GAS; EXTRAVASATION; FEMALE; GENE OVEREXPRESSION; INFLAMMATORY CELL; LUNG EDEMA; LUNG TOXICITY; NEUROTOXICITY; NONHUMAN; PARTICULATE MATTER; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RANDOMIZATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; BRONCHITIS; CAPSAICIN; ENDOPEPTIDASES; FEMALE; IMMUNOENZYME TECHNIQUES; IMMUNOHISTOCHEMISTRY; NERVE FIBERS, UNMYELINATED; NEUROGENIC INFLAMMATION; NEURONS, AFFERENT; PARTICLE SIZE; PNEUMONIA; RADIOPHARMACEUTICALS; RATS; RATS, INBRED F344; RECEPTORS, NEUROKININ-1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SUBSTANCE P; TECHNETIUM TC 99M AGGREGATED ALBUMIN; VEHICLE EMISSIONS;

ANIMALIA;

EID: 0344944045     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-003-0485-4     Document Type: Article

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