TCEA3 binds to TGF-beta receptor I and induces Smad-independent, JNK-dependent apoptosis in ovarian cancer cells

Cellular Signalling

Volumn 25, Issue 5, 2013, Pages 1245-1251

  Cha, Young ^a,b   Kim, Dae Kwan ^a   Hyun, Jashil ^a   Kim, Seong Jin ^a   Park, Kyung Soon ^a  

^a CHA University   (South Korea)

^b MCLEAN HOSPITAL   (United States)

Author keywords

Apoptosis; Caspase; JNK; Ovarian cancer; TCEA3; TGF receptor I

Indexed keywords

CASPASE 3; CASPASE 8; LAMIN B; MESSENGER RNA; PROCASPASE 3; PROCASPASE 8; PROCASPASE 9; SMAD2 PROTEIN; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION ELONGATION FACTOR; TRANSCRIPTION ELONGATION FACTOR TCEA1; TRANSCRIPTION ELONGATION FACTOR TCEA2; TRANSCRIPTION ELONGATION FACTOR TCEA3; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 3; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CELL DESTRUCTION; CELL STRAIN HEK293; CELL SURVIVAL; CONTROLLED STUDY; DNA FRAGMENTATION; EMBRYO; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MOLECULAR DYNAMICS; OVARY CANCER; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

APOPTOSIS; CASPASES; CELL LINE, TUMOR; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SMAD PROTEINS; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTIONAL ELONGATION FACTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84875102066     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2013.01.016     Document Type: Article

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