Integrin signaling in control of tumor growth and progression

International Journal of Biochemistry and Cell Biology

Volumn 45, Issue 5, 2013, Pages 1012-1015

  Xiong, Jiangling ^a   Balcioglu, Hayri E ^a   Danen, Erik H J ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Adhesion; Cancer; Integrins; Metastasis; Signaling

Indexed keywords

COLLAGEN RECEPTOR; INTEGRIN; PROTEIN P53;

ADHESION; ARTICLE; BREAST CANCER; CANCER GROWTH; CELL ADHESION; CELL CYCLE PROGRESSION; CELL INTERACTION; CELL PROLIFERATION; CELL SURVIVAL; CHEMICAL CUE; CLINICAL TRIAL (TOPIC); CONFORMATIONAL TRANSITION; EPITHELIUM CELL; EXTRACELLULAR MATRIX; HUMAN; NEOPLASM; NONHUMAN; PROSTATE ADENOCARCINOMA; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

EID: 84874937961     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2013.02.005     Document Type: Short Survey

References (30)

1. P.C. Brooks, S. Stromblad, R. Klemke, D. Visscher, F.H. Sarkar, and D.A. Cheresh Antiintegrin alpha-v-beta-3 blocks human breast cancer growth and angiogenesis in human skin Journal of Clinical Investigation 96 1995 1815 1822
2. E.H. Danen, P. Sonneveld, A. Sonnenberg, and K.M. Yamada Dual stimulation of Ras/mitogen-activated protein kinase and RhoA by cell adhesion to fibronectin supports growth factor-stimulated cell cycle progression Journal of Cell Biology 151 2000 1413 1422
3. I. Eke, Y. Deuse, S. Hehlgans, K. Gurtner, M. Krause, and M. Baumann Beta(1)integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy Journal of Clinical Investigation 122 2012 1529 1540
4. B. Felding-Habermann, B.M. Mueller, C.A. Romerdahl, and D.A. Cheresh Involvement of integrin alpha V gene expression in human melanoma tumorigenicity Journal of Clinical Investigation 89 1992 2018 2022
5. J.C. Friedland, M.H. Lee, and D. Boettiger Mechanically activated integrin switch controls alpha5beta1 function Science 323 2009 642 644
6. S.M. Frisch, and R.A. Screaton Anoikis mechanisms Current Opinion in Cell Biology 13 2001 555 562
7. L. Huck, S.M. Pontier, D.M. Zuo, and W.J. Muller Beta 1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression Proceedings of the National Academy of Sciences of the United States of America 107 2010 15559 15564
8. R.O. Hynes Integrins: bidirectional, allosteric signaling machines Cell 110 2002 673 687
9. E.A. Klein, L. Yin, D. Kothapalli, P. Castagnino, F.J. Byfield, and T. Xu Cell-cycle control by physiological matrix elasticity and in vivo tissue stiffening Current Biology 19 2009 1511 1518
10. A. Kren, V. Baeriswyl, F. Lehembre, C. Wunderlin, K. Strittmatter, and H. Antoniadis Increased tumor cell dissemination and cellular senescence in the absence of beta(1)-integrin function Embo Journal 26 2007 2832 2842
11. H. Lahlou, V. Sanguin-Gendreau, D. Zuo, R.D. Cardiff, G.W. McLean, and M.C. Frame Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression Proceedings of the National Academy of Sciences of the United States of America 104 2007 20302 20307
12. K.R. Levental, H.M. Yu, L. Kass, J.N. Lakins, M. Egeblad, and J.T. Erler Matrix crosslinking forces tumor progression by enhancing integrin signaling Cell 139 2009 891 906
13. S.T. Lim, X.L. Chen, Y. Lim, D.A. Hanson, T.T. Vo, and K. Howerton Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation Molecular Cell 29 2008 9 22
14. M. Luo, H. Fan, T. Nagy, H. Wei, C. Wang, and S. Liu Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells Cancer Research 69 2009 466 474
15. A. Mammoto, and D.E. Ingber Cytoskeletal control of growth and cell fate switching Current Opinion in Cell Biology 21 2009 864 870
16. C. Margadant, and A. Sonnenberg Integrin-TGF-beta crosstalk in fibrosis, cancer and wound healing EMBO Reports 11 2010 97 105
17. G.W. McLean, N.H. Komiyama, B. Serrels, H. Asano, L. Reynolds, and F. Conti Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression Genes and Development 18 2004 2998 3003
18. S.W. Moore, P. Roca-Cusachs, and M.P. Sheetz Stretchy proteins on stretchy substrates: the important elements of integrin-mediated rigidity sensing Developmental Cell 19 2010 194 206
19. K. Moran-Jones, A. Ledger, and M.J. Naylor Beta 1 integrin deletion enhances progression of prostate cancer in the TRAMP mouse model Scientific Reports 2 2012 526
20. P.A. Muller, P.T. Caswell, B. Doyle, M.P. Iwanicki, E.H. Tan, and S. Karim Mutant p53 drives invasion by promoting integrin recycling Cell 139 2009 1327 1341
21. J.M. Nam, Y. Onodera, M.J. Bissell, and C.C. Park Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin Cancer Research 70 2010 5238 5248
22. T. Plath, K. Detjen, M. Welzel, Z. von Marschall, D. Murphy, and M. Schirner A novel function for the tumor suppressor p16(INK4a): induction of anoikis via upregulation of the alpha(5)beta(1) fibronectin receptor Journal of Cell Biology 150 2000 1467 1478
23. P.P. Provenzano, D.R. Inman, K.W. Eliceiri, H.E. Beggs, and P.J. Keely Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer American Journal of Pathology 173 2008 1551 1565
24. Y. Pylayeva, K.M. Gillen, W. Gerald, H.E. Beggs, L.F. Reichardt, and F.G. Giancotti Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling Journal of Clinical Investigation 119 2009 252 266
25. N.E. Ramirez, Z.H. Zhang, A. Madamanchi, K.L. Boyd, L.D. O'Rear, and A. Nashabi The alpha(2)beta(1) integrin is a metastasis suppressor in mouse models and human cancer Journal of Clinical Investigation 121 2011 226 237
26. A.R. Reynolds, I.R. Hart, A.R. Watson, J.C. Welti, R.G. Silva, and S.D. Robinson Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors Nature Medicine 15 2009 392 400
27. T. Thuy, B. Barlow, L. O'Rear, B. Jarvis, Z. Li, and K. Dickeson Loss of the alpha 2 beta 1 integrin alters human papilloma virus-induced squamous carcinoma progression in vivo and in vitro PLoS ONE 6 2011 e26858
28. G. von Wichert, D. Krndija, H. Schmid, G. von Wichert, G. Haerter, and G. Adler Focal adhesion kinase mediates defects in the force-dependent reinforcement of initial integrin-cytoskeleton linkages in metastatic colon cancer cell lines European Journal of Cell Biology 87 2008 1 16
29. P. Wang, C. Ballestrem, and C.H. Streuli The C terminus of talin links integrins to cell cycle progression Journal of Cell Biology 195 2011 499 513
30. D.E. White, N.A. Kurpios, D.M. Zuo, J.A. Hassell, S. Blaess, and U. Mueller Targeted disruption of beta 1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction Cancer Cell 6 2004 159 170