Assessment of bitter taste of pharmaceuticals with multisensor system employing 3 way PLS regression

Analytica Chimica Acta

Volumn 770, Issue , 2013, Pages 45-52

  Rudnitskaya, Alisa ^a   Kirsanov, Dmitry ^b   Blinova, Yulia ^b   Legin, Evgeny ^c   Seleznev, Boris ^b   Clapham, David ^d   Ives, Robert S ^d   Saunders, Kenneth A ^d   Legin, Andrey ^b  

^a UNIVERSITY OF AVEIRO   (Portugal)

^b ST PETERSBURG STATE UNIVERSITY   (Russian Federation)

^c Sensor Systems LLC   (Russian Federation)

^d GLAXOSMITHKLINE   (United Kingdom)

Author keywords

API; Bitterness; Electronic tongue; N Way PLS regression; Potentiometric chemical sensors

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENTS; API; AVERAGE RELATIVE ERROR; BITTERNESS; PLS REGRESSION; POTASSIUM NITRATE; POTENTIOMETRIC; REGRESSION MODEL;

ELECTRONIC TONGUES; POTENTIOMETERS (ELECTRIC MEASURING INSTRUMENTS); RATS; REGRESSION ANALYSIS; SENSORS;

APPLICATION PROGRAMMING INTERFACES (API);

AZELASTINE; CAFFEINE; CHLORHEXIDINE; NARATRIPTAN; PARACETAMOL; POTASSIUM NITRATE; QUININE; SUMATRIPTAN;

ACIDITY; ADULT; ANIMAL EXPERIMENT; ARTICLE; BITTER TASTE; CALIBRATION; CONTROLLED STUDY; ELECTRONIC TONGUE SENSOR SYSTEM; FEMALE; HUMAN; HUMAN EXPERIMENT; IONIZATION; LIPOPHILICITY; MALE; NONHUMAN; PH; POTENTIOMETRY; PREDICTIVE VALUE; PRIORITY JOURNAL; RAT; SCORING SYSTEM; SENSOR; STIMULUS RESPONSE; TASTE AVERSION; VALIDITY;

ADULT; ANIMALS; BIOSENSING TECHNIQUES; CAFFEINE; ELECTRONICS; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; PHTHALAZINES; POTENTIOMETRY; RATS; TASTE;

APIS; RATTUS;

EID: 84874979461     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2013.02.006     Document Type: Article

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