CDK inhibitor p57Kip2 is downregulated by Akt during HER2-mediated tumorigenicity

Cell Cycle

Volumn 12, Issue 6, 2013, Pages 935-943

  Zhao, Ruiying ^a,b   Yang, Heng Yin ^a   Shin, Jihyun ^a,b   Phan, Liem ^a   Fang, Lekun ^a   Che, Ting Fang ^a   Su, Chun Hui ^a   Yeung, Sai Ching J ^a   Lee, Mong Hong ^a,b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Akt; Cell cycle; HER2; p57Kip2; Phosphorylation; Subcellular localization

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1C; EPIDERMAL GROWTH FACTOR RECEPTOR 2; PROTEIN KINASE B; SERINE; CYCLINE; ERBB2 PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE;

ARTICLE; ATTENUATION; BREAST TUMOR; CANCER SURVIVAL; CARCINOGENICITY; CELL PROLIFERATION; CELL TRANSFORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MOLECULAR STABILITY; OVERALL SURVIVAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TUMOR GROWTH; TURNOVER TIME; UBIQUITINATION; AKT; ANIMAL; CELL CYCLE; CELL STRAIN 3T3; CELL STRAIN HEK293; CELL SURVIVAL; FEMALE; GENETICS; HER2; METABOLISM; MOUSE; NUDE MOUSE; P57 KIP2; PATHOLOGY; PHOSPHORYLATION; SUBCELLULAR LOCALIZAITON; TUMOR CELL LINE;

AKT; CELL CYCLE; HER2; P57 KIP2; PHOSPHORYLATION; SUBCELLULAR LOCALIZAITON;

3T3 CELLS; ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN-DEPENDENT KINASE INHIBITOR P57; DOWN-REGULATION; FEMALE; HEK293 CELLS; HUMANS; MICE; MICE, NUDE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION; UBIQUITINATION;

EID: 84875150459     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.23883     Document Type: Article

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