Diesel exhaust particulate-induced activation of Stat3 requires activities of EGFR and Src in airway epithelial cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 292, Issue 2, 2007, Pages

  Cao, Dongsun ^a   Tal, Tamara L ^b   Graves, Lee M ^a   Gilmour, Ian ^c   Linak, William ^c   Reed, William ^a   Bromberg, Philip A ^a   Samet, James M ^c  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Diesel exhaust particles; Epidermal growth factor receptor; Human airway epithelial cells; Reactive oxygen species; Signal transducer and activator of transcription 3

Indexed keywords

4 (3 BROMOANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ANTIOXIDANT; EPIDERMAL GROWTH FACTOR RECEPTOR; STAT3 PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CELL NUCLEUS; CYTOKINE RELEASE; CYTOPLASM; EXHAUST GAS; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; INHALATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION;

ADULT; CELL NUCLEUS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EPITHELIAL CELLS; HUMANS; OXIDATION-REDUCTION; OXIDATIVE STRESS; PARTICULATE MATTER; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN TRANSPORT; RECEPTOR, EPIDERMAL GROWTH FACTOR; RESPIRATORY SYSTEM; SRC-FAMILY KINASES; STAT3 TRANSCRIPTION FACTOR; TIME FACTORS; VEHICLE EMISSIONS;

EID: 33847076848     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00204.2006     Document Type: Article

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