-
1
-
-
0030662605
-
ErbB kinases and NDF signaling in human prostate cancer cells
-
Grasso AW, et al. (1997) ErbB kinases and NDF signaling in human prostate cancer cells. Oncogene 15:2705-2716.
-
(1997)
Oncogene
, vol.15
, pp. 2705-2716
-
-
Grasso, A.W.1
-
2
-
-
33746764457
-
Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis
-
Guo W, et al. (2006) Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis. Cell 126:489-502.
-
(2006)
Cell
, vol.126
, pp. 489-502
-
-
Guo, W.1
-
3
-
-
34250859492
-
Increased tumor cell dissemination and cellular senescence in the absence of beta1-integrin function
-
Kren A, et al. (2007) Increased tumor cell dissemination and cellular senescence in the absence of beta1-integrin function. EMBO J 26:2832-2842.
-
(2007)
EMBO J
, vol.26
, pp. 2832-2842
-
-
Kren, A.1
-
4
-
-
5144235557
-
Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction
-
White DE, et al. (2004) Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction. Cancer Cell 6:159-170.
-
(2004)
Cancer Cell
, vol.6
, pp. 159-170
-
-
White, D.E.1
-
5
-
-
49249107671
-
Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts
-
Park CC, Zhang HJ, Yao ES, Park CJ, Bissell MJ (2008) Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts. Cancer Res 68:4398-4405.
-
(2008)
Cancer Res
, vol.68
, pp. 4398-4405
-
-
Park, C.C.1
Zhang, H.J.2
Yao, E.S.3
Park, C.J.4
Bissell, M.J.5
-
6
-
-
38049098089
-
Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression
-
Lahlou H, et al. (2007) Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression. Proc Natl Acad Sci USA 104:20302-20307.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20302-20307
-
-
Lahlou, H.1
-
7
-
-
10644280092
-
Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression
-
McLean GW, et al. (2004) Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression. Genes Dev 18:2998-3003.
-
(2004)
Genes Dev
, vol.18
, pp. 2998-3003
-
-
McLean, G.W.1
-
8
-
-
55349105491
-
Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer
-
Provenzano PP, Inman DR, Eliceiri KW, Beggs HE, Keely PJ (2008) Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer. Am J Pathol 173:1551-1565.
-
(2008)
Am J Pathol
, vol.173
, pp. 1551-1565
-
-
Provenzano, P.P.1
Inman, D.R.2
Eliceiri, K.W.3
Beggs, H.E.4
Keely, P.J.5
-
9
-
-
61749094852
-
Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling
-
Pylayeva Y, et al. (2009) Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling. J Clin Invest 119:252-266.
-
(2009)
J Clin Invest
, vol.119
, pp. 252-266
-
-
Pylayeva, Y.1
-
10
-
-
0027954475
-
Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice
-
Guy CT, Muthuswamy SK, Cardiff RD, Soriano P, Muller WJ (1994) Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice. Genes Dev 8:23-32.
-
(1994)
Genes Dev
, vol.8
, pp. 23-32
-
-
Guy, C.T.1
Muthuswamy, S.K.2
Cardiff, R.D.3
Soriano, P.4
Muller, W.J.5
-
11
-
-
77953477155
-
Integrin-linked kinase has a critical role in ErbB2 mammary tumor progression: Implications for human breast cancer
-
Pontier SM, et al. (2010) Integrin-linked kinase has a critical role in ErbB2 mammary tumor progression: implications for human breast cancer. Oncogene 29:3374-3385.
-
(2010)
Oncogene
, vol.29
, pp. 3374-3385
-
-
Pontier, S.M.1
-
12
-
-
70149099358
-
Identification of a Stat3-dependent transcription regulatory network involved in metastatic progression
-
Ranger JJ, Levy DE, Shahalizadeh S, Hallett M, Muller WJ (2009) Identification of a Stat3-dependent transcription regulatory network involved in metastatic progression. Cancer Res 69:6823-6830.
-
(2009)
Cancer Res
, vol.69
, pp. 6823-6830
-
-
Ranger, J.J.1
Levy, D.E.2
Shahalizadeh, S.3
Hallett, M.4
Muller, W.J.5
-
13
-
-
40949130063
-
ShcA signalling is essential for tumour progression in mouse models of human breast cancer
-
DOI 10.1038/emboj.2008.22, PII EMBOJ200822
-
Ursini-Siegel J, et al. (2008) ShcA signalling is essential for tumour progression in mouse models of human breast cancer. EMBO J 27:910-920. (Pubitemid 351417168)
-
(2008)
EMBO Journal
, vol.27
, Issue.6
, pp. 910-920
-
-
Ursini-Siegel, J.1
Hardy, W.R.2
Zuo, D.3
Lam, S.H.L.4
Sanguin-Gendreau, V.5
Cardiff, R.D.6
Pawson, T.7
Muller, W.J.8
-
14
-
-
0030608876
-
Beta 1 integrin is essential for teratoma growth and angiogenesis
-
Bloch W, et al. (1997) Beta 1 integrin is essential for teratoma growth and angiogenesis. J Cell Biol 139:265-278.
-
(1997)
J Cell Biol
, vol.139
, pp. 265-278
-
-
Bloch, W.1
-
15
-
-
0036142782
-
The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis
-
Senger DR, et al. (2002) The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis. Am J Pathol 160:195-204.
-
(2002)
Am J Pathol
, vol.160
, pp. 195-204
-
-
Senger, D.R.1
-
16
-
-
53749092962
-
Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments
-
Caswell PT, et al. (2008) Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments. J Cell Biol 183:143-155.
-
(2008)
J Cell Biol
, vol.183
, pp. 143-155
-
-
Caswell, P.T.1
-
17
-
-
60549107350
-
An activating beta1 integrin mutation increases the conversion of benign to malignant skin tumors
-
Ferreira M, Fujiwara H, Morita K, Watt FM (2009) An activating beta1 integrin mutation increases the conversion of benign to malignant skin tumors. Cancer Res 69:1334-1342.
-
(2009)
Cancer Res
, vol.69
, pp. 1334-1342
-
-
Ferreira, M.1
Fujiwara, H.2
Morita, K.3
Watt, F.M.4
-
18
-
-
0030936450
-
Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies
-
Weaver VM, et al. (1997) Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol 137:231-245.
-
(1997)
J Cell Biol
, vol.137
, pp. 231-245
-
-
Weaver, V.M.1
-
19
-
-
72249100428
-
Mutant p53 drives invasion by promoting integrin recycling
-
Muller PA, et al. (2009) Mutant p53 drives invasion by promoting integrin recycling. Cell 139:1327-1341.
-
(2009)
Cell
, vol.139
, pp. 1327-1341
-
-
Muller, P.A.1
-
20
-
-
32944469169
-
Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo
-
Park CC, et al. (2006) Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo. Cancer Res 66:1526-1535.
-
(2006)
Cancer Res
, vol.66
, pp. 1526-1535
-
-
Park, C.C.1
-
21
-
-
77954353421
-
Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin
-
Nam JM, Onodera Y, Bissell MJ, Park CC (2010) Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin. Cancer Res 70:5238-5248.
-
(2010)
Cancer Res
, vol.70
, pp. 5238-5248
-
-
Nam, J.M.1
Onodera, Y.2
Bissell, M.J.3
Park, C.C.4
-
22
-
-
66449104669
-
Inhibition of vimentin or beta1 integrin reverts morphology of prostate tumor cells grown in laminin-rich extracellular matrix gels and reduces tumor growth in vivo
-
Zhang X, et al. (2009) Inhibition of vimentin or beta1 integrin reverts morphology of prostate tumor cells grown in laminin-rich extracellular matrix gels and reduces tumor growth in vivo. Mol Cancer Ther 8:499-508.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 499-508
-
-
Zhang, X.1
-
23
-
-
77953540958
-
HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment
-
Weigelt B, Lo AT, Park CC, Gray JW, Bissell MJ (2010) HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment. Breast Cancer Res Treat 122:35-43.
-
(2010)
Breast Cancer Res Treat
, vol.122
, pp. 35-43
-
-
Weigelt, B.1
Lo, A.T.2
Park, C.C.3
Gray, J.W.4
Bissell, M.J.5
-
25
-
-
62549115236
-
PALB2 links BRCA1 and BRCA2 in the DNA-damage response
-
Zhang F, et al. (2009) PALB2 links BRCA1 and BRCA2 in the DNA-damage response. Curr Biol 19:524-529.
-
(2009)
Curr Biol
, vol.19
, pp. 524-529
-
-
Zhang, F.1
-
26
-
-
0037666792
-
Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation
-
Troussard AA, et al. (2003) Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation. J Biol Chem 278:22374-22378.
-
(2003)
J Biol Chem
, vol.278
, pp. 22374-22378
-
-
Troussard, A.A.1
-
27
-
-
0038148536
-
Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes
-
Terpstra L, et al. (2003) Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes. J Cell Biol 162:139-148.
-
(2003)
J Cell Biol
, vol.162
, pp. 139-148
-
-
Terpstra, L.1
|