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Volumn 11, Issue 24, 2012, Pages 4633-4641

CDK inhibitor p57Kip2 is negatively regulated by COP9 signalosome subunit 6

Author keywords

Cell cycle; COP9; CSN6; p57; Skp2

Indexed keywords

COP9 SIGNALOSOME; CSN6 PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1C; S PHASE KINASE ASSOCIATED PROTEIN 2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

EID: 84871512500     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.22887     Document Type: Article
Times cited : (28)

References (37)
  • 1
    • 0033545636 scopus 로고    scopus 로고
    • Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
    • PMID:10086358
    • Tomoda K, Kubota Y, Kato J. Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1. Nature 1999; 398:160-5; PMID:10086358; http://dx.doi.org/10.1038/18230.
    • (1999) Nature , vol.398 , pp. 160-165
    • Tomoda, K.1    Kubota, Y.2    Kato, J.3
  • 2
    • 0033544866 scopus 로고    scopus 로고
    • COP9 signalosome-directed c-Jun activation/stabilization is independent of JNK
    • PMID:10585392
    • Naumann M, Bech-Otschir D, Huang X, Ferrell K, Dubiel W. COP9 signalosome-directed c-Jun activation/stabilization is independent of JNK. J Biol Chem 1999; 274:35297-300; PMID:10585392; http://dx.doi.org/10.1074/jbc.274. 50.35297.
    • (1999) J Biol Chem , vol.274 , pp. 35297-35300
    • Naumann, M.1    Bech-Otschir, D.2    Huang, X.3    Ferrell, K.4    Dubiel, W.5
  • 3
    • 0035794541 scopus 로고    scopus 로고
    • COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system
    • PMID:11285227
    • Bech-Otschir D, Kraft R, Huang X, Henklein P, Kapelari B, Pollmann C, et al. COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system. EMBO J 2001; 20:1630-9; PMID:11285227; http://dx.doi.org/10. 1093/emboj/20.7.1630.
    • (2001) EMBO J , vol.20 , pp. 1630-1639
    • Bech-Otschir, D.1    Kraft, R.2    Huang, X.3    Henklein, P.4    Kapelari, B.5    Pollmann, C.6
  • 4
    • 79952205242 scopus 로고    scopus 로고
    • Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers
    • PMID:21317535
    • Zhao R, Yeung SC, Chen J, Iwakuma T, Su CH, Chen B, et al. Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers. J Clin Invest 2011; 121:851-65; PMID:21317535; http://dx.doi.org/10.1172/JCI44111.
    • (2011) J Clin Invest , vol.121 , pp. 851-865
    • Zhao, R.1    Yeung, S.C.2    Chen, J.3    Iwakuma, T.4    Su, C.H.5    Chen, B.6
  • 5
    • 40349087136 scopus 로고    scopus 로고
    • Roles for CSN5 in control of p53/MDM2 activities
    • PMID:17879958
    • Zhang XC, Chen J, Su CH, Yang HY, Lee MH. Roles for CSN5 in control of p53/MDM2 activities. J Cell Biochem 2008; 103:1219-30; PMID:17879958; http://dx.doi.org/10.1002/jcb.21504.
    • (2008) J Cell Biochem , vol.103 , pp. 1219-1230
    • Zhang, X.C.1    Chen, J.2    Su, C.H.3    Yang, H.Y.4    Lee, M.H.5
  • 6
    • 82455167963 scopus 로고    scopus 로고
    • COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σ
    • PMID:21625211
    • Choi HH, Gully C, Su CH, Velazquez-Torres G, Chou PC, Tseng C, et al. COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σ. Oncogene 2011; 30:4791-801; PMID:21625211; http://dx.doi.org/10.1038/onc.2011.192.
    • (2011) Oncogene , vol.30 , pp. 4791-4801
    • Choi, H.H.1    Gully, C.2    Su, C.H.3    Velazquez-Torres, G.4    Chou, P.C.5    Tseng, C.6
  • 7
    • 0344824691 scopus 로고    scopus 로고
    • The COP9 signalosome
    • PMID:14570571
    • Wei N, Deng XW. The COP9 signalosome. Annu Rev Cell Dev Biol 2003; 19:261-86; PMID:14570571; http://dx.doi.org/10.1146/annurev.cell-bio.19.111301. 112449.
    • (2003) Annu Rev Cell Dev Biol , vol.19 , pp. 261-286
    • Wei, N.1    Deng, X.W.2
  • 8
    • 80052873994 scopus 로고    scopus 로고
    • Roles of COP9 signalosome in cancer
    • PMID:21876386
    • Lee MH, Zhao R, Phan L, Yeung SC. Roles of COP9 signalosome in cancer. Cell Cycle 2011; 10:3057-66; PMID:21876386; http://dx.doi.org/10.4161/cc.10.18. 17320.
    • (2011) Cell Cycle , vol.10 , pp. 3057-3066
    • Lee, M.H.1    Zhao, R.2    Phan, L.3    Yeung, S.C.4
  • 9
    • 0033828048 scopus 로고    scopus 로고
    • The COP9 signalosome: From light signaling to general developmental regulation and back
    • PMID:11019806
    • Karniol B, Chamovitz DA. The COP9 signalosome: from light signaling to general developmental regulation and back. Curr Opin Plant Biol 2000; 3:387-93; PMID:11019806; http://dx.doi.org/10.1016/S1369-5266(00)00101-1.
    • (2000) Curr Opin Plant Biol , vol.3 , pp. 387-393
    • Karniol, B.1    Chamovitz, D.A.2
  • 10
    • 1542713819 scopus 로고    scopus 로고
    • The COP9 signalosome: An alternative lid for the 26S proteasome?
    • PMID:14507477
    • Li L, Deng XW. The COP9 signalosome: an alternative lid for the 26S proteasome? Trends Cell Biol 2003; 13:507-9; PMID:14507477; http://dx.doi.org/ 10.1016/j.tcb.2003.08.002.
    • (2003) Trends Cell Biol , vol.13 , pp. 507-509
    • Li, L.1    Deng, X.W.2
  • 11
    • 0028176483 scopus 로고
    • Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
    • PMID:8033212
    • Polyak K, Lee MH, Erdjument-Bromage H, Koff A, Roberts JM, Tempst P, et al. Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 1994; 78:59-66; PMID:8033212; http://dx.doi.org/10.1016/0092-8674(94)90572-X.
    • (1994) Cell , vol.78 , pp. 59-66
    • Polyak, K.1    Lee, M.H.2    Erdjument-Bromage, H.3    Koff, A.4    Roberts, J.M.5    Tempst, P.6
  • 12
    • 0028988158 scopus 로고
    • Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution
    • PMID:7729683
    • Lee MH, Reynisdóttir I, Massagué J. Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev 1995; 9:639-49; PMID:7729683; http://dx.doi.org/10.1101/ gad.9.6.639.
    • (1995) Genes Dev , vol.9 , pp. 639-649
    • Lee, M.H.1    Reynisdóttir, I.2    Massagué, J.3
  • 13
    • 0035193372 scopus 로고    scopus 로고
    • Negative regulators of cyclin-dependent kinases and their roles in cancers
    • PMID:11766887
    • Lee MH, Yang HY. Negative regulators of cyclin-dependent kinases and their roles in cancers. Cell Mol Life Sci 2001; 58:1907-22; PMID:11766887; http://dx.doi.org/10.1007/PL00000826.
    • (2001) Cell Mol Life Sci , vol.58 , pp. 1907-1922
    • Lee, M.H.1    Yang, H.Y.2
  • 14
    • 0030955563 scopus 로고    scopus 로고
    • Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development
    • PMID:9136926
    • Yan Y, Frisén J, Lee MH, Massagué J, Barbacid M. Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development. Genes Dev 1997; 11:973-83; PMID:9136926; http://dx.doi.org/10.1101/gad.11.8.973.
    • (1997) Genes Dev , vol.11 , pp. 973-983
    • Yan, Y.1    Frisén, J.2    Lee, M.H.3    Massagué, J.4    Barbacid, M.5
  • 15
    • 1842335753 scopus 로고    scopus 로고
    • Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith-Wiedemann syndrome
    • PMID:9144284
    • Zhang P, Liégeois NJ, Wong C, Finegold M, Hou H, Thompson JC, et al. Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith-Wiedemann syndrome. Nature 1997; 387:151-8; PMID:9144284; http://dx.doi.org/10.1038/387151a0.
    • (1997) Nature , vol.387 , pp. 151-158
    • Zhang, P.1    Liégeois, N.J.2    Wong, C.3    Finegold, M.4    Hou, H.5    Thompson, J.C.6
  • 16
    • 0038724743 scopus 로고    scopus 로고
    • Regulators of G1 cyclin-dependent kinases and cancers
    • PMID:12884917
    • Lee MH, Yang HY. Regulators of G1 cyclin-dependent kinases and cancers. Cancer Metastasis Rev 2003; 22:435-49; PMID:12884917; http://dx.doi.org/10.1023/ A:1023785332315.
    • (2003) Cancer Metastasis Rev , vol.22 , pp. 435-449
    • Lee, M.H.1    Yang, H.Y.2
  • 17
    • 79953840789 scopus 로고    scopus 로고
    • The hallmarks of CDKN1C (p57, KIP2) in cancer
    • PMID:21447370
    • Kavanagh E, Joseph B. The hallmarks of CDKN1C (p57, KIP2) in cancer. Biochim Biophys Acta 2011; 1816:50-6; PMID:21447370.
    • (2011) Biochim Biophys Acta , vol.1816 , pp. 50-56
    • Kavanagh, E.1    Joseph, B.2
  • 18
    • 77951553359 scopus 로고    scopus 로고
    • p57: A multifunctional protein in cancer
    • (Review). [Review] PMID:20428755
    • Guo H, Tian T, Nan KJ, Wang W. p57: A multifunctional protein in cancer (Review). [Review]. Int J Oncol 2010; 36:1321-9; PMID:20428755.
    • (2010) Int J Oncol , vol.36 , pp. 1321-1329
    • Guo, H.1    Tian, T.2    Nan, K.J.3    Wang, W.4
  • 20
    • 0041836324 scopus 로고    scopus 로고
    • Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation
    • PMID:12925736
    • Kamura T, Hara T, Kotoshiba S, Yada M, Ishida N, Imaki H, et al. Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation. Proc Natl Acad Sci USA 2003; 100:10231-6; PMID:12925736; http://dx.doi.org/10.1073/pnas. 1831009100.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10231-10236
    • Kamura, T.1    Hara, T.2    Kotoshiba, S.3    Yada, M.4    Ishida, N.5    Imaki, H.6
  • 21
    • 0035736487 scopus 로고    scopus 로고
    • HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
    • PMID:11715018
    • Zhou BP, Liao Y, Xia W, Zou Y, Spohn B, Hung MC. HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation. Nat Cell Biol 2001; 3:973-82; PMID:11715018; http://dx.doi.org/10.1038/ncb1101-973.
    • (2001) Nat Cell Biol , vol.3 , pp. 973-982
    • Zhou, B.P.1    Liao, Y.2    Xia, W.3    Zou, Y.4    Spohn, B.5    Hung, M.C.6
  • 22
    • 84869443068 scopus 로고    scopus 로고
    • HER2-Akt signaling in regulating COP9 signalsome subunit 6 and p53
    • PMID:23095642
    • Xue Y, Chen J, Choi HH, Phan L, Chou PC, Zhao R, et al. HER2-Akt signaling in regulating COP9 signalsome subunit 6 and p53. Cell Cycle 2012; 11:4181-90; PMID:23095642; http://dx.doi.org/10.4161/cc.22413.
    • (2012) Cell Cycle , vol.11 , pp. 4181-4190
    • Xue, Y.1    Chen, J.2    Choi, H.H.3    Phan, L.4    Chou, P.C.5    Zhao, R.6
  • 23
    • 28944448413 scopus 로고    scopus 로고
    • Identification of substrates for F-box proteins
    • PMID:16338364
    • Jin J, Ang XL, Shirogane T, Wade Harper J. Identification of substrates for F-box proteins. Methods Enzymol 2005; 399:287-309; PMID:16338364; http://dx.doi.org/10.1016/S0076-6879(05)99020-4.
    • (2005) Methods Enzymol , vol.399 , pp. 287-309
    • Jin, J.1    Ang, X.L.2    Shirogane, T.3    Wade Harper, J.4
  • 24
    • 0029053890 scopus 로고
    • A Saccharomyces cerevisiae gene essential for viability has been conserved in evolution
    • PMID:7628709
    • Rinaldi T, Bolotin-Fukuhara M, Frontali L. A Saccharomyces cerevisiae gene essential for viability has been conserved in evolution. Gene 1995; 160:135-6; PMID:7628709; http://dx.doi.org/10.1016/0378-1119(95)00212-O.
    • (1995) Gene , vol.160 , pp. 135-136
    • Rinaldi, T.1    Bolotin-Fukuhara, M.2    Frontali, L.3
  • 25
    • 14444278047 scopus 로고    scopus 로고
    • The Pad1+ gene encodes a subunit of the 26 S proteasome in fission yeast
    • PMID:9727008
    • Penney M, Wilkinson C, Wallace M, Javerzat JP, Ferrell K, Seeger M, et al. The Pad1+ gene encodes a subunit of the 26 S proteasome in fission yeast. J Biol Chem 1998; 273:23938-45; PMID:9727008; http://dx.doi.org/10.1074/jbc.273. 37.23938.
    • (1998) J Biol Chem , vol.273 , pp. 23938-23945
    • Penney, M.1    Wilkinson, C.2    Wallace, M.3    Javerzat, J.P.4    Ferrell, K.5    Seeger, M.6
  • 26
    • 0032993486 scopus 로고    scopus 로고
    • Making sense of the COP9 signalosome. A regulatory protein complex conserved from Arabidopsis to human
    • PMID:10203806
    • Wei N, Deng XW. Making sense of the COP9 signalosome. A regulatory protein complex conserved from Arabidopsis to human. Trends Genet 1999; 15:98-103; PMID:10203806; http://dx.doi.org/10.1016/S0168-9525(98)01670-9.
    • (1999) Trends Genet , vol.15 , pp. 98-103
    • Wei, N.1    Deng, X.W.2
  • 27
    • 34248350363 scopus 로고    scopus 로고
    • MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function
    • PMID:12370088
    • Maytal-Kivity V, Reis N, Hofmann K, Glickman MH. MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function. BMC Biochem 2002; 3:28; PMID:12370088; http://dx.doi.org/10.1186/1471-2091-3-28.
    • (2002) BMC Biochem , vol.3 , pp. 28
    • Maytal-Kivity, V.1    Reis, N.2    Hofmann, K.3    Glickman, M.H.4
  • 28
    • 0035906430 scopus 로고    scopus 로고
    • Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome
    • PMID:11337588
    • Lyapina S, Cope G, Shevchenko A, Serino G, Tsuge T, Zhou C, et al. Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. Science 2001; 292:1382-5; PMID:11337588; http://dx.doi.org/10.1126/science.1059780.
    • (2001) Science , vol.292 , pp. 1382-1385
    • Lyapina, S.1    Cope, G.2    Shevchenko, A.3    Serino, G.4    Tsuge, T.5    Zhou, C.6
  • 29
    • 51049115529 scopus 로고    scopus 로고
    • A new ubiquitin ligase involved in p57KIP2 proteolysis regulates osteoblast cell differentiation
    • PMID:18660753
    • Kim M, Nakamoto T, Nishimori S, Tanaka K, Chiba T. A new ubiquitin ligase involved in p57KIP2 proteolysis regulates osteoblast cell differentiation. EMBO Rep 2008; 9:878-84; PMID:18660753; http://dx.doi.org/10.1038/embor.2008.125.
    • (2008) EMBO Rep , vol.9 , pp. 878-884
    • Kim, M.1    Nakamoto, T.2    Nishimori, S.3    Tanaka, K.4    Chiba, T.5
  • 30
    • 84862992962 scopus 로고    scopus 로고
    • Mutations in the PCNA-binding domain of CDKN1C cause IMAGe syndrome
    • PMID:22634751
    • Arboleda VA, Lee H, Parnaik R, Fleming A, Banerjee A, Ferraz-de-Souza B, et al. Mutations in the PCNA-binding domain of CDKN1C cause IMAGe syndrome. Nat Genet 2012; 44:788-92; PMID:22634751; http://dx.doi.org/10.1038/ng.2275.
    • (2012) Nat Genet , vol.44 , pp. 788-792
    • Arboleda, V.A.1    Lee, H.2    Parnaik, R.3    Fleming, A.4    Banerjee, A.5    Ferraz-de-Souza, B.6
  • 31
    • 84862980829 scopus 로고    scopus 로고
    • Gain of function in CDKN1C
    • PMID:22735584
    • Riccio A, Cubellis MV. Gain of function in CDKN1C. Nat Genet 2012; 44:737-8; PMID:22735584; http://dx.doi.org/10.1038/ng.2336.
    • (2012) Nat Genet , vol.44 , pp. 737-738
    • Riccio, A.1    Cubellis, M.V.2
  • 32
    • 84869382398 scopus 로고    scopus 로고
    • A novel link between the HER2-Akt and MDM2-p53 pathways via CSN6
    • PMID:23099920
    • Iyer SV, Iwakuma T. A novel link between the HER2-Akt and MDM2-p53 pathways via CSN6. Cell Cycle 2012; 11:4112; PMID:23099920; http://dx.doi.org/ 10.4161/cc.22606.
    • (2012) Cell Cycle , vol.11 , pp. 4112
    • Iyer, S.V.1    Iwakuma, T.2
  • 33
    • 16244415180 scopus 로고    scopus 로고
    • Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity
    • PMID:15688030
    • Yang H, Zhao R, Yang HY, Lee MH. Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity. Oncogene 2005; 24:1924-35; PMID:15688030; http://dx.doi.org/10. 1038/sj.onc.1208352.
    • (2005) Oncogene , vol.24 , pp. 1924-1935
    • Yang, H.1    Zhao, R.2    Yang, H.Y.3    Lee, M.H.4
  • 34
    • 0029153609 scopus 로고
    • Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta
    • PMID:7649471
    • Reynisdóttir I, Polyak K, Iavarone A, Massagué J. Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta. Genes Dev 1995; 9:1831-45; PMID:7649471; http://dx.doi.org/10.1101/ gad.9.15.1831.
    • (1995) Genes Dev , vol.9 , pp. 1831-1845
    • Reynisdóttir, I.1    Polyak, K.2    Iavarone, A.3    Massagué, J.4
  • 35
    • 1642378661 scopus 로고    scopus 로고
    • Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
    • PMID:15014502
    • Bashir T, Dorrello NV, Amador V, Guardavaccaro D, Pagano M. Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase. Nature 2004; 428:190-3; PMID:15014502; http://dx.doi.org/10.1038/nature02330.
    • (2004) Nature , vol.428 , pp. 190-193
    • Bashir, T.1    Dorrello, N.V.2    Amador, V.3    Guardavaccaro, D.4    Pagano, M.5
  • 36
    • 0034725698 scopus 로고    scopus 로고
    • Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression
    • PMID:10767298
    • Laronga C, Yang HY, Neal C, Lee MH. Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression. J Biol Chem 2000; 275:23106-12; PMID:10767298; http://dx.doi.org/10.1074/jbc. M905616199.
    • (2000) J Biol Chem , vol.275 , pp. 23106-23112
    • Laronga, C.1    Yang, H.Y.2    Neal, C.3    Lee, M.H.4
  • 37
    • 0035927582 scopus 로고    scopus 로고
    • p27 Kip1 inhibits HER2/neu-mediated cell growth and tumorigenesis
    • PMID:11439332
    • Yang HY, Shao R, Hung MC, Lee MH. p27 Kip1 inhibits HER2/neu-mediated cell growth and tumorigenesis. Oncogene 2001; 20:3695-702; PMID:11439332; http://dx.doi.org/10.1038/sj.onc.1204472.
    • (2001) Oncogene , vol.20 , pp. 3695-3702
    • Yang, H.Y.1    Shao, R.2    Hung, M.C.3    Lee, M.H.4


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