Signaling of the ITK (interleukin 2-inducible T cell kinase)-SYK (spleen tyrosine kinase) fusion kinase is dependent on adapter SLP-76 and on the adapter function of the kinases SYK and zap70

Journal of Biological Chemistry

Volumn 288, Issue 10, 2013, Pages 7338-7350

  Hussain, Alamdar ^a,b   Mohammad, Dara K ^a   Gustafsson, Manuela O ^a   Uslu, Merve ^a   Hamasy, Abdulrahman ^a   Nore, Beston F ^a,c   Mohamed, Abdalla J ^a,d   Smith, C I Edvard ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b Department of Electrical Computer Engineering   (Pakistan)

^c Department of Biochemistry   (Iraq)

^d UNIVERSITI BRUNEI DARUSSALAM   (Brunei Darussalam)

Author keywords

[No Author keywords available]

Indexed keywords

FUSION PROTEINS; INTRACELLULAR SIGNALING; SPLEEN TYROSINE KINASE; T-CELL LYMPHOMAS;

AMINO ACIDS; ENZYMES;

CELL SIGNALING;

CD69 ANTIGEN; CELL PROTEIN; GLUTAMIC ACID; HYBRID PROTEIN; INTERLEUKIN 2; INTERLEUKIN 2 INDUCIBLE T CELL KINASE SPLEEN TYROSINE KINASE; ONCOPROTEIN; PHENYLALANINE; PROTEIN KINASE SYK; PROTEIN KINASE ZAP 70; SH2 DOMAIN CONTAINING LEUKOCYTE PROTEIN OF 76; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL ASSAY; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME PHOSPHORYLATION; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SUBSTITUTION; ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; BLOTTING, WESTERN; COS CELLS; FLOW CYTOMETRY; GLUTAMIC ACID; HEK293 CELLS; HUMANS; INTERLEUKIN-2; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; MUTATION; ONCOGENE PROTEINS, FUSION; PHENYLALANINE; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TYROSINE; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 84874915414     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.374967     Document Type: Article

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