-
1
-
-
1242270521
-
Ultrastructural and cytochemical identification of megasome in Leishmania (Leishmania) chagasi
-
Alberio, S. O., S. S. Dias, F. P. Faria, R. A. Mortara, C. L. Barbieri, and E. F. Haapalainen. 2004. Ultrastructural and cytochemical identification of megasome in Leishmania (Leishmania) chagasi. Parasitol. Res. 92:246-254.
-
(2004)
Parasitol. Res.
, vol.92
, pp. 246-254
-
-
Alberio, S.O.1
Dias, S.S.2
Faria, F.P.3
Mortara, R.A.4
Barbieri, C.L.5
Haapalainen, E.F.6
-
2
-
-
33847219040
-
Molecular mechanisms of antimony resistance in Leishmania
-
Ashutosh, S. Sundar, and N. Goyal. 2007. Molecular mechanisms of antimony resistance in Leishmania. J. Med. Microbiol. 56:143-153.
-
(2007)
J. Med. Microbiol.
, vol.56
, pp. 143-153
-
-
Ashutosh1
Sundar, S.2
Goyal, N.3
-
3
-
-
27744451508
-
Clinical status of agents being developed for leishmaniasis
-
Berman, J. 2005. Clinical status of agents being developed for leishmaniasis. Expert Opin. Investig. Drugs 14:1337-1346.
-
(2005)
Expert Opin. Investig. Drugs
, vol.14
, pp. 1337-1346
-
-
Berman, J.1
-
4
-
-
0030892248
-
An axenic amastigote system for drug screening
-
Callahan, H. L., A. C. Portal, R. Devereaux, and M. Grogl. 1997. An axenic amastigote system for drug screening. Antimicrob. Agents Chemother. 41:818-822.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 818-822
-
-
Callahan, H.L.1
Portal, A.C.2
Devereaux, R.3
Grogl, M.4
-
5
-
-
35548987998
-
Visceral leishmaniasis: What are the needs for diagnosis, treatment and control?
-
Chappuis, F., S. Sundar, A. Hailu, H. Ghalib, S. Rijal, R. W. Peeling, J. Alvar, and M. Boelaert. 2007. Visceral leishmaniasis: what are the needs for diagnosis, treatment and control? Nat. Rev. Microbiol. 5:873-882.
-
(2007)
Nat. Rev. Microbiol.
, vol.5
, pp. 873-882
-
-
Chappuis, F.1
Sundar, S.2
Hailu, A.3
Ghalib, H.4
Rijal, S.5
Peeling, R.W.6
Alvar, J.7
Boelaert, M.8
-
6
-
-
0034771454
-
Monitoring drug resistance in leishmaniasis
-
Croft, S. L. 2001. Monitoring drug resistance in leishmaniasis. Trop. Med. Int. Health 6:899-905.
-
(2001)
Trop. Med. Int. Health
, vol.6
, pp. 899-905
-
-
Croft, S.L.1
-
8
-
-
0017713461
-
New culture medium for maintenance of tsetse tissues and growth of trypanosomatids
-
Cunningham, I. 1977. New culture medium for maintenance of tsetse tissues and growth of trypanosomatids. J. Protozool. 24:325-329. (Pubitemid 8156212)
-
(1977)
Journal of Protozoology
, vol.24
, Issue.2
, pp. 325-329
-
-
Cunningham, I.1
-
9
-
-
1242294372
-
Generation of Leishmania donovani axenic amastigotes: Their growth and biological characteristics
-
Debrabant, A., M. B. Joshi, P. F. P. Pimenta, and D. M. Dwyer. 2004. Generation of Leishmania donovani axenic amastigotes: their growth and biological characteristics. Int. J. Parasitol. 34:205-217.
-
(2004)
Int. J. Parasitol.
, vol.34
, pp. 205-217
-
-
Debrabant, A.1
Joshi, M.B.2
Pimenta, P.F.P.3
Dwyer, D.M.4
-
10
-
-
0036667469
-
In vitro activity of Triclisia patens and some bisbenzylisoquinoline alkaloids against Leishmania donovani and Trypanosoma brucei brucei
-
del Rayo Camacho, M., J. D. Phillipson, S. L. Croft, P. Rock, S. J. Marshall, and P. L. Schiff. 2002. In vitro activity of Triclisia patens and some bisbenzylisoquinoline alkaloids against Leishmania donovani and Trypanosoma brucei brucei. Phytother. Res. 16:432-436.
-
(2002)
Phytother. Res.
, vol.16
, pp. 432-436
-
-
Del Rayo Camacho, M.1
Phillipson, J.D.2
Croft, S.L.3
Rock, P.4
Marshall, S.J.5
Schiff, P.L.6
-
11
-
-
70349137515
-
Annual report, 2007-2008
-
DNDi, Geneva, Switzerland
-
Drugs for Neglected Diseases Initiative. 2008. Annual report, 2007-2008. DNDi, Geneva, Switzerland.
-
(2008)
Drugs for Neglected Diseases Initiative
-
-
-
12
-
-
21644432930
-
Refractoriness to the treatment of sodium stibogluconate in Indian kala-azar field isolates persist in in vitro and in vivo experimental models
-
DOI 10.1007/s00436-005-1339-1
-
Dube, A., N. Singh, S. Sundar, and N. Singh. 2005. Refractoriness to the treatment of sodium stibogluconate in Indian kala-azar field isolates persists in in vitro and in vivo experimental models. Parasitol. Res. 96:216-223. (Pubitemid 40933669)
-
(2005)
Parasitology Research
, vol.96
, Issue.4
, pp. 216-223
-
-
Dube, A.1
Singh, N.2
Sundar, S.3
Singh, N.4
-
13
-
-
0032990769
-
Stage-specific activity of pentavalent antimony against Leishmania donovani axenic amastigotes
-
Ephros, M., A. Bitnun, P. Shaked, E. Waldman, and D. Zilberstein. 1999. Stage-specific activity of pentavalent antimony against Leishmania donovani axenic amastigotes. Antimicrob. Agents Chemother. 43:278-282.
-
(1999)
Antimicrob. Agents Chemother.
, vol.43
, pp. 278-282
-
-
Ephros, M.1
Bitnun, A.2
Shaked, P.3
Waldman, E.4
Zilberstein, D.5
-
14
-
-
0036150927
-
Sensitivities of Leishmania species to hexadecylphosphocholine (miltefosine), ET-18-OCH(3) (edelfosine) and amphotericin B
-
Escobar, P., S. Matu, C. Marques, and S. L. Croft. 2002. Sensitivities of Leishmania species to hexadecylphosphocholine (miltefosine), ET-18-OCH(3) (edelfosine) and amphotericin B. Acta Trop. 81:151-157.
-
(2002)
Acta Trop.
, vol.81
, pp. 151-157
-
-
Escobar, P.1
Matu, S.2
Marques, C.3
Croft, S.L.4
-
15
-
-
2442515288
-
In vitro assays for evaluation of drug activity against Leishmania spp
-
Fumarola, L., R. Spinelli, and O. Brandonisio. 2004. In vitro assays for evaluation of drug activity against Leishmania spp. Res. Microbiol. 155:224-230.
-
(2004)
Res. Microbiol.
, vol.155
, pp. 224-230
-
-
Fumarola, L.1
Spinelli, R.2
Brandonisio, O.3
-
16
-
-
0035005951
-
In vitro cultivation and characterization of axenic amastigotes of Leishmania
-
DOI 10.1016/S1471-4922(00)01811-0, PII S1471492200018110
-
Gupta, N., N. Goyal, and A. K. Rastogi. 2001. In vitro cultivation and characterization of axenic amastigotes of Leishmania. Trends Parasitol. 17:150-153. (Pubitemid 32422185)
-
(2001)
Trends in Parasitology
, vol.17
, Issue.3
, pp. 150-153
-
-
Gupta, N.1
Goyal, N.2
Rastogi, A.K.3
-
17
-
-
33644828887
-
Expression profiling by whole-genome interspecies microarray hybridization reveals differential gene expression in procyclic promastigotes, lesion-derived amastigotes, and axenic amastigotes in Leishmania mexicana
-
Holzer, T. R., W. R. McMaster, and J. D. Forney. 2006. Expression profiling by whole-genome interspecies microarray hybridization reveals differential gene expression in procyclic promastigotes, lesion-derived amastigotes, and axenic amastigotes in Leishmania mexicana. Mol. Biochem. Parasitol. 146:198-218.
-
(2006)
Mol. Biochem. Parasitol.
, vol.146
, pp. 198-218
-
-
Holzer, T.R.1
McMaster, W.R.2
Forney, J.D.3
-
18
-
-
59749105928
-
In vitro susceptibility of field isolates of Leishmania donovani to miltefosine and amphotericin B: Correlation with sodium antimony gluconate susceptibility and implications for treatment in areas of endemicity
-
Kumar, D., A. Kulshrestha, R. Singh, and P. Salotra. 2009. In vitro susceptibility of field isolates of Leishmania donovani to miltefosine and amphotericin B: correlation with sodium antimony gluconate susceptibility and implications for treatment in areas of endemicity. Antimicrob. Agents Chemother. 53:835-838.
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 835-838
-
-
Kumar, D.1
Kulshrestha, A.2
Singh, R.3
Salotra, P.4
-
19
-
-
0347992035
-
In Vitro and in Vivo Activities of a Triterpenoid Saponin Extract (PX-6518) from the Plant Maesa balansae against Visceral Leishmania Species
-
DOI 10.1128/AAC.48.1.130-136.2004
-
Maes, L., D. Vanden Berghe, N. Germonprez, L. Quirijnen, P. Cos, N. De Kimpe, and L. Van Puyvelde. 2004. In vitro and in vivo activities of a triterpenoid saponin extract (PX-6518) from the plant Maesa balansae against visceral Leishmania species. Antimicrob. Agents Chemother. 48:130-136. (Pubitemid 38040188)
-
(2004)
Antimicrobial Agents and Chemotherapy
, vol.48
, Issue.1
, pp. 130-136
-
-
Maes, L.1
Vanden Berghe, D.2
Germonprez, N.3
Quirijnen, L.4
Cos, P.5
De Kimpe, N.6
Van Puyvelde, L.7
-
20
-
-
0031893745
-
Mechanism of amphotericin B resistance in Leishmania donovani promastigotes
-
Mbongo, N., P. M. Loiseau, M. A. Billion, and M. Robert-Gero. 1998. Mechanism of amphotericin B resistance in Leishmania donovani promastigotes. Antimicrob. Agents Chemother. 42:352-357.
-
(1998)
Antimicrob. Agents Chemother.
, vol.42
, pp. 352-357
-
-
Mbongo, N.1
Loiseau, P.M.2
Billion, M.A.3
Robert-Gero, M.4
-
21
-
-
0033991437
-
A simple colorimetric method to screen drug cytotoxicity against Leishmania using the dye Alamar Blue
-
Mikus, J., and D. Steverding. 2000. A simple colorimetric method to screen drug cytotoxicity against Leishmania using the dye Alamar Blue. Parasitol. Int. 48:265-269.
-
(2000)
Parasitol. Int.
, vol.48
, pp. 265-269
-
-
Mikus, J.1
Steverding, D.2
-
22
-
-
33646456171
-
Sodium antimony gluconate induces generation of reactive oxygen species and nitric oxide via phosphoinositide 3-kinase and mitogen-activated protein kinase activation in Leishmania donovani-infected macrophages
-
Mookerjee Basu, J., A. Mookerjee, P. Sen, S. Bhaumik, P. Sen, S. Banerjee, K. Naskar, S. K. Choudhuri, B. Saha, S. Raha, and S. Roy. 2006. Sodium antimony gluconate induces generation of reactive oxygen species and nitric oxide via phosphoinositide 3-kinase and mitogen-activated protein kinase activation in Leishmania donovani-infected macrophages. Antimicrob. Agents Chemother. 50:1788-1797.
-
(2006)
Antimicrob. Agents Chemother.
, vol.50
, pp. 1788-1797
-
-
Mookerjee Basu, J.1
Mookerjee, A.2
Sen, P.3
Bhaumik, S.4
Sen, P.5
Banerjee, S.6
Naskar, K.7
Choudhuri, S.K.8
Saha, B.9
Raha, S.10
Roy, S.11
-
23
-
-
40649091062
-
Vaccines for leishmaniasis in the fore coming 25 years
-
Palatnik-de-Sousa, C. B. 2008. Vaccines for leishmaniasis in the fore coming 25 years. Vaccine 26:1709-1724.
-
(2008)
Vaccine
, vol.26
, pp. 1709-1724
-
-
Palatnik-de-Sousa, C.B.1
-
24
-
-
0027563564
-
Developmental life cycle of Leishmania - Cultivation and characterization of cultured extracellular amastigotes
-
Pan, A. A., S. M. Duboise, S. Eperon, L. Rivas, V. Hodgkinson, Y. Traub- Cseko, and D. McMahon-Pratt. 1993. Developmental life cycle of Leishmania - cultivation and characterization of cultured extracellular amastigotes. J. Eukaryot. Microbiol. 40:213-223.
-
(1993)
J. Eukaryot. Microbiol.
, vol.40
, pp. 213-223
-
-
Pan, A.A.1
Duboise, S.M.2
Eperon, S.3
Rivas, L.4
Hodgkinson, V.5
Traub- Cseko, Y.6
McMahon-Pratt, D.7
-
25
-
-
33745253122
-
Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use
-
Pérez-Victoria, F. J., M. P. Sánchez-Cañete, K. Seifert, S. L. Croft, S. Sundar, S. Castanys, and F. Gamarro. 2006. Mechanisms of experimental resistance of Leishmania to miltefosine: implications for clinical use. Drug Resist. Updat. 9:26-39.
-
(2006)
Drug Resist. Updat.
, vol.9
, pp. 26-39
-
-
Pérez-Victoria, F.J.1
Sánchez-Cañete, M.P.2
Seifert, K.3
Croft, S.L.4
Sundar, S.5
Castanys, S.6
Gamarro, F.7
-
26
-
-
34247118212
-
Miltefosine affects lipid metabolism in Leishmania donovani promastigotes
-
Rakotomanga, M., S. Blanc, K. Gaudin, P. Chaminade, and P. M. Loiseau. 2007. Miltefosine affects lipid metabolism in Leishmania donovani promastigotes. Antimicrob. Agents Chemother. 51:1425-1430.
-
(2007)
Antimicrob. Agents Chemother.
, vol.51
, pp. 1425-1430
-
-
Rakotomanga, M.1
Blanc, S.2
Gaudin, K.3
Chaminade, P.4
Loiseau, P.M.5
-
27
-
-
4444244846
-
Treatment of visceral leishmaniasis in south-eastern Nepal: Decreasing efficacy of sodium stibogluconate and need for a policy to limit further decline
-
Rijal, S., F. Chappuis, R. Singh, P. A. Bovier, P. Acharya, B. M. Karki, M. L. Das, P. Desjeux, L. Loutan, and S. Koirala. 2003. Treatment of visceral leishmaniasis in south-eastern Nepal: decreasing efficacy of sodium stibogluconate and need for a policy to limit further decline. Trans. R. Soc. Trop. Med. Hyg. 97:350-354.
-
(2003)
Trans. R. Soc. Trop. Med. Hyg.
, vol.97
, pp. 350-354
-
-
Rijal, S.1
Chappuis, F.2
Singh, R.3
Bovier, P.A.4
Acharya, P.5
Karki, B.M.6
Das, M.L.7
Desjeux, P.8
Loutan, L.9
Koirala, S.10
-
28
-
-
0029031644
-
In vitro antileishmanial properties of tri- and pentavalent antimonial preparations
-
Roberts, W. L., J. D. Berman, and P. M. Rainey. 1995. In vitro antileishmanial properties of tri- and pentavalent antimonial preparations. Antimicrob. Agents Chemother. 39:1234-1239.
-
(1995)
Antimicrob. Agents Chemother.
, vol.39
, pp. 1234-1239
-
-
Roberts, W.L.1
Berman, J.D.2
Rainey, P.M.3
-
29
-
-
70349121268
-
Activity of current anti-leishmanial drugs in in vitro macrophage-amastigote model is dependent on the host macrophage, poster 398
-
Seifert, K., P. Escobar, and S. Croft. 2009. Activity of current anti-leishmanial drugs in in vitro macrophage-amastigote model is dependent on the host macrophage, poster 398. Fourth World Cong. Leishmaniasis, Lucknow, India, 3 to 7 February 2009.
-
(2009)
Fourth World Cong. Leishmaniasis, Lucknow, India, 3 to 7 February 2009
-
-
Seifert, K.1
Escobar, P.2
Croft, S.3
-
30
-
-
34547337720
-
Inactivation of the miltefosine transporter, LdMT, causes miltefosine resistance that is conferred to the amastigote stage of Leishmania donovani and persists in vivo
-
Seifert, K., F. J. Pérez-Victoria, M. Stettler, M. P. Sánchez-Cañete, S. Castanys, F. Gamarro, and S. L. Croft. 2007. Inactivation of the miltefosine transporter, LdMT, causes miltefosine resistance that is conferred to the amastigote stage of Leishmania donovani and persists in vivo. Int. J. Antimicrob. Agents 30:229-235.
-
(2007)
Int. J. Antimicrob. Agents
, vol.30
, pp. 229-235
-
-
Seifert, K.1
Pérez-Victoria, F.J.2
Stettler, M.3
Sánchez- Cañete, M.P.4
Castanys, S.5
Gamarro, F.6
Croft, S.L.7
-
31
-
-
0030902239
-
Axenically cultured amastigote forms as an in vitro model for investigation of antileishmanial agents
-
Sereno, D., and J.-L. Lemesre. 1997. Axenically cultured amastigote forms as an in vitro model for investigation of antileishmanial agents. Antimicrob. Agents Chemother. 41:972-976.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 972-976
-
-
Sereno, D.1
Lemesre, J.-L.2
-
32
-
-
0031760626
-
Axenically grown amastigotes of Leishmania infantum used as an in vitro model to investigate the pentavalent antimony mode of action
-
Sereno, D., M. Cavaleyra, K. Zemzoumi, S. Maquaire, A. Ouaissi, and J. L. Lemesre. 1998. Axenically grown amastigotes of Leishmania infantum used as an in vitro model to investigate the pentavalent antimony mode of action. Antimicrob. Agents Chemother. 42:3097-3102.
-
(1998)
Antimicrob. Agents Chemother.
, vol.42
, pp. 3097-3102
-
-
Sereno, D.1
Cavaleyra, M.2
Zemzoumi, K.3
Maquaire, S.4
Ouaissi, A.5
Lemesre, J.L.6
-
34
-
-
50549089453
-
Rapid fluorescent assay for screening drugs on Leishmania amastigotes
-
Shimony, O., and C. L. Jaffe. 2008. Rapid fluorescent assay for screening drugs on Leishmania amastigotes. J. Microbiol. Methods 75:196-200.
-
(2008)
J. Microbiol. Methods
, vol.75
, pp. 196-200
-
-
Shimony, O.1
Jaffe, C.L.2
-
35
-
-
0034076993
-
Activity of the novel immunomodulatory compound tucaresol against experimental visceral leishmaniasis
-
Smith, A. C., V. Yardley, J. Rhodes, and S. L. Croft. 2000. Activity of the novel immunomodulatory compound tucaresol against experimental visceral leishmaniasis. Antimicrob. Agents Chemother. 44:1494-1498.
-
(2000)
Antimicrob. Agents Chemother.
, vol.44
, pp. 1494-1498
-
-
Smith, A.C.1
Yardley, V.2
Rhodes, J.3
Croft, S.L.4
-
36
-
-
18944370727
-
Availability of miltefosine for the treatment of kala-azar in India
-
Sundar, S., and H. W. Murray. 2005. Availability of miltefosine for the treatment of kala-azar in India. Bull. W. H. O. 83:394-395.
-
(2005)
Bull. W. H. O.
, vol.83
, pp. 394-395
-
-
Sundar, S.1
Murray, H.W.2
-
37
-
-
18044369645
-
Differential effects of polyamine derivative compounds against Leishmania infantum promastigotes and axenic amastigotes
-
Tavares, J., A. Ouaissi, P. K. Lin, A. Tomás, and A. Cordeiro-da-Silva. 2005. Differential effects of polyamine derivative compounds against Leishmania infantum promastigotes and axenic amastigotes. Int. J. Parasitol. 35:637-646.
-
(2005)
Int. J. Parasitol.
, vol.35
, pp. 637-646
-
-
Tavares, J.1
Ouaissi, A.2
Lin, P.K.3
Tomás, A.4
Cordeiro-da-Silva, A.5
-
38
-
-
0036401219
-
A simple and reproducible method to obtain large numbers of axenic amastigotes of different Leishmania species
-
Teixeira, M. C., R. de Jesus Santos, R. B. Sampaio, L. Pontes-de-Carvalho, and W. L. Dos-Santos. 2002. A simple and reproducible method to obtain large numbers of axenic amastigotes of different Leishmania species. Parasitol. Res. 88:963-968.
-
(2002)
Parasitol. Res.
, vol.88
, pp. 963-968
-
-
Teixeira, M.C.1
De Jesus Santos, R.2
Sampaio, R.B.3
Pontes-de-Carvalho, L.4
Dos-Santos, W.L.5
-
39
-
-
34249930229
-
Comparative analysis of megasomes in members of the Leishmania mexicana complex
-
Ueda-Nakamura, T., M. Attias, and W. de Souza. 2007. Comparative analysis of megasomes in members of the Leishmania mexicana complex. Res. Microbiol. 158:456-462.
-
(2007)
Res. Microbiol.
, vol.158
, pp. 456-462
-
-
Ueda-Nakamura, T.1
Attias, M.2
De Souza, W.3
-
40
-
-
33749341812
-
Mechanisms of action of lysophospholipid analogues against trypanosomatid parasites
-
Urbina, J. A. 2006. Mechanisms of action of lysophospholipid analogues against trypanosomatid parasites. Trans. R. Soc. Trop. Med. Hyg. 100:S9-S16.
-
(2006)
Trans. R. Soc. Trop. Med. Hyg.
, vol.100
-
-
Urbina, J.A.1
|