MTOR kinase inhibition results in oocyte loss characterized by empty follicles in human ovarian cortical strips cultured in vitro

Fertility and Sterility

Volumn 96, Issue 5, 2011, Pages

  McLaughlin, Marie ^a   Patrizio, Pasquale ^b   Kayisli, Umit ^b   Luk, Janelle ^b   Thomson, Travis C ^c   Anderson, Richard A ^d   Telfer, Evelyn E ^a   Johnson, Joshua ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Atresia; empty follicle syndrome; fertility; follicle; mTOR kinase; oocyte; ovary

Indexed keywords

CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR;

ADOLESCENT; ADULT; APOPTOSIS; ARTICLE; CESAREAN SECTION; CONTROLLED STUDY; FEMALE; FERTILITY; GRANULOSA CELL; GYNECOLOGIC SURGERY; HUMAN; HUMAN CELL; HUMAN OVARIAN CORTICAL STRIP; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; OBSTETRICS; OOCYTE; OVARIAN CORTEX; OVARIECTOMY; OVARY; OVARY FOLLICLE; PHAGOCYTOSIS; PRIORITY JOURNAL;

EID: 80055024323     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2011.08.040     Document Type: Article

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