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Volumn 107, Issue 35, 2010, Pages 15559-15564

β1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression

Author keywords

Metastasis; Tumorigenesis

Indexed keywords

BETA1 INTEGRIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; CD31 ANTIGEN; KI 67 ANTIGEN;

EID: 77957283664     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1003034107     Document Type: Article
Times cited : (102)

References (27)
  • 1
    • 0030662605 scopus 로고    scopus 로고
    • ErbB kinases and NDF signaling in human prostate cancer cells
    • Grasso AW, et al. (1997) ErbB kinases and NDF signaling in human prostate cancer cells. Oncogene 15:2705-2716.
    • (1997) Oncogene , vol.15 , pp. 2705-2716
    • Grasso, A.W.1
  • 2
    • 33746764457 scopus 로고    scopus 로고
    • Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis
    • Guo W, et al. (2006) Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis. Cell 126:489-502.
    • (2006) Cell , vol.126 , pp. 489-502
    • Guo, W.1
  • 3
    • 34250859492 scopus 로고    scopus 로고
    • Increased tumor cell dissemination and cellular senescence in the absence of beta1-integrin function
    • Kren A, et al. (2007) Increased tumor cell dissemination and cellular senescence in the absence of beta1-integrin function. EMBO J 26:2832-2842.
    • (2007) EMBO J , vol.26 , pp. 2832-2842
    • Kren, A.1
  • 4
    • 5144235557 scopus 로고    scopus 로고
    • Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction
    • White DE, et al. (2004) Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction. Cancer Cell 6:159-170.
    • (2004) Cancer Cell , vol.6 , pp. 159-170
    • White, D.E.1
  • 5
    • 49249107671 scopus 로고    scopus 로고
    • Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts
    • Park CC, Zhang HJ, Yao ES, Park CJ, Bissell MJ (2008) Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts. Cancer Res 68:4398-4405.
    • (2008) Cancer Res , vol.68 , pp. 4398-4405
    • Park, C.C.1    Zhang, H.J.2    Yao, E.S.3    Park, C.J.4    Bissell, M.J.5
  • 6
    • 38049098089 scopus 로고    scopus 로고
    • Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression
    • Lahlou H, et al. (2007) Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression. Proc Natl Acad Sci USA 104:20302-20307.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 20302-20307
    • Lahlou, H.1
  • 7
    • 10644280092 scopus 로고    scopus 로고
    • Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression
    • McLean GW, et al. (2004) Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression. Genes Dev 18:2998-3003.
    • (2004) Genes Dev , vol.18 , pp. 2998-3003
    • McLean, G.W.1
  • 8
    • 55349105491 scopus 로고    scopus 로고
    • Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer
    • Provenzano PP, Inman DR, Eliceiri KW, Beggs HE, Keely PJ (2008) Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer. Am J Pathol 173:1551-1565.
    • (2008) Am J Pathol , vol.173 , pp. 1551-1565
    • Provenzano, P.P.1    Inman, D.R.2    Eliceiri, K.W.3    Beggs, H.E.4    Keely, P.J.5
  • 9
    • 61749094852 scopus 로고    scopus 로고
    • Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling
    • Pylayeva Y, et al. (2009) Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling. J Clin Invest 119:252-266.
    • (2009) J Clin Invest , vol.119 , pp. 252-266
    • Pylayeva, Y.1
  • 10
    • 0027954475 scopus 로고
    • Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice
    • Guy CT, Muthuswamy SK, Cardiff RD, Soriano P, Muller WJ (1994) Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice. Genes Dev 8:23-32.
    • (1994) Genes Dev , vol.8 , pp. 23-32
    • Guy, C.T.1    Muthuswamy, S.K.2    Cardiff, R.D.3    Soriano, P.4    Muller, W.J.5
  • 11
    • 77953477155 scopus 로고    scopus 로고
    • Integrin-linked kinase has a critical role in ErbB2 mammary tumor progression: Implications for human breast cancer
    • Pontier SM, et al. (2010) Integrin-linked kinase has a critical role in ErbB2 mammary tumor progression: implications for human breast cancer. Oncogene 29:3374-3385.
    • (2010) Oncogene , vol.29 , pp. 3374-3385
    • Pontier, S.M.1
  • 12
    • 70149099358 scopus 로고    scopus 로고
    • Identification of a Stat3-dependent transcription regulatory network involved in metastatic progression
    • Ranger JJ, Levy DE, Shahalizadeh S, Hallett M, Muller WJ (2009) Identification of a Stat3-dependent transcription regulatory network involved in metastatic progression. Cancer Res 69:6823-6830.
    • (2009) Cancer Res , vol.69 , pp. 6823-6830
    • Ranger, J.J.1    Levy, D.E.2    Shahalizadeh, S.3    Hallett, M.4    Muller, W.J.5
  • 14
    • 0030608876 scopus 로고    scopus 로고
    • Beta 1 integrin is essential for teratoma growth and angiogenesis
    • Bloch W, et al. (1997) Beta 1 integrin is essential for teratoma growth and angiogenesis. J Cell Biol 139:265-278.
    • (1997) J Cell Biol , vol.139 , pp. 265-278
    • Bloch, W.1
  • 15
    • 0036142782 scopus 로고    scopus 로고
    • The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis
    • Senger DR, et al. (2002) The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis. Am J Pathol 160:195-204.
    • (2002) Am J Pathol , vol.160 , pp. 195-204
    • Senger, D.R.1
  • 16
    • 53749092962 scopus 로고    scopus 로고
    • Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments
    • Caswell PT, et al. (2008) Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments. J Cell Biol 183:143-155.
    • (2008) J Cell Biol , vol.183 , pp. 143-155
    • Caswell, P.T.1
  • 17
    • 60549107350 scopus 로고    scopus 로고
    • An activating beta1 integrin mutation increases the conversion of benign to malignant skin tumors
    • Ferreira M, Fujiwara H, Morita K, Watt FM (2009) An activating beta1 integrin mutation increases the conversion of benign to malignant skin tumors. Cancer Res 69:1334-1342.
    • (2009) Cancer Res , vol.69 , pp. 1334-1342
    • Ferreira, M.1    Fujiwara, H.2    Morita, K.3    Watt, F.M.4
  • 18
    • 0030936450 scopus 로고    scopus 로고
    • Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies
    • Weaver VM, et al. (1997) Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol 137:231-245.
    • (1997) J Cell Biol , vol.137 , pp. 231-245
    • Weaver, V.M.1
  • 19
    • 72249100428 scopus 로고    scopus 로고
    • Mutant p53 drives invasion by promoting integrin recycling
    • Muller PA, et al. (2009) Mutant p53 drives invasion by promoting integrin recycling. Cell 139:1327-1341.
    • (2009) Cell , vol.139 , pp. 1327-1341
    • Muller, P.A.1
  • 20
    • 32944469169 scopus 로고    scopus 로고
    • Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo
    • Park CC, et al. (2006) Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo. Cancer Res 66:1526-1535.
    • (2006) Cancer Res , vol.66 , pp. 1526-1535
    • Park, C.C.1
  • 21
    • 77954353421 scopus 로고    scopus 로고
    • Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin
    • Nam JM, Onodera Y, Bissell MJ, Park CC (2010) Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin. Cancer Res 70:5238-5248.
    • (2010) Cancer Res , vol.70 , pp. 5238-5248
    • Nam, J.M.1    Onodera, Y.2    Bissell, M.J.3    Park, C.C.4
  • 22
    • 66449104669 scopus 로고    scopus 로고
    • Inhibition of vimentin or beta1 integrin reverts morphology of prostate tumor cells grown in laminin-rich extracellular matrix gels and reduces tumor growth in vivo
    • Zhang X, et al. (2009) Inhibition of vimentin or beta1 integrin reverts morphology of prostate tumor cells grown in laminin-rich extracellular matrix gels and reduces tumor growth in vivo. Mol Cancer Ther 8:499-508.
    • (2009) Mol Cancer Ther , vol.8 , pp. 499-508
    • Zhang, X.1
  • 23
    • 77953540958 scopus 로고    scopus 로고
    • HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment
    • Weigelt B, Lo AT, Park CC, Gray JW, Bissell MJ (2010) HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment. Breast Cancer Res Treat 122:35-43.
    • (2010) Breast Cancer Res Treat , vol.122 , pp. 35-43
    • Weigelt, B.1    Lo, A.T.2    Park, C.C.3    Gray, J.W.4    Bissell, M.J.5
  • 24
    • 68849092564 scopus 로고    scopus 로고
    • Genomic amplicons target vesicle recycling in breast cancer
    • 10.1172/JCI40256
    • Mills GB, Jurisica I, Yarden Y, Norma JC (2009) Genomic amplicons target vesicle recycling in breast cancer. J Clin Invest, 10.1172/JCI40256.
    • (2009) J Clin Invest
    • Mills, G.B.1    Jurisica, I.2    Yarden, Y.3    Norma, J.C.4
  • 25
    • 62549115236 scopus 로고    scopus 로고
    • PALB2 links BRCA1 and BRCA2 in the DNA-damage response
    • Zhang F, et al. (2009) PALB2 links BRCA1 and BRCA2 in the DNA-damage response. Curr Biol 19:524-529.
    • (2009) Curr Biol , vol.19 , pp. 524-529
    • Zhang, F.1
  • 26
    • 0037666792 scopus 로고    scopus 로고
    • Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation
    • Troussard AA, et al. (2003) Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation. J Biol Chem 278:22374-22378.
    • (2003) J Biol Chem , vol.278 , pp. 22374-22378
    • Troussard, A.A.1
  • 27
    • 0038148536 scopus 로고    scopus 로고
    • Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes
    • Terpstra L, et al. (2003) Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes. J Cell Biol 162:139-148.
    • (2003) J Cell Biol , vol.162 , pp. 139-148
    • Terpstra, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.