PKCα phosphorylation of RhoGDI2 at Ser31 disrupts interactions with Rac1 and decreases GDI activity

Oncogene

Volumn 32, Issue 8, 2013, Pages 1010-1017

  Griner, E M ^a   Churchill, M E A ^b,c   Brautigan, D L ^a   Theodorescu, D ^b,c  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF COLORADO CANCER CENTER   (United States)

Author keywords

GTPase; phosphorylation; PKC ; RhoGDI2

Indexed keywords

GUANOSINE TRIPHOSPHATASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C ALPHA; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR 2; SMALL INTERFERING RNA;

ARTICLE; ENZYME ACTIVITY; ENZYME INACTIVATION; GENE SILENCING; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; WILD TYPE;

AMINO ACID SEQUENCE; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN KINASE C-ALPHA; RAC1 GTP-BINDING PROTEIN; RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR BETA; SERINE; TETRADECANOYLPHORBOL ACETATE; TRANSFECTION;

EID: 84874783966     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.124     Document Type: Article

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