Monoterpenic aldehydes as potential anti-Leishmania agents: Activity of Cymbopogon citratus and citral on L. infantum, L. tropica and L. major

Experimental Parasitology

Volumn 130, Issue 3, 2012, Pages 223-231

  Machado, M ^a,b   Pires, P ^a,b   Dinis, A M ^c   Santos Rosa, M ^d   Alves, V ^d   Salgueiro, L ^a   Cavaleiro, C ^a   Sousa, M C ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b Instituto Politécnico de Saúde do Norte   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Antiprotozoals; Drug action; Drug development; Essential oil; Flow cytometry; In vitro activity; Infectious diseases (ID); Leishmania infantum; Leishmania major; Leishmania tropica; Medicinal plants; Ultrastructure

Indexed keywords

CITRAL; CYMBOPOGON CITRATUS ESSENTIAL OIL; ESSENTIAL OIL; LIPOCORTIN 5; MYRCENE; PHOSPHATIDYLSERINE; UNCLASSIFIED DRUG;

ACIDOCALCISOME; ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL NUCLEUS MEMBRANE; CELL ORGANELLE; CELL SHAPE; CELL ULTRASTRUCTURE; CHEMICAL COMPOSITION; CHROMATIN CONDENSATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYMBOPOGON CITRATUS; DRUG CYTOTOXICITY; DRUG SENSITIVITY; DRUG STRUCTURE; EXOCYTOSIS; FLAGELLUM; G0 PHASE CELL CYCLE ARREST; G1 PHASE CELL CYCLE CHECKPOINT; IC 50; KINETOPLAST; KINETOPLAST SWELLING; LEISHMANIA INFANTUM; LEISHMANIA MAJOR; LEISHMANIA TROPICA; MEMBRANE DAMAGE; MEMBRANE DEPOLARIZATION; MEMBRANE VESICLE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION SWELLING; NONHUMAN; PRIORITY JOURNAL; PROMASTIGOTE;

ALDEHYDES; ANIMALS; ANTIPROTOZOAL AGENTS; CATTLE; CELL CYCLE CHECKPOINTS; CELL LINE; CYMBOPOGON; FLOW CYTOMETRY; INHIBITORY CONCENTRATION 50; LEISHMANIA; LEISHMANIA INFANTUM; LEISHMANIA MAJOR; LEISHMANIA TROPICA; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; MONOTERPENES; OILS, VOLATILE; PHOSPHATIDYLSERINES; PLANT EXTRACTS;

CYMBOPOGON CITRATUS; LEISHMANIA INFANTUM; LEISHMANIA MAJOR; LEISHMANIA TROPICA;

EID: 84857451544     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2011.12.012     Document Type: Article

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