Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300

Angewandte Chemie - International Edition

Volumn 51, Issue 45, 2012, Pages 11258-11262

  Majmudar, Chinmay Y ^a   Højfeldt, Jonas W ^a   Arevang, Carl J ^a   Pomerantz, William C ^a   Gagnon, Jessica K ^a   Schultz, Pamela J ^a   Cesa, Laura C ^a   Doss, Conor H ^a   Rowe, Steven P ^a   Vásquez, Victor ^a,b   Tamayo Castillo, Giselle ^a,b,c   Cierpicki, Tomasz ^a   Brooks III, Charles L ^a   Sherman, David H ^a   Mapp, Anna K ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b INSTITUTO NACIONAL DE BIODIVERSIDAD   (Costa Rica)

^c UNIVERSIDAD DE COSTA RICA   (Costa Rica)

Author keywords

coactivators; depsides; inhibitors; protein protein interactions; sekikaic acid

Indexed keywords

COACTIVATORS; DEPSIDES; DYNAMIC BINDING; DYNAMIC INTERFACE; HIGH-THROUGHPUT; NATURAL PRODUCTS; PROTEIN-PROTEIN INTERACTIONS;

CATALYSIS; CHEMISTRY; CORROSION INHIBITORS;

PROTEINS;

DEPSIDE; HISTONE ACETYLTRANSFERASE PCAF; LACTONE; LOBARIC ACID; SALICYLIC ACID DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; GENETICS; METABOLISM; MOLECULAR DYNAMICS; PROTEIN TERTIARY STRUCTURE;

DEPSIDES; LACTONES; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; P300-CBP TRANSCRIPTION FACTORS; PROTEIN STRUCTURE, TERTIARY; SALICYLATES;

EID: 84868104231     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201206815     Document Type: Article

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