Eugenia uniflora L. essential oil as a potential anti-leishmania agent: Effects on leishmania amazonensis and possible mechanisms of action

Evidence-based Complementary and Alternative Medicine

Volumn 2013, Issue , 2013, Pages

  Rodrigues, Klinger Antonio Da Franca ^a   Amorim, Layane Valéria ^a   Oliveira, Jamylla Mirck Guerra De ^a   Dias, Clarice Noleto ^b   Moraes, Denise Fernandes Coutinho ^b   Andrade, Eloisa Helena De Aguiar ^c   Maia, Jose Guilherme Soares ^c   Carneiro, Sabrina Maria Portela ^a   Carvalho, Fernando Aécio De Amorim ^a  

^a FEDERAL UNIVERSITY OF PIAUÍ   (Brazil)

^b FEDERAL UNIVERSITY OF MARANHÃO   (Brazil)

^c FEDERAL UNIVERSITY OF PARÁ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

AROMADENDRENE; CARYOPHYLLENE; CARYOPHYLLENE OXIDE; CUMINALDEHYDE; DELTA CADINENE; ESSENTIAL OIL; EUDESMANE DERIVATIVE; EUGENIA UNIFLORA EXTRACT; GAMMA CADINENE; GERMACRENE D; HUMULENE; LIMONENE; LINALOOL; MYRCENE; NITRIC OXIDE; SESQUITERPENE; SPATHULENOL; TERPENOID; VIRIDIFLOROL;

AMASTIGOTE; ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG SCREENING; DRUG TOLERABILITY; EUGENIA; EUGENIA UNIFLORA; HEMOLYSIS; IC 50; LEISHMANIA; MACROPHAGE; MASS FRAGMENTOGRAPHY; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL;

EID: 84874823373     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2013/279726     Document Type: Article

References (60)

1. Kaur S., Sachdeva H., Dhuria S., Sharma M., Kaur T., Antileishmanial effect of cisplatin against murine visceral leishmaniasis. Parasitology International 2010 59 1 62 69 2-s2.0-76349086675 10.1016/j.parint.2009.10.006
2. Azzouz S., Maache M., Garcia R. G., Osuna A., Leishmanicidal activity of edelfosine, miltefosine and ilmofosine. Basic and Clinical Pharmacology and Toxicology 2005 96 1 60 65 2-s2.0-13844318808 10.1111/j.1742-7843.2005. pto960109.x (Pubitemid 40260848)
3. Patza J. A., Graczykb T. K., Gellera N., Vittorc A. Y., Effects of environmental change on emerging parasitic diseases. International Journal of Parasitology 2000 30 12-13 1295 1304 10.1016/S0020-7519(00)00133-8
4. Alizadeh B. H., Foroumadi A., Ardestani S. K., Poorrajab F., Shafiee A., Leishmanicidal evaluation of novel synthetic chromenes. Archiv der Pharmazie 2008 341 12 787 793 2-s2.0-57049182630 10.1002/ardp.200800128
5. Ashford R. W., The leishmaniases as emerging and reemerging zoonoses. International Journal for Parasitology 2000 30 12-13 1269 1281 2-s2.0-0033709808 10.1016/S0020-7519(00)00136-3
6. Rosa M. S. S., Mendonça-Filho R. R., Bizzo H. R., Rodrigues I. A., Soares R. M., Souto-Padrón T., Alviano C. S., Lopes A. H. C. S., Antileishmanial activity of a linalool-rich essential oil from Croton cajucara. Antimicrobial Agents Chemotherapy 2003 47 6 1895 1901 (Pubitemid 36637811)
7. Ueda-Nakamura T., Mendonça-Filho R. R., Morgado-Díaz J. A., Maza P. K., Filho B. P. D., Cortez D. A. G., Alviano D. S., Rosa M. S. S., Lopes A. H. C. S., Alviano C. S., Nakamura C. V., Antileishmanial activity of eugenol-rich essential oil from Ocimum gratissimum. Parasitology International 2006 55 2 55 59
8. Santos A. O., Ueda-Nakamura T., Dias Filho B. P., Veiga Junior V. F., Pinto A. C., Nakamura C. V., Effect of Brazilian copaiba oils on Leishmania amazonensis. Journal of Ethnopharmacology 2008 120 2 204 208 2-s2.0-55349144128 10.1016/j.jep.2008.08.007
9. Monzote L., Montalvo A. M., Almanonni S., Scull R., Miranda M., Abreu J., Activity of the essential oil from Chenopodium ambrosioides grown in Cuba against Leishmania amazonensis. Chemotherapy 2006 52 3 130 136 2-s2.0-33646803835 10.1159/000092858 (Pubitemid 43760310)
10. Machado M., Pires P., Dinis A. M., Santos-Rosa M., Alves V., Salgueiro L., Cavaleiro C., Sousa M. C., Monoterpenic aldehydes as potential anti- Leishmania agents: activity of Cymbopogon citratus and citral on L. infantum, L. tropica and L. major. Experimental Parasitology 2012 130 3 223 231 10.1016/j.exppara.2011.12.012
11. Santin M. R., Dos Santos A. O., Nakamura C. V., Dias Filho B. P., Ferreira I. C. P., Ueda-Nakamura T., In vitro activity of the essential oil of Cymbopogon citratus and its major component (citral) on Leishmania amazonensis. Parasitology Research 2009 105 6 1489 1496 2-s2.0-70350222212 10.1007/s00436-009-1578-7
12. Oliveira V. C. S., Moura D. M. S., Lopes J. A. D., De Andrade P. P., Da Silva N. H., Figueiredo R. C. B. Q., Effects of essential oils from Cymbopogon citratus (DC) Stapf., Lippia sidoides Cham., and Ocimum gratissimum L. on growth and ultrastructure of Leishmania chagasi promastigotes. Parasitology Research 2009 104 5 1053 1059 2-s2.0-62949219687 10.1007/s00436-008-1288-6
13. Consolini A. E., Sarubbio M. G., Pharmacological effects of Eugenia uniflora (Myrtaceae) aqueous crude extract on rat's heart. Journal of Ethnopharmacology 2002 81 1 57 63 2-s2.0-0036000244 10.1016/S0378-8741(02)00039- 9 (Pubitemid 34518469)
14. Alice C. B., Vargas V. M. F., Silva G. A. A. B., De Siqueira N. C. S., Schapoval Gleye E. E. S. J., Henriques J. A. P., Henriques A. T., Screening of plants used in south Brazilian folk medicine. Journal of Ethnopharmacology 1991 35 2 165 171 2-s2.0-0026010420
15. Weyerstahl P., Marschall-Weyerstahl H., Christiansen C., Oguntimein B. O., Adeoye A. O., Volatile constituents of Eugenia uniflora leaf oil. Planta medica 1988 54 6 546 549 2-s2.0-0024257111
16. Victoria F. N., Lenardão E. J., Savegnago L., Perin G., Jacob R. G., Alves D., da Silva W. P., da Mota A. S., Nascente P. S., Essential oil of the leaves of Eugenia uniflora L.: antioxidant and antimicrobial properties. Food and Chemical Toxicology 2012 50 8 2668 2674 10.1016/j.fct.2012.05.002
17. Consolini A. E., Baldini O. A. N., Amat A. G., Pharmacological basis for the empirical use of Eugenia uniflora L. (Myrtaceae) as antihypertensive. Journal of Ethnopharmacology 1999 66 1 33 39 2-s2.0-0033008530 10.1016/S0378-8741(98)00194-9 (Pubitemid 29305411)
18. Ogunwande I. A., Olawore N. O., Ekundayo O., Walker T. M., Schmidt J. M., Setzer W. N., Studies on the essential oils composition, antibacterial and cytotoxicity of Eugenia uniflora L. International Journal of Aromatherapy 2005 15 3 147 152 2-s2.0-24644489723 10.1016/j.ijat.2005.07.004 (Pubitemid 41265810)
19. Amorim A. C. L., Lima C. K. F., Hovell A. M. C., Miranda A. L. P., Rezende C. M., Antinociceptive and hypothermic evaluation of the leaf essential oil and isolated terpenoids from Eugenia uniflora L. (Brazilian Pitanga). Phytomedicine 2009 16 10 923 928 2-s2.0-69849105020 10.1016/j.phymed.2009.03.009
20. Costa D. P., Filho E. G. A., Silva L. M. A., Santos S. C., Passos X. S., Do Rosário M. M., Seraphin J. C., Ferri P. H., Influence of fruit biotypes on the chemical composition and antifungal activity of the essential oils of Eugenia uniflora leaves. Journal of the Brazilian Chemical Society 2010 21 5 851 858 2-s2.0-77953060624
21. Ibikunle G. F., Adebajo A. C., Famuyiwa F. G., Aladesanmi A. J., Adewunmi C. O., In-vitro evaluation of anti-trichomonal activities of Eugenia uniflora leaf. African Journal of Traditional, Complementary and Alternative Medicines 2011 8 2 170 176 2-s2.0-79960317421
22. Santos K. K., Tintino S. R., Souza C. E., Braga M. F., Guedes G. M., Rolón M., Vega C., De Arias A. R., Menezes J. G. Costam I. R., Coutinho H. D., Anti- Trypanosoma cruzi and cytotoxic activities of Eugenia uniflora L. Experimental Parasitology 2012 131 1 130 132 10.1016/j.exppara.2012.02.019
23. NIST 05, Mass Spectral Library (NIST/EPA/NIH) 2005 Gaithersburg, Md, USA National Institute of Standards and Technology
24. Adams R. P., Identification of Essential Oil Components By Gas Chromatography/Mass Spectrometry 2007 4th Carol Stream, Ill, USA Allured
25. Carneiro S. M. P., Carvalho F. A. A., Santana L. C. L. R., Sousa A. P. L., Chaves M. H., The cytotoxic and antileishmanial activity of extracts and fractions of leaves and fruits of Azadirachta indica (A Juss.). Biological Research 2012 45 2 111 116 10.4067/S0716-97602012000200002
26. de Medeiros M. D. G. F., da Silva A. C., Citó A. M. D. G. L., Borges A. R., de Lima S. G., Lopes J. A. D., Figueiredo R. C. B. Q., In vitro antileishmanial activity and cytotoxicity of essential oil from Lippia sidoides Cham. Parasitology International 2011 60 3 237 241 2-s2.0-79959516674 10.1016/j.parint.2011.03.004
27. Löfgren S. E., Miletti L. C., Steindel M., Bachère E., Barracco M. A., Trypanocidal and leishmanicidal activities of different antimicrobial peptides (AMPs) isolated from aquatic animals. Experimental Parasitology 2008 118 2 197 202 2-s2.0-37449023691 10.1016/j.exppara.2007.07.011
28. Grando F. C. C., Felício C. A., Twardowschy A., Paula F. M., Batista V. G., Fernandes L. C., Curi R., Nishiyama A., Modulation of peritoneal macrophage activity by the saturation state of the fatty acid moiety of phosphatidylcholine. Brazilian Journal of Medical and Biological Research 2009 42 7 599 605 2-s2.0-68649113353
29. Iwu M. M., Jackson J. E., Schuster B. G., Medicinal plants in the fight against leishmaniasis. Parasitology Today 1994 10 2 65 68 2-s2.0-0028008676 10.1016/0169-4758(94)90398-0 (Pubitemid 24052919)
30. Rocha L. G., Almeida J. R. G. S., Macêdo R. O., Barbosa-Filho J. M., A review of natural products with antileishmanial activity. Phytomedicine 2005 12 6-7 514 535 2-s2.0-19944424798 10.1016/j.phymed.2003.10.006 (Pubitemid 40755130)
31. De Morais S. M., Craveiro A. A., Machado M. I. L., Alencar J. W., Matos F. J. A., Volatile constituents of Eugenia uniflora leaf oil from northeastern Brazil. Journal of Essential Oil Research 1996 8 4 449 451 2-s2.0-0030195314 (Pubitemid 126478815)
32. Maia J. G. S., Andrade E. H. A., Da Silva M. H. L., Zoghbi M. G. B., A new chemotype of Eugenia uniflora L. from North Brazil. Journal of Essential Oil Research 1999 11 6 727 729 2-s2.0-0000966877 (Pubitemid 129677019)
33. Lago J. H. G., Souza E. D., Mariane B., Pascon R., Vallim M. A., Martins R. C. C., Baroli A. A., Carvalho B. A., Soares M. G., dos Santos R. T., Sartorelli P., Chemical and biological evaluation of essential oils from two species of myrtaceae-Eugenia uniflora L. and Plinia trunciflora (O. Berg) Kausel. Molecules 2011 16 12 9826 9837
34. Chang R., de Morais S. A. L., Napolitano D. R., Duarte K. C., Guzman V. B., do Nascimento E. A., A new approach for quantifying furanodiene and curzerene. A case study on the essential oils of Eugenia uniflora (pitangueira) leaves. Brazilian Journal of Pharmacognosy 2011 21 3 392 396 2-s2.0-79960612638 10.1590/S0102-695X2011005000042
35. Adio A. M., Germacrenes A-E and related compounds: thermal, photochemical and acid induced transannular cyclizations. Tetrahedron 2009 65 8 1533 1552 2-s2.0-58249126738 10.1016/j.tet.2008.11.050
36. Costa D. P., Santos S. C., Seraphin J. C., Ferri P. H., Seasonal variability of essential oils of Eugenia uniflora leaves. Journal of the Brazilian Chemical Society 2009 20 7 1287 1293 2-s2.0-76149134045
37. Henriques A. T., Sobral M. E., Caudaro A. D., Schapoval E. E. S., Bassani V. L., Lamaty G., Aromatic plants from Brazil II. The chemical composition of some Eugenia essential oils. Journal of Essential Oil Research 1993 5 5 501 505 10.1080/10412905.1993.9698270
38. Teixeira B., Marques A., Ramos C., Batista I., Serrano C., Matos O., Neng N. R., Nogueira J. M. F., Nunes M. L., European pennyroyal (Mentha pulegium) from portugal: chemical composition of essential oil and antioxidant and antimicrobial properties of extracts and essential oil. Industrial Crops and Products 2012 36 1 81 87 10.1016/j.indcrop.2011.08.011
39. Arruda D. C., D'Alexandri F. L., Katzin A. M., Uliana S. R. B., Antileishmanial activity of the terpene nerolidol. Antimicrobial Agents and Chemotherapy 2005 49 5 1679 1687 2-s2.0-18244393165 10.1128/AAC.49.5.1679-1687. 2005 (Pubitemid 40631574)
40. Di Pasqua R., Betts G., Hoskins N., Edwards M., Ercolini D., Mauriello G., Membrane toxicity of antimicrobial compounds from essential oils. Journal of Agricultural and Food Chemistry 2007 55 12 4863 4870 2-s2.0-34250712749 10.1021/jf0636465 (Pubitemid 46960917)
41. Tariku Y., Hymete A., Hailu A., Rohloff J., Essential-oil composition, antileishmanial, and toxicity study of Artemisia abyssinica and Satureja punctata ssp. punctata from Ethiopia. Chemistry and Biodiversity 2010 7 4 1009 1018 2-s2.0-77951161718 10.1002/cbdv.200900375
42. Armstrong J. S., Mitochondrial membrane permeabilization: the sine qua non for cell death. BioEssays 2006 28 3 253 260 2-s2.0-33645420460 10.1002/bies.20370
43. Silva A. L., Adade C. M., Shoyama F. M., Neto C. P., Padrón T. S., De Almeida M. V., Rezende C. A., Silva C. V., Souza M. A., In vitro leishmanicidal activity of N -dodecyl-1, 2-ethanediamine. Biomedicine and Pharmacotherapy 2012 66 3 180 186
44. Purkait B., Kumar A., Nandi N., Sardar A. H., Das S., Kumar S., Pandey K., Ravidas V., Kumar M., De T., Singh D., Das P., Mechanism of amphotericin B resistance in clinical isolates of Leishmania donovani. Antimicrobial Agents and Chemotherapy 2012 56 2 1031 1141 10.1128/AAC.00030-11
45. Vermeersch M., Da Luz R. I., Toté K., Timmermans J. P., Cos P., Maes L., In vitro susceptibilities of Leishmania donovani promastigote and amastigote stages to antileishmanial reference drugs: practical relevance of stage-specific differences. Antimicrobial Agents and Chemotherapy 2009 53 9 3855 3859 2-s2.0-70349131162 10.1128/AAC.00548-09
46. Di Giorgio C., Delmas F., Akhmedjanova V., Ollivier E., Bessonova I., Riad E., Timon-David P., In vitro antileishmanial activity of diphyllin isolated from Haplophyllum bucharicum. Planta Medica 2005 71 4 366 369 2-s2.0-18744407303 10.1055/s-2005-864106 (Pubitemid 40676465)
47. Martinez-Rojano H., Mancilla-Ramirez J., Quiñonez-Diaz L., Galindo-Sevilla N., Activity of hydroxyurea against Leishmania mexicana. Antimicrobial Agents and Chemotherapy 2008 52 10 3642 3647 2-s2.0-54049094432 10.1128/AAC.00124-08
48. Tariku Y., Hymete A., Hailu A., Rohloff J., Essential-oil composition, antileishmanial, and toxicity study of Artemisia abyssinica and Satureja punctata ssp. punctata from Ethiopia. Chemistry and Biodiversity 2010 7 4 1009 1018 2-s2.0-77951161718 10.1002/cbdv.200900375
49. Klimp A. H., De Vries E. G. E., Scherphof G. L., Daemen T., A potential role of macrophage activation in the treatment of cancer. Critical Reviews in Oncology/Hematology 2002 44 2 143 161 2-s2.0-12244260787 10.1016/S1040-8428(01) 00203-7 (Pubitemid 36159043)
50. Piemonte M. R., Buchi D. F., Analysis of IL-12, IFN- γ and TNF- α production, a5b1 integrins and actin filaments distribution in peritoneal mouse macrophages treated with homeopathic medicament. Journal of Submicroscopic Cytology and Pathology 2002 33 1 255 263
51. Niedergang F., Chavrier P., Signaling and membrane dynamics during phagocytosis: Many roads lead to the phagos(R)ome. Current Opinion in Cell Biology 2004 16 4 422 428 2-s2.0-3142514390 10.1016/j.ceb.2004.06.006 (Pubitemid 38903149)
52. Lee W. L., Harrison R. E., Grinstein S., Phagocytosis by neutrophils. Microbes and Infection 2003 5 14 1299 1306 10.1016/j.micinf.2003.09.014 (Pubitemid 37410243)
53. Green S. J., Meltzer M. S., Hibbs J. B., Nacy C. A., Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism. Journal of Immunology 1990 144 1 278 283 2-s2.0-0025191159 (Pubitemid 20030489)
54. Osorio E., Arango G. J., Jiménez N., Alzate F., Ruiz G., Gutiérrez D., Paco M. A., Giménez A., Robledo S., Antiprotozoal and cytotoxic activities in vitro of Colombian Annonaceae. Journal of Ethnopharmacology 2007 111 3 630 635 10.1016/j.jep.2007.01.015 (Pubitemid 46617110)
55. Kamhawi S., Phlebotomine sand flies and Leishmania parasites: friends or foes? Trends in Parasitology 2006 22 9 439 445 2-s2.0-33746825106 10.1016/j.pt.2006.06.012 (Pubitemid 44176407)
56. Tripathi P., Singh V., Naik S., Immune response to leishmania: paradox rather than paradigm. FEMS Immunology and Medical Microbiology 2007 51 2 229 242 2-s2.0-35148817368 10.1111/j.1574-695X.2007.00311.x (Pubitemid 47547509)
57. Costa-Lotufo L. V., Cunha G. M. A., Farias P. A. M., Viana G. S. B., Cunha K. M. A., Pessoa C., Moraes M. O., Silveira E. R., Gramosa N. V., Rao V. S. N., The cytotoxic and embryotoxic effects of kaurenoic acid, a diterpene isolated from Copaifera langsdorffii oleo-resin. Toxicon 2002 40 8 1231 1234 2-s2.0-0035993557 10.1016/S0041-0101(02)00128-9
58. Aparicio R. M., García-Celma M. J., Pilar Vinardell M., Mitjans M., In vitro studies of the hemolytic activity of microemulsions in human erythrocytes. Journal of Pharmaceutical and Biomedical Analysis 2005 39 5 1063 1067 2-s2.0-26644472440 10.1016/j.jpba.2005.06.013 (Pubitemid 41441739)
59. Lexis L. A., Fassett R. G., Coombes J. S., α -tocopherol and α -lipoic acid enhance the erythrocyte antioxidant defence in cyclosporine A-treated rats. Basic and Clinical Pharmacology and Toxicology 2006 98 1 68 73 2-s2.0-33645099476 10.1111/j.1742-7843.2006.pto-222.x
60. Muñoz-Castañeda J. R., Muntané J., Muñoz M. C., Bujalance I., Montilla P., Tunez I., Estradiol and catecholestrogens protect against adriamycininduced oxidative stress in erythrocytes of ovariectomized rats. Toxicology Letters 2006 160 3 196 203 10.1016/j.toxlet.2005.07.003 (Pubitemid 41628106)