메뉴 건너뛰기




Volumn 29, Issue 2, 2013, Pages 200-205

MTORC1 and Sirolimus: A link with fertility;MTORC1 et sirolimus: Un lien avec la fertilité

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; MULTIPROTEIN COMPLEX; RAPAMYCIN; TARGET OF RAPAMYCIN KINASE; TOR COMPLEX 1;

EID: 84874749004     PISSN: 07670974     EISSN: 19585381     Source Type: Journal    
DOI: 10.1051/medsci/2013292019     Document Type: Article
Times cited : (2)

References (35)
  • 1
    • 4644239244 scopus 로고    scopus 로고
    • Mammalian target of rapamycin inhibition
    • Dutcher JP. Mammalian target of rapamycin inhibition. Clin Cancer Res 2004; 10 : 6382S-7S.
    • (2004) Clin Cancer Res , vol.10
    • Dutcher, J.P.1
  • 2
    • 0025776523 scopus 로고
    • Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast
    • Heitman J, Movva NR, Hall MN. Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science 1991; 253 : 905-9.
    • (1991) Science , vol.253 , pp. 905-909
    • Heitman, J.1    Movva, N.R.2    Hall, M.N.3
  • 3
    • 0028239893 scopus 로고
    • RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs
    • Sabatini DM, Erdjument-Bromage H, Lui M, et al. RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs. Cell 1994; 78 : 35-43.
    • (1994) Cell , vol.78 , pp. 35-43
    • Sabatini, D.M.1    Erdjument-Bromage, H.2    Lui, M.3
  • 4
    • 3242721268 scopus 로고    scopus 로고
    • MTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells
    • Murakami M, Ichisaka T, Maeda M, et al. mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells. Mol Cell Biol 2004; 24 : 6710-8.
    • (2004) Mol Cell Biol , vol.24 , pp. 6710-6718
    • Murakami, M.1    Ichisaka, T.2    Maeda, M.3
  • 5
    • 33751348056 scopus 로고    scopus 로고
    • Ablation in mice of the mTORC components raptor, rictor or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCa, but not S6K1
    • Guertin DA, Stevens DM, Thoreen CC, et al. Ablation in mice of the mTORC components raptor, rictor or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCa, but not S6K1. Dev Cell 2006; 11 : 859-71.
    • (2006) Dev Cell , vol.11 , pp. 859-871
    • Guertin, D.A.1    Stevens, D.M.2    Thoreen, C.C.3
  • 6
    • 0032982586 scopus 로고    scopus 로고
    • Régulation endocrine et paracrine de la folliculogenèse
    • Monget P. Régulation endocrine et paracrine de la folliculogenèse. Med Sci (Paris) 1999; 15 : 141-7.
    • (1999) Med Sci (Paris) , vol.15 , pp. 141-147
    • Monget, P.1
  • 7
    • 33646766672 scopus 로고    scopus 로고
    • Insuline, métabolisme énergétique et fertilité
    • Froment P, Holzenberger M, Monget P. Insuline, métabolisme énergétique et fertilité Med Sci (Paris) 2001; 17 : 817-8.
    • (2001) Med Sci (Paris) , vol.17 , pp. 817-818
    • Froment, P.1    Holzenberger, M.2    Monget, P.3
  • 8
    • 18844362191 scopus 로고    scopus 로고
    • Un rôle pour PPARγ dans la reproduction ?
    • Froment P, Gizard F, Staels B, et al. Un rôle pour PPARγ dans la reproduction ? Med Sci (Paris) 2005; 21 : 507-11.
    • (2005) Med Sci (Paris) , vol.21 , pp. 507-511
    • Froment, P.1    Gizard, F.2    Staels, B.3
  • 9
    • 41149143170 scopus 로고    scopus 로고
    • L'AMPK : un lien entre métabolisme et reproduction ?
    • Tosca L, Chabrolle C, Dupont J. L'AMPK : un lien entre métabolisme et reproduction ? Med Sci (Paris) 2008; 24 : 297-300.
    • (2008) Med Sci (Paris) , vol.24 , pp. 297-300
    • Tosca, L.1    Chabrolle, C.2    Dupont, J.3
  • 10
    • 47249138206 scopus 로고    scopus 로고
    • Sirolimus may reduce fertility in male renal transplant recipients
    • Zuber J, Anglicheau D, Elie C, et al. Sirolimus may reduce fertility in male renal transplant recipients. Am J Transplant 2008; 8 : 1471-9.
    • (2008) Am J Transplant , vol.8 , pp. 1471-1479
    • Zuber, J.1    Anglicheau, D.2    Elie, C.3
  • 11
    • 67649666499 scopus 로고    scopus 로고
    • The pregnancy rate and live birth rate in kidney transplant recipients
    • Gill JS, Zalunardo N, Rose C, et al. The pregnancy rate and live birth rate in kidney transplant recipients. Am J Transplant 2009; 9 : 1541-9.
    • (2009) Am J Transplant , vol.9 , pp. 1541-1549
    • Gill, J.S.1    Zalunardo, N.2    Rose, C.3
  • 12
    • 33646023695 scopus 로고    scopus 로고
    • Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
    • Sarbassov DD, Ali SM, Sengupta S, et al. Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol Cell 2006; 22 : 159-68.
    • (2006) Mol Cell , vol.22 , pp. 159-168
    • Sarbassov, D.D.1    Ali, S.M.2    Sengupta, S.3
  • 13
    • 33847235398 scopus 로고    scopus 로고
    • Gonadal impact of target of rapamycin inhibitors (sirolimus and everolimus) in male patients: An overview
    • Huyghe E, Zairi A, Nohra J, et al. Gonadal impact of target of rapamycin inhibitors (sirolimus and everolimus) in male patients: an overview. Transpl Int 2007; 20 : 305-11.
    • (2007) Transpl Int , vol.20 , pp. 305-311
    • Huyghe, E.1    Zairi, A.2    Nohra, J.3
  • 15
    • 35348920085 scopus 로고    scopus 로고
    • Azoospermia in a renal transplant recipient during sirolimus (rapamycin) treatment
    • Skrypek J, Krause W. Azoospermia in a renal transplant recipient during sirolimus (rapamycin) treatment. Andrologia 2007; 39 : 198-9.
    • (2007) Andrologia , vol.39 , pp. 198-199
    • Skrypek, J.1    Krause, W.2
  • 16
    • 0034682805 scopus 로고    scopus 로고
    • Stem cell factor/c-kit Up-regulates cyclin D3 and promotes cell cycle progression via the phosphoinositide 3 kinase/p70 S6 kinase pathway in spermatogonia
    • Feng LX, Ravindranath N, Dym M. Stem cell factor/c-kit Up-regulates cyclin D3 and promotes cell cycle progression via the phosphoinositide 3 kinase/p70 S6 kinase pathway in spermatogonia. J Biol Chem 2000; 275 : 25572-6.
    • (2000) J Biol Chem , vol.275 , pp. 25572-25576
    • Feng, L.X.1    Ravindranath, N.2    Dym, M.3
  • 17
    • 84859150660 scopus 로고    scopus 로고
    • MRNA-selective translation induced by FSH in primary Sertoli cells
    • Musnier A, Leon K, Morales J, et al. mRNA-selective translation induced by FSH in primary Sertoli cells. Mol Endocrinol 2012; 26 : 669-80.
    • (2012) Mol Endocrinol , vol.26 , pp. 669-680
    • Musnier, A.1    Leon, K.2    Morales, J.3
  • 18
    • 67949115627 scopus 로고    scopus 로고
    • Une nouvelle fonction pour la transferrine exprimée par le testicule
    • Fumel B, Sow A, Fouchécourt S, et al. Une nouvelle fonction pour la transferrine exprimée par le testicule. Andrologie (Paris) 2009; 19 : 81-9.
    • (2009) Andrologie (Paris) , vol.19 , pp. 81-89
    • Fumel, B.1    Sow, A.2    Fouchécourt, S.3
  • 19
    • 80755167914 scopus 로고    scopus 로고
    • Autophagic deficiency is related to steroidogenic decline in aged rat Leydig cells
    • Li WR, Chen L, Chang ZJ, et al. Autophagic deficiency is related to steroidogenic decline in aged rat Leydig cells. Asian J Andro 2011; 13 : 881-8.
    • (2011) Asian J Andro , vol.13 , pp. 881-888
    • Li, W.R.1    Chen, L.2    Chang, Z.J.3
  • 20
    • 10644224265 scopus 로고    scopus 로고
    • Alterations of the female reproductive system in recipients of islet grafts
    • Cure P, Pileggi A, Froud T, et al. Alterations of the female reproductive system in recipients of islet grafts. Transplantation 2004; 78 : 1576-81.
    • (2004) Transplantation , vol.78 , pp. 1576-1581
    • Cure, P.1    Pileggi, A.2    Froud, T.3
  • 21
    • 84858257135 scopus 로고    scopus 로고
    • Ovarian toxicity from sirolimus
    • Braun M, Young J, Reiner CS, et al. Ovarian toxicity from sirolimus. N Engl J Med 2012; 366 : 1062- 4.
    • (2012) N Engl J Med , vol.366 , pp. 1062-1064
    • Braun, M.1    Young, J.2    Reiner, C.S.3
  • 22
    • 34547124065 scopus 로고    scopus 로고
    • Follicle-stimulating hormone increases tuberin phosphorylation and mammalian target of rapamycin signaling through an extracellular signal-regulated kinasedependent pathway in rat granulosa cells
    • Kayampilly PP, Menon KM. Follicle-stimulating hormone increases tuberin phosphorylation and mammalian target of rapamycin signaling through an extracellular signal-regulated kinasedependent pathway in rat granulosa cells. Endocrinology 2007; 148 : 3950-7.
    • (2007) Endocrinology , vol.148 , pp. 3950-3957
    • Kayampilly, P.P.1    Menon, K.M.2
  • 23
    • 77956097751 scopus 로고    scopus 로고
    • Human chorionic gonadotropin stimulates theca-interstitial cell proliferation and cell cycle regulatory proteins by a cAMP-dependent activation of Akt/mTORC1 signaling pathway
    • Palaniappan M, Menon KM. Human chorionic gonadotropin stimulates theca-interstitial cell proliferation and cell cycle regulatory proteins by a cAMP-dependent activation of Akt/mTORC1 signaling pathway. Mol Endocrinol 2010; 24 : 1782-93.
    • (2010) Mol Endocrinol , vol.24 , pp. 1782-1793
    • Palaniappan, M.1    Menon, K.M.2
  • 24
    • 79960024518 scopus 로고    scopus 로고
    • MTOR controls ovarian follicle growth by regulating granulosa cell proliferation
    • Yu J, Yaba A, Kasiman C, et al. mTOR controls ovarian follicle growth by regulating granulosa cell proliferation. PLoS One 2011; 6 : e21415.
    • (2011) PLoS One , vol.6
    • Yu, J.1    Yaba, A.2    Kasiman, C.3
  • 25
    • 80055024323 scopus 로고    scopus 로고
    • MTOR kinase inhibition results in oocyte loss characterized by empty follicles in human ovarian cortical strips cultured in vitro
    • McLaughlin M, Patrizio P, Kayisli U, et al. mTOR kinase inhibition results in oocyte loss characterized by empty follicles in human ovarian cortical strips cultured in vitro. Fertil Steril 2011; 96 : 1154-9.
    • (2011) Fertil Steril , vol.96 , pp. 1154-1159
    • McLaughlin, M.1    Patrizio, P.2    Kayisli, U.3
  • 26
    • 2442485795 scopus 로고    scopus 로고
    • Follicle-stimulating hormone activation of hypoxia-inducible factor 1 by phosphatidylinositol 3 kinase/Akt/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation
    • Alam H, Maizels ET, Park Y et al. Follicle-stimulating hormone activation of hypoxia-inducible factor 1 by phosphatidylinositol 3 kinase/Akt/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation. J Biol Chem 2004; 279 : 19431-40.
    • (2004) J Biol Chem , vol.279 , pp. 19431-19440
    • Alam, H.1    Maizels, E.T.2    Park, Y.3
  • 27
    • 79958766333 scopus 로고    scopus 로고
    • Tacrolimus and sirolimus induce reproductive abnormalities in female rats
    • Shivaswamy V, Ochsner L, Maroni D, et al. Tacrolimus and sirolimus induce reproductive abnormalities in female rats. Transplantation 2011; 91 : 1333-9.
    • (2011) Transplantation , vol.91 , pp. 1333-1339
    • Shivaswamy, V.1    Ochsner, L.2    Maroni, D.3
  • 28
    • 34047253075 scopus 로고    scopus 로고
    • RAD001 (everolimus) delays tumor onset and progression in a transgenic mouse model of ovarian cancer
    • Mabuchi S, Altomare DA, Connolly DC, et al. RAD001 (everolimus) delays tumor onset and progression in a transgenic mouse model of ovarian cancer. Cancer Res 2007; 67 : 2408-13.
    • (2007) Cancer Res , vol.67 , pp. 2408-2413
    • Mabuchi, S.1    Altomare, D.A.2    Connolly, D.C.3
  • 29
    • 51049109033 scopus 로고    scopus 로고
    • Identification and development of NVP-BEZ235, a new orally available dual PI3K/mTOR inhibitor with potent in vivo antitumor activity
    • Maira SM, Stauffer F, Brueggen J, et al. Identification and development of NVP-BEZ235, a new orally available dual PI3K/mTOR inhibitor with potent in vivo antitumor activity. Mol Cancer Ther 2008; 7 : 1851-63.
    • (2008) Mol Cancer Ther , vol.7 , pp. 1851-1863
    • Maira, S.M.1    Stauffer, F.2    Brueggen, J.3
  • 30
    • 70350266820 scopus 로고    scopus 로고
    • The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system
    • Roa J, Garcia-Galiano D, Varela L, et al. The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system. Endocrinology 2009; 150 : 5016-26.
    • (2009) Endocrinology , vol.150 , pp. 5016-5026
    • Roa, J.1    Garcia-Galiano, D.2    Varela, L.3
  • 31
    • 78651394781 scopus 로고    scopus 로고
    • MTOR, la cible fonctionnelle de la rapamycine
    • Julien LA, Roux PP. mTOR, la cible fonctionnelle de la rapamycine. Med Sci (Paris) 2010; 26 : 1056-60.
    • (2010) Med Sci (Paris) , vol.26 , pp. 1056-1060
    • Julien, L.A.1    Roux, P.P.2
  • 32
    • 33751556669 scopus 로고    scopus 로고
    • Inhibiteurs de mTOR : Des antiprolifératifs pléiotropiques
    • Pallet N, Beaune P, Thervet E, et al. Inhibiteurs de mTOR : Des antiprolifératifs pléiotropiques. Med Sci (Paris) 2006; 22 : 947-52.
    • (2006) Med Sci (Paris) , vol.22 , pp. 947-952
    • Pallet, N.1    Beaune, P.2    Thervet, E.3
  • 34
    • 84996142961 scopus 로고    scopus 로고
    • La kinase FRAP/mTOR : une nouvelle cible dans le traitement des cancers dépendants de la voie PI3-kinase/PTEN
    • Greenland C, Delsol G, Payrastre B. La kinase FRAP/mTOR : une nouvelle cible dans le traitement des cancers dépendants de la voie PI3-kinase/PTEN. Med Sci (Paris) 2002; 18 : 137-9.
    • (2002) Med Sci (Paris) , vol.18 , pp. 137-139
    • Greenland, C.1    Delsol, G.2    Payrastre, B.3
  • 35
    • 79958745911 scopus 로고    scopus 로고
    • Inhibition thérapeutique de mTOR dans la polykystose rénale autosomique dominante
    • Joly D. Inhibition thérapeutique de mTOR dans la polykystose rénale autosomique dominante. Med Sci (Paris) 2011; 27 : 249-51.
    • (2011) Med Sci (Paris) , vol.27 , pp. 249-251
    • Joly, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.