TEC family kinases in health and disease - Loss-of-function of BTK and ITK and the gain-of-function fusions ITK-SYK and BTK-SYK

FEBS Journal

Volumn 278, Issue 12, 2011, Pages 2001-2010

  Hussain, Alamdar ^a,b   Yu, Liang ^a,c   Faryal, Rani ^a,b   Mohammad, Dara K ^a   Mohamed, Abdalla J ^a,d   Smith, C I Edvard ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b Department of Electrical Computer Engineering   (Pakistan)

^c NANJING MEDICAL UNIVERSITY   (China)

^d UNIVERSITI BRUNEI DARUSSALAM   (Brunei Darussalam)

Author keywords

AKT; BMX; BTK; ITK; lymphocyte; PH domain; RLK; TEC; TXK; X linked agammaglobulinemia

Indexed keywords

ANTIBIOTIC AGENT; BORTEZOMIB; BRUTON TYROSINE KINASE; BRUTON TYROSINE KINASE PROTEIN KINASE SYK FUSION PROTEIN; HYBRID PROTEIN; IMMUNOGLOBULIN; INTERLEUKIN 2 INDUCIBLE T CELL KINASE; INTERLEUKIN 2 INDUCIBLE T CELL KINASE PROTEIN KINASE SYK FUSION PROTEIN; PROTEASOME INHIBITOR; PROTEIN TYROSINE KINASE; TEC FAMILY KINASE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; BACTERIAL INFECTION; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME STRUCTURE; EPSTEIN BARR VIRUS INFECTION; GAIN OF FUNCTION MUTATION; GENETIC ASSOCIATION; GENOTYPE PHENOTYPE CORRELATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION SENSITIVITY; LOSS OF FUNCTION MUTATION; MISSENSE MUTATION; MOLECULAR PATHOLOGY; MUTATIONAL ANALYSIS; NONHUMAN; NONSENSE MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; REVIEW; RNA INTERFERENCE; SIGNAL TRANSDUCTION; X LINKED AGAMMAGLOBULINEMIA;

AGAMMAGLOBULINEMIA; ANIMALS; ENZYME ACTIVATION; EPSTEIN-BARR VIRUS INFECTIONS; GENETIC ASSOCIATION STUDIES; GENETIC DISEASES, X-LINKED; HIV INFECTIONS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MODELS, MOLECULAR; MUTANT PROTEINS; MUTATION; PROTEIN-TYROSINE KINASES; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

HUMAN HERPESVIRUS 4;

EID: 79958175151     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08134.x     Document Type: Review

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