Functional expression and regulation of drug transporters in monolayer- and sandwich-cultured mouse hepatocytes

European Journal of Pharmaceutical Sciences

Volumn 49, Issue 1, 2013, Pages 39-50

  Noel, Gregory ^a   Le Vee, Marc ^a   Moreau, Amélie ^b   Stieger, Bruno ^c   Parmentier, Yannick ^b   Fardel, Olivier ^a,d  

^a UNIVERSITÉ DE RENNES 1   (France)

^b INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^d RENNES UNIVERSITY HOSPITAL   (France)

Author keywords

Drug transporters; Monolayer; Mouse; Primary hepatocytes; Regulation; Sandwich

Indexed keywords

ABC TRANSPORTER; AROMATIC HYDROCARBON RECEPTOR; CARRIER PROTEIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; MULTIDRUG RESISTANCE PROTEIN 5; MULTIDRUG RESISTANCE PROTEIN 6; OAT2 PROTEIN; OCTAMER TRANSCRIPTION FACTOR 1; PREGNANE X RECEPTOR; TAUROCHOLIC ACID; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ANIMAL CELL; ARTICLE; CELL ISOLATION; CELLULAR DISTRIBUTION; DOWN REGULATION; FLUORESCENCE MICROSCOPY; IN VITRO STUDY; LIVER CELL; MICROSCOPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; UPREGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECTS; FEMALE; GENETICS; METABOLISM; PROCEDURES; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; CELL CULTURE TECHNIQUES; CELLS, CULTURED; FEMALE; HEPATOCYTES; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED C57BL; RNA, MESSENGER; XENOBIOTICS;

EID: 84874939368     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2013.01.013     Document Type: Article

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