Ordering a dynamic protein Via a small-molecule stabilizer

Journal of the American Chemical Society

Volumn 135, Issue 9, 2013, Pages 3363-3366

  Wang, Ningkun ^a   Majmudar, Chinmay Y ^a   Pomerantz, William C ^a   Gagnon, Jessica K ^a   Sadowsky, Jack D ^b   Meagher, Jennifer L ^a   Johnson, Taylor K ^a   Stuckey, Jeanne A ^a   Brooks III, Charles L ^a   Wells, James A ^b   Mapp, Anna K ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PARTNERS; CONFORMATIONAL DYNAMICS; CRYSTALLOGRAPHIC CHARACTERIZATION; DYNAMIC PROTEINS; MOLECULAR DYNAMICS SIMULATIONS; RESOLUTION STRUCTURE; STRUCTURAL CHARACTERIZATION; TRANSCRIPTIONAL ACTIVATORS;

CHARACTERIZATION; MOLECULAR DYNAMICS; PROTEINS;

MOLECULES;

GACKIX PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CRYSTALLIZATION; CRYSTALLOGRAPHY; DISULFIDE BOND; HYDROPHOBICITY; MOLECULAR DYNAMICS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN STRUCTURE; TRANSCRIPTION INITIATION;

MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR STRUCTURE; PROTEINS; SMALL MOLECULE LIBRARIES; SURFACE PROPERTIES;

EID: 84874902622     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja3122334     Document Type: Article

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