Rapamycin-induced oligospermia [3]

Transplantation

Volumn 76, Issue 5, 2003, Pages 885-886

  Bererhi, Lynda ^a   Flamant, Martin ^a   Martinez, Frank ^a   Karras, Alexandre ^a   Thervet, Eric ^a   Legendre, Christophe ^a  

^a SAINT LOUIS HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; CYCLOSPORIN; MACROLIDE; PREDNISONE; RAPAMYCIN; TACROLIMUS;

ADULT; CASE REPORT; CREATININE BLOOD LEVEL; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY TRANSPLANTATION; LETTER; MALE; MALE INFERTILITY; OLIGOSPERMIA; PRIORITY JOURNAL; SEMEN ANALYSIS;

ADULT; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; MALE; OLIGOSPERMIA; SIROLIMUS;

EID: 0141590390     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000079830.03841.9E     Document Type: Letter

References (5)

1. Baker H, Sidorowicz A, Sehgal SN, et al. Rapamycin (AY-22, 989), a new antifungal antibiotic. III. In vitro and in vivo evaluation. J Antibiot (Tokyo) 1978; 31: 539.
2. Seufferlein T, Rozengurt E. Rapamycin inhibits constitutive p70s6k phosphorylation, cell proliferation, and colony formation in small cell lung cancer cells. Cancer Res 1996; 56: 3895.
3. Feng LX, Ravindranath N, Dym M. Stem cell factor/c-kit up-regulates cyclin D3 and promotes cell cycle progression via the phosphoinositide 3-kinase/ p70 S6 kinase pathway in spermatogonia. J Biol Chem 2000; 275: 25572.
4. Blume-Jensen P, Jiang G, Hyman R, et al. Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3′-kinase is essential for male fertility. Nat Genet 2000; 24: 157.
5. Comitee for proprietary Medicinal Products. European Public Assesment Report (EPAR) - Rapamune. June 2002. Available from: URL://www. emea.eu.int/